CN101011482A - Pharmaceutical compositions for the treatment of acne - Google Patents
Pharmaceutical compositions for the treatment of acne Download PDFInfo
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- CN101011482A CN101011482A CN 200610114617 CN200610114617A CN101011482A CN 101011482 A CN101011482 A CN 101011482A CN 200610114617 CN200610114617 CN 200610114617 CN 200610114617 A CN200610114617 A CN 200610114617A CN 101011482 A CN101011482 A CN 101011482A
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- treatment
- acne
- radix
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- semen momordicae
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Abstract
Disclosed is a pharmaceutical composition for treating acne, which comprises rhubarb horsetails, clove, root of red rooted saliva, citron fruit, red halloysite, baras camphor and momordica seed. The composition has the advantages of low cost, short course of treatment, higher curing rate and low recurrence rate.
Description
One, technical field: the present invention relates to medicine or cosmetics technical field, in particular for the pharmaceutical composition of treatment acne.
Two, background technology: said composition comprises Chinese medicines such as Radix Et Rhizoma Rhei, Flos Caryophylli, Radix Salviae Miltiorrhizae, Fructus Citri, Halloysitum Rubrum, Borneolum Syntheticum and Semen Momordicae.
Radix Et Rhizoma Rhei has another name called Radix Et Rhizoma Rhei, belongs to rushing down the lower class medicine, has heat and toxic materials clearing away, clearing away heat-fire, and blood circulation promoting and blood stasis dispelling, detoxifcation, antibiotic effect, internal, external haemorrhage all has tangible anastalsis, and estrogen-like effects is arranged; External can be treated seborrheic dermatitis, is the medicine commonly used of treatment pathopyretic ulcer.
The Genus Syringa Wen Han class medicine that activates yang has Wen Han to activate yang, and the effect of sterilization, skin moistening has the effect that suppresses propionibacterium acnes.
Radix Salviae Miltiorrhizae belongs to the expectorant class medicine of invigorating blood circulation, and has the effect of antiandrogen, and the effect that suppresses propionibacterium acnes is arranged, and can reduce the generation of sebum, and struvite skin lesion such as pus born of the same parents, pimple and tuberosity are had better curative effect.
Fructus Citri belongs to the class medicine of regulating the flow of vital energy, and the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, preventing phlegm from forming and stopping coughing is arranged, and the effect of antiinflammatory, antiviral, enhancing capillary resistance is arranged.
Halloysitum Rubrum belongs to the astringents medicine, but external removing dampness, granulation promoting, holds back skin ulcer.
Borneolum Syntheticum belongs to the class medicine of having one's ideas straightened out, and is used for the excess syndrome of stroke coma, conjunctival congestion and swelling pain, and skin infection swells and ache, ulcer being unable to heal etc.
Semen Momordicae has the function of detumescence, eliminating stagnation, counteracting toxic substances, is used for diseases such as carbuncle, furuncle, scrofula, hemorrhoid, innominate toxic swelling, tinea skin ulcer and arthralgia pain, trauma more.
It is own known as the compositions of active component that application contains Radix Et Rhizoma Rhei, Flos Caryophylli, Radix Salviae Miltiorrhizae, Fructus Citri, Halloysitum Rubrum, Borneolum Syntheticum and Semen Momordicae, but Radix Et Rhizoma Rhei, Flos Caryophylli, Radix Salviae Miltiorrhizae, Fructus Citri, Halloysitum Rubrum, Borneolum Syntheticum and Semen Momordicae compatibility are reported as yet as the compositions of treatment acne.
The key factor of acne morbidity is that testosterone secretion increases, and the breeding of propionibacterium acnes, then sebum secretion increases, and produces the acid thromboembolism of glandular orifice under the effect of propionibacterium acnes, struvite skin lesion such as pustule, pimple, tuberosity, acne and cyst occur, skin lesion mostly occurs at positions such as face, breast, the back ofs the body, bring the spirit and the misery of the human body to the patient, and obstinate, show effect repeatedly, influence patient's routine work, studying and living.
The medicine of current treatment acne or cosmetics kind are a lot, but all have unsatisfactory part in various degree, at the bottom of, the cure rate long as the course of treatment, relapse rate height and expense be all very expensive.
Three, summary of the invention: in order to overcome the shortcoming and defect of existing Retinoids, Retin-A, Renova, Accutane, the invention provides a kind of compositions, said composition is based on Radix Et Rhizoma Rhei clearing away heat-fire, activating blood and removing stasis, detoxifcation, hemostasis, anti-, antibacterial and estrogen-like effects; Flos Caryophylli suppresses the effect that propionibacterium acnes and skin moistening effect and Radix Salviae Miltiorrhizae suppress propionibacterium acnes and antiandrogen and treat struvite skin lesion in addition; Be aided with the Fructus Citri dispersing the stagnated live-QI to relieve the stagnation of QI, regulate the flow of vital energy, antiinflammatory, antiviral strengthens the effect of capillary resistance; The Halloysitum Rubrum removing dampness, granulation promoting is held back the effect of skin ulcer; Borneolum Syntheticum treatment skin infection swells and ache, the effect of ulcer being unable to heal, and the function of Semen Momordicae detumescence, eliminating stagnation, counteracting toxic substances.
