CN1969960A - Pharmaceutical composition for treating acne and application method thereof - Google Patents
Pharmaceutical composition for treating acne and application method thereof Download PDFInfo
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- CN1969960A CN1969960A CN 200610144319 CN200610144319A CN1969960A CN 1969960 A CN1969960 A CN 1969960A CN 200610144319 CN200610144319 CN 200610144319 CN 200610144319 A CN200610144319 A CN 200610144319A CN 1969960 A CN1969960 A CN 1969960A
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Abstract
Disclosed is a pharmaceutical composition for treating acne and method of use, wherein the the composition comprises gingko, dahurian angelica root, honeysuckle flower, capsule of weeping forsythia, licorice root, wild chrysanthemum flower, sulfur and antibiotic medicaments. The method of use consists of removing sebaceous gland deposits by means of physical methods, then cleaning the wounds with hydrogen peroxide.
Description
One, technical field: the present invention relates to medicine or cosmetics technical field, in particular for the pharmaceutical composition and the implementation method thereof of treatment acne.
Two, background technology: said composition comprises Chinese medicine and antibioticses such as Semen Ginkgo, the Radix Angelicae Dahuricae, Flos Lonicerae, Fructus Forsythiae, Radix Glycyrrhizae, Flos Chrysanthemi Indici and sulfur, and the stasis of blood of getting rid of in the sebaceous gland with physical method earlier before the dispenser is amassed thing, the debridement of reuse hydrogen peroxide.
Semen Ginkgo belongs to expectorants, antitussives and anti-asthmatics medicine, have broad-spectrum antibiotic, eliminate the phlegm, increase effects such as capillary permeability, antiallergic, antilipemic peroxidating.
The Radix Angelicae Dahuricae belongs to the class medicine that induces sweat, and has the effect of the diffusing wind that induces sweat, understand things pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis, and can break stagnated blood, and change loses pus, goes face defect scar.
Gold silver Pittosporum heat clearing away class medicine has effects such as broad-spectrum antiseptic, antiviral, antibacterium toxin, clinically is used for the treatment of diseases such as carbuncle sore red and swollen heat pain.
Forsythia heat clearing away class medicine has effects such as antibiotic, antiinflammatory, analgesic, heart tonifying, diuresis, blood pressure lowering, the clinical carbuncle sore tumefacting virus that is used for the treatment of, and red and swollen heat pain, it is poly-to be longer than dissipation carbuncle knot especially.
Glycyrrhiza invigorating the spleen and benefiting QI class medicine has coordinating the actions of various ingredients in a prescription, separates the effect of hundred poison of drug, and the poisoning due to some drugs, food, interior metabolism product and the bacteriotoxin is all had certain Detoxication; Modern study: Radix Glycyrrhizae has adrenocortical hormone sample function, coordinates substance metabolism, and enhancing body is to the adaptive capacity of adverse circumstances, and has effects such as antiulcer, antiinflammatory, antitumor, antitussive, blood fat reducing; Oral administration, but also external.
The Herba Dendranthematis indici Pittosporum class medicine that induces sweat has the effect of dispelling wind and heat pathogens, easy liver-yang, liver heat removing and eyesight improving, heat-clearing and toxic substances removing, and clinical Chang Peiwu is used for the treatment of sore and toxic.
Sulfur belongs to the detoxifcation parasite killing, and dampness removing to stop itchin class medicine has the detoxifcation killing parasites for relieving itching, mends the effect of fiery supporing yang relieving constipation, also has the eliminating carbuncle eliminating stagnation, receives skin ulcer and holds back mouth, softening epidermis, the effect of dissolving cutin.
Application contains Semen Ginkgo, the Radix Angelicae Dahuricae, Flos Lonicerae, Fructus Forsythiae, Radix Glycyrrhizae, Flos Chrysanthemi Indici and sulfur and antibiotics is own known as the compositions of active component, but Semen Ginkgo, the Radix Angelicae Dahuricae, Flos Lonicerae, Fructus Forsythiae, Radix Glycyrrhizae, Flos Chrysanthemi Indici and sulfur and antibiotics compatibility are reported as yet as the compositions of treatment acne.
The key factor of acne morbidity is that androgen and smegma are hyperfunction, abnormal cornification of pilosebaceous duct, the effect of the multiple quasi-microorganism of pilosebaceous unit and inflammation and host's immunoreation.Struvite skin lesion such as pustule, pimple, tuberosity, acne and cyst occur, skin lesion mostly occurs at positions such as face, breast, the back ofs the body, brings the misery of the spirit and the human body to the patient, and obstinate, shows effect repeatedly, influences patient's routine work, studying and living.
The medicine of current treatment acne or cosmetics kind are a lot, but all have unsatisfactory part in various degree, and be long as the course of treatment, cure rate is low, relapse rate is high and expense is all very expensive.
Three, summary of the invention: in order to overcome the shortcoming and defect of existing Retinoids, Retin-A, Renova, Accutane, the invention provides a kind of compositions, said composition is with the Semen Ginkgo expectorant cough suppressant and anti-asthmatic, and broad-spectrum is antibiotic, increase capillary permeability, antiallergic, antilipemic peroxidating etc. act as the master.Be aided with the Radix Angelicae Dahuricae induce sweat diffusing wind, understand things pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis, broken stagnated blood is changed and is lost pus, goes effect such as face defect scar.The Flos Lonicerae heat clearing away, the effect of diseases such as broad-spectrum antiseptic, antiviral, antibacterium toxin and treatment carbuncle sore red and swollen heat pain.The Fructus Forsythiae heat clearing away, antibiotic, antiinflammatory, analgesic, heart tonifying, diuresis, blood pressure lowering, treatment carbuncle sore tumefacting virus, red and swollen heat pain and be longer than the poly-effect of dissipation carbuncle knot.More have Radix Glycyrrhizae to play coordinating the actions of various ingredients in a prescription, separate hundred poison of drug, separate metabolism toxin and bacteriotoxic effect, its adrenocortical hormone sample function works to promote the performance drug effect to other medicines, and antagonism can not occur; And sulfur eliminating carbuncle eliminating stagnation, receive skin ulcer and hold back mouth, softening epidermis, the effect of dissolving cutin.
Because the result of broad research, the inventor has found the novel combination of Semen Ginkgo, the Radix Angelicae Dahuricae, Flos Lonicerae, Fructus Forsythiae, Radix Glycyrrhizae, Flos Chrysanthemi Indici and sulfur and antibiotics, for the treatment acne synergism is arranged, this synergism makes all medicines give full play to effect, and shortened the course of treatment, cure rate improves, relapse rate descends, and has cosmetic result concurrently, is convenient to clinical using, have no side effect, wherein the preferred enoxacin of antibiotics, ciprofloxacin, lincomycin, clindamycin.
The stasis of blood of getting rid of in the sebaceous gland with physical method (as: the air negative pressure device evenly pushes apparatus etc.) earlier before dispenser is amassed thing, so that medicine is better played effectiveness; Most of aerobe is killed in the hydrogen peroxide debridement of reuse pharmacopeia normal concentration earlier, to strengthen the effect of medicine.
The invention provides the pharmaceutical composition that is used for the treatment of acne, it comprises Semen Ginkgo, the Radix Angelicae Dahuricae, Flos Lonicerae, Fructus Forsythiae, Radix Glycyrrhizae, Flos Chrysanthemi Indici and sulfur as active princlple, respectively distinguishing the flavor of in the compositions, each medical material market is all available at home for medical material, and its extract also has the professional production manufacturer production.
The present invention respectively distinguishes the flavor of Chinese medicine can be with its extract as raw material, by the present invention's Chinese medicine extract effective dose of respectively distinguishing the flavor of, with whole crude drug is by weight ratio: Semen Ginkgo: 20---50g; The Radix Angelicae Dahuricae: 20---50g; Flos Lonicerae: 15---50g; Fructus Forsythiae: 15---50g; Radix Glycyrrhizae: 20---50g; Flos Chrysanthemi Indici: 15---50g; Sulfur: 2---12g; Antibiotics is by weight ratio: enoxacin: 0.3---3g; Ciprofloxacin: 0.1---3g; Lincomycin: 0.2---5g; Clindamycin: 0.1---3g.
Compositions of the present invention can be pressed the dispenser of series preparation form, for example: inuncts, powder, lotion, unguentum, stick agent, powder, mix and prepare with known drug carrier, adjuvant and additive, also can make tablet, powder earlier, add relevant carriers again when using and use, be prepared by usual way.
Advantage of the present invention is, compositions has significant effect to the treatment acne, and the compositions each component has good synergism, rapid-action, short treating period, cost of drugs is low, cure rate is high, and relapse rate is low, have cosmetic result, no incompatibility concurrently, have no adverse reaction and toxic and side effects sufficient raw.
Be described in further detail the present invention below by reference example:
The stasis of blood that following embodiment gets rid of in the sebaceous gland with physical method earlier before dispenser is amassed thing, the hydrogen peroxide debridement of reuse pharmacopeia normal concentration.
Embodiment 1: prescription: (by whole crude drug)
Semen Ginkgo: 30g; The Radix Angelicae Dahuricae: 30g;
Flos Lonicerae: 20g; Fructus Forsythiae: 20g;
Radix Glycyrrhizae: 30g; Flos Chrysanthemi Indici: 25g;
Each medicine of prescription is morcelled mixing be immersed among the 75% ethanol 500ml, soak 7 days after-filtration, make tincture, wipe the affected part every day outward 3 times, general 7 days produce effects can be cured in 20 days.
Embodiment 2: prescription: (by whole crude drug)
Semen Ginkgo: 30g; The Radix Angelicae Dahuricae: 30g;
Flos Lonicerae: 20g; Fructus Forsythiae: 20g;
Radix Glycyrrhizae: 30g; Flos Chrysanthemi Indici: 25g;
Sulfur: 8g.
Each medicine of prescription is standby after purifying, use Shi Jiawu times of weight portion eliminating cold for resuscitation water, sterile gauze is immersed in the liquid medicine, the gauze that will soak liquid medicine again sticks on affected part, and each 20-30 minutes, every day 3 times.Compositions of the present invention is used checking through over one hundred example, effective percentage 100%, and cure rate is more than 95%.
