CN1972680A - 治疗或者预防高骨转换个体中骨质疏松症的方法 - Google Patents

治疗或者预防高骨转换个体中骨质疏松症的方法 Download PDF

Info

Publication number
CN1972680A
CN1972680A CNA2005800049712A CN200580004971A CN1972680A CN 1972680 A CN1972680 A CN 1972680A CN A2005800049712 A CNA2005800049712 A CN A2005800049712A CN 200580004971 A CN200580004971 A CN 200580004971A CN 1972680 A CN1972680 A CN 1972680A
Authority
CN
China
Prior art keywords
bone
bone resorption
purposes
serum
thing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800049712A
Other languages
English (en)
Chinese (zh)
Inventor
T·布洛姆
L·坎加斯
R·拉明陶斯塔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hormos Medical Ltd
Original Assignee
Hormos Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hormos Medical Ltd filed Critical Hormos Medical Ltd
Publication of CN1972680A publication Critical patent/CN1972680A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA2005800049712A 2004-02-23 2005-01-19 治疗或者预防高骨转换个体中骨质疏松症的方法 Pending CN1972680A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/783,092 2004-02-23
US10/783,092 US20050187302A1 (en) 2004-02-23 2004-02-23 Method for treatment or prevention of osteoporosis in individuals with high bone turnover

Publications (1)

Publication Number Publication Date
CN1972680A true CN1972680A (zh) 2007-05-30

Family

ID=34861145

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800049712A Pending CN1972680A (zh) 2004-02-23 2005-01-19 治疗或者预防高骨转换个体中骨质疏松症的方法

Country Status (11)

Country Link
US (1) US20050187302A1 (https=)
EP (1) EP1718287A1 (https=)
JP (1) JP2007523209A (https=)
CN (1) CN1972680A (https=)
AU (1) AU2005215173A1 (https=)
BR (1) BRPI0507912A (https=)
CA (1) CA2557116A1 (https=)
MX (1) MXPA06009549A (https=)
NO (1) NO20064007L (https=)
RU (1) RU2006133903A (https=)
WO (1) WO2005079776A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
EP1986655A4 (en) * 2006-02-06 2009-12-23 Tethys Bioscience Inc MARKERS ASSOCIATED WITH OSTEOPOROSIS AND METHODS OF USE
CA2677861C (en) * 2007-02-14 2015-05-19 Hormos Medical Ltd. Method for the preparation of therapeutically valuable triphenylbutene derivatives
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
JP5010034B2 (ja) * 2007-12-28 2012-08-29 エフ．ホフマン−ラ ロシュ アーゲー 生理学的状態の評価
CN102690347B (zh) * 2012-05-18 2014-06-25 北京北方生物技术研究所 分离i型前胶原氨基末端肽的方法
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9418067D0 (en) * 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause

Also Published As

Publication number Publication date
JP2007523209A (ja) 2007-08-16
EP1718287A1 (en) 2006-11-08
NO20064007L (no) 2006-09-21
WO2005079776A1 (en) 2005-09-01
US20050187302A1 (en) 2005-08-25
AU2005215173A8 (en) 2009-09-24
MXPA06009549A (es) 2007-04-10
AU2005215173A1 (en) 2005-09-01
BRPI0507912A (pt) 2007-07-10
CA2557116A1 (en) 2005-09-01
RU2006133903A (ru) 2008-03-27

Similar Documents

Publication Publication Date Title
Sato et al. Emerging therapies for the prevention or treatment of postmenopausal osteoporosis
CN1390126B (zh) 选择性雌激素受体调节剂在制备用于治疗或降低肥胖症发展危险性的药物中的用途
Santen Inhibition of aromatase: insights from recent studies
Clemett et al. Raloxifene: a review of its use in postmenopausal osteoporosis
Simoncini et al. Raloxifene acutely stimulates nitric oxide release from human endothelial cells via an activation of endothelial nitric oxide synthase
Mann et al. 17α-Estradiol prevents ovariectomy-mediated obesity and bone loss
Robertson ICI 182,780 (Fulvestrant™)–the first oestrogen receptor down-regulator–current clinical data
US4894373A (en) Antiestrogens and their use in treatment of menopause and osteoporosis
US4310523A (en) Combined antiestrogens and antigonadotropically effective antiandrogens for the prophylaxis and therapy of hyperplasia of the prostate
Balfour et al. Raloxifene
JP6532754B2 (ja) エストロゲン関連疾患を治療するまたは予防するための方法
JP2018115213A (ja) アンドロゲン欠乏症を治療するための併用療法
JP2005524630A (ja) エストロゲン受容体を介する軟骨破壊の抑制
JP2015508825A5 (https=)
Evans et al. Tissue-selective actions of estrogen analogs
Lee et al. The 2024 Guidelines for Osteoporosis-Korean Society of Menopause: Part II
Bjarnason et al. Raloxifene reduces atherosclerosis: studies of optimized raloxifene doses in ovariectomized, cholesterol‐fed rabbits
CN1972680A (zh) 治疗或者预防高骨转换个体中骨质疏松症的方法
US20080032959A1 (en) Estrogen Receptor Modulators
Yaşar et al. Clomiphene citrate–induced severe hypertriglyceridemia
MX2007000741A (es) Composiciones que comprenden inhibidores de la 5-alfa-reductasa y moduladores de receptores de estrogeno selectivos (serms) y metodos de uso de los mismos.
JP2002541223A (ja) エストロゲンレセプター及び骨
EA010593B1 (ru) Применение антипрогестинов для индукции апоптоза клетки
Gennari et al. Lasofoxifene: Evidence of its therapeutic value in osteoporosis
Josse Roles for estrogen in bone loss and arthralgia during aromatase inhibitor treatment

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication