CN115192807A - Oxygenator and extracorporeal membrane lung oxygenating device - Google Patents
Oxygenator and extracorporeal membrane lung oxygenating device Download PDFInfo
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- CN115192807A CN115192807A CN202210891858.6A CN202210891858A CN115192807A CN 115192807 A CN115192807 A CN 115192807A CN 202210891858 A CN202210891858 A CN 202210891858A CN 115192807 A CN115192807 A CN 115192807A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/369—Temperature treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
Abstract
The invention discloses an oxygenator and an extracorporeal membrane oxygenation device, wherein the oxygenator comprises: a housing; the oxygenation chamber is arranged in the shell, and a blood circulation pipeline of the oxygenation chamber passes through the blood inlet and the blood outlet; and the clapboard is arranged between the shell and the oxygenation chamber, the arrangement direction of the clapboard is the same as that of the upper end cover, and the inner part of the shell is divided into a heat medium cavity and an air cavity. The oxygenator provided by the invention is based on multi-objective multi-parameter optimization research such as hemodynamics and qi and blood exchange, and combines the design of the heat medium cavity and the air cavity to carry out brand new optimization design on the membrane lung blood flow path, the air pipeline and the heat medium pipeline, so that the oxygenator has the advantages of optimal hemodynamic performance, uniform distribution of internal flow field and pressure field, small flow retention area, low blood flow resistance, high qi and blood exchange efficiency and heat exchange efficiency, and thus the effect of long-term support of the oxygenator is improved, the occurrence probability of thrombus during long-term support is reduced, and the blood compatibility of the oxygenator is improved.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an oxygenator and an extracorporeal membrane lung oxygenating device.
Background
In vitro membrane pulmonary oxygenation (ECMO) represents the most advanced technology of equipment in the field of extracorporeal circulation, belongs to high-end medical equipment for severe case treatment, relates to multiple disciplines such as biomechanics, hydromechanics, mechanical engineering, biological materials and medicine, is typical medical fusion, is a multidisciplinary cross product, and is difficult to research and develop. The development and production capacity of the ECMO represent the high-end medical instrument technological level of a country to a certain extent. ECMO plays a vital role in the treatment of patients with cardiopulmonary distress caused by infectious diseases or other reasons, and is also widely applied to the first aid and treatment aspects of neonatal cardiac and respiratory failure, adult acute respiratory syndrome, cardiac arrest, in-operation extracorporeal circulation assistance, cardiogenic or post-operation shock, transfer of critical patients and the like. At present, china has no domestic ECMO, all clinical products are imported, the quantity is scarce, the price is high, the medical and health burden is heavy, and public safety emergency response is limited by people.
The membrane oxygenator (membrane lung) is a key device in the ECMO system, and the main functions are blood oxygen exchange and carbon dioxide removal. Manufacturers who have membrane lung development capability in the world currently focus on germany, the united states, italy, and japan, such as micheovir (Maquet), medtronic (Medtronic), sorin (Sorin), tylocene (Terumo) in japan, meduos (Medos), and the like, wherein micheovir, medtronic, and Sorin occupy the first three global markets.
The internal main structure of the membrane lung is a hollow fiber membrane silk, which is a key core material for the membrane lung to exchange qi and blood. When the membrane lung works, high-concentration oxygen is introduced into the inner cavity of the hollow fiber membrane wire, and venous blood flows through the outer part of the hollow fiber membrane wire. The oxygen concentration inside the membrane silk is higher than the oxygen concentration of the venous blood outside the membrane silk, and the concentration of carbon dioxide in the venous blood is higher than the concentration of carbon dioxide inside the membrane silk, so that oxygen is transmitted to the blood from the inside of the membrane silk for blood oxygen exchange, and carbon dioxide is transmitted to the inside of the membrane silk from the blood and is taken away, thereby realizing the qi-blood exchange.
In the development and design of the membrane lung, the design of the blood flow path, the gas path and the heat exchange water path (i.e. the heat medium path) is very important, and these directly affect the qi and blood exchange performance, the blood compatibility and the heat transfer performance of the membrane lung, for example: if the blood flow path is not designed well, the resistance of the blood passing through the membrane lung is high, and the damage of the blood flowing through the membrane thread can be increased; a plurality of flow dead zones are generated in the membrane lung, so that harmful substances in blood can be deposited, and the occurrence probability of thrombus is increased; however, if the membrane lung gas path (i.e. gas line) is not designed well, the efficiency of qi and blood exchange will be low, and the membrane lung function will be directly affected. Although a large number of patients are treated by the ECMO membrane lung clinically used at present, the problems of high thrombus occurrence rate and low qi-blood exchange efficiency still exist after long-time support. This is related to the fact that the whole blood flow path and air path of the membrane lung are not well designed, a large number of flow dead zones exist, blood is easy to be retained, red blood cells after blood oxygen exchange cannot be discharged in time, and other red blood cells cannot perform blood oxygen exchange. The occurrence of thrombus can directly affect the membrane lung function and reduce the efficiency of qi and blood exchange.
