CN105396187A - Extra corporeal membrane oxygenation device - Google Patents
Extra corporeal membrane oxygenation device Download PDFInfo
- Publication number
- CN105396187A CN105396187A CN201511016962.7A CN201511016962A CN105396187A CN 105396187 A CN105396187 A CN 105396187A CN 201511016962 A CN201511016962 A CN 201511016962A CN 105396187 A CN105396187 A CN 105396187A
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- blood
- channel
- passage
- gas exchange
- exchange units
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
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- Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention provides an extra corporeal membrane oxygenation device which comprises a shell and at least two gas exchange units. An oxygenation chamber is formed in the shell and internally provided with a blood channel, a blood inlet and a blood outlet, and the blood inlet and the blood outlet are located in the two ends of the blood channel. The oxygenation chamber is further internally provided with an oxygen channel, a gas inlet and a gas outlet, and the gas inlet and the gas outlet are located in the two ends of the oxygen channel. Each gas exchange unit is woven into a preset shape through polymer fiber tubular products and is fixedly arranged in the oxygenation chamber and close to the blood channel and the gas channel so that oxygen in the gas channel can penetrate through the gas exchange unit to enter the blood channel. By arranging the two gas exchange units, in the production and manufacture process, the length of applied single fiber tubes can be reduced by half, and therefore the process difficulty of production and manufacture is lowered, and fiber tubes can be easily woven into the preset shape.
Description
Technical field
The present invention relates to technical field of medical instruments, be specifically related to a kind of ECMO oxygenator structure.
Background technology
ECMO technology (ECMO) is " artificial lung " set up beyond human body, mainly play part pulmonary function vicarious function, pulmonary function is supported on the basis of not increasing the weight of protopathy, effect by extracorporeal circulation allows organ do self-regeneration, maintain human internal organ tissue oxygenation blood to supply, thus the sign that effectively sustains life, for the impaired internal organs of successive treatment provide time enough.Oxygenator is the core devices of Portable lung function supportive device.
Usually all-in-one-piece gas exchange units is provided with in the oxygenation chamber of the oxygenator for external Breathing Suppotion conventional at present, a kind of portable pump-free type ECMO disclosed in Chinese patent CN202459508U, there is following technological deficiency in this oxygenator: because gas exchange units adopts integral structure, single fiber pipe like this for being woven into gas exchange units just must have enough length, Zhong is capable repeatedly to be bent and weaves, so just the difficulty of processing technique is increased, reduce yields, add production cost.
Summary of the invention
Therefore, it is high that the technical problem to be solved in the present invention is to overcome extracorporeal membrane oxygenation device processing technique difficulty of the prior art, the technological deficiency that production cost is high.
For solving the problems of the technologies described above, the invention provides a kind of extracorporeal membrane oxygenation device, comprising:
Housing, inner formation oxygenation chamber, has blood channel and the Zhong blood mouth, the blood outlet that are positioned at described blood channel two ends in described oxygenation chamber; Also there is in described oxygenation chamber oxygen channel and the Zhong QI KOU, the gas outlet that are positioned at described oxygen channel two ends;
At least two group gas exchange units, reservation shape is woven into by polymer fiber tubing, and be fixedly installed in described oxygenation chamber near described blood channel and described gas passage simultaneously, enter in described blood channel through described gas exchange units Zhong to enable the oxygen in described gas passage.
In above-mentioned extracorporeal membrane oxygenation device, described blood channel comprises the Zhong blood passage being arranged on described oxygenation chamber side and the hemorrhage passage being positioned at described oxygenation chamber opposite side, and connects the interface channel of described Zhong blood passage and described hemorrhage passage;
Described gas exchange units is two groups, and respectively around described Zhong blood passage and described hemorrhage channel setting.
In above-mentioned extracorporeal membrane oxygenation device, described oxygenation chamber is regular hexagon;
The regular hexagon structure that some equilateral triangle structures that described gas exchange units is woven into by described polymer fiber tubing form.
In above-mentioned extracorporeal membrane oxygenation device, be also included in top and connect the encapsulating housing often organizing described gas exchange units, gas exchange units described in some groups connects in aggregates by described encapsulating housing.
