CN201560188U - Full smoke exposure device of cigarette - Google Patents
Full smoke exposure device of cigarette Download PDFInfo
- Publication number
- CN201560188U CN201560188U CN2009202235171U CN200920223517U CN201560188U CN 201560188 U CN201560188 U CN 201560188U CN 2009202235171 U CN2009202235171 U CN 2009202235171U CN 200920223517 U CN200920223517 U CN 200920223517U CN 201560188 U CN201560188 U CN 201560188U
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- exposure chamber
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- fume exposure
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- fume
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Abstract
A full smoke exposure device of cigarette is characterized in that the device comprises a smoke diluting unit, a smoke exposure chamber and a water-bath constant-temperature heating tank for heating the smoke exposure chamber, wherein one end of the smoke diluting unit is connected with a smoking machine, and the other end is connected with the smoke inlet at the top part of the smoke exposure chamber; the smoke exposure chamber has an upper open cover; the smoke inlet is formed at the center on the top of the cover; a stand for fixing and placing a culturing tool is arranged in the smoke exposure chamber; and the smoke exposure chamber is hung in the water-bath constant-temperature heating tank and can be controlled by a sway control mechanism to sway. The full smoke exposure device can accurately control the smoke dilution concentration to ensure the continuous renewing of the smoke in the exposure chamber, and has the advantages of simple structure, easy manufacture and convenient operation. The full smoke exposure device can be directly connected with the smoking machine to construct a full smoke exposure test system for achieving full smoke exposure to cells cultured in vitro, thereby comprehensively and authentically reflecting the biological effect of the smoke.
Description
Technical field
The utility model relates to the external toxicological evaluation research field of cigarette mainstream flue gas, is a kind of device that is used for the full fume exposure contamination of cigarette specifically.
Background technology
The external toxicologic study of cigarette smoke has become estimates smoking to one of important means of Health hazard.At present, the device that is used for full fume exposure experiment is few, in existing bibliographical information, the CULTEX exposure system is a kind of fume exposure device that comparatively adopts in the world, each cell cultures cell of this device all has a cover gas separately and imports and exports the pipeline that exchanges with nutrient solution, but its complex structure, cost is higher; Do not have the flue gas dilution device.Domestic patent (ZL 200720092154.3) is a kind of device that external toxicology main flume exposes that is used for, it is characterized in that: comprise gas-tight silo and the control unit that is used to control condition in the storehouse, in gas-tight silo, be provided with the anchor that is used to place Tissue Culture Flask.The advantage of this device is simple in structure, is easy to make, and tentatively can realize the exposure experiment contamination of cigarette mainstream flue gas.But it has the following disadvantages: do not have the flue gas dilution device, can't carry out the exposure experiment of different flue gas concentrations etc.
Summary of the invention
The purpose of this utility model provides the full fume exposure contamination device of a kind of cigarette, has the flue gas dilution function, can directly be connected with smoking machine, and realization is flue toxicity contaminated entirely to cultured cell in vitro, reflects the biological effect of flue gas truly more comprehensively.
The purpose of this utility model is achieved through the following technical solutions: the full fume exposure contamination device of cigarette of the present utility model, comprise the flue gas dilution unit, fume exposure chamber and the constant temperature water bath heating tank that is used for the water-bath of fume exposure chamber, described flue gas dilution unit is made up of flue gas suction piston and two-bit triplet magnetic valve, this unit one end is connected with smoking machine, and the other end is connected to the inlet mouth at top, fume exposure chamber; Described fume exposure chamber is last open type, center of top at lid is a smoke air inlet, inlet mouth bottom is provided with discoid mesh-type air inlet port, and fume exposure chamber sidewall is provided with venting hole, and fume exposure is indoor to be provided with one and to be used for fixing and to place the support of cultivating apparatus; The suspension of fume exposure chamber places in the constant temperature water bath heating tank and can regulate swing by oscillating control mechanism.
Support set in the exposure chamber is two-layer and adjustable height, and the cultivation apparatus that is placed on the support can be culturing bottle, culture dish or microwell plate etc.
The fume exposure chamber is by the exposure chamber gripper frame and be fixed on fixedly hanger suspending on the gripper frame in the constant temperature water bath heating tank, and can regulate swing by oscillating control mechanism, oscillating control mechanism is installed in fixedly on the suspension bracket, comprises that motor, turbine, transmission worm screw form.By driven by motor turbine and worm mechanism, turbine and exposure chamber gripper frame are fixed together, and angle of turbine rotation drives the same angle of fume exposure chamber rotation simultaneously.The hunting frequency that can set the fume exposure chamber and swing inclination angle can make cell partly be exposed to cultivate liquid level and contact with flue gas to reach.
