CN1965946A - Pharmaceutical composition not only capable of treating acne but also having face-beautifying function - Google Patents
Pharmaceutical composition not only capable of treating acne but also having face-beautifying function Download PDFInfo
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- CN1965946A CN1965946A CN 200610114629 CN200610114629A CN1965946A CN 1965946 A CN1965946 A CN 1965946A CN 200610114629 CN200610114629 CN 200610114629 CN 200610114629 A CN200610114629 A CN 200610114629A CN 1965946 A CN1965946 A CN 1965946A
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- radix
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- 206010000496 acne Diseases 0.000 title claims abstract description 16
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 14
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 7
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000003814 drug Substances 0.000 claims description 27
- 210000000582 semen Anatomy 0.000 claims description 22
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 11
- 241000218628 Ginkgo Species 0.000 claims description 11
- 235000011201 Ginkgo Nutrition 0.000 claims description 11
- 235000008100 Ginkgo biloba Nutrition 0.000 claims description 11
- -1 inuncts Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 5
- 239000000969 carrier Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000006210 lotion Substances 0.000 claims description 2
- 239000002674 ointment Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 24
- 239000000203 mixture Substances 0.000 abstract description 12
- 241000213006 Angelica dahurica Species 0.000 abstract 1
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- 241000758993 Equisetidae Species 0.000 abstract 1
- 244000194101 Ginkgo biloba Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 235000009815 Momordica Nutrition 0.000 abstract 1
- 241000218984 Momordica Species 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 230000003796 beauty Effects 0.000 abstract 1
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- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 abstract 1
- 210000003296 saliva Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 9
- 239000008280 blood Substances 0.000 description 5
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- 241000186427 Cutibacterium acnes Species 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 229940055019 propionibacterium acne Drugs 0.000 description 4
- 206010040882 skin lesion Diseases 0.000 description 4
- 231100000444 skin lesion Toxicity 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010040943 Skin Ulcer Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- CKMXBZGNNVIXHC-UHFFFAOYSA-L ammonium magnesium phosphate hexahydrate Chemical compound [NH4+].O.O.O.O.O.O.[Mg+2].[O-]P([O-])([O-])=O CKMXBZGNNVIXHC-UHFFFAOYSA-L 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 231100000019 skin ulcer Toxicity 0.000 description 3
- 229910052567 struvite Inorganic materials 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- SHGAZHPCJJPHSC-UHFFFAOYSA-N Panrexin Chemical compound OC(=O)C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-UHFFFAOYSA-N 0.000 description 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
- 239000003470 adrenal cortex hormone Substances 0.000 description 2
- 230000000954 anitussive effect Effects 0.000 description 2
- 230000003266 anti-allergic effect Effects 0.000 description 2
- 230000002280 anti-androgenic effect Effects 0.000 description 2
- 230000002402 anti-lipaemic effect Effects 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 239000000051 antiandrogen Substances 0.000 description 2
- 229940124584 antitussives Drugs 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000004856 capillary permeability Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000001076 estrogenic effect Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 230000003419 expectorant effect Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
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- 210000002374 sebum Anatomy 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 206010040872 skin infection Diseases 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
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- 239000003440 toxic substance Substances 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010011732 Cyst Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
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- 208000032843 Hemorrhage Diseases 0.000 description 1
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 241000882890 Renova Species 0.000 description 1
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- 208000001435 Thromboembolism Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000001088 anti-asthma Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 239000000924 antiasthmatic agent Substances 0.000 description 1
- 239000003434 antitussive agent Substances 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
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- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
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- 229940066493 expectorants Drugs 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
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- 230000023597 hemostasis Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 description 1
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- 238000002360 preparation method Methods 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
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- 210000000952 spleen Anatomy 0.000 description 1
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- 229960003604 testosterone Drugs 0.000 description 1
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- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a pharmaceutical composition having beauty treatment effect for treating acne, which comprises rhubarb horsetails, root of red rooted saliva, dahurian angelica root, gingko, citron fruit, red halloysite, licorice root, boneol and momordica seed. The composition is effective in treating acne, and has the advantages of low cost, short course of treatment, higher curing rate, and low recurrence rate.
