CN1994374A - Preparation method of papermulberry extract and use thereof - Google Patents
Preparation method of papermulberry extract and use thereof Download PDFInfo
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- CN1994374A CN1994374A CNA200610124141XA CN200610124141A CN1994374A CN 1994374 A CN1994374 A CN 1994374A CN A200610124141X A CNA200610124141X A CN A200610124141XA CN 200610124141 A CN200610124141 A CN 200610124141A CN 1994374 A CN1994374 A CN 1994374A
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- papermulberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a method for preparing the papermulberry extractive, wherein it comprises that: collecting stem, leaf or skin of papermulberry; breaking, adding water or wine to immerge it for 12-24h; filtering out foreign materials, to obtain water extractive or wine extractive or water-wine extractive; naturally depositing, taking clear liquid; using vacuum drying method to concentrate it to obtain papermulberry extractive or using freezing drying method to obtain powder or using atomizing drying method to obtain powder or extractive. The inventive extractive can be used directly or as material to prepare agent.
Description
[technical field]
The present invention relates to a kind of preparation method and its usage that disease derives from plant extract that is used for the treatment of, particularly relate to the preparation method and its usage that derives from papermulberry extract.
[background technology]
Tinea is the pain in the necks of people, particularly lives in the humid region, and people are easy to suffer from tinea, very itch unbearably after suffering from tinea, emotion degenerates, and it is all incurring dislike what is seen, what thing is not wanted is done, and does not find out door, is afraid of that others dislikes and avoids, though the medicine of a lot of treatment tineas is arranged on the market, all be that medication a period of time is all right basically, the drug withdrawal tinea can be suffered from again, again and again, tinea thorough cancellation is not controlled table and is not effected a permanent cure, spent many money, tinea is not still cured.
[summary of the invention]
The present invention is directed to the above-mentioned defective of prior art, the preparation method and its usage of papermulberry extract that provides a kind of, it can thoroughly treat tinea, has short treating period, rapid-action, advantage such as method is simple, can also be to the cancer patient with better curative effect is arranged.
In order to solve the problems of the technologies described above, the preparation method of papermulberry extract of the present invention may further comprise the steps:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) again with the aqueous extract natural sedimentation of this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
The preparation method of above-mentioned papermulberry extract can also may further comprise the steps in order to the preparation of below method:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, with content is that the ethanol of 50%-70% adds in this container A, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, ethanol in this container A is filtered, and the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container B;
(2) again with the alcoholic extract natural sedimentation in this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
The preparation method of above-mentioned papermulberry extract can also may further comprise the steps in order to the preparation of below method:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) be that the ethanol of 50%-70% adds in this container A with content, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, ethanol in this container A is filtered, the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container C;
(3) with aqueous extract in this container B and the alcoholic extract mix homogeneously in the container C, natural sedimentation, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
Above-mentioned papermulberry extract can be controlled tinea.
But above-mentioned papermulberry extract curing cancers.
Above-mentioned papermulberry extract can be made into immune food, but obeys building body for a long time, strengthens body immunity, and function of health care is arranged.
Do the bath lotion bathing with above-mentioned papermulberry extract, the effect of sterilizing and itch-relieving is arranged, strengthen skin immunization power, can make the bright and clean health of skin.
The present invention is with respect to the beneficial effect of prior art: adopts the papermulberry extract of this preparation method gained thoroughly to have treated tinea, has short treating period, rapid-action, advantage such as method is simple, and can also be to the cancer patient with better curative effect is arranged.
[specific embodiment]
The preparation method of papermulberry extract of the present invention may further comprise the steps:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, as adopts 50 microns filter, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) again with the aqueous extract natural sedimentation of this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry at normal temperatures or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
The preparation method of above-mentioned papermulberry extract can also may further comprise the steps in order to the preparation of below method:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, with content is that the ethanol of 50%-70% adds in this container A, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, the ethanol in this container A is filtered, as adopt 50 microns filter, the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container B;
(2) again with the alcoholic extract natural sedimentation in this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry at normal temperatures or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
The preparation method of above-mentioned papermulberry extract can also may further comprise the steps in order to the preparation of below method:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, as adopts 50 microns filter, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) be that the ethanol of 50%-70% adds in this container A with content, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, ethanol in this container A is filtered, the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container C;
(3) with aqueous extract in this container B and the alcoholic extract mix homogeneously in the container C, natural sedimentation, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry at normal temperatures or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
Adopt the papermulberry extract of this preparation method gained, need be after the sealing aseptic and be lower than 10 ℃ of temperature and preserve down.