Described constant temperature water bath heating tank has temperature conditioning unit, and temperature conditioning unit is made up of temperature monitoring probe and electronic heating element.
Principle of work of the present utility model and process are: can send flue gas to the fume exposure chamber with different Dilution ratios by smoking machine with flue gas suction piston, flue gas evenly enters in the exposure chamber by the inlet mouth on the exposure chamber top cover in the spray mode, the cells in vitro that realization is opposite in the cultivation apparatus on the support is flue toxicity contaminated, also can make the indoor cell of fume exposure partly to be exposed to cultivate liquid level and directly contacts with flue gas by oscillating control mechanism.
The advantage of this experimental installation is:
1. characteristics such as the utlity model has and can accurately control flue gas dilution concentration, the continuous renewal of flue gas is simple in structure in the assurance exposure chamber, is easy to make, and is easy and simple to handle.
2. this utility model can directly be connected the experimental system that can set up full fume exposure with smoking machine, and realization is flue toxicity contaminated entirely to cultured cell in vitro, can reflect the biological effect of flue gas truly more comprehensively.
Description of drawings
Fig. 1 is an one-piece construction synoptic diagram of the present utility model.
Fig. 2 is flue gas dilution unit and exposure chamber loam cake connection diagram.
Fig. 3 is the supporting structure synoptic diagram.
Fig. 4 is a fume exposure cell structure view.
Fig. 5 is a fume exposure chamber oscillating control mechanism.
Fig. 6 is the left view of Fig. 5.
Fig. 7 is arranged in the synoptic diagram of constant temperature water bath heating tank for the fume exposure chamber.
Among the figure: 1, cigarette props up; 2, hold the cigarette device; 3, flue gas suction piston; 4, two-bit triplet magnetic valve (air); 5, two-bit triplet magnetic valve (flue gas); 6, inlet mouth (spray-type); 7, exposure chamber top cover; 8, support; 9, venting hole; 10, fume exposure chamber; 11, motor; 12, worm gear; 13, transmission worm screw; 14 backs are suspension bracket fixedly; 15, fume exposure chamber gripper frame; 16, preceding fixedly suspension bracket; 17 electric machine supports; 18, drive shaft; 19, back shaft; 20, in the constant temperature water bath heating tank.
Embodiment
The utility model is described further below in conjunction with accompanying drawing.
Shown in Fig. 1-7: the full fume exposure contamination device of cigarette of the present utility model, comprise the flue gas dilution unit, fume exposure chamber and the constant temperature water bath heating tank that is used for the water-bath of fume exposure chamber, described flue gas dilution unit is made up of flue gas suction piston 3 and two-bit triplet magnetic valve 4,5, this unit one end is connected with smoking machine, and the other end is connected to the inlet mouth 6 of fume exposure chamber top cover 7; Described fume exposure chamber is last open type, center of top at lid is a smoke air inlet 6, inlet mouth bottom is provided with discoid mesh-type air inlet port, and fume exposure chamber sidewall is provided with venting hole 9, and fume exposure is indoor to be provided with one and to be used for fixing and to place the two-layer travel(l)ing rest 8 of cultivating apparatus; Fume exposure chamber 10 by exposure chamber gripper frame 15 and be fixed on the gripper frame front and back fixedly suspension bracket 14,16 be suspended in the constant temperature water bath heating tank 20, and can regulate swing by oscillating control mechanism, oscillating control mechanism is installed in fixedly on the suspension bracket, comprise motor 11, turbine 12, transmission worm screw 13 compositions, drive turbine 12 and transmission worm screw 13 by motor 11, turbine 12 is fixed together with exposure chamber gripper frame 15, turbine 12 rotates an angle, drives the same angle of fume exposure chamber 10 rotations simultaneously.
When carrying out the full fume exposure exposure experiment of cigarette, at first regulate the design temperature of constant temperature water bath heating tank, make the indoor envrionment temperature pre-equilibration to 37 of fume exposure ℃.Open the top cover of fume exposure chamber, Tissue Culture Flask or culture dish or microwell plate are fixed on the travel(l)ing rest 8, close top cover 7, obtain suitable hunting frequency and swing inclination angle, make cell can partly expose the cultivation liquid level and contact with flue gas by regulating oscillating control mechanism.Opening two-bit triplet magnetic valve (flue gas) 5 is drawn into the main flume of smoking machine suction in the inflator of flue gas suction piston 3, close 5 subsequently, opening two-bit triplet magnetic valve (air) 4 is drawn into fresh air in 3 the inflator, by being set, parameters such as 3 step distance and to-and-fro movement number of times make flue gas and air carry out thorough mixing to reach target flue gas dilution concentration, subsequently the flue gas of dilution is discharged, it is indoor to enter into fume exposure by the air inlet port on the top cover of fume exposure chamber in the mode that sprays, thereby makes cellular exposure in the flue gas environment.
