CN201379989Y - Chromatographic column assembly - Google Patents
Chromatographic column assembly Download PDFInfo
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- CN201379989Y CN201379989Y CN200920000139U CN200920000139U CN201379989Y CN 201379989 Y CN201379989 Y CN 201379989Y CN 200920000139 U CN200920000139 U CN 200920000139U CN 200920000139 U CN200920000139 U CN 200920000139U CN 201379989 Y CN201379989 Y CN 201379989Y
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- chromatographic column
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Abstract
The utility model discloses a chromatographic column assembly particularly suitable for separating and purifying Chinese herbal medicine, natural products, biological products and other active ingredients, which comprises a column head, a sealing piece, a screen and a column body, wherein the column body is of a cylindrical hollow tubular column, and external threads are formed on the outer walls of the two ends of the column body; the column head is shaped as a cap, and internal threads matched with the external threads of the column body are formed on the inner wall of the column head; a through hole is formed at the top of the column head, and the sealing piece and the screen are formed in the column head and plays the roles of sealing and filtering; and a through hole is formed on the sealing piece corresponding to the through hole of the column head. The utility model has simple structure, good sealing performance, easy operation; convenient filler loading, convenient disassembly, good separation effect, high column efficiency, wide application range and long service life.
Description
Technical field
The utility model relates to a kind of chromatographic column, particularly is applicable to the medium pressure chromatography post of Chinese herbal medicine, natural products, biological products isoreactivity component separation purifying.
Background technology
Chromatographic column is a kind of common chemical, biology, pharmaceutical test chamber equipment.Chromatographic column is with a wide range of applications in Chinese herbal medicine, natural products, biological products isoreactivity component separation purifying.Common chromatographic column is normal pressure or low pressure chromatographic column, is made up of cylinder, column cap, seal, screen cloth etc. usually.At present, simple in structure, low-cost chromatographic column is organic solvent-resistant not such as column cap, seal often, and sealing neither be fine, and the phenomenon of leakage can take place, and causes its range of application very limited.Therefore should not be used for the separation and purification of natural products, Chinese herbal medicine active component.Indivedual chromatographic columns can tolerate organic solvent, can be applicable to natural products, Chinese herbal medicine effective ingredients separation and purification, but its tolerance range are also very limited; And the packing into and the disassembling section complexity, can not carry out the filling of disposable filler of high, the complex structure of price, filler often, it is not high to cause post to be imitated, and finally can not extensively satisfy the requirement of active ingredient separation and purification such as natural products, Chinese herbal medicine.Problem such as ask 01244876.1 in the Chinese utility model of " Separation of Natural Products purifying chromatographic column " for example by name, all there is complex structure in the disclosed chromatographic columns such as Chinese utility model application 200520121983.0 of " a kind of novel in press separate chromatographic column " by name, operation inconvenience, post effect are not high.
The utility model content
In view of above-mentioned deficiency of the prior art, the utility model provides a kind of chromatographic column assembly that is widely used in Chinese herbal medicine, natural products, biological products isoreactivity component separation purifying with low cost, simple in structure, easy to operate, applied widely.
In order to solve the problems of the technologies described above, a technical scheme of the present utility model provides a kind of chromatographic column assembly, comprises column cap, seal, screen cloth, cylinder, and wherein: cylinder is a cylindric hollow column jacket, is formed with external screw thread at two end outer wall; The column cap profile is the cap shape, and its inwall is formed with the internal thread that matches with the external screw thread of cylinder, and the column cap top is formed with through hole; Seal and screen cloth are shaped as and can place the effect of playing sealing within the column cap and filtering; And seal is being formed with through hole with the corresponding position of the through hole of column cap.
The material of cylinder is glass normally, is preferably quartz glass or high-boron-silicon glass.The material of seal is generally fluorine resin, for example polytetrafluoroethylene (PTFE).Screen cloth is made by resistant material usually, is for example made by stainless steel, for example the 316L stainless steel.The material of column cap is metal or plastics normally, for example engineering plastics, for example polyformaldehyde.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described seal is directly placed within the column cap to cooperate with the inwall of column cap to play sealing function; And described seal is formed with a cavity, and described screen cloth is placed within the described cavity.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described seal and screen cloth are directly placed within the column cap separately.Preferably, when column cap was connected with cylinder, screen cloth was placed between seal and the cylinder top.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described seal and screen cloth are placed in the upper position place (i.e. the position at close column cap top) within the column cap.