Disclosure of Invention
Objects of the invention
The invention aims to provide an oxygenator and an extracorporeal membrane lung oxygenating device, which solve the technical problem that blood is retained due to a flow dead zone of the oxygenator in the prior art.
(II) technical scheme
To solve the above problems, a first aspect of the present invention provides an oxygenator including: the shell is provided with an upper end cover and a lower end cover which are oppositely arranged, and the upper end cover is connected with the lower end cover through a side wall; a blood inlet is formed in the center of the upper end cover, and a blood outlet is formed in one end, close to the side wall, of the lower end cover of the shell; an oxygenation chamber disposed within the housing, blood entering the oxygenation chamber through the blood inlet, oxygenated blood exiting through the blood outlet; and the partition is arranged between the shell and the oxygenation chamber, the arrangement direction of the partition is the same as that of the upper end cover, and the interior of the shell is divided into a heat medium cavity and an air cavity.
Furthermore, a heat medium inlet and a heat medium outlet are formed in the side wall of the shell, a heat medium enters the heat medium cavity through the heat medium inlet, and the heat medium subjected to heat exchange is discharged through the heat medium outlet.
Furthermore, a first isolating part and a second isolating part are further arranged in the heat medium cavity, and the first isolating part and the second isolating part divide the heat medium cavity into a first heat medium cavity and a second heat medium cavity; the first heating medium cavity is communicated with the heating medium inlet, and the second heating medium cavity is communicated with the heating medium outlet; the first heat medium cavity is communicated with the second heat medium cavity through a heat medium pipeline, and the heat medium pipeline penetrates through the oxygenation chamber.
Further, the first partition is disposed between the housing and the oxygenation chamber and near one end of the blood outlet; the second isolation part is arranged between the shell and the oxygenation chamber and is far away from one end of the blood outlet; the first separator and the second separator divide the heating medium cavity into the first heating medium cavity and the second heating medium cavity which are the same in size.
Further, the heat medium inlet and the heat medium outlet are provided at one end of the side wall of the housing near the blood outlet; the oxygenation chamber is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber are communicated through the heat medium pipeline.
Furthermore, a gas inlet and a gas outlet are formed in the side wall of the shell, oxygen-containing gas enters the gas cavity through the gas inlet, and gas after qi-blood exchange is discharged through the gas outlet.
Furthermore, a third isolation part and a fourth isolation part are arranged in the air cavity, and the air cavity is divided into a first air cavity and a second air cavity by the third isolation part and the fourth isolation part; the first air cavity is communicated with the air inlet, and the second air cavity is communicated with the air outlet; the first air cavity is communicated with the second air cavity through a gas pipeline, and the gas pipeline penetrates through the oxygenation chamber.
Further, the third isolation part and the fourth isolation part are respectively arranged at two ends of the blood outlet; the third separator and the fourth separator divide the heat medium cavity into the first air cavity and the second air cavity which have the same size.
Further, the gas inlet is arranged at one end of the side wall of the shell far away from the blood outlet; the gas outlet is arranged at one end of the side wall of the shell close to the blood outlet; the oxygenation chamber is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber are communicated through the gas pipeline.
According to another aspect of the present invention, there is provided an extracorporeal membrane pulmonary oxygenation device comprising an oxygenator according to any one of the above-mentioned aspects.
(III) advantageous effects
The technical scheme of the invention has the following beneficial technical effects:
the oxygenator provided by the invention is based on multi-objective multi-parameter optimization research such as hemodynamics and qi and blood exchange, and combines the design of the heat medium cavity and the air cavity to carry out brand new optimization design on the membrane lung blood flow path, the air pipeline and the heat medium pipeline, so that the oxygenator has the advantages of optimal hemodynamic performance, uniform distribution of internal flow field and pressure field, small flow retention area, low blood flow resistance, high qi and blood exchange efficiency and heat exchange efficiency, and thus the effect of long-term support of the oxygenator is improved, the occurrence probability of thrombus during long-term support is reduced, and the blood compatibility of the oxygenator is improved.