Description
One, technical field: the present invention relates to medicine or cosmetics technical field, in particular for the pharmaceutical composition of treatment acne and beautifying face.
Two, background technology: said composition comprises Chinese medicines such as Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Semen Ginkgo, Fructus Citri, Halloysitum Rubrum, Radix Glycyrrhizae, Borneolum Syntheticum and Semen Momordicae.
Radix Et Rhizoma Rhei has another name called Radix Et Rhizoma Rhei, belongs to rushing down the lower class medicine, has heat and toxic materials clearing away, clearing away heat-fire, and blood circulation promoting and blood stasis dispelling, detoxifcation, antibiotic effect, internal, external haemorrhage all has tangible anastalsis, and estrogen-like effects is arranged; External can be treated seborrheic dermatitis, is the medicine commonly used of treatment pathopyretic ulcer.
Radix Salviae Miltiorrhizae belongs to the expectorant class medicine of invigorating blood circulation, and has the effect of antiandrogen, and the effect that suppresses propionibacterium acnes is arranged, and can reduce the generation of sebum, and struvite skin lesion such as pus born of the same parents, pimple and tuberosity are had better curative effect.
The Radix Angelicae Dahuricae belongs to the class medicine that induces sweat, and has the effect of the diffusing wind that induces sweat, understand things pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis, and can break stagnated blood, changes and loses pus.
Semen Ginkgo belongs to expectorants, antitussives and anti-asthmatics medicine, have broad-spectrum antibiotic, eliminate the phlegm, increase effects such as capillary permeability, antiallergic, antilipemic peroxidating.
Fructus Citri belongs to the class medicine of regulating the flow of vital energy, and the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, preventing phlegm from forming and stopping coughing is arranged, and the effect of antiinflammatory, antiviral, enhancing capillary resistance is arranged.
Halloysitum Rubrum belongs to the astringents medicine, but external removing dampness, granulation promoting, holds back skin ulcer.
Glycyrrhiza invigorating the spleen and benefiting QI class medicine has coordinating the actions of various ingredients in a prescription, separates the effect of hundred poison of drug, and the poisoning due to some drugs, food, interior metabolism product and the bacteriotoxin is all had certain Detoxication; Modern study: Radix Glycyrrhizae has adrenocortical hormone sample function, coordinates substance metabolism, and enhancing body is to the adaptive capacity of adverse circumstances, and has effects such as antiulcer, antiinflammatory, antitumor, antitussive, blood fat reducing; Oral administration, but also external;
Borneolum Syntheticum belongs to the class medicine of having one's ideas straightened out, and is used for the excess syndrome of stroke coma, conjunctival congestion and swelling pain, and skin infection swells and ache, ulcer being unable to heal etc.;
Semen Momordicae has the function of detumescence, eliminating stagnation, counteracting toxic substances, is used for diseases such as carbuncle, furuncle, scrofula, hemorrhoid, innominate toxic swelling, tinea skin ulcer and arthralgia pain, trauma more.
It is own known as the compositions of active component that application contains Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Semen Ginkgo, Fructus Citri, Halloysitum Rubrum, Radix Glycyrrhizae, Borneolum Syntheticum and Semen Momordicae, but Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Semen Ginkgo, Fructus Citri, Halloysitum Rubrum, Radix Glycyrrhizae, Borneolum Syntheticum and Semen Momordicae compatibility are reported as yet as the compositions of treatment acne.
The key factor of acne morbidity is that testosterone secretion increases, and the breeding of propionibacterium acnes, then sebum secretion increases, and produces the acid thromboembolism of glandular orifice under the effect of propionibacterium acnes, struvite skin lesion such as pustule, pimple, tuberosity, acne and cyst occur, skin lesion mostly occurs at positions such as face, breast, the back ofs the body, bring the spirit and the misery of the human body to the patient, and obstinate, show effect repeatedly, influence patient's routine work, studying and living.
