CN201025480Y - An immune hierarchical analysis multiple detection testing paper tray - Google Patents

An immune hierarchical analysis multiple detection testing paper tray Download PDF

Info

Publication number
CN201025480Y
CN201025480Y CNU2007201037780U CN200720103778U CN201025480Y CN 201025480 Y CN201025480 Y CN 201025480Y CN U2007201037780 U CNU2007201037780 U CN U2007201037780U CN 200720103778 U CN200720103778 U CN 200720103778U CN 201025480 Y CN201025480 Y CN 201025480Y
Authority
CN
China
Prior art keywords
test paper
paper disk
drainage
drain pan
loam cake
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNU2007201037780U
Other languages
Chinese (zh)
Inventor
周蕾
杜宗敏
杨瑞馥
黄惠杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Microbiology and Epidemiology of AMMS
Original Assignee
Institute of Microbiology and Epidemiology of AMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Microbiology and Epidemiology of AMMS filed Critical Institute of Microbiology and Epidemiology of AMMS
Priority to CNU2007201037780U priority Critical patent/CN201025480Y/en
Application granted granted Critical
Publication of CN201025480Y publication Critical patent/CN201025480Y/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Landscapes

  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The utility model provides an immunity chromatography multi-detection test paper disk, which includes a bottom shell of test paper disk, an upper cover of the test paper disk which can cover on bottom shell of the test paper disk, and a drainage tablet positioned between the test paper strip of the bottom shell of test paper disk and the upper cover of the test paper disk. A sample feeding hole right opposite to the drainage tablet is arranged on the upper cover of the test paper disk. The sample feeding hole is communicated to a drainage groove positioned in the inner side of the upper cover and composed by plurality of drainage channels. The test paper strip carrying platform, the positions and number of which match with the drainage channels of the upper cover, are disposed on the bottom shell referred. The edge of the drainage tablet referred is lapped on the sample pad which locates on the end of the test paper strip carried by the test paper strip carrying platform near to the sample feeding hole. The utility model solves problems of uneven distribution of liquid sample, uneven chromatography reaction, and the loss generated by liquid sample overflow in the combined detection model of the prior art by special arrangement style of the test paper strips, the utilization of the drainage tablet, and the design of the drainage groove on the outer shell of the test paper disk, thus the even rapid simultaneous detection can be carried smoothly.

