CN1965907B

CN1965907B - Chinese medicinal spray for preventing and treating cold and method for preparing same

Info

Publication number: CN1965907B
Application number: CN200610051264A
Authority: CN
Inventors: 张芝庭
Original assignee: GUIZHOU MAOJKA GROUP HOLDING CO Ltd
Current assignee: GUIZHOU SHENQI PHARMACEUTICAL CO., LTD.
Priority date: 2006-11-06
Filing date: 2006-11-06
Publication date: 2010-05-12
Anticipated expiration: 2026-11-06
Also published as: CN1965907A

Abstract

Disclosed is a Chinese medicinal mist for treating common cold, wherein the raw material formula needed for preparing 1000ml of the medicinal soup includes honeysuckle flower 200g, centipede 200g, southwest scutellaria root 100g, wild chrysanthemum flower 100g, capsule of weeping forsythia 100g, spearmint 10g, natural borneol 2g, licorice root 50g, wild chrysanthemum flower 100g, isatic root 100g and flavescent sophora root 100g. The invention also discloses the process for preparing the mist.

Description

A kind of anti-medicinal herb spray that cures cold and preparation method thereof

Technical field

The present invention relates to a kind of anti-Chinese medicine preparation that cures cold, particularly relate to a kind of anti-medicinal herb spray that cures cold of via intranasal application administration.

Background technology

Flu is the very high a kind of disease of sickness rate, the viral species that causes flu is a lot, and virus also often morphs, still there is not the very strong specific drug of specific aim at present both at home and abroad, the medicine of treatment flu is a lot of in the pharmacy, Therapeutic Method is not identical unexpectedly yet, and various medicines and Therapeutic Method have its characteristics of controlling oneself and curative effect separately, but has deficiency separately simultaneously yet.Therefore people are also developing new coldrex and Therapeutic Method targetedly, reach the better anti-effect that cures cold.

Summary of the invention

The object of the present invention is to provide a kind of anti-Chinese medicine and preparation method that cures cold, can allow people by spraying medicine at the suitable position of human body, kill cold virus and prevent its growth and breeding, reach the anti-effect that cures cold.

Technical scheme of the present invention is:

This preparation belongs to compound preparation, and its thing is levied and is, every preparation 1000ml medicinal liquid needed raw material medicine is:

Flos Lonicerae 100～300g, Herba Centipedae 100～300g, Radix Scutellariae 50～200g,

Flos Chrysanthemi Indici 50～200g, Fructus Forsythiae 50～200g, Herba Menthae 5～20g, natural Broneolum Syntheticum 1～3g, Radix Glycyrrhizae 25～100g, Herba heteropappi crenatifolii 50～200g, Radix Isatidis 50～200g,

Radix Sophorae Flavescentis 50～200g.

The composition of raw materials of optimizing is:

Flos Lonicerae 200g, Herba Centipedae 200g, Radix Scutellariae 100g,

Flos Chrysanthemi Indici 100g, Fructus Forsythiae 100g, Herba Menthae 10g, natural Broneolum Syntheticum 2g, Radix Glycyrrhizae 50g,

Herba heteropappi crenatifolii 100g, Radix Isatidis 100g, Radix Sophorae Flavescentis 100g.