Above-mentioned papermulberry extract can be controlled tinea.
Usage: smear patient's tinea (as psoriasis, tinea corporis, tinea manus and pedis, dermatitis, erythra, the dandruff) with the papermulberry extract of this preparation method gained and locate, whole tinea to be covered when smearing, medication every day 1 time, with 1 to 10 time, symptom slowly disappears, without any side effects, the thorough cancellation of tinea is never recurred.
Clinical trial: cured cureless tinea of many more than ten years with the papermulberry extract of this preparation method gained.
But above-mentioned papermulberry extract curing cancers.
Usage: for oral administration or be decocted in water for oral dose (material that need not add other) with the papermulberry extract of this preparation method gained, to the cancer patient with better curative effect and positive effect are arranged.
Above-mentioned papermulberry extract can be made into immune food, as makes the food that is about 1 gram as the weight of pill, and obey once every day, and each two, but obey building body for a long time, strengthen body immunity, function of health care is arranged.
Above-mentioned papermulberry extract is done bath lotion, uses its bathing every day, and the effect of sterilizing and itch-relieving is arranged, and strengthens skin immunization power, can make the bright and clean health of skin.
The above only is preferred embodiment of the present invention, and all equalizations of being done with claim scope of the present invention change and modify, and all should belong to the covering scope of claim of the present invention.
Claims (7)
1. the preparation method of papermulberry extract is characterized in that: may further comprise the steps:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) again with the aqueous extract natural sedimentation of this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
2. the preparation method of papermulberry extract according to claim 1 is characterized in that: may further comprise the steps:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, with content is that the ethanol of 50%-70% adds in this container A, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, ethanol in this container A is filtered, and the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container B;
(2) again with the alcoholic extract natural sedimentation in this container B, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
3. the preparation method of papermulberry extract according to claim 1 is characterized in that: may further comprise the steps:
(1) skin of this papermulberry or leaf or stem or root are taken off, be put into after the fragmentation in the container A, water is joined in this container A, the skin of the papermulberry in this container A or leaf or stem or root are not just had by water logging, the skin of this papermulberry or leaf or stem or root soak time in water is 12 hours to 24 hours, with the water filtration in this container A, the elimination foreign material obtain the skin of papermulberry or the aqueous extract of leaf or stem or root in another container B;
(2) be that the ethanol of 50%-70% adds in this container A with content, the skin of the papermulberry in this container A or leaf or stem or root are just flooded by ethanol, the skin of this papermulberry or leaf or stem or root soak time in ethanol is 12 hours to 24 hours, ethanol in this container A is filtered, the elimination foreign material obtain the skin of papermulberry or the alcoholic extract of leaf or stem or root in another container C;
(3) with aqueous extract in this container B and the alcoholic extract mix homogeneously in the container C, natural sedimentation, get clear liquor, utilize boulton process to obtain the concentrate of papermulberry or obtain powder or obtain powder or concentrate with spray drying method with freeze-drying, it is the extract of papermulberry, this extract can be directly medicinal, and also available this is made various preparations for raw material.
4. according to the purposes of each described papermulberry extract of claim 1 to 3, it is characterized in that: described papermulberry extract can be controlled tinea.
5. according to the purposes of each described papermulberry extract of claim 1 to 3, it is characterized in that: but described papermulberry extract curing cancers.
6. according to the purposes of each described papermulberry extract of claim 1 to 3, it is characterized in that: described papermulberry extract can be made into immune food, but obeys building body for a long time, strengthens body immunity, and function of health care is arranged.