The medicine of current treatment acne or cosmetics kind are a lot, but all have unsatisfactory part in various degree, at the bottom of, the cure rate long as the course of treatment, relapse rate height and expense be all very expensive.
Three, summary of the invention: in order to overcome the shortcoming and defect of existing Retinoids, Retin-A, Renova, Accutane, the invention provides a kind of compositions, said composition is based on Radix Et Rhizoma Rhei clearing away heat-fire, activating blood and removing stasis, detoxifcation, hemostasis, anti-, antibacterial and estrogen-like effects; The Radix Salviae Miltiorrhizae effect that suppresses propionibacterium acnes and antiandrogen and treat struvite skin lesion in addition; With Radix Angelicae Dahuricae understand things pain-stopping, detumescence and apocenosis, broken stagnated blood, change the effect that loses pus; And the Semen Ginkgo broad-spectrum antibiotic, eliminate the phlegm, increase effects such as capillary permeability, antiallergic, antilipemic peroxidating; Be aided with Fructus Citri dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, antiinflammatory, antiviral, the effect of enhancing capillary resistance; The Halloysitum Rubrum removing dampness, granulation promoting is held back the effect of skin ulcer; Borneolum Syntheticum treatment skin infection swells and ache, the effectiveness of ulcer being unable to heal, more there is Radix Glycyrrhizae to play coordinating the actions of various ingredients in a prescription, separates hundred poison of drug, separate metabolism toxin and bacteriotoxic effect, its adrenocortical hormone sample function works to promote the performance drug effect to other medicines, and antagonism can not occur; Reach the function of Semen Momordicae detumescence, eliminating stagnation, counteracting toxic substances.
Because the result of broad research, the inventor has found the novel combination of Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Semen Ginkgo, Fructus Citri, Halloysitum Rubrum, Radix Glycyrrhizae, Borneolum Syntheticum and Semen Momordicae, for the treatment acne synergism is arranged, this synergism makes all medicines give full play to effect, and shortened the course of treatment, and cure rate improves, relapse rate descends, have concurrently and whiten and the skin moistening effect, be convenient to clinical using, have no side effect.
The invention provides the pharmaceutical composition that is used for the treatment of acne, he comprises Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Semen Ginkgo, Fructus Citri, Halloysitum Rubrum, Radix Glycyrrhizae, Borneolum Syntheticum and Semen Momordicae as active princlple; Respectively distinguishing the flavor of in the compositions, each medical material market is all available at home for medical material, and its extract also has the professional production manufacturer production.
The present invention respectively distinguishes the flavor of Chinese medicine can be with its extract as raw material, by the present invention's Chinese medicine extract effective dose of respectively distinguishing the flavor of, with whole crude drug is by weight ratio: Radix Et Rhizoma Rhei 20-50g; Radix Salviae Miltiorrhizae 20-50g; Radix Angelicae Dahuricae 20-50g; Semen Ginkgo 20-50g; Fructus Citri 20-60g; Halloysitum Rubrum 10-30g; Radix Glycyrrhizae 20-50g; Borneolum Syntheticum 6-20g; Semen Momordicae 10-35g.
Compositions of the present invention can be pressed the dispenser of series preparation form, for example: inuncts, powder, lotion, unguentum, stick agent, powder, mix and prepare with known drug carrier, adjuvant and additive, also can make tablet, powder earlier, add relevant carriers again when using and use, be prepared by usual way.
Advantage of the present invention is, compositions has significant effect to the treatment acne, the compositions each component has good synergism, rapid-action, short treating period, cost of drugs is low, cure rate is high, relapse rate is low, have concurrently and whiten and the skin moistening effect, no incompatibility has no adverse reaction and toxic and side effects sufficient raw.