Description

A kind of immunochromatography multiple detection test paper disk
Technical field:
The utility model belongs to the immune diagnostic technique field, is specifically related to the immunity-chromatography test paper disc in the multiple detection technique of a kind of immunochromatography, makes that a duplicate samples is carried out single job can obtain the testing result whether the plurality of target checking matter exists.
Background technology:
Immunochromatography technique is a kind of comparatively ripe field quick detection technology.Traditional immune chromatography test paper is referring to shown in Figure 1, mainly consist of the following components: analyzing film (main material is a nitrocellulose filter) 101, pad (main material is a glass fibre) 102, sample pad (main material is glass fibre or thieving paper) 103, adsorptive pads (main material is a thieving paper) 104, various piece is pasted according to certain overlapping relation and is fixed on the viscosity end liner 105.Overlapped between the each part mentioned above guaranteed the continuity that liquid flows on test strips.When detecting, sample drop is added on the sample pad 103, sample enters pad 102 by infiltration and syphonic effect, make label-bioactive molecule bond wherein dissolve free again, and under the syphonic effect of adsorptive pads 104, leave pad 102 and enter film, portion flows to the direction of adsorptive pads 104 within it.Bond in this process, target checking matter, detect with 106, certain immune response will take place specifically between the quality control band 107, and produce and have tell-tale signal.The label that produces indicative signal commonly used is collaurum, fluorescein, dyestuff etc.Yet, no matter be which kind of immune chromatography test paper, its detecting pattern of taking is: a duplicate samples is carried out experimental implementation one time, obtain the testing result whether a kind of target checking matter exists, be i.e. " one to one " detecting pattern.This pattern when suspicious specimen is carried out the examination of plurality of target checking matter, complex operation, and last longer.
The utility model content:
The purpose of this utility model is to overcome that technology " one to one " detecting pattern formerly caused is loaded down with trivial details, last shortcomings such as long, a kind of immunochromatography multiple detection test paper disk is provided, can realize a duplicate samples is carried out an experimental implementation and detected when finishing the plurality of target checking matter, i.e. " one-to-many " detecting pattern.
Technical solution of the present utility model is as follows:
A kind of immunochromatography multiple detection test paper disk, comprise a test paper disk drain pan, the one test paper disk loam cake that can cover with the test paper disk drain pan, and one place test strips on the test paper disk drain pan and the drainage sheet between the test paper disk loam cake, described test paper disk loam cake is established well, and well is over against the drainage sheet, described well is communicated with one and is located at the drainage trough that the loam cake inner face is made up of a plurality of drainage channels, described drain pan is established a plurality of drainage channels position and the corresponding test strips plummer of quantity with loam cake, and described drainage sheet overlapping edges is on the close sample pad of well one end of the test strips of being carried on the described test strips plummer.
In the above-mentioned immunochromatography multiple detection test paper disk, described test paper disk is circular, square, rectangle, rhombus, the arbitrary geometric configuration of regular polygon, described well is located at the geometric center position of geometric configuration, and many test strips plummers of described test paper disk drain pan are arranged with center symmetric form or axial symmery shape.
In the above-mentioned immunochromatography multiple detection test paper disk, each plummer edge is distributed with fixedly washer of many groups, establishes the value number district at each plummer near test paper disk drain pan edge direction.
In the above-mentioned immunochromatography multiple detection test paper disk, described test strips plummer is made up of three roads projectioies, and close symcenter or axis of symmetry one end are by sealing with high washer.
In the above-mentioned immunochromatography multiple detection test paper disk, described test paper disk loam cake inner face is provided with many group compressing tablets at the passage of the described drainage trough location interval that stretches out, and also order is interrupted and is provided with view window, terminal point indicating window and the nail that falls as a result.
In the above-mentioned immunochromatography multiple detection test paper disk, be distributed with the recessed rivet of many rows on the test paper disk drain pan, correspondence is established protruding rivet at the loam cake inner face.
In the above-mentioned immunochromatography multiple detection test paper disk, described drainage channel is made up of two flash and a low limit, and all drainage channels are linked in sequence successively; The extension of described flash inner face and described plummer sting and and direct reach the bottom surface of test paper disk drain pan; The relation of the high h2 on described low limit and the high h1 of flash is:
H2=h1-(plummer height+test strips viscosity end liner thickness+test strips sample pad thickness).
Concrete, the test paper disk of described immunochromatography multiple detection test paper disk is circle, rhombus or regular polygon, and described well is located at the geometric center position, and many test strips plummers of described test paper disk drain pan are arranged with the center symmetric form.
