CN202393969U - Film producing clamp for liquid-based thin-layer cell - Google Patents
Film producing clamp for liquid-based thin-layer cell Download PDFInfo
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- CN202393969U CN202393969U CN2011205724887U CN201120572488U CN202393969U CN 202393969 U CN202393969 U CN 202393969U CN 2011205724887 U CN2011205724887 U CN 2011205724887U CN 201120572488 U CN201120572488 U CN 201120572488U CN 202393969 U CN202393969 U CN 202393969U
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- 239000007788 liquid Substances 0.000 title claims abstract description 18
- 239000011521 glass Substances 0.000 abstract description 21
- 210000004027 cell Anatomy 0.000 abstract description 15
- 238000004458 analytical method Methods 0.000 abstract description 4
- 238000003745 diagnosis Methods 0.000 abstract description 3
- 210000003743 erythrocyte Anatomy 0.000 abstract description 3
- 239000012535 impurity Substances 0.000 abstract description 3
- 210000003097 mucus Anatomy 0.000 abstract description 3
- 206010008342 Cervix carcinoma Diseases 0.000 description 4
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 4
- 201000010881 cervical cancer Diseases 0.000 description 4
- 101150038956 cup-4 gene Proteins 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000003761 preservation solution Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 238000003556 assay Methods 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
- Y02E60/10—Energy storage using batteries
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Abstract
本实用新型公开了一种液基薄层细胞制片夹，其包括扣合在一起的载玻片夹具盒体和载玻片夹具底板，载玻片固定在载玻片夹具盒体和载玻片夹具底板之间，载玻片夹具盒体中间对应载玻片位置设有开口，开口外垂直连接有导管，导管的另一端设有与导管垂直连通的筒状腔体，筒状腔体内设过滤杯，将放有采集标本的制片夹置于离心机中，当离心机高速运转后，经过过滤杯过滤后的脱落细胞在离心力的作用下，从筒状腔体经过导管及载玻片夹具盒体上的开口粘附到载玻片上，对于不能溶解且不能过滤的红细胞、粘液等杂质留在过滤杯内的过滤网上，采用本实用新型制片夹制成的液基标本上的脱落细胞分布均匀、背景干净，有利于病理学医生的观察分析和诊断，不易受干扰。
The utility model discloses a liquid-based thin-layer cell film-making clamp, which comprises a glass slide clamp box body and a glass slide clamp bottom plate fastened together, and the slide glass is fixed on the slide glass clamp box body and the glass slide clamp body. Between the bottom plates of the slide fixture, there is an opening corresponding to the position of the slide in the middle of the slide fixture box, a conduit is vertically connected outside the opening, and a cylindrical cavity vertically connected to the conduit is provided at the other end of the conduit. Filter cup, place the film-making clip with collected specimens in the centrifuge. When the centrifuge runs at high speed, the exfoliated cells filtered by the filter cup will pass through the catheter and glass slide from the cylindrical cavity under the action of centrifugal force. The opening on the fixture box adheres to the glass slide, and for impurities such as red blood cells and mucus that cannot be dissolved and filtered and remain on the filter net in the filter cup, the liquid-based specimens made of the utility model film-making clip will fall off. The cells are evenly distributed and the background is clean, which is conducive to the observation, analysis and diagnosis of pathologists, and is not susceptible to interference.
Description
技术领域 technical field
本实用新型涉及医疗生物化验技术领域，尤其涉及一种化验分析制片用的液基薄层细胞制片夹。The utility model relates to the technical field of medical biological assays, in particular to a liquid-based thin-layer cell slicer for assay analysis.
背景技术 Background technique
TCT主要是用于妇女宫颈癌的筛查，宫颈癌是女性各种恶性肿瘤病中最多的恶性肿瘤之一，而宫颈癌的病变是可早发现、早治疗、可治愈的一种疾病，特别是成年妇女定期进行妇科检查，可以不定期监测自己的健康状态，目前液基细胞的检测于2009年已列入“六项重大公共卫生服务项目”，特别是宫颈癌的检测已列入农村妇女常规检测项目。TCT is mainly used for the screening of cervical cancer in women. Cervical cancer is one of the most common malignant tumors in women. Cervical cancer is a disease that can be detected, treated and cured early, especially Adult women have regular gynecological examinations, and can monitor their health status from time to time. At present, liquid-based cell detection has been included in the "six major public health service items" in 2009, especially the detection of cervical cancer has been included in rural women Routine inspection items.
脱落细胞的筛查包括如下步骤：使用采样刷进采样、保存液保存、振荡溶解、液基薄层细胞制片、显微镜观察。现有的制片方法很多是由人工进行涂片制片的，在人工制作标本时载玻片上的脱落细胞难以涂布均匀，另外由于采样脱落细胞的标本中含有粘液、红细胞等杂质，致使标本涂片的背景不干净、清晰，从而影响病理学医生的观察分析和诊断。The screening of exfoliated cells includes the following steps: sampling with a sampling brush, storage in preservation solution, shaking and dissolving, liquid-based thin-layer cell sheet preparation, and microscope observation. Many of the existing film-making methods are manually smeared, and it is difficult to smear the exfoliated cells on the glass slide evenly when the specimen is artificially prepared. In addition, because the sample of the exfoliated cells contains impurities such as mucus and red blood cells, the specimens may be damaged. The background of the smear is not clean and clear, which affects the observation, analysis and diagnosis of pathologists.