Be described in further detail the present invention below by reference example:
Embodiment 1: prescription: (by whole crude drug)
Radix Et Rhizoma Rhei: 30g;
Radix Salviae Miltiorrhizae: 20g;
The Radix Angelicae Dahuricae: 20g;
Semen Ginkgo: 20g;
Fructus Citri: 50g;
Halloysitum Rubrum: 25g;
Radix Glycyrrhizae: 25g;
Borneolum Syntheticum: 8g;
Each medicine of prescription is morcelled mixing be immersed among the 75% ethanol 500ml, soak 7 days after-filtration, make tincture, wipe the affected part every day outward 3 times, general 7 days produce effects can be cured in 20 days.
Embodiment 2: prescription: (by whole crude drug)
Radix Et Rhizoma Rhei: 30g;
Radix Salviae Miltiorrhizae: 20g;
The Radix Angelicae Dahuricae: 20g;
Semen Ginkgo: 20g;
Fructus Citri: 50g;
Halloysitum Rubrum: 25g;
Radix Glycyrrhizae: 25g;
Borneolum Syntheticum: 8g;
Semen Momordicae: 20g.
Each medicine of prescription is standby after purifying, use Shi Jiawu times of weight portion eliminating cold for resuscitation water, sterile gauze is immersed in the liquid medicine, the gauze that will soak liquid medicine again sticks on affected part, and each 20-30 minute, every day 3 times.
Compositions of the present invention is used checking through hundreds of examples, effective percentage 100%, and cure rate is more than 95%.
Claims (2)
1, a kind of pharmaceutical composition that is used for the treatment of acne and beautifying face is characterized in that it is made by weight ratio by following raw materials according:
Radix Et Rhizoma Rhei: 20---50g;
Radix Salviae Miltiorrhizae: 20---50g;
The Radix Angelicae Dahuricae: 20---50g;
Semen Ginkgo: 20---50g;
Fructus Citri: 20---60g;
Halloysitum Rubrum: 10---30g;
Radix Glycyrrhizae: 20---50g;
Borneolum Syntheticum: 6---20g.
Make unguentum, inuncts, lotion, powder, stick agent by known pharmaceutical methods, make sheet or powder earlier after also can will medicine purifying, add relevant carriers again when using and use.
2, the pharmaceutical composition of treatment acne and beautifying face according to claim 1 is characterized in that, it also comprises Semen Momordicae, and its weight proportion is: Semen Momordicae: 10---35g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610114629 CN1965946A (en) | 2006-11-20 | 2006-11-20 | Pharmaceutical composition not only capable of treating acne but also having face-beautifying function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610114629 CN1965946A (en) | 2006-11-20 | 2006-11-20 | Pharmaceutical composition not only capable of treating acne but also having face-beautifying function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1965946A true CN1965946A (en) | 2007-05-23 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610114629 Pending CN1965946A (en) | 2006-11-20 | 2006-11-20 | Pharmaceutical composition not only capable of treating acne but also having face-beautifying function |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926946A (en) * | 2010-08-02 | 2010-12-29 | 陈敦华 | Drug composition for whitening skin and removing freckle and preparation method thereof |
-
2006
- 2006-11-20 CN CN 200610114629 patent/CN1965946A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926946A (en) * | 2010-08-02 | 2010-12-29 | 陈敦华 | Drug composition for whitening skin and removing freckle and preparation method thereof |
| CN101926946B (en) * | 2010-08-02 | 2011-12-28 | 陈敦华 | Drug composition for whitening skin and removing freckle and preparation method thereof |
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Effective date of registration: 20080919 Address after: Room 916, building 31203, southeast district, Zhongguancun Academy of Sciences, Beijing, China: 100086 Applicant after: Beijing Guanwuzhou Biological Scientific Institute Address before: Room 3, room 916, building 1203, southeast district, Beijing Academy of Sciences, Zhongguancun, China: 100086 Applicant before: Zhu Wei |
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