Because the result of broad research, the inventor has found the novel combination of Radix Et Rhizoma Rhei, Flos Caryophylli, Radix Salviae Miltiorrhizae, Fructus Citri, Halloysitum Rubrum, Borneolum Syntheticum and Semen Momordicae, for the treatment acne synergism is arranged, this synergism makes all medicines give full play to effect, and shortened the course of treatment, and cure rate improves, relapse rate descends, have concurrently and whiten and the skin moistening effect, be convenient to clinical using, have no side effect.
The invention provides the pharmaceutical composition that is used for the treatment of acne, he comprises Radix Et Rhizoma Rhei, Flos Caryophylli, Radix Salviae Miltiorrhizae, Fructus Citri, Halloysitum Rubrum, Borneolum Syntheticum and Semen Momordicae as active princlple; Respectively distinguishing the flavor of in the compositions, each medical material market is all available at home for medical material, and its extract has the professional production manufacturer production.
The present invention respectively distinguishes the flavor of Chinese medicine can be with its extract as raw material, by the present invention's Chinese medicine extract effective dose of respectively distinguishing the flavor of, with whole crude drug is by weight ratio: Radix Et Rhizoma Rhei: 20-50g; Flos Caryophylli 6-30g; Radix Salviae Miltiorrhizae 20-50g; Citron 20-60g; Halloysitum Rubrum 10-30g; Borneolum Syntheticum 6-20g; Semen Momordicae 10-30g.
Compositions of the present invention can be pressed the dispenser of series preparation form, for example: inuncts, powder, lotion, unguentum, stick agent, powder, mix and prepare with known drug carrier, adjuvant and additive, also can make tablet, powder earlier, add relevant carriers again when using and use, be prepared by usual way.
Advantage of the present invention is that compositions has significant effect to the treatment acne, the compositions each component has good synergism, rapid-action, short treating period, cost of drugs is low, cure rate is high, relapse rate is low, have concurrently and whiten and the skin moistening effect, no incompatibility, have no adverse reaction and toxic and side effects sufficient raw.
Be described in further detail the present invention below by reference example:
Embodiment 1: prescription: (by whole crude drug)
Radix Et Rhizoma Rhei: 30g
Flos Caryophylli: 20g
Radix Salviae Miltiorrhizae: 30g
Citron: 35g
Halloysitum Rubrum: 25g
Borneolum Syntheticum: 10g;
The broken mixing of each medicated powder of prescription is immersed among the 75% ethanol 500ml, soaks 7 days after-filtration, make tincture, wipe the affected part every day outward 3 times, general 7 days produce effects can be cured in 20 days.
Embodiment 2: prescription: (by whole crude drug)
Radix Et Rhizoma Rhei: 30g
Flos Caryophylli: 20g
Radix Salviae Miltiorrhizae: 30g
Citron: 35g
Halloysitum Rubrum: 25g
Borneolum Syntheticum: 10g;
Semen Momordicae: 15g.
Each medicine of prescription is standby after purifying, use Shi Jiawu times of weight portion eliminating cold for resuscitation water, sterile gauze is immersed in the liquid medicine, the gauze that will soak liquid medicine again sticks on affected part, and each 20-30 minute, every day 3 times.
Compositions of the present invention is used checking through hundreds of examples, effective percentage 100%, and cure rate is more than 95%.
Claims (2)
1, a kind of pharmaceutical composition that is used for the treatment of acne is characterized in that it is made by weight ratio by following raw materials according:
Radix Et Rhizoma Rhei: 20-50g;
Flos Caryophylli: 6-30g;
Radix Salviae Miltiorrhizae: 20-50g;
Fructus Citri: 20-60g;
Halloysitum Rubrum: 10-30g;
Borneolum Syntheticum: 6-20g;
Make unguentum, inuncts, lotion, powder, stick agent by known pharmaceutical methods, make sheet or powder earlier after also can will medicine purifying, add relevant carriers again when using and use.
2, the pharmaceutical composition that is used for the treatment of acne according to claim 1 is characterized in that, it also comprises Semen Momordicae, and its weight proportion is: Semen Momordicae: 10-30g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610114617 CN101011482A (en) | 2006-11-17 | 2006-11-17 | Pharmaceutical compositions for the treatment of acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610114617 CN101011482A (en) | 2006-11-17 | 2006-11-17 | Pharmaceutical compositions for the treatment of acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101011482A true CN101011482A (en) | 2007-08-08 |
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ID=38699320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610114617 Pending CN101011482A (en) | 2006-11-17 | 2006-11-17 | Pharmaceutical compositions for the treatment of acne |
Country Status (1)
| Country | Link |
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| CN (1) | CN101011482A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420452A (en) * | 2016-09-28 | 2017-02-22 | 郭豪 | Acne treatment cell repairing liquid |
-
2006
- 2006-11-17 CN CN 200610114617 patent/CN101011482A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420452A (en) * | 2016-09-28 | 2017-02-22 | 郭豪 | Acne treatment cell repairing liquid |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20070808 |