In the chromatographic column assembly that another technical scheme of the present utility model provides, at least two in described column cap, seal and the screen cloth are combined into one.For example, column cap and seal are combined into one, and perhaps seal and screen cloth are combined into one, and perhaps column cap, seal and screen cloth all are combined into one.
In the chromatographic column assembly that another technical scheme of the present utility model provides, the thread turns of described external screw thread and internal thread is 4.5.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described chromatographic column assembly also comprises connector, sealing ring and auxiliary tubing string, and wherein: auxiliary tubing string is a cylindric hollow column jacket, is formed with external screw thread at its at least one end outer wall; Connector is a round buss, and its inwall is formed with the internal thread that cooperates respectively with cylinder external screw thread and auxiliary tubing string external screw thread; Sealing ring is an annular shim, is placed in when cylinder is connected by connector with auxiliary tubing string between cylinder and the auxiliary tubing string.The material of auxiliary tubing string is glass normally, is preferably quartz glass or high-boron-silicon glass, and is identical with cylinder usually.The material of connector is metal or plastics normally, and for example polyformaldehyde is identical with column cap usually.The material of sealing ring is generally fluorine resin, and for example polytetrafluoroethylene (PTFE) is identical with seal usually.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described auxiliary tubing string is identical with the cylinder caliber.
In the chromatographic column assembly that another technical scheme of the present utility model provides, two end outer walls of described auxiliary tubing string all are formed with external screw thread, and thread turns is 4.5.
In the chromatographic column assembly that another technical scheme of the present utility model provides, described chromatographic column assembly also comprises the plug that matches with the top through hole of column cap.
Another technical scheme of the present utility model provides a kind of chromatographic column assembly, comprises column cap, seal, screen cloth, cylinder, and wherein: cylinder is a cylindric hollow column jacket, is formed with external screw thread at two end outer wall; The column cap profile is the cap shape, and its top is formed with through hole, and its inwall is formed with the internal thread that matches with the external screw thread of cylinder, and described column cap is connected in cylinder two ends up and down by described internal and external screw thread; Described seal and screen cloth are placed within the described column cap, between the top and described cylinder top of described column cap; Seal is being formed with through hole with the corresponding position of the through hole of column cap.
The technical characterictic of mentioning can make up arbitrarily each other in each different technologies scheme of the present utility model, and these make up all within scope of the present utility model.
The utility model can reach following one or more effect:
1. the chromatographic column modular construction according to a technical scheme of the present utility model is simple, and good airproof performance is easy to operate, and maintenance clean is convenient.
2. the chromatographic column assembly according to a technical scheme of the present utility model can change traditional filler type of feed, can conveniently carry out disposable filler filling, and is for convenience detach.
3. can withstand voltage 1MPa according to the chromatographic column assembly of a technical scheme of the present utility model, can guarantee the flow velocity of chromatography process stabilization by the control of pressure, reach chromatography effect preferably.By regulating pressure, adjust the flow velocity of chromatography process, reduce the spent time in the chromatography process, increase the separation and purification treatment amount.
4. the chromatographic column assembly according to a technical scheme of the present utility model can tolerate all organic solvents, and the chromatography process can be selected elution requirement widely, makes the sample separation better effects if, and the scope of application is wider.Especially active ingredient is separated in Chinese herbal medicine, natural products, the zymotic fluid.
5. the chromatographic column assembly according to a technical scheme of the present utility model can repeated multiple times use, and increases the service life, and reduces waste of material, and is cheap.
Description of drawings
Fig. 1 is the assembled state schematic diagram according to the medium pressure chromatography column assembly 100 of a technical scheme of the present utility model.
Fig. 2 is the end decomposing schematic representation of chromatographic column assembly 100 shown in Figure 1.
