CN1977932A - Tiaogu tablet composition and its production process - Google Patents
Tiaogu tablet composition and its production process Download PDFInfo
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- CN1977932A CN1977932A CN 200510122960 CN200510122960A CN1977932A CN 1977932 A CN1977932 A CN 1977932A CN 200510122960 CN200510122960 CN 200510122960 CN 200510122960 A CN200510122960 A CN 200510122960A CN 1977932 A CN1977932 A CN 1977932A
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Abstract
The present invention relates to a prescription of Chinese medicine Tiaogupian tablet for curing traumatic injury and its production process. Said prescription includes 20 Chinese medicinal materials of drynaria root, calcined pyrite, wingless cockroach, carthamus flower, notoginseng, astragalus root and others. Said invention also provides the concrete steps of its production process.
Description
[technical field]
The invention relates to a kind of Chinese patent medicine that from pure Chinese medicine, extract, be meant a kind of prescription and production technology thereof of jumping osteocomma especially.
[background technology]
Fracture is a more incidental slight illness in the daily life; there are the characteristics that misery is big, healing is slow, stadium is long usually in patient after the fracture; clinical in pain, afunction, lopsided pseudarthrosis phenomenon, abnormal movement, bony crepitus and subcutaneous ecchymosis ooze out and are characteristics.The method of clinical treatment fracture mainly contains three kinds at present, and first kind is that the reuse plaster fixation made its normal healing after fracture was carried out manual reset, and this method patient suffering is big, and treatment time is quite long; Second kind for serious fracture patient, then need operative treatment, fracture is fixed with steel nail, steel plate, but fracture itself is a kind of damage, adds the execution of operation, certainly will damage more local organization, cause the resistance of tissue to descend, if postoperative generation wound infection, even become osteomyelitis, increase the patient suffering more; The third is a Drug therapy, Drug therapy comprises oral medicine and medicine for external use, present medicine is that cure rate is low, the course of treatment long, curative effect is not remarkable through the clinical practice major part, what have also has side effects, thereby the patient is under the relatively poor situation of the effect of taking medicine, must not no longer select operation, delay treatment time and increased medical expense, the most important thing is to cause great misery to the patient.
[summary of the invention]
One of technical problem to be solved by this invention is to provide a kind of instant effect, good effect, the prescription of the jumping osteocomma that treatment time is short.
Two of technology to be solved by this invention is to provide the production technology of this jumping osteocomma.
The present invention solves above-mentioned first technical problem by the following technical programs: a kind of jumping osteocomma, the scope that its raw material is formed and each raw material is formed is respectively: by weight, and Rhizoma Drynariae (stir-fry) 7-9 part, Pyritum (calcined) 3-5 part, Eupolyphaga Seu Steleophaga 3-5 part, Olibanum (stir-fry) 3-5 part, Myrrha (stir-fry) 3-5 part, Flos Carthami 1-3 part, Radix Notoginseng 3-5 part, purslane speedwell Herba 3-5 part, Sanguis Draxonis 3-5 part, Radix Astragali 7-9 part, parched with bran Fructus Aurantii 7-9 part, Radix Linderae 1-3 part, Borneolum Syntheticum 0.5-1.5 part, Semen Strychni (system) 1.5-3 part, Herba Asari 1-3 part, Rhizoma Et Radix Notopterygii 1-3 part, Radix Angelicae Pubescentis 1-3 part, Rhizoma Cibotii (stir-fry) 3-5 part, Fructus Tribuli 3-5 part, Cinnabaris (water flies) 1-3 part.