发明内容 Contents of the invention
为克服现有技术的不足，本实用新型提供了一种操作方便、能够使制作的标本上的脱落细胞粘附均匀且不重叠、背景清晰的液基薄层细胞制片夹。In order to overcome the deficiencies of the prior art, the utility model provides a liquid-based thin-layer cell slide clip which is easy to operate, can make the exfoliated cells on the prepared specimen adhere uniformly without overlapping, and have a clear background.
本实用新型为达到上述技术目的所采用的技术方案是：一种液基薄层细胞制片夹，其包括载玻片夹具盒体和载玻片夹具底板，载玻片夹具盒体扣合在载玻片夹具底板上，载玻片固定在载玻片夹具盒体和载玻片夹具底板之间，载玻片夹具盒体中间对应载玻片位置设有开口，开口外垂直连接有导管，导管的另一端设有与导管垂直连通的筒状腔体，筒状腔体内设过滤杯；从过滤杯过滤出的液体能够从筒状腔体经过导管及载玻片夹具盒体上的开口涂覆到载玻片上。The technical scheme adopted by the utility model to achieve the above technical purpose is: a liquid-based thin-layer cell film-making clamp, which includes a slide clamp box body and a slide slide clamp bottom plate, and the slide slide clamp box body is fastened on the On the bottom plate of the slide holder, the slide is fixed between the slide holder box body and the slide holder bottom plate, an opening is provided in the middle of the slide holder box corresponding to the position of the slide, and a conduit is vertically connected outside the opening, The other end of the conduit is provided with a cylindrical cavity vertically connected with the conduit, and a filter cup is arranged in the cylindrical cavity; the liquid filtered from the filter cup can be sprayed from the cylindrical cavity through the conduit and the opening on the slide holder box. onto a glass slide.
载玻片夹具底板上设有固定载玻片的定位台阶和压紧载玻片的拱形弹片。The bottom plate of the slide fixture is provided with a positioning step for fixing the slide and an arched shrapnel for pressing the slide.
所述载玻片夹具盒体和载玻片夹具底板上一侧对应设有圆弧形开口，方便取拿载玻片。The box body of the slide glass holder and one side of the bottom plate of the slide glass holder are correspondingly provided with an arc-shaped opening, which is convenient for taking the slide glass.
所述过滤杯的杯底设有可更换的过滤网。The bottom of the filter cup is provided with a replaceable filter screen.
所述过滤杯为口大底小的锥形。The filter cup is conical with a large mouth and a small bottom.
本实用新型的有益效果是：采用上述结构，采集的细胞样本经过保存液溶解保存后置于上述制片夹的过滤杯中，再将装有载玻片的液基薄层细胞制片夹置于离心机中，当离心机高速运转后，经过过滤杯滤后的液基在离心力的作用下，从筒状腔体经过导管及载玻片夹具盒体上的开口涂覆到载玻片上，对于不能溶解且不能过滤的红细胞、粘液等杂质留在过滤杯内的过滤网上，采用本实用新型制片夹制成的液基标本上的脱落细胞分布均匀、背景干净，有利于病理学医生的观察分析和诊断，不易受干扰。The beneficial effects of the utility model are: adopting the above structure, the collected cell samples are placed in the filter cup of the above-mentioned film-making clip after being dissolved and stored in the preservation solution, and then the liquid-based thin-layer cell film-making with glass slides is clamped In the centrifuge, when the centrifuge runs at high speed, the liquid base filtered by the filter cup is coated on the glass slide from the cylindrical cavity through the opening of the catheter and the glass slide holder box under the action of centrifugal force. For impurities such as red blood cells and mucus that cannot be dissolved and cannot be filtered remain on the filter screen in the filter cup, the exfoliated cells on the liquid-based specimen made by the utility model are evenly distributed and the background is clean, which is beneficial to pathology doctors. Observation analysis and diagnosis, less susceptible to interference.
附图说明 Description of drawings
下面结合附图和实施例对本实用新型作进一步说明。其中：Below in conjunction with accompanying drawing and embodiment the utility model is further described. in:
图1是本实用新型制片夹的剖视结构示意图：Fig. 1 is the sectional structure schematic diagram of the utility model film-making folder:
图2是本实用新型制片夹的立体分解示意图。Fig. 2 is a three-dimensional exploded schematic view of the film-making clip of the present invention.
具体实施方式 Detailed ways
为详细说明本实用新型的技术内容、构造特征、所实现目的及效果，以下结合实施方式并配合附图详予说明。In order to describe the technical content, structural features, achieved goals and effects of the present utility model in detail, the following will be described in detail in conjunction with the embodiments and accompanying drawings.