Perhaps, described test paper disk is square or rectangle, and described well is located on the axis of symmetry, and many test strips plummers of described test paper disk drain pan are arranged in the axis of symmetry symmetria bilateralis.
Above-mentioned immunochromatography multiple detection test paper disk, corresponding test paper disk drain pan value number is established same value number in the loam cake outside, and other establishes the ID window in order to the detection sequence number of mark sample, and the user holds indication, and the direction of insertion indication.
The utility model is set up the multiple detecting pattern of a kind of immunochromatography by designing a kind of special immunity-chromatography test paper disc, makes the panimmunity chromatographic test paper that immunochromatography reaction pair one duplicate samples can take place synchronously uniformly and detects.
Adopt design of the present utility model, the design of drainage trough on use by the special arrangement mode of test strips, drainage sheet and the test paper disk shell, overcome problems such as the fluid sample maldistribution that exists in the joint-detection detecting pattern in the technology formerly, chromatography reaction heterogeneity, fluid sample spill losses, made that synchronous detection is smooth evenly and rapidly in the multiple detecting pattern.
Description of drawings:
Fig. 1: test strips structural drawing
Fig. 2: test paper disk drain pan
Fig. 3 A: test paper disk loam cake inner face
Fig. 3 B: drainage channel structural drawing in the test paper disk loam cake inner face
Fig. 4: test paper disk loam cake outside
Fig. 5: test paper disk assembly drawing
Fig. 6: ten joint inspection test paper disk drain pans of center symmetry
Fig. 7 A: ten joint inspection test paper disk inner faces of center symmetry
Fig. 7 B: drainage channel structural drawing in ten joint inspection test paper disk inner faces of center symmetry
Fig. 8: ten joint inspection test paper disk outsides of center symmetry
Fig. 9: ten joint inspection test paper disk assembly drawings of center symmetry
Figure 10: ten joint inspection test paper disks of rotational symmetry drain pan
Figure 11 A: ten joint inspection test paper disks of rotational symmetry loam cake inner face
Figure 11 B: drainage channel structural drawing in ten joint inspection test paper disks of rotational symmetry loam cake inner face
Figure 12: ten joint inspection test paper disks of rotational symmetry loam cake outside
Figure 13: ten joint inspection test paper disks of rotational symmetry assembly drawing
Embodiment:
The test paper disk of the utility model design comprises four parts: test paper disk drain pan 1 (referring to Fig. 2, Fig. 6, Figure 10), test paper disk loam cake 2 (referring to Fig. 3 A/3B and Fig. 4, Fig. 7 A/7B and Fig. 8, Figure 11 A/11B and Figure 12), drainage sheet 3 (referring to Fig. 5, Fig. 9, Figure 13) and test strips 4 (referring to Fig. 1), described test paper disk drain pan 1 is used after covering with described test paper disk loam cake 2, and described drainage sheet 3 places between the test strips and test paper disk loam cake 2 of being carried on the paper disc drain pan 1.
Test paper disk drain pan 1 includes many test strips plummers 11, and many test strips plummers 11 are arranged with center symmetric form (referring to Fig. 2, Fig. 6) or axial symmery shape form (referring to Figure 10); Each plummer 11 edge be distributed with many groups fixedly washer 12 with high washer 13, establish value number district A1 at each plummer 11 near test paper disk drain pan 1 edge directions, also be distributed with the recessed rivets 14 of arranging on the test paper disk drain pan more;
Continuation is referring to shown in Figure 2, and wherein, said test strips plummer 11 is made up of three roads projection, and near symcenter or axis of symmetry one end by sealing with high washer 13, thereby the spill losses of prevention fluid sample; Said fixedly washer 12, be positioned at around the test strips plummer 11, said test strips plummer 11 and fixedly washer 12 combinations, be used to carry immune chromatography test paper and immune chromatography test paper is fixed, thereby make immune chromatography test paper keep center symmetric form or the axial symmery shape consistent with plummer 11, test strips print pad is gathered in symcenter or axis of symmetry; Said value number district A1 is located at each test strips plummer 11 avris, is used to indicate the variety classes test strips that is carried on the test strips plummer 11; The recessed rivet 14 of said many rows is used for being fastened with test paper disk loam cake 2, and wherein, its interior one group of recessed rivet 14 near symcenter or axis of symmetry can be used for fixing the position of drainage sheet 3 simultaneously as locating pin 15.
Referring to Fig. 3 and shown in Figure 4, test paper disk loam cake 2 comprises test paper disk loam cake inner face and test paper disk loam cake outside, by drainage trough 21, organize compressing tablet 22,23,24 more, follow closely 25, arrange protruding rivet 26 more, well 27, as a result view window 28, terminal point indicating window 29 and value number district B1, ID window B2, hold indication B3 and direction of insertion indication B4 forms; Drainage trough 21, compressing tablet 22,23,24, follow closely 25, protruding rivet 26 is distributed in test paper disk loam cake inner face, well 26, view window 27, terminal point indicating window 28 penetrate test paper disk loam cake 2 inner faces and outside as a result, value number B1, ID window B2, hold indication B3 and direction of insertion indication B4 only is distributed in test strips loam cake outside;