In above-mentioned extracorporeal membrane oxygenation device, described oxygen channel is arranged between described Zhong blood passage and described hemorrhage passage, and described Zhong QI KOU is positioned at the bottom of described oxygenation chamber; Described gas outlet is two, and lays respectively at the both sides of described oxygenation chamber.
In above-mentioned extracorporeal membrane oxygenation device, described housing also comprises the shell of inner shell and the described inner shell setting of parcel;
The two ends of described inner shell and described shell use resin seal.
In above-mentioned extracorporeal membrane oxygenation device, also comprise the bubble eliminating structure for eliminating bubble in described blood channel, described bubble eliminating structure comprises: extended in described oxygenation chamber by the resin of described shell upper end, and the bubble being communicated with described interface channel eliminates passage.
Accompanying drawing explanation
In order to be illustrated more clearly in the specific embodiment of the invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in detailed description of the invention or description of the prior art below, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is the cross-sectional schematic of oxygenator of the present invention;
Fig. 2 is the front view of oxygenator of the present invention;
Fig. 3 is the structural representation of gas exchange units in the present invention.
Description of reference numerals:
10-housing; 111-Zhong blood mouth; 121-blood outlet; 131-Zhong QI KOU; 132-gas outlet; 20-gas exchange units; 11-Zhong blood passage; The hemorrhage passage of 12-; 13-interface channel; 30-encapsulating housing; 14-inner shell; 15-shell; 16-bubble eliminates passage.
Detailed description of the invention
Describe clearly and completely technical scheme Zhong of the present invention is capable below in conjunction with accompanying drawing, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
In describing the invention, it should be noted that, orientation or the position relationship of the instruction such as term " " center ", " on ", D score, "left", "right", " vertically ", " level ", " interior ", " outward " they be based on orientation shown in the drawings or position relationship; be only the present invention for convenience of description and simplified characterization; instead of instruction or imply the device of indication or element must have specific orientation, with specific azimuth configuration and operation, therefore can not be interpreted as limitation of the present invention.In addition, term " first ", " second ", " the 3rd " only for describing object, and can not be interpreted as instruction or hint relative importance.
In describing the invention, it should be noted that, unless otherwise clearly defined and limited, term " installation ", " being connected ", " connection " should be interpreted broadly, and such as, can be fixedly connected with, also can be removably connect, or connect integratedly; Can be mechanical connection, also can be electrical connection; Can be directly be connected, also indirectly can be connected by intermediary, can be the connection of two element internals.For the ordinary skill in the art, specifically above-mentioned term concrete meaning in the present invention can be understood by feelings Saeka.
In addition, if below in the described different embodiment of the present invention involved technical characteristic do not form conflict each other and just can be combined with each other.
Embodiment 1
With reference to figure 1 and Fig. 2, the present embodiment provides a kind of extracorporeal membrane oxygenation device, comprise: housing 10 and gas exchange units 20, the inside of housing 10 forms oxygenation chamber, has blood channel and the Zhong blood mouth 111, the blood outlet 121 that are positioned at described blood channel two ends in oxygenation chamber; Also there is in oxygenation chamber oxygen channel and the Zhong QI KOU 131, the gas outlet 132 that are positioned at described oxygen channel two ends.When reality uses, blood and oxygen are simultaneously respectively by blood channel and oxygen channel, oxygen in oxygen channel enters in the blood in blood channel through gas exchange units 20 Zhong, carbon dioxide in blood then enters to oxygen channel from blood channel through gas exchange units 20 Zhong, and discharges from gas outlet 132.The gas exchange units that existing oxygenator generally adopts is an entirety, and this design makes the length of the single fiber pipe forming gas exchange units longer, is beneficial to braiding on the one hand, the technology difficulty of the manufacturing is increased; Meanwhile, also make yields decrease, in a disguised form improve production cost.