Used medical material is all on the books at " Chinese medicine voluminous dictionary " in the above-mentioned prescription: Flos Lonicerae, and (seeing " Chinese medicine voluminous dictionary " the 403rd page) is the caprifoliaceae plant alabastrum of Radix Ophiopogonis, sweet in the mouth is cold in nature, and heat clearing away, antidotal effect are arranged; Herba Centipedae (seeing " Chinese medicine voluminous dictionary " the 2400th page) is the wounded in the battle herb of feverfew Myriogyne minuta, acrid in the mouth, temperature, sharp nine orifices, stuffy nose relieving gas, cough-relieving arranged, eliminate the phlegm, antiasthmatic effect; Radix Scutellariae (seeing " Chinese medicine voluminous dictionary " the 2017th page) has another name called the Yunnan Radix Scutellariae, is the root of labiate Radix Scutellariae, and bitter in the mouth is cold, and the removing the relative excess fire is arranged, and removes hyther; Flos Chrysanthemi Indici (seeing " Chinese medicine voluminous dictionary " the 2144th page) is the head inflorescence of feverfew chrysanthemum, and bitter in the mouth, cold have wind and heat dispersing, the subduing swelling and detoxicating effect; Fructus Forsythiae (seeing " Chinese medicine voluminous dictionary " the 1111st page) is the fruit of Oleaceae plant Fructus Forsythiae, and bitter in the mouth is cool in nature, and heat clearing away, antidotal effect are arranged; Herba Menthae (seeing " Chinese medicine voluminous dictionary " the 2648th page) is herb or the leaf of labiate Herba Menthae, and acrid in the mouth is cool in nature, and dispelling wind, heat radiation, Detoxication are arranged; Natural Broneolum Syntheticum (see the Chinese medicine voluminous dictionary " the 951st page) is the processed goods of Borneolum Syntheticum plant Borneolum Syntheticum resin, acrid in the mouth, cold, logical all keys are arranged, the stagnated fire of loosing, removing nebula makes eye bright, the reducing swelling and alleviating pain effect; Radix Glycyrrhizae (seeing " Chinese medicine voluminous dictionary " the 567th page) is the root of glycyrrhizic legume and root stock, and sweet in the mouth, property put down, have and the effect of middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription; Herba heteropappi crenatifolii (seeing " Chinese medicine voluminous dictionary " the 2485th page) is the herb of feverfew knuckle-tooth Canis familiaris L. flower, and bitter in the mouth is cold in nature, and the effect of detoxicating, relieving inflammation, cough-relieving is arranged; Radix Isatidis (seeing " Chinese medicine voluminous dictionary " the 1250th page) is the root of cruciferae isatis and careless Folium Isatidis, and bitter in the mouth is cold in nature, and heat clearing away, antidotal effect are arranged; Radix Sophorae Flavescentis (seeing " Chinese medicine voluminous dictionary " the 1283rd page) is the root of leguminous plant Radix Sophorae Flavescentis, and bitter in the mouth is cold in nature, and the effect of heat clearing away, dampness is arranged.

Spray preparing process of the present invention:

Getting Herba Menthae, Flos Lonicerae, to collect distillate with steam distillation standby; Medicinal residues and Flos Chrysanthemi Indici, Herba Centipedae, Radix Scutellariae, Fructus Forsythiae, Radix Glycyrrhizae, Herba heteropappi crenatifolii, Radix Isatidis, Radix Sophorae Flavescentis decoct with water secondary, and gradation filters, merging filtrate, and be concentrated into to the clear paste of 50～80 ℃ of following relative densities 1.25～1.30, put cold.Add 95% ethanol and make the alcohol amount that contains of filtrate reach 75%, stir, placed 24 hours, filter, get supernatant and add 5% sodium bicarbonate adjusting pH value to 6.5～7.5.Left standstill 12 hours, and filtered, filtrate recycling ethanol adds standby distillate to there not being the ethanol flavor, adds the natural Broneolum Syntheticum 1～3g mixing with ethanol dilution, adds water to ormal weight, with the medicinal liquid packing, and sterilization, promptly.

Beneficial effect of the present invention is:

1, preparation of the present invention has the effect that suppresses and kill to cold virus;

2, the nasal spray administration absorbs soon bioavailability height, the about 150cm of nasal cavity area ², blood vessel is very abundant under the mucosa, and there is the minute cilia motion in the nose breathing road, further increases the effective area of drug absorption, makes medicine can enter the nasal cavity histiocyte rapidly;

3, the granule medicine that partly is inhaled into also has killing action to the pathogenic bacteria that enters lung;

4, side effect is little, and is safe and reliable.

The using method of medicine is: medicinal herb spray of the present invention is packed in the medical vaporizer, every side nasal cavity of hydro-peening in evening and nasopharynx part, push 1～2 time, after 2～3 minutes, sniff the unabsorbed unnecessary medicinal liquid of nasopharynx part, it is external to spue from the oral cavity, reaches the purpose of cleaning, flu epidemic season and common cold initial stage, every day, hydro-peening was 2～3 times, and method is the same.

Compared with the prior art, the present invention has convenient drug administration, treatment and anti-respond well in advance, and advantage such as medicament is easy to make, and is with low cost can be used for the anti-pre-and treatment of headache, cough and tracheitis that flu is caused, is suitable for all kinds of crowds' uses.