Wherein, said drainage trough 21 is by the drainage channel corresponding with each test strips 20 combined integrated forming; Said drainage channel 20 shown in Fig. 3 B, comprises two flash 201 and a low limit 202; Said flash 201, the extension of its inner face and plummer 11 sting and and direct reach the bottom surface of test paper disk drain pan 1; Said low limit 202, the relation of its high h2 and flash 201 high h1 is: the low high h2=h1-in limit (plummer height+test strips viscosity end liner thickness+test strips sample pad thickness), and be stuck on the print pad 103 and combine closely; Said flash 201 and low limit 202, it is with plummer 11, together constitute the sample cell of sealing and the drainage channel corresponding with each test strips with high washer 13, test strips 4, drainage sheet 3, test paper disk drain pan 1 bottom surface, test paper disk loam cake 2 inner faces;
Said three compressing tablets 22,23,24, successively corresponding to adsorptive pads 104 and analyzing film 101 overlay regions, pad 102 and analyzing film 101 overlay regions, sample pad 103 and pad 102 overlay regions (referring to Fig. 1), thereby guarantee the continuity of liquid flow in the whole test strips; Saidly follow closely 25, can penetrate in the adsorptive pads 104 of test strips, further stablize test strips in case move; Said protruding rivet 26, can with the recessed rivet 14 pairing interlocks on the test paper disk drain pan 1, and then test paper disk loam cake 2 and test paper disk drain pan 1 be fastened; Said well 27 is located at the center of test paper disk loam cake 2, and is corresponding with drainage sheet 3 after test paper disk fastens, and by well 27 fluid sample is added on the drainage sheet 3 during detection; Said view window as a result 28 and terminal point indicating window 29 linearly the property arrangement and with the plummer 11 corresponding settings of drain pan 1, wherein view window 28 is located at the straight line middle section position as a result, it is corresponding with the analyzing film 101 of test strips after test paper disk fastens, interpretation can be carried out to the result on the analyzing film 101 by view window 28 as a result in the detection back that finishes, and terminal point indicating window 29 is located at straight line near test paper disk loam cake 2 edge directions, corresponding with the adsorptive pads 104 of test strips after test paper disk fastens, can monitor the chromatography process by the terminal point indicating window in the testing process;
Said value number B1 is used to indicate the variety classes test strips, and is corresponding one by one with value number A1 on the test paper disk drain pan 1; Said ID window B2 is used to mark the detection sequence number of sample; Said user holds indication B3 and direction of insertion indication B4, is used to point out test paper disk to insert the direction of detector in detection by quantitative;
Referring to shown in Figure 5, drainage sheet 3 can be materials such as glass fibre, filter paper, nonwoven fabrics for having bigger bed volume and the uniform film class of microcosmic result material; Drainage sheet 3 places the position with drainage trough 21 correspondences when assembling, make it to contact with the sample pad 103 of each test strips, and overlap with sample pad 103.
Above component-assembled and form the utility model test paper disk.Assembling process is referring to Fig. 5, comprise and placing test strips, placement drainage sheet, installation three steps of loam cake: at first, according to the value number A1 on the test paper disk drain pan specific test strips is placed on the specific plummer 11, the arrangement mode of plummer 11 and fixedly the positioning action of washer 12 make test strips be center symmetric form or the axial symmery shape that sample pad gathers to arrange; Then, utilize the recessed rivet 14 of innermost layer on the test paper disk drain pan 1 to place drainage sheet 3 as locating pin 15, drainage sheet 3 is overlapped with the sample pad of interior all test strips of test paper disk, drainage sheet 3 bigger bed volumes can prevent that the sample overflow from causing damage, and meanwhile the inner structure of its homogeneous has guaranteed the homogeneity that sample distributes; At last, utilize recessed rivet 14 on the test paper disk drain pan 1 sting with protruding rivet 26 pairings on the test paper disk loam cake 2 and, test paper disk is integrated.Test paper disk after the assembling, the well 27 of loam cake, as a result view window 28, terminal point indicating window 29 respectively be fixed in drain pan 1 on the analyzing film 101 and the adsorptive pads 104 of drainage sheet 3, each test strips corresponding, three compressing tablets 22,23,24 then respectively with each test strips on adsorptive pads 104 and analyzing film 101 overlay regions, pad 102 corresponding with analyzing film 101 overlay regions and print pad 103 with pad 102 overlay regions, thereby guarantee the continuity of each chromatography path.In order better to prevent the sample spill losses and to guarantee the homogeneity that each test paper chromatography reacts, test strips loam cake 2 inner faces have designed unique drainage trough 21, comprise the drainage channel corresponding 20 with each test strips, the inner face of these drainage channel 20 both sides flash 201 and the extension of plummer 11 sting and and direct reach the bottom surface of test paper disk drain pan 1, middle low limit 202 is stuck on the print pad combines closely.Plummer 11 center of area ends are by sealing with high washer 13 in addition, thus after test strips drain pan and loam cake button and sealing, plummer 11, the sample cell of sealing and the drainage channel corresponding have together been constituted with each test strips with high washer 13, test strips 4, drainage sheet 3, drainage trough 21 and drain pan 1 bottom surface and loam cake 2 inner faces, thereby when preventing sample loss, guarantee that each test strips absorbs the synchronism and the homogeneity of sample.