Fig. 3 is the schematic structure cutaway view in the end of chromatographic column assembly 100 shown in Figure 1 (amplification).
Fig. 4 is according to the schematic structure cutaway view in the end of the chromatographic column assembly 200 of another technical scheme of the utility model (amplification)
Fig. 5 is the assembled state schematic diagram according to the chromatographic column assembly 300 of another technical scheme of the utility model.
Fig. 6 is the decomposing schematic representation of chromatographic column assembly 300 shown in Figure 5.
Fig. 7 is the amplification view of element 5 in the chromatographic column assembly 300 shown in Figure 5.
Fig. 8 is the amplification plan view of element 6 in the chromatographic column assembly 300 shown in Figure 5.
The specific embodiment
For the ease of understanding the utility model better, some embodiment of the present utility model will be described below.But should be realized that, these embodiment just can embody the concrete example of the utility model spirit, it is exemplary but not exhaustive, and those skilled in the art is under the instruction of these embodiment, be easy to the following specific embodiment that provides is made alternative, distortion and improved, so the utility model is not limited to following specific embodiment.In addition, in explanation and describing, some known structure, parts, feature, method are not elaborated, have obscured the utility model in order to avoid a presumptuous guest usurps the role of the host.In the accompanying drawings, unless specialize, identical or similar label is represented identical or similar parts or step.For the details of parts is shown, accompanying drawing is not that strictness is drawn in proportion.
Fig. 1 is the assembled state schematic diagram according to the medium pressure chromatography column assembly 100 of a technical scheme of the present utility model.It will be understood by those skilled in the art that chromatographic column assembly of the present utility model comprises a plurality of elements, they both can fit together, and also can resolve into independently element.Fig. 2 is the decomposing schematic representation of an end of chromatographic column assembly 100.Fig. 3 is 100 1 schematic amplification views in end of chromatographic column assembly.In the present embodiment, two end constructions of chromatographic column assembly 100 are identical, so only show an end construction among Fig. 2, Fig. 3.The structure of two ends that it will be understood by those skilled in the art that the chromatographic column assembly is normally identical, but the utility model is not limited to this, also can adopt the slightly different chromatographic column of end construction as required.
From Fig. 1, Fig. 2, Fig. 3 as can be seen, chromatographic column assembly 100 comprises column cap 1, seal 2, screen cloth 3, cylinder 4.
In present embodiment (Fig. 3), screen cloth 3 directly embeds seal 2, and seal 2 directly embeds within the column cap 1 again.But the utility model is not limited thereto.For example,, have identical external diameter with seal 2, all approximate the internal diameter of column cap 1, and directly embed within the column cap 1 separately according to the screen cloth 3 of the chromatographic column assembly 200 of another technical scheme of the utility model referring to Fig. 4.In addition, those skilled in the art can also adjust and revise the profile and the structure of seal 2, screen cloth 3 as required, as long as they can be combined together with column cap 1, the effect of playing sealing and filtration gets final product.For example, column cap 1 inwall can all form internal thread, and seal 2 outer walls form external screw thread, and seal 2 also is connected with column cap 1 by screw thread.
In the chromatographic column assembly 100 of present embodiment, screen cloth 3, seal 2, column cap 1 are formed an integral body and offer the user.The product that promptly offers the user has only column cap 1 and cylinder 4 from apparent, and screen cloth 3, seal 2 have embedded in process within the column cap 1.Like this, when the actual user uses, only need simply column cap 1 to be tightened on the cylinder 4, just can realize sealing, be used for the chromatography experiment.But the utility model is not limited to this, it will be understood by those skilled in the art that one of them or two or three element of screen cloth 3, seal 2, column cap 1 can independently provide.For example, in chromatographic column assembly 200 shown in Figure 4, column cap 1 and seal 2 can be integrated in together, and screen cloth 3 independently provides.Need when the user operates so earlier screen cloth 3 to be put into column cap 1, again column cap 1 is installed to cylinder 4.Perhaps, also can seal 2, screen cloth 3 integrates, and only column cap 1 provides separately.Even screen cloth 3, seal 2, column cap 1 all independently provide.These several modes of back have been sacrificed the convenience of experimental implementation slightly, but are convenient to the replacing or the cleaning of seal 2 or screen cloth 3 (especially screen cloth 3).