The present invention solves above-mentioned second technical problem by the following technical programs: a kind of production technology of jumping osteocomma may further comprise the steps:
(1) get except that Cinnabaris, Borneolum Syntheticum 18 the flavor Chinese medicines, clean respectively, wash, mix homogeneously is dried to moisture below 5% through 65 ℃-70 ℃;
(2) with the raw material of Chinese medicine mixture of above-mentioned mix homogeneously, be ground into 80 purpose fine powder A through cracker for medicine;
(3) get Borneolum Syntheticum and in micropulverizer, pulverize, and cross 80 eye mesh screens, standby;
(4) get above-mentioned fine powder A and Cinnabaris mix homogeneously, pulverize mixing through cracker for medicine again, and cross 100 mesh sieves, get fine powder B;
(5) fine powder B adds adjuvant, in full-automatic wet granulator, draws the wet soft material made from 70% ethanol;
(6) above-mentioned soft material is granulated in full-automatic wet granulator, and dry in boiling drier, moisture Control is below 3%;
(7) the above-mentioned dry granule of crossing is through 18 eye mesh screen granulate, mixes with the Borneolum Syntheticum of mistake 80 eye mesh screens in the above-mentioned steps (3) again;
(8) mixture in the step (7) is pressed into the plain sheet of 0.3g/ sheet in full-automatic tablet machine;
(9) plain sheet is bundled into sugar-coat after the inspection of semifinished product is qualified, promptly makes and jumps the osteocomma finished product, divides packing to get final product.
Wherein the adjuvant in the step (5) is for to be mixed by starch, dextrin, and wherein starch, dextrin weight ratio are 9: 11.
The present invention jumps the prescription of osteocomma and the advantage of production technology is: classical Chinese medicine " Ling Shu Miraculous Pivot or Divine Axis this dirty ": " meridians person, so qi and blood circulation promotion and seek negative and positive moistens muscles and bones, sharp joint also ".These have diffusing blood and stimulate the menstrual flow with Flos Carthami, Radix Notoginseng, Semen Strychni (system), Eupolyphaga Seu Steleophaga to jump osteocomma, activate meridians, the pure Chinese medicine of the knot analgesic effect that disappears is monarch drug, Olibanum be that the hot temperature of loosing is led to, can activating blood circulation to dissipate blood stasis, circulation of qi promoting is loose and is stagnated again, the Myrrha blood silt of loosing, Cinnabaris is calmed the nerves for patient's arresting convulsion, above-mentioned all medicine combinations, have subduing swelling and relieving pain, relaxing muscles and tendons to promote blood circulation, promote effects such as growth of spur, can be used for fracture, dislocation etc.
[description of drawings]
The invention will be further described in conjunction with the embodiments with reference to the accompanying drawings.
Fig. 1 is the technological process of production figure that the present invention jumps osteocomma.
[specific embodiment]
Embodiment one
By weight, get 7 parts of Rhizoma Drynariae (stir-fry), 3 parts of Pyritum (calcined)s, 3 parts of Eupolyphaga Seu Steleophagas, 3 parts of Olibanums (stir-fry), 3 parts of Myrrhas (stir-fry), 1 part on Flos Carthami, 3 parts of Radix Notoginseng, 3 parts of purslane speedwell Herbas, 3 parts of Sanguis Draxonis, 7 parts of the Radixs Astragali, 7 parts of parched with bran Fructus Aurantii, 1 part of the Radix Linderae, 0.5 part of Borneolum Syntheticum, 1.5 parts of Semen Strychni (system), 1 part of Herba Asari, 1 part of Rhizoma Et Radix Notopterygii, 1 part of Radix Angelicae Pubescentis, 3 parts of Rhizoma Cibotii (stir-fry), 3 parts of Fructus Tribulis, 1 part in Cinnabaris (water flies), totally 20 flavor Chinese crude drugs.