As one preferred embodiment, two groups of gas exchange units 20 are provided with in oxygenation chamber, reservation shape is woven into by polymer fiber tubing, and be fixedly installed in described oxygenation chamber near described blood channel and described gas passage simultaneously, more preferably two groups of gas exchange units 20 are arranged around described Zhong blood passage 11 and described hemorrhage passage 12 respectively, , enter in described blood channel to enable the oxygen in described gas passage through described gas exchange units 20 Zhong, two groups of gas exchange units 20 be arranged so that manufacture process in, the length of the single fiber pipe used can reduce half, thus reduce the technology difficulty of the manufacturing, fiber pipe is conducive to be woven into predetermined shape.
Preferred as one, with reference to figure 3, the adjacent fiber pipe in gas exchange units 20 is preferably woven into equilateral triangle, then is arranged in order by multiple equilateral triangle thus forms regular hexagon structure.The gas exchange units 20 of regular hexagon structure can effectively avoid blood flow dead angle, makes gas exchange more abundant.
It should be noted that; in the present embodiment, the quantity of gas exchange units 20 preferably but be not limited to be two groups; those skilled in the art can in conjunction with above description; certain adaptive amendment is made to the quantity of gas exchange units 20 and the concrete set-up mode in oxygenation chamber, but it should be encompassed within protection scope of the present invention.
The concrete set-up mode of the extracorporeal membrane oxygenation device of the present embodiment is described in detail below in conjunction with Fig. 1 and Fig. 2:
First with reference to figure 1, housing 10 comprises the shell 15 of inner shell 14 and the setting of parcel inner shell 14, the two ends of inner shell 15 and shell 14 use resin seal, Zhong blood mouth 111, blood outlet 121, Zhong QI KOU 131, gas outlet 132, be separately positioned on shell 14 or resin seal place, the space formed in housing 10 is oxygenation chamber.The cross section of oxygenation chamber is regular hexagon, and being provided with group cross section in it is orthohexagonal gas exchange units 20.Blood channel comprises the Zhong blood passage 11 being arranged on oxygenation chamber side and the hemorrhage passage 12 being positioned at oxygenation chamber opposite side, and connect the interface channel 13 of Zhong blood passage 11 and hemorrhage passage 12, oxygen channel is arranged between Zhong blood passage 11 and hemorrhage passage 12, and described Zhong QI KOU 131 is positioned at the bottom of described oxygenation chamber; Gas outlet 132 is two, and lays respectively at the both sides of described oxygenation chamber.
In actual use, blood enters to Zhong blood passage 11 from Zhong blood mouth 111 Zhong, and through interface channel 13 and hemorrhage passage 12, finally flowed out by blood outlet 121, above-mentioned blood Zhong goes out in flow process, carbon dioxide in blood enters in oxygen channel through gas exchange units 20 Zhong, and discharges from the gas outlet 132 of oxygen channel.Originally the oxygen entered from Zhong QI KOU 131 Zhong in oxygen channel also enters in oxygen through gas exchange units 20 Zhong, thus reduces the concentration of carbon dioxide in blood, and oxygen is combined with blood, thus completes oxygenate process.
Zhong mono-step, for the ease of production and processing, gas exchange units 20 preferably adopts the design of modular form, and above two groups of gas exchange units 20, be provided with encapsulating housing 30, two groups of gas exchange units 20 connect in aggregates by encapsulating housing 30.Like this in the course of processing, the assembly that gas exchange units 20 and encapsulating housing 30 are formed can directly be installed in the oxygenation chamber in housing 10 by staff, can complete assembly working, thus contribute to enhancing productivity.
With reference to figure 1, in order to eliminate in blood channel the air be mixed into, these air are prevented to be back in human body from blood outlet 121, the extracorporeal membrane oxygenation device of the present embodiment also comprises the bubble eliminating structure for eliminating bubble in described blood channel, bubble eliminating structure comprises: extended in oxygenation chamber by the resin of shell 15 upper end, and the bubble being communicated with interface channel 13 eliminates passage 16.Travel up to the process of interface channel at blood from Zhong blood passage, the bubble be mixed in it will float, and after Zhong enters interface channel 13, be close to the roof flowing of interface channel 13, when eliminating after passage 16 through bubble, bubble in blood will break, and is overflowed by bubble elimination passage 16.
Obviously, above-described embodiment is only for clearly example being described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of extending out or variation be still among the protection domain of the invention.