In sum, the utility model test paper disk mainly comprises following three technical essentials:
1. the test strips arrangement mode of center symmetric form or axial symmery shape guarantees each test strips absorption uniformity of sample;
2. with the partly overlapping drainage sheet of each test strips sample pad, have the spill losses that bigger bed volume can prevent fluid sample, have the homogeneity that uniform micromechanism can guarantee that sample distributes simultaneously;
3. the drainage trough of test paper disk loam cake inner face can constitute the reaction and the drainage space of sealing with the test paper disk drain pan, when preventing the sample spill losses, guarantees the homogeneity of each test strips reaction;
More than said test paper disk, from can be arbitrary geometric configuratioies such as circle, square, rhombus, regular polygon in shape; And said test paper disk can carry N test strips, and N is a natural number.Therefore, the utility model test paper disk can have the variation of various ways, below with specific embodiment it is described, but is not limited to following described embodiment.
Embodiment 1: six joint inspection test paper disks of center symmetry
The structure that Fig. 2 to Fig. 5 has described six joint inspection test paper disks of center symmetry constitutes and assembling process, this embodiment test paper disk is regular hexagon in shape, is symcenter with the hexagon geometric center, and being designed to carry six test strips, the sample pad 103 of test strips is all pointed to symcenter; Particular content is described in detail in the above in conjunction with the accompanying drawings, repeats no more.
Embodiment 2: ten joint inspection test paper disks of center symmetry
On the basis of foregoing description, extremely shown in Figure 9 referring to Fig. 6.Symmetry ten joint inspection test paper disks in present embodiment center specifically are made of test paper disk drain pan 1 (Fig. 6), test paper disk loam cake 2 (Fig. 7 and Fig. 8), drainage sheet 3 and test strips 4 (Fig. 9).Test paper disk drain pan 1 comprises: fixedly washer 12, ten are with the recessed rivet of high washer 13, ten rows 14, ten value number A1 for ten plummers 11, ten groups, and test paper disk loam cake 2 comprises: 22,23,24, ten groups of the drainage troughs formed by ten passages 20 21, ten groups of compressing tablets follow closely the protruding rivet 26 of 25, ten rows, well 27, ten as a result view window 28, ten terminal point indicating windows 29, ten value number B1, ID window B2, hold indication B3, direction of insertion is indicated B4.
Its assembling process (Fig. 9) comprising: place test strips 4, place drainage sheet 3, loam cake 2 is installed, the test paper disk that assembling is finished can make ten kinds of immune chromatography test papers realize the chromatography reaction of homogeneous by various particular design.Plummer 11 is arranged with the center symmetric form, it 25 cooperates and ten kinds of test strips are arranged with the center symmetric form and keep sample pad 103 to gather to the center with following closely of fixedly washer 12 and loam cake, thereby guarantees that from space structure various test strips 4 can carry out the chromatography reaction of homogeneous; The recessed rivet 14 of innermost layer is when the protruding rivet 26 pairing effects with loam cake fasten test paper disk on the drain pan 1, it is fixing and the sample pad 103 of itself and each test strips 4 is overlapped with drainage sheet 3 also to can be used as locating pin 15, thereby utilize bigger bed volume of drainage sheet 3 and inner structure uniformly, but make fluid sample be difficult for spill losses and uniform distribution, further guarantee the homogeneity of various test strips reactions; The drain pan 1 of test paper disk fastens to one makes the compressing tablet 22,23,24 of loam cake 2 inner faces can be pressed on the adsorptive pads 104 and analyzing film 101 overlay regions, pad 102 and analyzing film 101 overlay regions, sample pad 103 and pad 102 overlay regions of test strips respectively with loam cake 2, thereby guarantees the continuity of the inner chromatography reaction of test strips; The drainage trough 21 of test paper disk loam cake 2 inner faces is made of ten combined integrated drainage channels 20 corresponding with each test strips 4, each drainage channel 20 comprises two flash 201 and a low limit 201, two flash, 201 inner faces can and direct reach drain pan 1 bottom surface with plummer 11 extension interlocks, and high h1 of flash and the high h2 in low limit have following relation:
The low high h2=h1-in limit (plummer height+test strips viscosity end liner thickness+test strips sample pad thickness)
This height relationships can be stuck on the print pad 103 low limit 202 and combines closely guaranteeing that flash 201 stings with plummer 11 and block in drain pan 1 bottom surface.Plummer 11 center of area ends are by sealing with high washer 13 in addition, fasten back plummer 11, can constitute the sample cell and the immunochromatography path of complete closure at test paper disk thus, thereby when preventing the sample spill losses, guarantee each test strips absorption uniformity of sample with high washer 13, test strips 4, drainage sheet 3, drainage trough 21, drain pan 1 bottom surface, loam cake 2 inner faces.Complete test paper disk can be added on fluid sample on the drainage sheet 3 by well 27 in the process of actual detected, thereby opens beginning immune detection reaction; But, and can carry out interpretation to net result by the view window as a result 28 corresponding with analyzing film by the process of the terminal point indicating window 29 auxiliary judgment immunochromatographies reaction corresponding with adsorptive pads 104; For using instrument to carry out the test strips of detection by quantitative, hold indication B3 and direction of insertion indication B4 on the test paper disk and can point out test paper disk to insert the direction of detector.