Production technology:
1, get except that Cinnabaris, Borneolum Syntheticum 18 the flavor Chinese medicines, clean respectively, wash, mix homogeneously is dried to moisture below 5% through 65 ℃-70 ℃;
2, with the raw material of Chinese medicine mixture of above-mentioned mix homogeneously, be ground into 80 purpose fine powder A through cracker for medicine;
3, get Borneolum Syntheticum and in micropulverizer, pulverize, and cross 80 eye mesh screens;
4, get above-mentioned fine powder A and Cinnabaris mix homogeneously, pulverize mixing through cracker for medicine again, and cross 100 mesh sieves, get fine powder B;
5, in full-automatic wet granulator, fine powder B adds the adjuvant that is mixed by starch, dextrin, and wherein starch, dextrin weight ratio are 9: 11, draws the wet soft material made from 70% ethanol;
6, above-mentioned soft material is granulated in full-automatic wet granulator, and dry in boiling drier, moisture Control is below 3%;
7, the above-mentioned dry granule of crossing is through 18 eye mesh screen granulate, mixes with 80 order Borneolum Syntheticums in the above-mentioned steps 3 again;
8, the mixture in the step 7 is pressed into the plain sheet of 0.3g/ sheet in full-automatic tablet machine;
9, plain sheet is bundled into sugar-coat after the inspection of semifinished product is qualified, promptly makes and jumps the osteocomma finished product, divides packing to get final product.
Embodiment two
By weight, get 9 parts of Rhizoma Drynariae (stir-fry), 5 parts of Pyritum (calcined)s, 5 parts of Eupolyphaga Seu Steleophagas, 5 parts of Olibanums (stir-fry), 5 parts of Myrrhas (stir-fry), 3 parts on Flos Carthami, 5 parts of Radix Notoginseng, 5 parts of purslane speedwell Herbas, 5 parts of Sanguis Draxonis, 9 parts of the Radixs Astragali, 9 parts of parched with bran Fructus Aurantii, 3 parts of the Radixs Linderae, 1.5 parts of Borneolum Syntheticums, 3 parts of Semen Strychni (system), 3 parts of Herba Asaris, 3 parts of Rhizoma Et Radix Notopterygiis, 3 parts of Radix Angelicae Pubescentiss, 5 parts of Rhizoma Cibotii (stir-fry), 5 parts of Fructus Tribulis, 3 parts in Cinnabaris (water flies), totally 20 flavor Chinese crude drugs.
Its preparation method is with above-mentioned embodiment one.
Embodiment three:
By weight, get Rhizoma Drynariae (stir-fry) 28g, Pyritum (calcined) 14g, Eupolyphaga Seu Steleophaga 14g, Olibanum (stir-fry) 14g, Myrrha (stir-fry) 14g, Flos Carthami 7g, Radix Notoginseng 14g, purslane speedwell Herba 14g, Sanguis Draxonis 14g, Radix Astragali 28g, parched with bran Fructus Aurantii 28g, Radix Linderae 7g, Borneolum Syntheticum 3.4g part, Semen Strychni (system) 10g, Herba Asari 7g, Rhizoma Et Radix Notopterygii 7g, Radix Angelicae Pubescentis 7g, Rhizoma Cibotii (stir-fry) 14g, Fructus Tribuli 14g, Cinnabaris (water flies) 7g, totally 20 flavor Chinese crude drugs.
Production technology:
1, get except that Cinnabaris, Borneolum Syntheticum 18 the flavor Chinese medicines, clean respectively, wash, mix homogeneously is dried to moisture below 5% through 65 ℃-70 ℃;
2, with the raw material of Chinese medicine mixture of above-mentioned mix homogeneously, be ground into 80 purpose fine powder A through cracker for medicine;
3, get Borneolum Syntheticum and in micropulverizer, pulverize, and cross 80 eye mesh screens;
4, get above-mentioned fine powder A and Cinnabaris mix homogeneously, pulverize mixing through cracker for medicine again, and cross 100 mesh sieves, get fine powder B;
5, in full-automatic wet granulator, fine powder B adds the adjuvant that is mixed by starch, dextrin, and wherein starch, dextrin weight ratio are 9: 11, draws the wet soft material made from 70% ethanol;
6, above-mentioned soft material is granulated in full-automatic wet granulator, and dry in boiling drier, moisture Control is below 3%;
7, the above-mentioned dry granule of crossing is through 18 eye mesh screen granulate, mixes with 80 order Borneolum Syntheticums in the above-mentioned steps 3 again;
8, the mixture in the step 7 is pressed into the plain sheet of 0.3g/ sheet in full-automatic tablet machine;
9, plain sheet is bundled into sugar-coat after the inspection of semifinished product is qualified, promptly makes and jumps the osteocomma finished product, divides packing to get final product.
