CN1956739B - 灭活样品所含病毒的方法 - Google Patents

灭活样品所含病毒的方法 Download PDF

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Publication number
CN1956739B
CN1956739B CN2005800170355A CN200580017035A CN1956739B CN 1956739 B CN1956739 B CN 1956739B CN 2005800170355 A CN2005800170355 A CN 2005800170355A CN 200580017035 A CN200580017035 A CN 200580017035A CN 1956739 B CN1956739 B CN 1956739B
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CN
China
Prior art keywords
sample
virus
formalin
inactivation
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2005800170355A
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English (en)
Chinese (zh)
Other versions
CN1956739A (zh
Inventor
M·里特
W·芒德特
N·巴里特
O·基斯特纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Co
Nanomedicine
Original Assignee
Baxter Healthcare SA
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of CN1956739A publication Critical patent/CN1956739A/zh
Application granted granted Critical
Publication of CN1956739B publication Critical patent/CN1956739B/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0047Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M31/00Means for providing, directing, scattering or concentrating light
    • C12M31/02Means for providing, directing, scattering or concentrating light located outside the reactor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10Apparatus features
    • A61L2202/11Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2005800170355A 2004-05-27 2005-05-26 灭活样品所含病毒的方法 Expired - Lifetime CN1956739B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57531004P 2004-05-27 2004-05-27
US60/575,310 2004-05-27
PCT/EP2005/005691 WO2005118000A1 (en) 2004-05-27 2005-05-26 Inactivation of a pathogen in a sample by a treatment with formalin and uv light

Publications (2)

Publication Number Publication Date
CN1956739A CN1956739A (zh) 2007-05-02
CN1956739B true CN1956739B (zh) 2011-12-28

Family

ID=34968615

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800170355A Expired - Lifetime CN1956739B (zh) 2004-05-27 2005-05-26 灭活样品所含病毒的方法

Country Status (17)

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EP (1) EP1753470B1 (enExample)
JP (2) JP5502276B2 (enExample)
KR (1) KR101483337B1 (enExample)
CN (1) CN1956739B (enExample)
AU (1) AU2005249204B2 (enExample)
BR (1) BRPI0511467A (enExample)
CA (1) CA2567336C (enExample)
CR (1) CR8805A (enExample)
EA (1) EA010428B1 (enExample)
EC (1) ECSP067118A (enExample)
ES (1) ES2553457T3 (enExample)
IL (1) IL179262A (enExample)
MX (1) MXPA06013633A (enExample)
NO (1) NO20065912L (enExample)
NZ (1) NZ551857A (enExample)
WO (1) WO2005118000A1 (enExample)
ZA (1) ZA200610490B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005249204B2 (en) * 2004-05-27 2010-07-15 Nanotherapeutics, Inc. Inactivation of a pathogen in a sample by a treatment with formalin and UV light
GB0706507D0 (en) * 2007-04-03 2007-05-09 Medi Immune Ltd Protective device
DE602008006410D1 (de) * 2007-06-15 2011-06-01 Amgen Inc Verfahren zur behandlung von zellkulturmedien für die verwendung in einem bioreaktor
ES2562818T3 (es) * 2010-05-03 2016-03-08 Glaxosmithkline Biologicals S.A. Procedimiento de inactivación del virus de la gripe
JP5968795B2 (ja) * 2013-01-10 2016-08-10 四国化工機株式会社 紫外線殺菌装置
CN103992936B (zh) * 2014-04-22 2015-10-07 北京科兴生物制品有限公司 一种封闭式甲醛灭活病毒管道系统及其应用
EP3829668A2 (en) 2018-07-27 2021-06-09 Terumo BCT Biotechnologies, LLC Fluid flow-through
CN111840596B (zh) * 2020-06-11 2022-03-11 南岳生物制药有限公司 核黄素光化学血浆灭活装置及其控制系统、控制方法
WO2022024589A1 (ja) 2020-07-27 2022-02-03 国立研究開発法人理化学研究所 感染防止装置及び感染防止方法
US12447225B2 (en) 2021-06-25 2025-10-21 University Of South Florida Ultrafast-UV laser integrating cavity mediated inactivation of a pathogen
CN114229953B (zh) * 2021-12-25 2022-11-18 无锡诚源环境科技有限公司 腔体式紫外消毒器的紫外线剂量计算方法
GB2631765A (en) * 2023-07-13 2025-01-15 Univ Cranfield Viral inactivation reactor and method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247178A (en) * 1991-12-12 1993-09-21 Fusion Systems Corporation Method and apparatus for treating fluids by focusing reflected light on a thin fluid layer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB802048A (en) * 1955-08-26 1958-09-24 Parke Davis & Co Vaccine products and method for producing the same
US3926556A (en) * 1973-05-30 1975-12-16 Raymond Marcel Gut Boucher Biocidal electromagnetic synergistic process
SU1367487A1 (ru) * 1986-01-29 1995-10-27 Институт полиомиелита и вирусных энцефалитов АМН СССР Способ получения антирабической вакцины
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
DE10056096A1 (de) * 2000-11-13 2002-06-13 Bayer Ag Vorrichtung zur Bestrahlung von Flüssigkeiten
AU2005249204B2 (en) * 2004-05-27 2010-07-15 Nanotherapeutics, Inc. Inactivation of a pathogen in a sample by a treatment with formalin and UV light

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247178A (en) * 1991-12-12 1993-09-21 Fusion Systems Corporation Method and apparatus for treating fluids by focusing reflected light on a thin fluid layer

Also Published As

Publication number Publication date
KR101483337B1 (ko) 2015-01-15
IL179262A0 (en) 2007-03-08
CR8805A (es) 2007-06-19
ES2553457T3 (es) 2015-12-09
WO2005118000A1 (en) 2005-12-15
MXPA06013633A (es) 2007-03-23
EA200602206A1 (ru) 2007-04-27
BRPI0511467A (pt) 2007-12-26
JP2008500303A (ja) 2008-01-10
HK1105374A1 (en) 2008-02-15
NZ551857A (en) 2009-11-27
IL179262A (en) 2011-01-31
JP5502276B2 (ja) 2014-05-28
AU2005249204B2 (en) 2010-07-15
EA010428B1 (ru) 2008-08-29
KR20110099810A (ko) 2011-09-08
AU2005249204A1 (en) 2005-12-15
EP1753470A1 (en) 2007-02-21
JP2012143249A (ja) 2012-08-02
CA2567336C (en) 2010-11-23
CA2567336A1 (en) 2005-12-15
JP5675690B2 (ja) 2015-02-25
ZA200610490B (en) 2008-10-29
ECSP067118A (enExample) 2007-02-28
CN1956739A (zh) 2007-05-02
NO20065912L (no) 2007-02-26
EP1753470B1 (en) 2015-08-19

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