Drawings
FIG. 1 is a schematic diagram of an oxygenator configuration according to an embodiment of the present invention.
Fig. 2 is a schematic structural view of an oxygenator according to another embodiment of the present invention.
Fig. 3 is a schematic structural view of an oxygenator according to still another embodiment of the present invention.
FIG. 4 is a perspective view of an oxygenator according to an embodiment of the present invention.
Fig. 5 is a perspective view of an oxygenator according to another embodiment of the present invention.
Fig. 6 is a perspective view of an oxygenator according to yet another embodiment of the present invention.
FIG. 7 is a schematic diagram of an oxygenation chamber configuration according to an embodiment of the invention.
Fig. 8 is a schematic view of a structure of a heat medium chamber according to an embodiment of the present invention.
FIG. 9 is a schematic diagram of an air cavity structure according to an embodiment of the present invention.
Reference numerals:
100: a housing; 110: a blood inlet; 120: a blood outlet; 130: a heating medium inlet; 140: a heating medium outlet; 150: a gas inlet; 160: a gas outlet; 170: a first exhaust port; 180: a second exhaust port; 200: an oxygenation chamber; 300: a partition plate; 400: a heating medium cavity; 410: a first isolation section; 420: a second isolation portion; 430: a first heating medium cavity; 440: a second heating medium cavity; 500: an air cavity; 510: a third isolation section; 520: a fourth isolation portion; 530: a first air cavity; 540: a second air cavity; 600: an upper end cover; 700: and a lower end cover.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the accompanying drawings in combination with the embodiments. It should be understood that the description is intended to be exemplary only, and is not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.
In the drawings a schematic view of a layer structure according to an embodiment of the invention is shown. The figures are not drawn to scale, wherein certain details are exaggerated and possibly omitted for clarity. The shapes of various regions, layers, and relative sizes and positional relationships therebetween shown in the drawings are merely exemplary, and deviations may occur in practice due to manufacturing tolerances or technical limitations, and a person skilled in the art may additionally design regions/layers having different shapes, sizes, relative positions, as actually required.
It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
The invention will be described in more detail below with reference to the accompanying drawings. Like elements in the various figures are denoted by like reference numerals. For purposes of clarity, the various features in the drawings are not drawn to scale.
At present, the oxygenator in the prior art has the problems of high thrombus incidence rate, reduced qi and blood exchange efficiency, increased resistance of blood flowing through the membrane lung and the like in the clinical use, and the problems can reduce the blood compatibility of the membrane lung, influence the efficacy of the membrane lung and increase the risk of a patient.
As shown in fig. 1, 2, 3, 4, 5 and 6, in an embodiment of the present invention, there is provided an oxygenator, which may include: the shell 100 is provided with an upper end cover 600 and a lower end cover 700 which are oppositely arranged, and the upper end cover 600 is connected with the lower end cover 700 through a side wall; a blood inlet 110 is arranged at the center of the upper end cover 600, and a blood outlet 120 is arranged at one end of the lower end cover 700 of the shell 100 close to the side wall; an oxygenation chamber 200 disposed in the housing 100, the blood entering the oxygenation chamber 200 through the blood inlet 110, the oxygenated blood being discharged through the blood outlet 120; a partition 300 disposed between the housing 100 and the oxygenation chamber 200, the partition 300 being disposed in the same direction as the upper cap 600, dividing the interior of the housing 100 into a heat medium chamber 400 and an air chamber 500.
On the basis of multi-objective multi-parameter optimization research such as hemodynamics and qi-blood exchange, the oxygenator provided by the invention combines the design of the heat medium cavity 400 and the air cavity 500, and performs brand new optimization design on a membrane lung blood flow path (namely, blood flows from the oxygenation chamber 200 into the oxygenation chamber 200 through the blood inlet 110 and flows out from the blood outlet 120 after heat exchange with a heat medium and qi-blood exchange with air), an air pipeline and a heat medium pipeline, so that the oxygenator has the advantages of optimal hemodynamics performance, uniform internal flow field, uniform pressure field distribution, small flow retention area, low blood flow resistance, high qi-blood exchange efficiency and heat exchange efficiency, improved long-term support effect, reduced thrombus generation probability during long-term support and improved oxygenator blood compatibility.