The specific embodiment

Embodiment 1:

It is standby with steam distillation collection distillate 200ml to get Herba Menthae 5～20g, Flos Lonicerae 100～300g; Medicinal residues and Flos Chrysanthemi Indici 50～200g, Herba Centipedae 100～300g, Radix Scutellariae 50～200g, Fructus Forsythiae 50～200g, Radix Glycyrrhizae 25～100g, Herba heteropappi crenatifolii 50～200g, Radix Isatidis 50～200g, Radix Sophorae Flavescentis 50～200g decocts with water secondary, gradation filters, merging filtrate, and be concentrated into to the clear paste of 50～80 ℃ of following relative densities 1.25～1.30, place cooling, stir and add 95% ethanol and make the alcohol amount that contains of filtrate reach 75%, placed filtration 24 hours, filtrate adds 5% sodium bicarbonate adjusting pH value to 6.5～7.5, left standstill 12 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor, add standby distillate 200ml, add natural Broneolum Syntheticum mixing, add water to 1000ml, the medicinal liquid packing with an amount of ethanol dilution, sterilization, promptly.

Embodiment 2:

The composition of raw materials of optimizing is to get Herba Menthae 10g, and it is standby that Flos Lonicerae 200g collects distillate 200ml with the steam distillation, medicinal residues and Flos Chrysanthemi Indici 100g, Herba Centipedae 200g, Radix Scutellariae 100g, Fructus Forsythiae 100g, Radix Glycyrrhizae 50g, Herba heteropappi crenatifolii 100g, Radix Isatidis 100g, Radix Sophorae Flavescentis 100g decocts with water secondary, gradation filters, merging filtrate, and be concentrated into to the clear paste of 50～80 ℃ of following relative densities 1.28, put cold, stir and add 95% ethanol and make the alcohol amount that contains of filtrate reach 75%, placed filtration 24 hours, filtrate adds 5% sodium bicarbonate adjusting pH value to 6.5～7.5, left standstill 12 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor, add standby distillate 200ml, add natural Broneolum Syntheticum 2g mixing, add water to 1000ml, the medicinal liquid packing with an amount of ethanol dilution, sterilization, promptly.

Claims

1. anti-medicinal herb spray that cures cold is characterized in that every preparation 1000ml medicinal liquid needed raw material medicine is:

Flos Lonicerae 100～300g, Herba Centipedae 100～300g, Radix Scutellariae 50～200g, Flos Chrysanthemi Indici 50～200g, Fructus Forsythiae 50～200g, Herba Menthae 5～20g, natural Broneolum Syntheticum 1～3g, Radix Glycyrrhizae 25～100g, Herba heteropappi crenatifolii 50～200g, Radix Isatidis 50～200g, Radix Sophorae Flavescentis 50～200g.

2. according to the described a kind of anti-medicinal herb spray that cures cold of claim 1, it is characterized in that the composition of raw materials of every preparation 1000ml medicinal liquid needed raw material medicine is:

Flos Lonicerae 200g, Herba Centipedae 200g, Radix Scutellariae 100g, Flos Chrysanthemi Indici 100g, Fructus Forsythiae 100g, Herba Menthae 10g, natural Broneolum Syntheticum 2g, Radix Glycyrrhizae 50g, Herba heteropappi crenatifolii 100g, Radix Isatidis 100g, Radix Sophorae Flavescentis 100g.

3. preparation is as the method for the medicinal herb spray of one of claim 1 or 2, it is characterized in that by formula proportion; get Herba Menthae; it is standby that Flos Lonicerae is collected distillate 200ml with steam distillation; medicinal residues and Flos Chrysanthemi Indici; Herba Centipedae; Radix Scutellariae; Fructus Forsythiae; Radix Glycyrrhizae; Herba heteropappi crenatifolii; Radix Isatidis; Radix Sophorae Flavescentis decocts with water secondary, and gradation filters, merging filtrate; and be concentrated into the clear paste of 50～80 ℃ of following relative densities 1.25～1.30; put coldly, stir and add 95% ethanol and make the alcohol amount that contains of filtrate reach 75%, placed 24 hours; filter; filtrate adds 5% sodium bicarbonate and regulates pH value to 6.5～7.5, leaves standstill 12 hours, filters; filtrate recycling ethanol is to there being the ethanol flavor; adds standby 200ml distillate, add the natural Broneolum Syntheticum of using ethanol dilution, and mixing; add water to 1000ml; with the medicinal liquid packing is sterilized, promptly.