CN1960720A - 肽类化合物治疗肌萎缩性侧索硬化的新用途 - Google Patents

肽类化合物治疗肌萎缩性侧索硬化的新用途 Download PDF

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Publication number
CN1960720A
CN1960720A CNA2005800174638A CN200580017463A CN1960720A CN 1960720 A CN1960720 A CN 1960720A CN A2005800174638 A CNA2005800174638 A CN A2005800174638A CN 200580017463 A CN200580017463 A CN 200580017463A CN 1960720 A CN1960720 A CN 1960720A
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CN
China
Prior art keywords
lower alkyl
use according
electron
unsubstituted
aryl
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Pending
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CNA2005800174638A
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English (en)
Chinese (zh)
Inventor
T·施特尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma GmbH
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Schwarz Pharma AG
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Application filed by Schwarz Pharma AG filed Critical Schwarz Pharma AG
Publication of CN1960720A publication Critical patent/CN1960720A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2005800174638A 2004-06-09 2005-06-08 肽类化合物治疗肌萎缩性侧索硬化的新用途 Pending CN1960720A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04013636A EP1604656A1 (en) 2004-06-09 2004-06-09 Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS)
US60/578,063 2004-06-09
EP04013636.8 2004-06-09

Publications (1)

Publication Number Publication Date
CN1960720A true CN1960720A (zh) 2007-05-09

Family

ID=34925316

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800174638A Pending CN1960720A (zh) 2004-06-09 2005-06-08 肽类化合物治疗肌萎缩性侧索硬化的新用途

Country Status (14)

Country Link
US (2) US20050277596A1 (https=)
EP (2) EP1604656A1 (https=)
JP (1) JP2008501753A (https=)
CN (1) CN1960720A (https=)
AT (1) ATE544449T1 (https=)
AU (1) AU2005251459A1 (https=)
BR (1) BRPI0511875A (https=)
CA (1) CA2565102A1 (https=)
EA (1) EA200602220A1 (https=)
MX (1) MXPA06014194A (https=)
TW (1) TW200701984A (https=)
UA (1) UA87843C2 (https=)
WO (1) WO2005120476A2 (https=)
ZA (1) ZA200608594B (https=)

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JP4664924B2 (ja) * 2003-12-02 2011-04-06 ウーツェーベー ファルマ ゲーエムベーハー 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用
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EP1579858A1 (en) * 2004-03-26 2005-09-28 Schwarz Pharma Ag Novel use of peptide compounds for treating pain in painful diabetic neuropathy
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US7427601B2 (en) * 2004-06-24 2008-09-23 Schwarz Pharma Ag Method for treating tremor
PL1781276T3 (pl) * 2004-08-27 2010-11-30 Ucb Pharma Gmbh Zastosowanie związków peptydowych do leczenia bólu związanego z rakiem kości, bólu indukowanego przez chemioterapię oraz nukleozydy
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CN101466390B (zh) * 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
WO2007144195A2 (en) 2006-06-15 2007-12-21 Schwarz Pharma Ag Pharmaceutical composition with synergistic anticonvulsant effect
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CA2774569A1 (en) * 2009-09-23 2011-03-31 The University Of North Carolina At Chapel Hill Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents
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MX2013005974A (es) 2010-12-02 2013-07-29 Ucb Pharma Gmbh Formulacion de lacosamida de administracion una vez al dia.
EP2468261A1 (en) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation of lacosamide
CN109069480A (zh) 2015-12-30 2018-12-21 阿达玛斯医药公司 用于治疗与癫痫相关的病症的方法和组合物
US11278634B1 (en) 2021-02-12 2022-03-22 Extrovis Ag Stable parenteral composition of lacosamide

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Also Published As

Publication number Publication date
US20090018198A1 (en) 2009-01-15
EP1604656A1 (en) 2005-12-14
AU2005251459A1 (en) 2005-12-22
TW200701984A (en) 2007-01-16
ZA200608594B (en) 2008-04-30
CA2565102A1 (en) 2005-12-22
ATE544449T1 (de) 2012-02-15
EP1755577A2 (en) 2007-02-28
US20050277596A1 (en) 2005-12-15
EP1755577B1 (en) 2012-02-08
EA200602220A1 (ru) 2007-04-27
UA87843C2 (ru) 2009-08-25
MXPA06014194A (es) 2007-03-12
WO2005120476A3 (en) 2006-02-16
JP2008501753A (ja) 2008-01-24
US7718161B2 (en) 2010-05-18
BRPI0511875A (pt) 2008-01-15
WO2005120476A2 (en) 2005-12-22

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Application publication date: 20070509