In an alternative embodiment, the septum 300 extends through the oxygenation chamber 200; wherein a plurality of through holes are provided on the partition plate 300 in the oxygenation chamber 200. Blood flows into the oxygenation chamber 200 through the blood inlet 110, passes through the through hole after heat exchange through the heat medium pipeline of the heat medium cavity 400, is ventilated through the gas pipeline of the gas cavity 500 to complete a respiration process, and finally flows out through the blood outlet 120.
In an alternative embodiment, housing 100 may further have a first exhaust port 170, where first exhaust port 170 is disposed on upper cover 600, and first exhaust port 170 is communicated with heating medium chamber 400. First exhaust port 170 is used to inject heating medium to remove air from heating medium chamber 400 prior to use of the oxygenator.
In an alternative embodiment, a sealing cover is disposed at an end of the first exhaust port 170 away from the heating medium chamber 400.
In an alternative embodiment, a second exhaust port 180 may be further disposed on the housing 100, the first exhaust port 170 is disposed on the lower end cap 700, and the second exhaust port 180 is communicated with the oxygenation chamber 200. The second vent 180 is used to inject blood to vent air from the oxygenation chamber 200 prior to use of the oxygenator.
In an alternative embodiment, the second vent 180 is also used to vent small amounts of gas generated by the oxygenation chamber 200 during use of the oxygenator.
In an alternative embodiment, a sealing cover is disposed at an end of the second air outlet 180 away from the oxygenation chamber 200.
FIG. 7 is a schematic diagram of an oxygenation chamber configuration according to an embodiment of the invention.
As shown in fig. 7, the direction of the arrow in fig. 7 is a path through which blood (blood) flows, and the blood in the blood line flows from the blood inlet 110 into the oxygenation chamber 200, exchanges heat through the heat medium line of the heat medium chamber 400, then exchanges air through the gas line of the gas chamber 500, completes a respiration process, and finally flows out from the blood outlet 120.
Fig. 8 is a schematic view of a heating medium chamber according to an embodiment of the present invention.
In an alternative embodiment, as shown in fig. 8, a heat medium inlet 130 is provided on a sidewall of the casing 100, and the heat medium inlet 130 is used for delivering heat medium into the heat medium chamber 400.
In an alternative embodiment, a heat medium outlet 140 is formed in a sidewall of the casing 100, and the heat medium outlet 140 is used for discharging the heat medium after heat exchange in the heat medium chamber 400.
In an alternative embodiment, a first separator 410 and a second separator 420 are also provided within the heating medium chamber 400, with the first separator 410 and the second separator 420 separating the heating medium chamber 400 into a first heating medium chamber 430 and a second heating medium chamber 440.
In an alternative embodiment, the first heating medium chamber 430 is communicated with the heating medium inlet 130, and the second heating medium chamber 440 is communicated with the heating medium outlet 140.
In an alternative embodiment, the first heating medium chamber 430 is in communication with the second heating medium chamber 440 via a heating medium line that passes through the oxygenation chamber 200.
In an alternative embodiment, the first isolation portion 410 is disposed between the housing 100 and the oxygenation chamber 200 near one end of the blood outlet 120.
In an alternative embodiment, the second isolation portion 420 is disposed between the housing 100 and the oxygenation chamber 200 at an end remote from the blood outlet 120.
In an alternative embodiment, the first and second partitions 410 and 420 divide the heating medium chamber 400 into the first and second heating medium chambers 430 and 440 having the same size.
In an alternative embodiment, the heating medium inlet 130 and the heating medium outlet 140 are disposed at one end of the sidewall of the case 100 near the blood outlet 120.
In an alternative embodiment, the oxygenation chamber 200 has a quadrangular prism structure, and two opposite sides of the oxygenation chamber 200 are communicated through the heat medium pipeline.
As shown in fig. 8, the direction of the arrow in fig. 8 is a path through which the heating medium flows, the heating medium flows into the first heating medium chamber 430 through the heating medium inlet 130, the heating medium in the first heating medium chamber 430 flows into the second heating medium chamber 440 through the heating medium pipe penetrating the oxygenation chamber 200, heat exchange with the blood stream in the oxygenation chamber 200 is performed in the heating medium pipe, and the heating medium after heat exchange in the second heating medium chamber 440 flows out through the heating medium outlet 140.
Fig. 9 is a schematic view of an air cavity structure according to an embodiment of the present invention.
In an alternative embodiment, as shown in fig. 9, the housing 100 is provided with a gas inlet 150 on a sidewall thereof, and the gas inlet 150 is used for supplying an oxygen-containing gas into the gas chamber 500.
