CN1964733B - 肽类化合物在制备用于治疗特发性震颤的药物组合物中的用途 - Google Patents

肽类化合物在制备用于治疗特发性震颤的药物组合物中的用途 Download PDF

Info

Publication number
CN1964733B
CN1964733B CN2005800185331A CN200580018533A CN1964733B CN 1964733 B CN1964733 B CN 1964733B CN 2005800185331 A CN2005800185331 A CN 2005800185331A CN 200580018533 A CN200580018533 A CN 200580018533A CN 1964733 B CN1964733 B CN 1964733B
Authority
CN
China
Prior art keywords
purposes
group
pharmaceutical composition
tremor
prepare
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2005800185331A
Other languages
English (en)
Chinese (zh)
Other versions
CN1964733A (zh
Inventor
T·施特尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma GmbH
Original Assignee
UCB Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Pharma GmbH filed Critical UCB Pharma GmbH
Publication of CN1964733A publication Critical patent/CN1964733A/zh
Application granted granted Critical
Publication of CN1964733B publication Critical patent/CN1964733B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/03Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2005800185331A 2004-06-24 2005-06-22 肽类化合物在制备用于治疗特发性震颤的药物组合物中的用途 Expired - Fee Related CN1964733B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58208404P 2004-06-24 2004-06-24
US60/582,084 2004-06-24
PCT/EP2005/006750 WO2006000397A1 (en) 2004-06-24 2005-06-22 Novel use of peptide compounds for treating essential tremor and other tremor syndromes

Publications (2)

Publication Number Publication Date
CN1964733A CN1964733A (zh) 2007-05-16
CN1964733B true CN1964733B (zh) 2012-05-23

Family

ID=34970895

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800185331A Expired - Fee Related CN1964733B (zh) 2004-06-24 2005-06-22 肽类化合物在制备用于治疗特发性震颤的药物组合物中的用途

Country Status (19)

Country Link
US (1) US7427601B2 (enExample)
EP (1) EP1758606A1 (enExample)
JP (1) JP5038892B2 (enExample)
KR (1) KR20070034477A (enExample)
CN (1) CN1964733B (enExample)
AR (1) AR049940A1 (enExample)
AU (1) AU2005256468B2 (enExample)
BR (1) BRPI0512622A (enExample)
CA (1) CA2566301C (enExample)
EA (1) EA013592B1 (enExample)
IL (1) IL179732A0 (enExample)
MX (1) MXPA06015010A (enExample)
MY (1) MY146509A (enExample)
NO (1) NO20070423L (enExample)
NZ (1) NZ551207A (enExample)
TW (1) TWI361693B (enExample)
UA (1) UA88166C2 (enExample)
WO (1) WO2006000397A1 (enExample)
ZA (1) ZA200609021B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE327744T1 (de) * 2001-03-20 2006-06-15 Sanol Arznei Schwarz Gmbh Neue verwendung von peptidverbindungen bei der behandlung von nicht-neuropathischem entzündungsschmerz
DE60100055T2 (de) * 2001-03-21 2003-07-24 Schwarz Pharma Ag Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen
BRPI0417101A (pt) * 2003-12-02 2007-02-06 Sanol Arznei Schwarz Gmbh uso de compostos de peptìdeo para tratamento de dor neuropática central
US20100256179A1 (en) * 2004-03-26 2010-10-07 Ucb Pharma Gmbh Combination therapy for pain in painful diabetic neuropathy
EP1579858A1 (en) * 2004-03-26 2005-09-28 Schwarz Pharma Ag Novel use of peptide compounds for treating pain in painful diabetic neuropathy
US20070042969A1 (en) * 2004-03-26 2007-02-22 Srz Properties, Inc. Combination therapy for pain in painful diabetic neuropathy
CN1950101B (zh) 2004-04-16 2011-03-30 舒沃茨药物股份公司 肽化合物用于预防和治疗慢性头痛的用途
EP1604655A1 (en) * 2004-06-09 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating pain in trigeminal neuralgia
MX2007002269A (es) * 2004-08-27 2007-06-15 Sanol Arznei Schwarz Gmbh Uso novedoso de compuestos peptidos para tratar dolor por c??ncer de huesos, dolor inducido por quimioterapia y nucleosidos.
EP1642889A1 (en) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Improved synthesis scheme for lacosamide
US20060252749A1 (en) * 2005-01-28 2006-11-09 Srz Properties, Inc. Lacosamide for add-on therapy of psychosis
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
EP1754476A1 (en) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
US7902401B2 (en) * 2006-12-14 2011-03-08 Nps Pharmaceuticals, Inc. Fluorinated compounds
KR20150003925A (ko) 2006-06-15 2015-01-09 유씨비 파르마 게엠베하 상승적 항경련 효과를 갖는 약제학적 조성물
CN101466390B (zh) 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
EP2099444A4 (en) * 2006-12-14 2012-11-07 Nps Pharma Inc USE OF D-SERIN DERIVATIVES FOR THE TREATMENT OF ANTIBODIES
US7747551B2 (en) * 2007-02-21 2010-06-29 Neurovista Corporation Reduction of classification error rates and monitoring system using an artificial class
CA2774569A1 (en) 2009-09-23 2011-03-31 The University Of North Carolina At Chapel Hill Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents
US20110281808A1 (en) * 2010-05-14 2011-11-17 Allmax Nutrition Inc. Composition and Method for Increasing Pre Workout Thermogenics
US20130251813A1 (en) 2010-12-02 2013-09-26 Ucb Pharma Gmbh Formulation of lacosamide
EP2468261A1 (en) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation of lacosamide
JP2019524816A (ja) * 2016-08-11 2019-09-05 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics, Inc. てんかん性障害の処置のための方法および組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5773475A (en) * 1997-03-17 1998-06-30 Research Corporation Technologies, Inc. Anticonvulsant enantiomeric amino acid derivatives