7. according to the purposes of each described papermulberry extract of claim 1 to 3, it is characterized in that: do the bath lotion bathing with described papermulberry extract, the effect of sterilizing and itch-relieving is arranged, strengthen skin immunization power, can make the bright and clean health of skin.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610124141XA CN1994374B (en) | 2006-12-11 | 2006-12-11 | Preparation method of papermulberry extract |
| PCT/CN2007/003515 WO2008071075A1 (en) | 2006-12-11 | 2007-12-10 | A process for preparation of extract of broussonetia papyritera and the use thereof in manufacture of a medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610124141XA CN1994374B (en) | 2006-12-11 | 2006-12-11 | Preparation method of papermulberry extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1994374A true CN1994374A (en) | 2007-07-11 |
| CN1994374B CN1994374B (en) | 2012-02-29 |
Family
ID=38249630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200610124141XA Expired - Fee Related CN1994374B (en) | 2006-12-11 | 2006-12-11 | Preparation method of papermulberry extract |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN1994374B (en) |
| WO (1) | WO2008071075A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102121170A (en) * | 2011-01-27 | 2011-07-13 | 浙江农林大学 | Preparation of effect component fibers of edgoworthia chriysantha lind and application thereof |
| CN102188489A (en) * | 2010-03-04 | 2011-09-21 | 天阳制纸(株) | Composition containing fructus broussonetiae extract for strengthening immune function |
| CN107307006A (en) * | 2017-07-13 | 2017-11-03 | 徐星桥 | Suppress the method for aspergillus versicolor using paper mulberry milk manufactured goods |
| CN108904395A (en) * | 2018-09-21 | 2018-11-30 | 贺文娟 | A kind of whitening mask |
| CN109700716A (en) * | 2019-01-26 | 2019-05-03 | 云南农业大学 | A kind of application of paper mulberry, fresh fruit extraction process of active component and extract |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113181240B (en) * | 2021-06-18 | 2022-04-01 | 广东药科大学 | Application of broussonetia papyrifera root bark in preparation of medicine for treating atopic dermatitis |
| CN115645458A (en) * | 2022-10-10 | 2023-01-31 | 黄河科技学院 | Application of broussonetia papyrifera leaf extract in preparation of psoriasis treatment medicine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067574C (en) * | 1998-07-23 | 2001-06-27 | 张侠 | Traditional Chinese medicine preparation for treating leuoderma |
| US6737439B2 (en) * | 2001-08-07 | 2004-05-18 | The Board Of Trustees Of The University Of Illinois | Aromatase inhibitors from Broussonetia papyrifera |
-
2006
- 2006-12-11 CN CN200610124141XA patent/CN1994374B/en not_active Expired - Fee Related
-
2007
- 2007-12-10 WO PCT/CN2007/003515 patent/WO2008071075A1/en active Application Filing
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188489A (en) * | 2010-03-04 | 2011-09-21 | 天阳制纸(株) | Composition containing fructus broussonetiae extract for strengthening immune function |
| CN102121170A (en) * | 2011-01-27 | 2011-07-13 | 浙江农林大学 | Preparation of effect component fibers of edgoworthia chriysantha lind and application thereof |
| CN102121170B (en) * | 2011-01-27 | 2014-10-08 | 浙江农林大学 | Preparation of effect component fibers of edgoworthia chriysantha lind and application thereof |
| CN107307006A (en) * | 2017-07-13 | 2017-11-03 | 徐星桥 | Suppress the method for aspergillus versicolor using paper mulberry milk manufactured goods |
| CN107307006B (en) * | 2017-07-13 | 2020-04-10 | 徐星桥 | Method for inhibiting aspergillus versicolor by using paper mulberry milk product |
| CN108904395A (en) * | 2018-09-21 | 2018-11-30 | 贺文娟 | A kind of whitening mask |
| CN109700716A (en) * | 2019-01-26 | 2019-05-03 | 云南农业大学 | A kind of application of paper mulberry, fresh fruit extraction process of active component and extract |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008071075A1 (en) | 2008-06-19 |
| CN1994374B (en) | 2012-02-29 |
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Effective date of registration: 20090123 Address after: Guangdong city of Dongguan province Dongcheng District Tongsha water Ling Xi Si Xiang post encoding: 523127 Applicant after: Dongguan City Zhengxing Electric Appliance Co., Ltd. Address before: Lane two, Lane eight, Qi Hua Keng Cun, Lixin management area, Guangdong, Dongguan Province, China: 523008. Applicant before: Shi Yu |
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