Claims (5)
1. full fume exposure contamination device of cigarette, it is characterized in that: comprise the flue gas dilution unit, fume exposure chamber and the constant temperature water bath heating tank that is used for the water-bath of fume exposure chamber, described flue gas dilution unit is made up of flue gas suction piston and two-bit triplet magnetic valve, this unit one end is connected with smoking machine, and the other end is connected to the inlet mouth at top, fume exposure chamber; Described fume exposure chamber is last open type, center of top at lid is a smoke air inlet, inlet mouth bottom is provided with discoid mesh-type air inlet port, and fume exposure chamber sidewall is provided with venting hole, and fume exposure is indoor to be provided with one and to be used for fixing and to place the support of cultivating apparatus; The suspension of fume exposure chamber places in the constant temperature water bath heating tank and can regulate swing by oscillating control mechanism.
2. the full fume exposure contamination device of cigarette according to claim 1 is characterized in that: described support is two-layer and adjustable height.
3. the full fume exposure contamination device of cigarette according to claim 1 is characterized in that: the fume exposure chamber is by the exposure chamber gripper frame and be fixed on fixedly hanger suspending on the gripper frame in the constant temperature water bath heating tank.
4. the full fume exposure contamination device of cigarette according to claim 1, it is characterized in that: oscillating control mechanism is installed in fixedly on the suspension bracket, comprise motor, turbine, transmission worm screw composition, by driven by motor turbine and worm mechanism, turbine and exposure chamber gripper frame are fixed together, angle of turbine rotation drives the same angle of fume exposure chamber rotation simultaneously.
5. the full fume exposure contamination device of cigarette according to claim 1 is characterized in that: the cultivation apparatus is culturing bottle, culture dish or microwell plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202235171U CN201560188U (en) | 2009-09-17 | 2009-09-17 | Full smoke exposure device of cigarette |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202235171U CN201560188U (en) | 2009-09-17 | 2009-09-17 | Full smoke exposure device of cigarette |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201560188U true CN201560188U (en) | 2010-08-25 |
Family
ID=42625335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009202235171U Expired - Lifetime CN201560188U (en) | 2009-09-17 | 2009-09-17 | Full smoke exposure device of cigarette |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201560188U (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102010818A (en) * | 2010-10-28 | 2011-04-13 | 天津开发区合普工贸有限公司 | Control device of cell exposing gas with controllable concentration |
| CN102093953A (en) * | 2010-11-26 | 2011-06-15 | 天津开发区合普工贸有限公司 | Device for cell contaminated dust exposure test |
| CN102206572A (en) * | 2011-03-11 | 2011-10-05 | 云南烟草科学研究院 | Device for exposing cigarette mainstream smoke |
| CN102419272A (en) * | 2011-08-17 | 2012-04-18 | 上海烟草集团有限责任公司 | Particle size grading acquisition method of cigarette mainstream smoke aerosol |
| WO2013064466A1 (en) * | 2011-10-31 | 2013-05-10 | British American Tobacco (Investments) Limited | Fluid distribution in a sample exposure device |
| CN105486852A (en) * | 2016-02-16 | 2016-04-13 | 苏州大学 | Contamination experimental facility |
-
2009
- 2009-09-17 CN CN2009202235171U patent/CN201560188U/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102010818A (en) * | 2010-10-28 | 2011-04-13 | 天津开发区合普工贸有限公司 | Control device of cell exposing gas with controllable concentration |
| CN102093953A (en) * | 2010-11-26 | 2011-06-15 | 天津开发区合普工贸有限公司 | Device for cell contaminated dust exposure test |
| CN102206572A (en) * | 2011-03-11 | 2011-10-05 | 云南烟草科学研究院 | Device for exposing cigarette mainstream smoke |
| CN102419272A (en) * | 2011-08-17 | 2012-04-18 | 上海烟草集团有限责任公司 | Particle size grading acquisition method of cigarette mainstream smoke aerosol |
| CN102419272B (en) * | 2011-08-17 | 2013-11-20 | 上海烟草集团有限责任公司 | Particle size grading acquisition method of cigarette mainstream smoke aerosol |
| WO2013064466A1 (en) * | 2011-10-31 | 2013-05-10 | British American Tobacco (Investments) Limited | Fluid distribution in a sample exposure device |
| US9598666B2 (en) | 2011-10-31 | 2017-03-21 | British American Tobacco (Investments) Limited | Fluid distribution in a sample exposure device |
| CN105486852A (en) * | 2016-02-16 | 2016-04-13 | 苏州大学 | Contamination experimental facility |
| CN105486852B (en) * | 2016-02-16 | 2017-08-25 | 苏州大学 | Exposure experimental device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20100825 |