In an alternative embodiment, a gas outlet 160 is formed on a sidewall of the housing 100, and the gas outlet 160 is used for discharging the oxygen-containing gas after the reaction in the gas chamber 500.
In an alternative embodiment, a third partition 510 and a fourth partition 520 are provided in the air chamber 500, and the third partition 510 and the fourth partition 520 divide the air chamber 500 into a first air chamber 530 and a second air chamber 540.
In an alternative embodiment, the first air chamber 530 communicates with the air inlet 150 and the second air chamber 540 communicates with the air outlet 160.
In an alternative embodiment, the first air chamber 530 communicates with the second air chamber 540 via a gas line that passes through the oxygenation chamber 200.
In an alternative embodiment, the third partition 510 and the fourth partition 520 are respectively disposed at both ends of the blood outlet 120;
in an alternative embodiment, the third separator 510 and the fourth separator 520 divide the heating medium chamber 400 into the first air chamber 530 and the second air chamber 540 having the same size.
In an alternative embodiment, the gas inlet 150 is disposed on the side wall of the housing 100 at an end remote from the blood outlet 120.
In an alternative embodiment, the gas outlet 160 is disposed on the sidewall of the housing 100 near one end of the blood outlet 120.
In an alternative embodiment, the oxygenation chamber 200 is a quadrangular prism structure, and two opposite sides of the oxygenation chamber 200 are communicated through the gas pipeline.
As shown in fig. 9, the direction of the arrows in fig. 9 is a path for the circulation of gas, the gas enters the first gas chamber 530 through the gas inlet 150, the gas in the first gas chamber 530 enters the second gas chamber 540 through the gas line penetrating the oxygenation chamber 200, the gas line is ventilated with the blood flow in the oxygenation chamber 200, and the ventilated gas in the second gas chamber 540 is discharged through the gas outlet 160.
In another embodiment of the present invention, an extracorporeal membrane pulmonary oxygenation device is provided, which may include an oxygenator according to any one of the above technical solutions.
The invention provides an oxygenator and an extracorporeal membrane lung oxygenation device, wherein the oxygenator can comprise: the shell 100 is provided with an upper end cover 600 and a lower end cover 700 which are oppositely arranged, and the upper end cover 600 is connected with the lower end cover 700 through a side wall; a blood inlet 110 is arranged at the center of the upper end cover 600, and a blood outlet 120 is arranged at one end of the lower end cover 700 of the shell 100 close to the side wall; an oxygenation chamber 200 disposed within the housing 100, blood entering the oxygenation chamber 200 through the blood inlet 110, and oxygenated blood exiting through the blood outlet 120; a partition 300 disposed between the housing 100 and the oxygenation chamber 200, the partition 300 being disposed in the same direction as the upper cap 600, dividing the interior of the housing 100 into a heat medium chamber 400 and an air chamber 500. On the basis of multi-objective multi-parameter optimization research on hemodynamics, qi-blood exchange and the like, the oxygenator provided by the invention is combined with the design of the heat medium cavity 400 and the air cavity 500 to carry out brand new optimization design on the membrane lung blood flow channel, the air pipeline and the heat medium pipeline, so that the oxygenator is optimal in hemodynamics performance, uniform in internal flow field and pressure field distribution, small in flow retention area, low in blood flowing resistance, high in qi-blood exchange efficiency and heat exchange efficiency, and therefore the long-term support effect of the oxygenator is improved, the thrombus occurrence probability during long-term support is reduced, and the blood compatibility of the oxygenator is improved.
It is to be understood that the above-described embodiments of the present invention are merely illustrative of or explaining the principles of the invention and are not to be construed as limiting the invention. Therefore, any modification, equivalent replacement, improvement and the like made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. Further, it is intended that the appended claims cover all such variations and modifications as fall within the scope and boundary of the appended claims, or the equivalents of such scope and boundary.
Claims (10)
1. An oxygenator, comprising:
the shell (100) is provided with an upper end cover (600) and a lower end cover (700) which are oppositely arranged, and the upper end cover (600) is connected with the lower end cover (700) through a side wall; a blood inlet (110) is formed in the center of the upper end cover (600), and a blood outlet (120) is formed in one end, close to the side wall, of the lower end cover (700) of the shell (100);
an oxygenation chamber (200) disposed within the housing (100), blood entering the oxygenation chamber (200) through the blood inlet (110), oxygenated blood exiting through the blood outlet (120);
a partition (300) disposed between the housing (100) and the oxygenation chamber (200), the partition (300) being disposed in the same direction as the upper end cap (600), dividing the interior of the housing (100) into a heat medium chamber (400) and a gas chamber (500).