Because screen cloth 3, seal 2, column cap 1 both can independently provide, can integrate again, in operating process, column cap 1 links together sometimes with cylinder 4 in addition, sometimes separate, so this relative position relation of several is dynamic, variation in the assembly of the present utility model.So, in the utility model, parts " are placed " when mentioning, in " embedding " another parts the time, perhaps when parts are " connected " another parts, not representing to limit these two parts must combine, but only represents the relative position relation when each parts assembling.
In addition, alternatively, chromatographic column assembly 100 or 200 can also comprise two plug (not shown)s, is used for sealing when needed the through hole 10 of column cap 1.For this purpose, can be in through hole 10 machining internal thread, and threading on the plug, both interconnect whereby.Perhaps, through hole 10 can be not threaded, plug make by slightly flexible material and also its slightly larger in diameter in through hole 10, realize whereby closely cooperating.
In addition, when the inventor found that the thread turns of column cap 1, cylinder 4 is 4.5 circles, effect was good especially, can realize the well balanced of ease of processing and sealing.
With an end of column cap 1 (containing seal 2, screen cloth 3) and cylinder 4 by being threaded.
2. the filler stem of handling well is packed into from the other end is disposable.
3. wait filler to be deposited into back (in case of necessity, compacting) in the cylinder fully, with column cap 1 (containing seal 2, screen cloth 3) by being threaded onto the other end of cylinder 4.
4. connect and import and export the associative operation that carries out separation and purification, i.e. chromatography.
5. after chromatography finishes, unload two ends column cap up and down, get filler in the cylinder by impressed pressure.
It more than is typical what is called " dry column-packing " process.In the laboratory, need what is called " wet method dress post " sometimes.At this moment can use chromatographic column assembly 300 according to another technical scheme of the utility model.Referring to Fig. 5, Fig. 6, Fig. 7, Fig. 8.Fig. 5 is the assembled state schematic diagram according to the chromatographic column assembly 300 of another technical scheme of the utility model.Fig. 6 is the decomposing schematic representation of chromatographic column assembly 300.Fig. 7 is the amplification view of element 5 in the chromatographic column assembly 300 shown in Figure 5.Fig. 8 is the amplification plan view of element 6 in the chromatographic column assembly 300 shown in Figure 5.
From Fig. 5,6,7,8 as can be seen, chromatographic column assembly 300 comprises column cap 1, seal 2, screen cloth 3, cylinder 4, connector 5, sealing ring 6 and auxiliary tubing string 7.
Wherein column cap 1, seal 2, and screen cloth 3, cylinder 4 is identical with respective element in the chromatographic column assembly 100, repeats no more.
In order to seal, a sealing ring 6 is arranged usually between cylinder 4 and auxiliary tubing string 7.Sealing ring 6 is annular shims, and its material is identical with seal 2 usually.
In the chromatographic column assembly 300, cylinder 4 is identical with auxiliary tubing string 7 calibers, and external screw thread pitch is also identical, is convenient to processing like this, and makes that column cap 1 can be general.But those skilled in the art understand, the utility model is not only for therewith, for specific purposes, can adopt the auxiliary tubing string 7 with cylinder 4 different tube diameters, this moment, corresponding connector 5 need have the internal diameter of variation so that match with cylinder 4 and auxiliary tubing string 7 respectively.
In addition, when the inventor found that the thread turns of column cap 1, cylinder 4, auxiliary column jecket 7 is 4.5 circles, effect was good especially, can realize the well balanced of ease of processing and sealing.
The chromatography experimentation of chromatographic column assembly 300 is as follows:
With an end of column cap 1 (containing seal 2, screen cloth 3) and cylinder 4 by being threaded.
2. the other end of cylinder 4 connects an end of assisting column jecket 7 by connector 5, will add sealing ring 6 in the middle of noting.