Finally, utilize ten joint inspection test paper disks of center symmetry make ten kinds of different immune chromatography test papers synchronously the chromatography that carries out of homogeneous react, and can carry out interpretation intuitively to net result.
Embodiment 3: ten joint inspection test paper disks of rotational symmetry
On the basis of foregoing description, extremely shown in Figure 13 referring to Figure 10.Ten joint inspection test paper disks of present embodiment rotational symmetry are rectangle in shape, and the axis of symmetry both sides are arranged 5 test strips respectively and made the sample pad 103 close axis of symmetry of test strips; Concrete, ten joint inspection test paper disks of rotational symmetry are made of test paper disk drain pan 1 (Figure 10), test paper disk loam cake 2 (Figure 11 and 12), drainage sheet 3 and test strips 4 (Figure 13).Test paper disk drain pan 1 comprises: plummer 31, fixedly washer 32, with high washer 33, recessed rivet 34, projection nail 35, value number C1, test paper disk loam cake 2 comprises: drainage trough 41, compressing tablet 42,43,44, follow closely 45, protruding rivet 46, well 47, as a result view window 48, terminal point indicating window 49, value number D1, ID window D2, hold indication D3, direction of insertion indication D4.
Its assembling process (Figure 13) comprising: place test strips 4, place drainage sheet 3, loam cake 2 is installed, the test paper disk that assembling is finished can make ten kinds of immune chromatography test papers realize the chromatography reaction of homogeneous by various particular design.Plummer 31 is arranged with axial symmery shape, it 45 cooperates and ten kinds of test strips are arranged with axial symmery shape and keep sample pad to gather to axis of symmetry with following closely of fixedly washer 32 and loam cake, thereby guarantees that from space structure various test strips can carry out the chromatography reaction of homogeneous; Recessed rivet 34 on the drain pan is when the protruding rivet 46 pairing effects with loam cake fasten test paper disk, two recessed rivets 34 that are positioned on the drain pan on the axis of symmetry can be used as locating pin 36 with other 4 projection nails 35, drainage sheet 3 is fixing and the sample pad 103 of itself and each test strips is overlapped, thereby utilize bigger bed volume of drainage sheet and uniform inner structure, but make fluid sample be difficult for spill losses and uniform distribution, further guarantee the homogeneity of various test strips reactions; The drain pan 1 of test paper disk fastens to one makes the compressing tablet 42,43,44 of loam cake inner face can be pressed on the adsorptive pads 104 and analyzing film 101 overlay regions, pad 102 and analyzing film 101 overlay regions, sample pad 103 and pad 102 overlay regions of test strips respectively with loam cake 2, thereby guarantees the continuity of the inner chromatography reaction of test strips; The drainage trough 41 of test paper disk loam cake inner face is made of ten combined integrated drainage channels 40 corresponding with each test strips, each drainage channel 40 comprises two flash 401 and a low limit 402, link to each other with web joint 403 between the drainage channel in twos 40 of axis of symmetry one side, link to each other with web joint 404 between the drainage channel in twos 40 of axis of symmetry both sides, two flash inner faces can and direct reach the drain pan bottom surface with plummer 31 extension interlocks, and high h1 of flash and the high h2 in low limit have following relation:
The low high h2=h1-in limit (plummer height+test strips viscosity end liner thickness+test strips sample pad thickness)
This height relationships can be stuck on the print pad 103 low limit 402 and combines closely guaranteeing that flash 401 stings with plummer 31 and block in drain pan 1 bottom surface.Plummer 31 over glaze ends are by sealing with high washer 33 in addition, fasten back plummer 31, can constitute the sample cell and the immunochromatography path of complete closure at test paper disk thus, thereby when preventing the sample spill losses, guarantee each test strips absorption uniformity of sample with high washer 33, test strips 4, drainage sheet 3, drainage trough 41, drain pan 1 bottom surface, loam cake 2 inner faces.Complete test paper disk can be added on fluid sample on the drainage sheet 3 by well 47 in the process of actual detected, thereby opens beginning immune detection reaction; But, and can carry out interpretation to net result by the view window as a result 48 corresponding with analyzing film 101 by the process of the terminal point indicating window 49 auxiliary judgment immunochromatographies reaction corresponding with print pad 103; For using instrument to carry out the test strips of detection by quantitative, hold indication D3 and direction of insertion indication D4 on the test paper disk and can point out test paper disk to insert the direction of detector.
Finally, utilize ten joint inspection test paper disks of rotational symmetry make ten kinds of different immune chromatography test papers synchronously homogeneous carry out chromatography reaction, and can carry out interpretation intuitively to net result.