2. The oxygenator of claim 1,
be equipped with heat medium entry (130) and heat medium export (140) on the lateral wall of casing (100), heat medium passes through heat medium entry (130) gets into heat medium chamber (400), heat medium after the heat transfer passes through heat medium export (140) are discharged.
3. The oxygenator of claim 2,
the heating medium cavity (400) is also internally provided with a first separator (410) and a second separator (420), and the first separator (410) and the second separator (420) separate the heating medium cavity (400) into a first heating medium cavity (430) and a second heating medium cavity (440);
the first heating medium chamber (430) is communicated with the heating medium inlet (130), and the second heating medium chamber (440) is communicated with the heating medium outlet (140);
the first heating medium cavity (430) is communicated with the second heating medium cavity (440) through a heating medium pipeline, and the heating medium pipeline penetrates through the oxygenation chamber (200).
4. The oxygenator of claim 3,
the first partition (410) is disposed between the housing (100) and the oxygenation chamber (200) and near one end of the blood outlet (120);
the second isolation portion (420) is disposed between the housing (100) and the oxygenation chamber (200) and at an end remote from the blood outlet (120);
the first partition (410) and the second partition (420) divide the heat medium chamber (400) into the first heat medium chamber (430) and the second heat medium chamber (440) having the same size.
5. The oxygenator of claim 4,
the heat medium inlet (130) and the heat medium outlet (140) are disposed at one end of the sidewall of the case (100) near the blood outlet (120);
the oxygenation chamber (200) is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber (200) are communicated through the heat medium pipeline.
6. Oxygenator according to any of claims 1-5,
the side wall of the shell (100) is provided with a gas inlet (150) and a gas outlet (160), oxygen-containing gas enters the gas cavity (500) through the gas inlet (150), and gas after gas-blood exchange is discharged through the gas outlet (160).
7. The oxygenator of claim 6,
a third partition part (510) and a fourth partition part (520) are arranged in the air cavity (500), and the air cavity (500) is divided into a first air cavity (530) and a second air cavity (540) by the third partition part (510) and the fourth partition part (520);
the first air cavity (530) is communicated with the air inlet (150), and the second air cavity (540) is communicated with the air outlet (160);
the first air chamber (530) is communicated with the second air chamber (540) through an air line which passes through the oxygenation chamber (200).
8. The oxygenator of claim 7,
the third isolation part (510) and the fourth isolation part (520) are respectively arranged at two ends of the blood outlet (120);
the third partition (510) and the fourth partition (520) divide the heating medium chamber (400) into the first air chamber (530) and the second air chamber (540) having the same size.
9. The oxygenator of claim 8,
the gas inlet (150) is arranged at one end of the side wall of the shell (100) far away from the blood outlet (120);
the gas outlet (160) is arranged at one end of the side wall of the shell (100) close to the blood outlet (120);
the oxygenation chamber (200) is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber (200) are communicated through the gas pipeline.
10. An extracorporeal membrane lung oxygenation device comprising an oxygenator according to any one of claims 1 to 9.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
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| CN202210891858.6A CN115192807A (en) | 2022-07-27 | 2022-07-27 | Oxygenator and extracorporeal membrane lung oxygenating device |
| PCT/CN2023/108547 WO2024022236A1 (en) | 2022-07-27 | 2023-07-21 | Oxygenator and extracorporeal membrane lung oxygenation device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210891858.6A CN115192807A (en) | 2022-07-27 | 2022-07-27 | Oxygenator and extracorporeal membrane lung oxygenating device |
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| CN115192807A true CN115192807A (en) | 2022-10-18 |
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| CN202210891858.6A Pending CN115192807A (en) | 2022-07-27 | 2022-07-27 | Oxygenator and extracorporeal membrane lung oxygenating device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115607759A (en) * | 2022-10-31 | 2023-01-17 | 北京航空航天大学 | Blood oxygenator |
| WO2024022236A1 (en) * | 2022-07-27 | 2024-02-01 | 北京航天长峰股份有限公司 | Oxygenator and extracorporeal membrane lung oxygenation device |
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| WO2024022236A1 (en) * | 2022-07-27 | 2024-02-01 | 北京航天长峰股份有限公司 | Oxygenator and extracorporeal membrane lung oxygenation device |
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| CN115607759B (en) * | 2022-10-31 | 2023-04-28 | 北京航空航天大学 | Blood oxygenator |
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| WO2024022236A1 (en) | 2024-02-01 |
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