Claims (7)
1. an extracorporeal membrane oxygenation device, is characterized in that, comprising:
Housing (10), inner formation oxygenation chamber, has blood channel and the blood inlet (111), the blood outlet (121) that are positioned at described blood channel two ends in described oxygenation chamber; Also there are in described oxygenation chamber oxygen channel and the air inlet (131), gas outlet (132) that are positioned at described oxygen channel two ends;
At least two group gas exchange units (20), reservation shape is woven into by polymer fiber tubing, and be fixedly installed in described oxygenation chamber near described blood channel and described gas passage simultaneously, enter in described blood channel through described gas exchange units (20) to enable the oxygen in described gas passage.
2. extracorporeal membrane oxygenation device according to claim 1, is characterized in that, comprising:
Described blood channel comprises and is arranged on entering blood passage (11) and being positioned at the hemorrhage passage (12) of described oxygenation chamber opposite side of described oxygenation chamber side, and enters the interface channel (13) of blood passage (11) and described hemorrhage passage (12) described in connecting;
Described gas exchange units (20) is two groups, and respectively around described enter blood passage (11) and described hemorrhage passage (12) arrange.
3. extracorporeal membrane oxygenation device according to claim 2, is characterized in that:
Described oxygenation chamber is regular hexagon;
The regular hexagon structure that some equilateral triangle structures that described gas exchange units (20) is woven into by described polymer fiber tubing form.
4. the extracorporeal membrane oxygenation device according to claim 1-3, is characterized in that:
Also be included in top and connect the encapsulating housing (30) often organizing described gas exchange units (20), gas exchange units described in some groups (20) connects in aggregates by described encapsulating housing (30).
5. extracorporeal membrane oxygenation device according to claim 2, is characterized in that:
Enter described in described oxygen channel is positioned between blood passage (11) and described hemorrhage passage (12) and arrange, and described air inlet (131) is positioned at the bottom of described oxygenation chamber; Described gas outlet (132) is two, and lays respectively at the both sides of described oxygenation chamber.
6. extracorporeal membrane oxygenation device according to claim 1, is characterized in that:
Described housing (10) also comprises inner shell (14) and parcel described inner shell (14) shell (15) that arranges;
The two ends of described inner shell (14) and described shell (15) use resin seal.
7. extracorporeal membrane oxygenation device according to claim 6, is characterized in that:
Also comprise the bubble eliminating structure for eliminating bubble in described blood channel, described bubble eliminating structure comprises: extended in described oxygenation chamber by the resin of described shell (15) upper end, and the bubble being communicated with described interface channel (13) eliminates passage (16).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201511016962.7A CN105396187B (en) | 2015-12-29 | 2015-12-29 | A kind of extracorporeal membrane oxygenation device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201511016962.7A CN105396187B (en) | 2015-12-29 | 2015-12-29 | A kind of extracorporeal membrane oxygenation device |
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| CN105396187A true CN105396187A (en) | 2016-03-16 |
| CN105396187B CN105396187B (en) | 2018-11-30 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421949A (en) * | 2016-08-29 | 2017-02-22 | 安徽通灵仿生科技有限公司 | Oxygenation drainage tube, oxygenation device and oxygenation method |
| CN113082339A (en) * | 2021-04-15 | 2021-07-09 | 上海超高环保科技股份有限公司 | Method for manufacturing ultra-high molecular artificial lung |
| CN117122814A (en) * | 2023-10-25 | 2023-11-28 | 北京航天长峰股份有限公司 | Pump head oxygenator assembly and extracorporeal membrane pulmonary oxygenation system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113082339A (en) * | 2021-04-15 | 2021-07-09 | 上海超高环保科技股份有限公司 | Method for manufacturing ultra-high molecular artificial lung |
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| CN117122814A (en) * | 2023-10-25 | 2023-11-28 | 北京航天长峰股份有限公司 | Pump head oxygenator assembly and extracorporeal membrane pulmonary oxygenation system |
| CN117122814B (en) * | 2023-10-25 | 2024-02-02 | 北京航天长峰股份有限公司 | Pump head oxygenator assembly and extracorporeal membrane pulmonary oxygenation system |
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| CN105396187B (en) | 2018-11-30 |
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