3. pack into from auxiliary column jecket 7 other ends the homogenate filler of handling well is disposable, will fill cylinder 4 fully usually, will account for a part of volume of auxiliary tubing string 7 simultaneously.
4. after waiting filler to be deposited in the cylinder 4 fully, unload auxiliary column jecket 7, connector 5, sealing ring 6.
With column cap 1 (containing seal 2, screen cloth 3) by being threaded onto the other end of cylinder 4.
6. connect and import and export the associative operation that carries out separation and purification, i.e. chromatography.
7. after chromatography finishes, unload two ends column cap up and down, get filler in the cylinder by impressed pressure.
According to the actual demand in the work, can select cylinder, the void column pipe of suitable internal diameter, length, regulate flow velocity, pressure, select different eluting solvents for use.
The utility model chromatographic column modular construction is simple, good airproof performance, can conveniently carry out disposable filler filling, and is for convenience detach.Suitably select the material and the wall thickness of cylinder, can make the withstand voltage 1MPa of reaching of the utility model chromatographic column assembly, can guarantee the flow velocity of chromatography process stabilization thus, reach chromatography effect preferably by the control of pressure; By regulating pressure, adjust the flow velocity of chromatography process, reduce the spent time in the chromatography process.Suitably select the material of column cap, seal and screen cloth, can make the utility model chromatographic column assembly tolerate all organic solvents, the chromatography process can be selected elution requirement widely, make the sample separation better effects if, the scope of application is wider, and especially active ingredient is separated in Chinese herbal medicine, natural products, the zymotic fluid.In addition, the utility model chromatographic column component price is cheap, but repeated multiple times is used the minimizing waste of material.
More than the utility model is described in detail, wherein stated a lot of concrete features, but the utility model is not limited to specific implementations described above in conjunction with specific embodiment.In each specific embodiment, above-mentioned various concrete features also are not limited to described combination, but can make up arbitrarily.Any falling into all should be considered as falling within the protection domain of the present utility model to the substituting of the utility model specific embodiment, distortion and improvement and equivalent thereof in the scope of the present utility model that claim limits.
Claims (10)
1. a chromatographic column assembly is characterized in that, described chromatographic column assembly comprises column cap (1), seal (2), screen cloth (3), cylinder (4), wherein:
Cylinder (4) is a cylindric hollow column jacket, is formed with external screw thread (44) at two end outer wall;
Column cap (1) profile is the cap shape, and its inwall is formed with the internal thread (14) that matches with the external screw thread (44) of cylinder (4), and column cap (1) top is formed with through hole (10);
Seal (2) and screen cloth (3) are shaped as and can place the effect of playing sealing within the column cap (1) and filtering;
And seal (2) is formed with through hole (20) in the corresponding position of through hole (10) with column cap (1).
2. chromatographic column assembly according to claim 1 is characterized in that: described seal (2) is directly placed within the column cap (1) to cooperate with the inwall of column cap (1) to play sealing function; And seal (2) is formed with a cavity, and described screen cloth (3) is placed within the described cavity.
3. medium pressure chromatography column assembly according to claim 1 is characterized in that: described seal (2) and screen cloth (3) are directly placed within the column cap (1) separately.
4. chromatographic column assembly according to claim 1 is characterized in that: described seal (2) and screen cloth (3) are placed in the upper position place at close column cap (1) top within the column cap (1).
5. chromatographic column assembly according to claim 1 is characterized in that: at least two in described column cap (1), seal (2) and the screen cloth (3) are combined into one.
6. according to each described chromatographic column assembly among the claim 1-5, it is characterized in that: the thread turns of described external screw thread (44) and internal thread (14) is 4.5.
7. according to each described chromatographic column assembly among the claim 1-5, it is characterized in that: described chromatographic column assembly also comprises connector (5), sealing ring (6) and auxiliary tubing string (7), wherein:
Auxiliary tubing string (7) is a cylindric hollow column jacket, is formed with external screw thread (74) at its at least one end outer wall;
Connector (5) is a round buss, and its inwall is formed with the internal thread that cooperates respectively with external screw thread (44) and external screw thread (74);
Sealing ring (6) is an annular shim, is placed in when being connected between cylinder (4) and the auxiliary tubing string (7) by connector (5) with auxiliary tubing string (7) at cylinder (4).