In the above-mentioned preparation method, it should be noted that: 1, Olibanum, Myrrha are oil Chinese medicine, have stronger viscosity, can not pulverize, with combination dryings such as the many Chinese crude drug Radix Angelicae Pubescentis of mealiness, Radix Notoginseng after, just can be ground into fine powder; 2, Borneolum Syntheticum is to have volatile Chinese medicine, and is all volatile at normal temperatures, more can not high temperature drying, and this preparation technology adds Borneolum Syntheticum at last, has solved Borneolum Syntheticum because of volatile loss problem, has guaranteed the consumption of Borneolum Syntheticum in the prescription; 3, traditional Chinese medicine is pulverized without dried, and this preparation technology is through 65 ℃～70 ℃ high-temperature process, and the moisture Control that makes Chinese crude drug is below 5%, and Chinese Pharmacopoeia is 5%-15%.The friability of Chinese crude drug has just improved like this, thereby guarantee to be ground into 100 purpose fine powders, improved the effective ingredient dissolution rate of medicated powder greatly, the plain sheet smooth surface that simultaneously full-automatic tablet machine is pressed into, improved the uniformity of toxic component in the Chinese medicines such as Semen Strychni, Sanguis Draxonis greatly, prevented that the transition of strychnine effective ingredient such as (effective ingredient of Semen Strychni) in indivedual tablets from concentrating and cause side effect.
Claims (5)
1. jump osteocomma for one kind, it is characterized in that: the scope that its raw material is formed and each raw material is formed is respectively: by weight, and Rhizoma Drynariae (stir-fry) 7-9 part, Pyritum (calcined) 3-5 part, Eupolyphaga Seu Steleophaga 3-5 part, Olibanum (stir-fry) 3-5 part, Myrrha (stir-fry) 3-5 part, Flos Carthami 1-3 part, Radix Notoginseng 3-5 part, purslane speedwell Herba 3-5 part, Sanguis Draxonis 3-5 part, Radix Astragali 7-9 part, parched with bran Fructus Aurantii 7-9 part, Radix Linderae 1-3 part, Borneolum Syntheticum 0.5-1.5 part, Semen Strychni (system) 1.5-3 part, Herba Asari 1-3 part, Rhizoma Et Radix Notopterygii 1-3 part, Radix Angelicae Pubescentis 1-3 part, Rhizoma Cibotii (stir-fry) 3-5 part, Fructus Tribuli 3-5 part, Cinnabaris (water flies) 1-3 part.
2. jumping osteocomma as claimed in claim 1, it is characterized in that: the scope that its raw material is formed and each raw material is formed is respectively: by weight, Rhizoma Drynariae (stir-fry) 28g, Pyritum (calcined) 14g, Eupolyphaga Seu Steleophaga 14g, Olibanum (stir-fry) 14g, Myrrha (stir-fry) 14g, Flos Carthami 7g, Radix Notoginseng 14g, purslane speedwell Herba 14g, Sanguis Draxonis 14g, Radix Astragali 28g, parched with bran Fructus Aurantii 28g, Radix Linderae 7g, Borneolum Syntheticum 3.4g part, Semen Strychni (system) 10g, Herba Asari 7g, Rhizoma Et Radix Notopterygii 7g, Radix Angelicae Pubescentis 7g, Rhizoma Cibotii (stir-fry) 14g, Fructus Tribuli 14g, Cinnabaris (water flies) 7g, totally 20 flavor Chinese crude drugs.