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277825B1 (en) * 1996-07-22 2001-08-21 University Of Utah Research Foundation Use of conantokins for treating pain
US6589994B1 (en) 1996-08-30 2003-07-08 Nps Pharmaceuticals, Inc. Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound
US5866585A (en) * 1997-05-22 1999-02-02 Synchroneuron, Llc Methods of treating tardive dyskinesia using NMDA receptor antagonists
US6197764B1 (en) * 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
SI1311256T1 (sl) * 2000-08-17 2005-12-31 Teva Pharma Uporaba derivatov amidov valprojske kisline in amidov 2-valproenske kisline za zdravljenje ali preprecevanje bolecin in/ali glavobolnih motenj
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
ES2435000T3 (es) 2000-08-25 2013-12-18 Research Corporation Technologies, Inc. Aminoácidos anticonvulsionantes para el tratamiento del dolor
WO2002042256A2 (en) 2000-11-21 2002-05-30 Ucb, S.A. N-alkylated gaba compounds, processes for their preparation and their use as medicaments
EP1379236A4 (en) * 2001-02-23 2009-01-21 Ucb Sa TREATMENT OF TICS, TREMOR AND RELATED DISORDER
ATE327744T1 (de) 2001-03-20 2006-06-15 Sanol Arznei Schwarz Gmbh Neue verwendung von peptidverbindungen bei der behandlung von nicht-neuropathischem entzündungsschmerz
DE60100055T2 (de) 2001-03-21 2003-07-24 Schwarz Pharma Ag Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US6828462B2 (en) * 2001-11-07 2004-12-07 Merz Pharma Gmbh & Co. Kgaa Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
US6559293B1 (en) * 2002-02-15 2003-05-06 Transform Pharmaceuticals, Inc. Topiramate sodium trihydrate
WO2004024096A2 (en) * 2002-09-13 2004-03-25 Eisai Co., Ltd. Method of treating tremors
ES2300625T3 (es) 2002-11-18 2008-06-16 Bioprospecting Nb Inc. Peptido paralizante de musaraña para uso en terapia neuromuscular.
US20050227961A1 (en) * 2004-04-08 2005-10-13 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome
EP1604654A1 (en) * 2004-05-18 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating dyskinesia
EP1604656A1 (en) * 2004-06-09 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5773475A (en) * 1997-03-17 1998-06-30 Research Corporation Technologies, Inc. Anticonvulsant enantiomeric amino acid derivatives

Also Published As

Publication number Publication date
MY146509A (en) 2012-08-15
CN1964733A (zh) 2007-05-16
EA200700108A1 (ru) 2007-06-29
US7427601B2 (en) 2008-09-23
CA2566301A1 (en) 2006-01-05
AU2005256468A1 (en) 2006-01-05
BRPI0512622A (pt) 2008-03-25
CA2566301C (en) 2011-06-14
US20050288234A1 (en) 2005-12-29
EP1758606A1 (en) 2007-03-07
NO20070423L (no) 2007-03-22
AU2005256468B2 (en) 2010-12-09
EA013592B1 (ru) 2010-06-30
IL179732A0 (en) 2007-05-15
JP2008503533A (ja) 2008-02-07
WO2006000397A1 (en) 2006-01-05
ZA200609021B (en) 2008-04-30
TWI361693B (en) 2012-04-11
KR20070034477A (ko) 2007-03-28
UA88166C2 (ru) 2009-09-25
NZ551207A (en) 2010-07-30
MXPA06015010A (es) 2007-03-26
AR049940A1 (es) 2006-09-13
JP5038892B2 (ja) 2012-10-03
TW200603823A (en) 2006-02-01

Similar Documents

Publication Publication Date Title
CN1964733B (zh) 肽类化合物在制备用于治疗特发性震颤的药物组合物中的用途
CN100415225C (zh) 肽类化合物用于治疗非神经性炎性疼痛的新用途
JP3909842B2 (ja) 睡眠障害のためのガバペンチン類似物
CN101466390B (zh) 用于治疗难治性癫痫持续状态的肽类化合物
JP4938656B2 (ja) ジスキネジアの治療のためのペプチド化合物の新規の使用
HUP0101954A2 (hu) Kabergolin alkalmazása lábnyugtalanság szindróma kezelésére szolgáló gyógyszerkészítmény előállítására
CN1938010B (zh) 肽化合物在疼痛性糖尿病神经病变中治疗疼痛的用途
CA1267094A (en) Therapeutic drug for dementia
JP2009502914A (ja) サブスタンス関連障害を処置する方法
KARTZINEL et al. Studies with bromocriptine Part 2. Double‐blind comparison with levodopa in idiopathic parkinsonism
EP0600582A1 (en) Treatment for muscular dystrophy
AU633566B2 (en) Imidazodiazepines for the treatment of neurological symptons
US20090298895A1 (en) Use of thioproline in body weight reduction treatments
Marks et al. Epileptiform seizures with maprotiline hydrochloride
Takahashi et al. Comparison of efficacy of a new butyrophenone derivative, timiperone and perphenazine in schizophrenia by a multicentre controlled study
Mowzoon I. BASAL GANGLIA NEUROBIOLOGY (FIG. 8-1)
KR20070010168A (ko) 운동장애 치료를 위한 펩티드 화합물의 신규한 용도
CN1956715A (zh) 肽化合物用于治疗运动障碍的新用途
HK1079462A (en) Novel use of peptide compounds for treating dyskinesia

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120523

Termination date: 20130622