8. chromatographic column assembly according to claim 7 is characterized in that: described auxiliary tubing string (7) is identical with cylinder (4) caliber.
9. chromatographic column assembly according to claim 7 is characterized in that: (7) two end outer walls of described auxiliary tubing string all are formed with external screw thread (74), and the thread turns of external screw thread (74) is 4.5.
10. according to each described chromatographic column assembly among the claim 1-5, it is characterized in that: described chromatographic column assembly also comprises the plug that matches with the top through hole (10) of column cap (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920000139U CN201379989Y (en) | 2009-01-05 | 2009-01-05 | Chromatographic column assembly |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920000139U CN201379989Y (en) | 2009-01-05 | 2009-01-05 | Chromatographic column assembly |
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| CN201379989Y true CN201379989Y (en) | 2010-01-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200920000139U Expired - Fee Related CN201379989Y (en) | 2009-01-05 | 2009-01-05 | Chromatographic column assembly |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103691155A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable chromatographic column |
| CN103691151A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN103691150A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable chromatographic column |
| CN103691154A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Chromatographic column for protein purification |
| CN103691156A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Antiskid chromatographic column |
| CN103691157A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Controllable-flow-rate chromatographic column |
| CN103691153A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Chromatographic column for protein purification |
| CN107717250A (en) * | 2017-10-10 | 2018-02-23 | 固安县惠民塑料滤业有限公司 | A kind of connection method for Johnson's pipe being used in backwash filter |
| CN112924604A (en) * | 2019-12-06 | 2021-06-08 | 劢析科学仪器(苏州)有限公司 | Ion pair purifying column |
| CN113082770A (en) * | 2019-12-23 | 2021-07-09 | 江苏汉邦科技有限公司 | Be applied to rotary device of chromatography column |
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2009
- 2009-01-05 CN CN200920000139U patent/CN201379989Y/en not_active Expired - Fee Related
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103691151B (en) * | 2013-12-05 | 2016-04-06 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN103691156A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Antiskid chromatographic column |
| CN103691155A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable chromatographic column |
| CN103691154A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Chromatographic column for protein purification |
| CN103691157B (en) * | 2013-12-05 | 2016-05-11 | 成都雅途生物技术有限公司 | The chromatographic column that flow velocity is controlled |
| CN103691157A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Controllable-flow-rate chromatographic column |
| CN103691153A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Chromatographic column for protein purification |
| CN103691154B (en) * | 2013-12-05 | 2016-05-11 | 成都雅途生物技术有限公司 | A kind of chromatographic column for protein purification |
| CN103691150A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable chromatographic column |
| CN103691151A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN103691150B (en) * | 2013-12-05 | 2016-04-06 | 成都雅途生物技术有限公司 | A kind of detachable chromatographic column |
| CN103691153B (en) * | 2013-12-05 | 2016-05-11 | 成都雅途生物技术有限公司 | For the chromatographic column of protein purification |
| CN103691156B (en) * | 2013-12-05 | 2016-08-31 | 成都雅途生物技术有限公司 | Antiskid chromatographic column |
| CN107717250A (en) * | 2017-10-10 | 2018-02-23 | 固安县惠民塑料滤业有限公司 | A kind of connection method for Johnson's pipe being used in backwash filter |
| CN112924604A (en) * | 2019-12-06 | 2021-06-08 | 劢析科学仪器(苏州)有限公司 | Ion pair purifying column |
| CN112924604B (en) * | 2019-12-06 | 2023-12-26 | 劢析科学仪器(苏州)有限公司 | Ion pair purifying column |
| CN113082770A (en) * | 2019-12-23 | 2021-07-09 | 江苏汉邦科技有限公司 | Be applied to rotary device of chromatography column |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| DD01 | Delivery of document by public notice |
Addressee: Li Yuntian Document name: Notification to Pay the Fees |
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| DD01 | Delivery of document by public notice |
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| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100113 Termination date: 20110105 |