3. a production technology of jumping osteocomma is characterized in that: comprise the steps:
(1) get except that Cinnabaris, Borneolum Syntheticum 18 the flavor Chinese medicines, clean respectively, wash, mix homogeneously is dried to moisture below 5% through 65 ℃-70 ℃;
(2) with the raw material of Chinese medicine mixture of above-mentioned mix homogeneously, be ground into 80 purpose fine powder A through cracker for medicine;
(3) get Borneolum Syntheticum and in micropulverizer, pulverize, and cross 80 eye mesh screens;
(4) get above-mentioned fine powder A and Cinnabaris mix homogeneously, pulverize mixing through cracker for medicine again, and cross 100 mesh sieves, get fine powder B;
(5) in full-automatic wet granulator, fine powder B adds adjuvant, draws the wet soft material made from 70% ethanol;
(6) above-mentioned soft material is granulated in full-automatic wet granulator, and is dry in boiling drier, makes moisture Control below 3%;
(7) the above-mentioned dry granule of crossing is through 18 eye mesh screen granulate, mixes with the Borneolum Syntheticum of mistake 80 eye mesh screens in the above-mentioned steps (3) again;
(8) mixture in the step (7) is pressed into the plain sheet of 0.3g/ sheet in full-automatic tablet machine;
(9) plain sheet is bundled into sugar-coat after the inspection of semifinished product is qualified, promptly makes and jumps the osteocomma finished product, divides packing to get final product.
4. a kind of production technology of jumping osteocomma as claimed in claim 3 is characterized in that: the adjuvant in the step (5) is that starch, dextrin mix, and wherein starch, dextrin weight ratio are 9: 11.
5. a kind of production technology of jumping osteocomma as claimed in claim 3, it is characterized in that: wherein the scope of the composition of each medicine material and each composition is respectively: by weight, and Rhizoma Drynariae (stir-fry) 7-9 part, Pyritum (calcined) 3-5 part, Eupolyphaga Seu Steleophaga 3-5 part, Olibanum (stir-fry) 3-5 part, Myrrha (stir-fry) 3-5 part, Flos Carthami 1-3 part, Radix Notoginseng 3-5 part, purslane speedwell Herba 3-5 part, Sanguis Draxonis 3-5 part, Radix Astragali 7-9 part, parched with bran Fructus Aurantii 7-9 part, Radix Linderae 1-3 part, Borneolum Syntheticum 0.5-1.5 part, Semen Strychni (system) 1.5-3 part, Herba Asari 1-3 part, Rhizoma Et Radix Notopterygii 1-3 part, Radix Angelicae Pubescentis 1-3 part, Rhizoma Cibotii (stir-fry) 3-5 part, Fructus Tribuli 3-5 part, Cinnabaris (water flies) 1-3 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510122960 CN1977932A (en) | 2005-12-05 | 2005-12-05 | Tiaogu tablet composition and its production process |
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| CN 200510122960 CN1977932A (en) | 2005-12-05 | 2005-12-05 | Tiaogu tablet composition and its production process |
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| CN1977932A true CN1977932A (en) | 2007-06-13 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546985A (en) * | 2014-11-13 | 2015-04-29 | 广西昌弘制药有限公司 | Preparation method of traditional Chinese medicinal preparation capable of clearing heat, relieving sore throat and relieving pain |
| CN108685997A (en) * | 2018-07-16 | 2018-10-23 | 谢朝阳 | A kind of Chinese medicine preparation and preparation method thereof for damaging fracture |
| CN110013511A (en) * | 2018-11-09 | 2019-07-16 | 重庆涪陵李志沧中医骨伤医院有限公司 | A kind of jump bone Chinese medicine composition and its preparation and application |
-
2005
- 2005-12-05 CN CN 200510122960 patent/CN1977932A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546985A (en) * | 2014-11-13 | 2015-04-29 | 广西昌弘制药有限公司 | Preparation method of traditional Chinese medicinal preparation capable of clearing heat, relieving sore throat and relieving pain |
| CN108685997A (en) * | 2018-07-16 | 2018-10-23 | 谢朝阳 | A kind of Chinese medicine preparation and preparation method thereof for damaging fracture |
| CN110013511A (en) * | 2018-11-09 | 2019-07-16 | 重庆涪陵李志沧中医骨伤医院有限公司 | A kind of jump bone Chinese medicine composition and its preparation and application |
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