Embodiment 3: prescription: (by whole crude drug)
Semen Ginkgo: 30g; The Radix Angelicae Dahuricae: 30g;
Flos Lonicerae: 20g; Fructus Forsythiae: 20g;
Radix Glycyrrhizae: 30g; Flos Chrysanthemi Indici: 25g;
Above medicine adds clindamycin 1g after purifying, Mel is an amount of, makes unguentum, and when using, on disease damage face, every day, affected part of exterior coating was 3 times with paste application, and general 5 days produce effects can be cured in 15 days.
Embodiment 4: prescription: (by whole crude drug)
Semen Ginkgo: 30g; The Radix Angelicae Dahuricae: 30g;
Flos Lonicerae: 20g; Fructus Forsythiae: 20g;
Radix Glycyrrhizae: 30g; Flos Chrysanthemi Indici: 25g;
Sulfur: 8g.
Above medicine adds ciprofloxacin 1.5g after purifying, Mel is an amount of, makes unguentum, and when using, on disease damage face, every day, affected part of exterior coating was 3 times with paste application, and general 5 days produce effects can be cured in 15 days.
Compositions of the present invention is used checking through over one hundred example, effective percentage 100%, and cure rate is more than 95%.
Claims (4)
1, a kind of pharmaceutical composition and implementation method thereof that is used for the treatment of acne is characterized in that it is made by weight ratio by following raw materials according:
Semen Ginkgo: 20---50g; The Radix Angelicae Dahuricae: 20---50g;
Flos Lonicerae: 15---50g; Fructus Forsythiae: 15---50g;
Radix Glycyrrhizae: 20---50g; Flos Chrysanthemi Indici: 15---50g;
Antibiotic: 0---5g.
Make unguentum, inuncts, lotion, powder, stick agent, powder by known pharmaceutical methods, make sheet or powder earlier after also can will medicine purifying, add relevant carriers again when using and use, described carrier comprises Mel.
Implementation method is: the stasis of blood of getting rid of in the sebaceous gland with physical method earlier before dispenser is amassed thing, the hydrogen peroxide debridement of reuse pharmacopeia normal concentration.
2, pharmaceutical composition and the implementation method thereof that is used for the treatment of acne according to claim 1 is characterized in that it also comprises sulfur, and its weight proportion is: sulfur: 2---12g.
3, pharmaceutical composition and the implementation method thereof that is used for the treatment of acne according to claim 1 and 2, it is characterized in that: it comprises more than one antibiotic.
4, pharmaceutical composition and the implementation method thereof that is used for the treatment of acne according to claim 3 is characterized in that: preferred following antibiotic and weight proportion:
(1) enoxacin: 0.3---3g;
(2) ciprofloxacin: 0.1---3g;
(3) lincomycin: 0.2---5g;
(4) clindamycin: 0.1---3g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610144319 CN1969960A (en) | 2006-12-01 | 2006-12-01 | Pharmaceutical composition for treating acne and application method thereof |
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| CN 200610144319 CN1969960A (en) | 2006-12-01 | 2006-12-01 | Pharmaceutical composition for treating acne and application method thereof |
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| CN1969960A true CN1969960A (en) | 2007-05-30 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013023338A1 (en) * | 2011-08-12 | 2013-02-21 | 甘肃普源医药科技有限公司 | Pharmaceutical composition containing honeysuckle extract and antibiotics, pharmaceutical kit, and use of honeysuckle extract for preparation of drug |
| CN104940330A (en) * | 2015-06-15 | 2015-09-30 | 郎溪县建平镇玲珑苗木种植家庭农场 | Beauty pear soup and preparation method thereof |
-
2006
- 2006-12-01 CN CN 200610144319 patent/CN1969960A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013023338A1 (en) * | 2011-08-12 | 2013-02-21 | 甘肃普源医药科技有限公司 | Pharmaceutical composition containing honeysuckle extract and antibiotics, pharmaceutical kit, and use of honeysuckle extract for preparation of drug |
| CN103732609A (en) * | 2011-08-12 | 2014-04-16 | 石家庄汉康生化药品有限公司 | Pharmaceutical composition containing honeysuckle extract and antibiotics, pharmaceutical kit, and use of honeysuckle extract for preparation of drug |
| CN103732609B (en) * | 2011-08-12 | 2016-08-24 | 石家庄汉康生化药品有限公司 | Comprise Flos Lonicerae extract and the pharmaceutical composition of antibiotic, pharmaceutical kit and the pharmaceutical applications of Flos Lonicerae extract |
| US9849145B2 (en) | 2011-08-12 | 2017-12-26 | Hankang Biochemical & Pharmaceutical Co., Ltd | Pharmaceutical composition containing honeysuckle extract and antibiotics, pharmaceutical kit, and use of honeysuckle extract for preparation of drug |
| CN104940330A (en) * | 2015-06-15 | 2015-09-30 | 郎溪县建平镇玲珑苗木种植家庭农场 | Beauty pear soup and preparation method thereof |
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