Claims (10)

1. immunochromatography multiple detection test paper disk, it is characterized in that, comprise a test paper disk drain pan, the one test paper disk loam cake that can cover with the test paper disk drain pan, and one place test strips on the test paper disk drain pan and the drainage sheet between the test paper disk loam cake, described test paper disk loam cake is established well, and well is over against the drainage sheet, described well is communicated with one and is located at the drainage trough that the loam cake inner face is made up of a plurality of drainage channels, described drain pan is established a plurality of drainage channels position and the corresponding test strips plummer of quantity with loam cake, and described drainage sheet overlapping edges is on the close sample pad of well one end of the test strips of being carried on the described test strips plummer.
2. according to the described immunochromatography multiple detection test paper disk of claim 1, it is characterized in that, described test paper disk is circular, square, rectangle, rhombus, the arbitrary geometric configuration of regular polygon, described well is located at the geometric center position of geometric configuration, and many test strips plummers of described test paper disk drain pan are arranged with center symmetric form or axial symmery shape.
3. according to the described immunochromatography multiple detection test paper disk of claim 2, it is characterized in that each plummer edge is distributed with fixedly washer of many groups, establishes the value number district at each plummer near test paper disk drain pan edge direction.
4. according to the described immunochromatography multiple detection test paper disk of claim 3, it is characterized in that described test strips plummer is made up of three roads projectioies, and close symcenter or axis of symmetry one end are by sealing with high washer.
5. according to the described immunochromatography multiple detection test paper disk of claim 3, it is characterized in that, described test paper disk loam cake inner face is provided with many group compressing tablets at the passage of the described drainage trough location interval that stretches out, and also order is interrupted and is provided with view window, terminal point indicating window and the nail that falls as a result.
6. according to the described immunochromatography multiple detection test paper disk of claim 5, it is characterized in that be distributed with the recessed rivet of many rows on the test paper disk drain pan, correspondence is established protruding rivet at the loam cake inner face.
7. according to the arbitrary described immunochromatography multiple detection test paper disk of claim 1 to 6, it is characterized in that described drainage channel is made up of two flash and a low limit, and all drainage channels are linked in sequence successively; The extension of described flash inner face and described plummer sting and and direct reach the bottom surface of test paper disk drain pan; The relation of the high h2 on described low limit and the high h1 of flash is:
H2=h1-(plummer height+test strips viscosity end liner thickness+test strips sample pad thickness).
8. according to the described immunochromatography multiple detection test paper disk of claim 7, it is characterized in that, described test paper disk is circle, rhombus or regular polygon, and described well is located at the geometric center position, and many test strips plummers of described test paper disk drain pan are arranged with the center symmetric form.
9. according to the described immunochromatography multiple detection test paper disk of claim 7, it is characterized in that described test paper disk is square or rectangle, described well is located on the axis of symmetry, and many test strips plummers of described test paper disk drain pan are arranged in the axis of symmetry symmetria bilateralis.
10. according to Claim 8 or 9 described immunochromatography multiple detection test paper disks, it is characterized in that corresponding test paper disk drain pan value number is established same value number in the loam cake outside, other establishes the ID window in order to the detection sequence number of mark sample, the user holds indication, and the direction of insertion indication.
CNU2007201037780U 2007-03-09 2007-03-09 An immune hierarchical analysis multiple detection testing paper tray Expired - Lifetime CN201025480Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNU2007201037780U CN201025480Y (en) 2007-03-09 2007-03-09 An immune hierarchical analysis multiple detection testing paper tray

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNU2007201037780U CN201025480Y (en) 2007-03-09 2007-03-09 An immune hierarchical analysis multiple detection testing paper tray

Publications (1)

Publication Number Publication Date
CN201025480Y true CN201025480Y (en) 2008-02-20

Family

ID=39099339

Family Applications (1)

Application Number Title Priority Date Filing Date
CNU2007201037780U Expired - Lifetime CN201025480Y (en) 2007-03-09 2007-03-09 An immune hierarchical analysis multiple detection testing paper tray

Country Status (1)

Country Link
CN (1) CN201025480Y (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103149353A (en) * 2013-02-05 2013-06-12 中国科学院上海光学精密机械研究所 Quantitative detection system and detection method for multi-channel test paper disc
CN103954752A (en) * 2014-05-06 2014-07-30 太仓浩湖五金制品有限公司 Test table for immune colloidal gold test paper
CN106222081A (en) * 2016-08-31 2016-12-14 北京中科圆融生物科技发展有限公司 Single centre multi-channel assembled detection device
WO2020143219A1 (en) * 2019-01-11 2020-07-16 广州万孚生物技术股份有限公司 Sample loading bottom plate and immunochromatography detection apparatus containing sample loading bottom plate
CN112881372A (en) * 2021-01-11 2021-06-01 丰能医药科技(上海)有限责任公司 Convenient physiological health index detection technology

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103149353A (en) * 2013-02-05 2013-06-12 中国科学院上海光学精密机械研究所 Quantitative detection system and detection method for multi-channel test paper disc
CN103149353B (en) * 2013-02-05 2015-05-13 中国科学院上海光学精密机械研究所 Quantitative detection system and detection method for multi-channel test paper disc
CN103954752A (en) * 2014-05-06 2014-07-30 太仓浩湖五金制品有限公司 Test table for immune colloidal gold test paper
CN103954752B (en) * 2014-05-06 2016-03-16 太仓市高泰机械有限公司 A kind of test board of immune colloidal gold test paper
CN106222081A (en) * 2016-08-31 2016-12-14 北京中科圆融生物科技发展有限公司 Single centre multi-channel assembled detection device
CN106222081B (en) * 2016-08-31 2019-01-15 北京中科圆融生物科技发展有限公司 The multi-channel assembled detection device of single centre
WO2020143219A1 (en) * 2019-01-11 2020-07-16 广州万孚生物技术股份有限公司 Sample loading bottom plate and immunochromatography detection apparatus containing sample loading bottom plate
CN112881372A (en) * 2021-01-11 2021-06-01 丰能医药科技(上海)有限责任公司 Convenient physiological health index detection technology

Similar Documents

Publication Publication Date Title
CN101261270B (en) Immunity-chromatography multiple detection test paper disk and immunity-chromatography multiple detection method
CN201025480Y (en) An immune hierarchical analysis multiple detection testing paper tray
US5798272A (en) Method for plasma separation and measurement
JP2010520991A5 (en)
US5082626A (en) Wedge shaped test strip system useful in analyzing test samples, such as whole blood
US8202487B2 (en) Multiple analyte assay devices
CN206038690U (en) Multiple pick -up plate of single -site multichannel immunity chromatography
CN1318142C (en) Diagnostic devices
US8158080B2 (en) Biosensor
CN201156047Y (en) Cup cover for sample detection
CN106198950A (en) For depositing paper box and the sample testing apparatus of Test paper
CN208270584U (en) Multichannel immunochromatography label pad and detection reagent card
CN207913802U (en) A kind of micro-fluidic chip and its detection device of whole blood test
CN202453356U (en) Detecting device for achieving accurate testing by controlling flowing speed of sample
KR20220025857A (en) Blood group antigen detection component
CN207571147U (en) For the test strips of fluorescence immune chromatography method detection
CN212111434U (en) Detection card shell
CN218350304U (en) Thyroid stimulating hormone immunochromatography detection kit
CN105891519B (en) A kind of kit and assay method for being used to determine glycosylated hemoglobin ratio
CN111474342A (en) Colloidal gold detection card for four-item joint detection of drugs and method for detecting drugs
CN215339892U (en) Immunochromatography multi-connection reagent card
CN209656714U (en) A kind of push type multichannel chromatographic apparatus
CN202093024U (en) Myocardial infarction three-in-one gold-labeled rapid cassette test
CN220207623U (en) Multifunctional bidirectional chromatography detection test strip
CN212228965U (en) Blood type detection reagent plate simply and conveniently dripped

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20080220

Effective date of abandoning: 20070309

AV01 Patent right actively abandoned

Granted publication date: 20080220

Effective date of abandoning: 20070309

RGAV Abandon patent right to avoid regrant