请参阅图1以及图2所示，本实用新型制片夹包括载玻片夹具盒体1和载玻片夹具底板2，载玻片夹具盒体1扣合在载玻片夹具底板2上，载玻片3固定在载玻片夹具盒体1和载玻片夹具底板2之间，载玻片夹具盒体1中间对应载玻片3位置设有开口11，开口11外垂直连接有导管12，导管12的另一端设有与导管12垂直连通的筒状腔体13，筒状腔体13内设过滤杯4；从过滤杯4过滤出的液体能够从筒状腔体13经过导管12及载玻片夹具盒体1上的开口11涂覆到载玻片3上。Please refer to Fig. 1 and Fig. 2, the utility model film-making clamp includes a slide
载玻片夹具底板2上设有固定载玻片3的定位台阶21和压紧载玻片3的拱形弹片22。The
所述载玻片夹具盒体1和载玻片夹具底板2上一侧对应设有圆弧形开口14、23，方便取拿载玻片3。Arc-
所述过滤杯4的杯底设有可更换的过滤网5。A
所述过滤杯4为口大底小的锥形。The
所述载玻片夹具盒体1和载玻片夹具底板2为塑料注塑加工而成。The slide glass
以上所述仅为本实用新型的实施例，并非因此限制本实用新型的专利范围，凡是利用本实用新型说明书及附图内容所作的等效结构变换，或直接或间接运用在其他相关的技术领域，均同理包括在本实用新型的专利保护范围内。The above descriptions are only embodiments of the present utility model, and are not intended to limit the patent scope of the present utility model. All equivalent structural transformations made by using the description of the utility model and the contents of the accompanying drawings are directly or indirectly used in other related technical fields. , are all included in the scope of patent protection of the utility model in the same way.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205724887U CN202393969U (en) | 2011-12-31 | 2011-12-31 | Film producing clamp for liquid-based thin-layer cell |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205724887U CN202393969U (en) | 2011-12-31 | 2011-12-31 | Film producing clamp for liquid-based thin-layer cell |
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| CN202393969U true CN202393969U (en) | 2012-08-22 |
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| CN2011205724887U Expired - Fee Related CN202393969U (en) | 2011-12-31 | 2011-12-31 | Film producing clamp for liquid-based thin-layer cell |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106769352A (en) * | 2016-11-28 | 2017-05-31 | 广州江元医疗科技有限公司 | A kind of fixture for Cell sheet glass dyeing |
| CN107923821A (en) * | 2015-09-14 | 2018-04-17 | 国立大学法人滋贺医科大学 | Cell holding substrate holder for making observation specimen, kit including the same, and method for making observation specimen |
| CN108956218A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Centrifugal Thinprep pap test pelleter is pressed from both sides with film-making |
| CN108956219A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Thinprep pap test pelleter is pressed from both sides with film-making |
| CN110631877A (en) * | 2019-10-28 | 2019-12-31 | 宁波美生医疗器材有限公司 | Tripping and separating mechanism for liquid-based cell film production |
| CN112098177A (en) * | 2020-10-09 | 2020-12-18 | 兴宏业（武汉）科技有限公司 | A centrifugal tableting chamber |
| CN116558920A (en) * | 2023-05-11 | 2023-08-08 | 深圳市森盈生物科技有限公司 | A kind of liquid-based thin-layer tablet-making equipment and tablet-making method |
-
2011
- 2011-12-31 CN CN2011205724887U patent/CN202393969U/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107923821A (en) * | 2015-09-14 | 2018-04-17 | 国立大学法人滋贺医科大学 | Cell holding substrate holder for making observation specimen, kit including the same, and method for making observation specimen |
| US10890513B2 (en) | 2015-09-14 | 2021-01-12 | National University Corporation Shiga University Of Medical Science | Cell-holding substrate holder for preparing observation specimen, kit including same, and observation specimen preparation method |
| CN106769352A (en) * | 2016-11-28 | 2017-05-31 | 广州江元医疗科技有限公司 | A kind of fixture for Cell sheet glass dyeing |
| CN108956218A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Centrifugal Thinprep pap test pelleter is pressed from both sides with film-making |
| CN108956219A (en) * | 2017-05-23 | 2018-12-07 | 北京诚智光辉科技有限公司 | Thinprep pap test pelleter is pressed from both sides with film-making |
| CN108956218B (en) * | 2017-05-23 | 2021-02-19 | 北京诚智光辉科技有限公司 | Slice making clamp for centrifugal liquid-based thin-layer cell slice making machine |
| CN108956219B (en) * | 2017-05-23 | 2021-02-19 | 北京诚智光辉科技有限公司 | Film making clamp for liquid-based thin-layer cell film making machine |
| CN110631877A (en) * | 2019-10-28 | 2019-12-31 | 宁波美生医疗器材有限公司 | Tripping and separating mechanism for liquid-based cell film production |
| CN112098177A (en) * | 2020-10-09 | 2020-12-18 | 兴宏业（武汉）科技有限公司 | A centrifugal tableting chamber |
| CN116558920A (en) * | 2023-05-11 | 2023-08-08 | 深圳市森盈生物科技有限公司 | A kind of liquid-based thin-layer tablet-making equipment and tablet-making method |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120822 Termination date: 20141231 |
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| EXPY | Termination of patent right or utility model |