CN1943754A - A Medicine for treatment of gastrointestinal diseases - Google Patents

Abstract

A medicine used in the treatment of gastrointestinal diseases, comprising the following ingredients by weight: rhizoma bletillae 10-30 doses, halloysitum rubrum10-30 doses, concha arcae 10-30 doses, wuzeigu 10-30 doses, fructus amomi 10-30 doses, radix codonopsis10-30 doses, rhizoma corydalis 10-30 doses, rhizoma atractylodis macrocephalae 10-30 doses. rhizoma coptidis 10-30 doses, massa fermentata10-30 doses, rhizoma atractylodis10-30 doses, radix astragali 10-30 doses. The invention has the advantages of effective, high cure rate, no relapse and so on.

Description

A kind of medicine for the treatment of gastrointestinal disease

Technical field

The present invention is a kind of medicine and method for making thereof for the treatment of gastrointestinal disease.

Background technology

At present, gastrointestinal disease is human commonly encountered diseases, frequently-occurring disease, is worldwide distribution, estimates to have approximately 10% population to suffer from this disease in life.Mainly comprise symptoms such as acute or chronic gastritis, functional dyspepsia, main performance has epigastrium flatulence discomfort, burning sensation or pain, anorexia or early full, feel sick, vomiting, dim gas, acid regurgitation and noisy sense and digestive tract hemorrhage etc.Therapeutic Principle, method are varied, at present, on the market medicine of treatment gastrointestinal disease have that WEIDE is peaceful, bismuth potassium citrate, gavirin tablet, gastrointestinal peace sheet etc., these medicines be mostly simple anti-inflammation or simple by gastric acid inhibitory, in and gastric acid control some symptoms of gastroenteropathy, in case drug withdrawal, relapse rate is high.

Summary of the invention

Therefore, still there is demand in people for the medicine of the treatment gastrointestinal disease of better efficacy.Up to now, also do not find the report of any relevant pharmaceutical composition of the present invention.The inventor according to a large amount of clinical practices, proves and adopts Drug therapy of the present invention that through research for many years the cure rate height does not recur after healing.

The medicine of the treatment gastrointestinal disease that the purpose of this invention is to provide a kind of cure rate height of better efficacy, do not recur after more.

The consumption of drug component of the present invention is repeatedly studied with the clinical trial summary through the inventor and is drawn, and each amounts of components is for all to have better curative effect in the following weight parts scope:

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Halloysitum Rubrum 10-30 part, Concha Arcae 10-30 part, Os Sepiae 10-30 part, Fructus Amomi 10-30 part, Radix Codonopsis 10-30 part, Rhizoma Corydalis 10-30 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Coptidis 10-30 part, Massa Medicata Fermentata 10-30 part, Rhizoma Atractylodis 10-30 part, Radix Astragali 10-30 part.

Be preferably: 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Halloysitum Rubrums, 15 parts of Concha Arcaes, 20 parts of Os Sepiae, 20 parts of Fructus Amomis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Corydalis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Coptidis, 15 parts of Massa Medicata Fermentata, 15 parts of Rhizoma Atractylodis, 15 parts of the Radixs Astragali.Said medicine all can directly have been bought in pharmacy.

Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.

The pharmacological action of each constituent medicine of the present invention is as follows:

The Pseudobulbus Bletillae (Rhizoma Bletillae): tonifying the lung hemostasis, nourishing the stomach granulation promoting.Be applicable to that lung gastrorrhagia, gastric and duodenal ulcers are hemorrhage etc.

Halloysitum Rubrum: Halloysitum Rubrum is a Kaolin, red smooth matter exquisiteness, the sticking tongue earth gas of licking, astringing intestine to stop diarrhea hemostasis and granulation promoting.

Concha Arcae: expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.Be used for the long-pending knot of pertinacious phlegm, the thickness difficulty is coughed up, goiter, scrofula, abdominal mass mass in the abdomen, stomachache pantothenic acid.

Os Sepiae: Os Sepiae has nourishing the stomach benefit essence, astringing to arrest bleeding, relieving gastric hyperacidity to alleviate stomachache, expelling pus and promoting granulation effect.

Fructus Amomi: promoting the circulation of QI to relieve pain, spleen invigorating relieving distension, antiabortive preventing or arresting vomiting.Through test fragrant digestion promoting function is arranged, can promote the secretion of peptic digestion liquid, and get rid of the digestive tract pneumatosis.Clinical stagnation of QI in spleen and stomach, the stomachache distension of being used for; Deficiency and coldness of spleen and stomach, feeling of stuffiness in chest vomiting.

Radix Codonopsis: can invigorating the spleen and replenishing QI, to control deficiently, the lack of appetite body is tired, and chronic diarrhea is quenched one's thirst.

Rhizoma Corydalis: effect with blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain.

The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, warm in nature, go into the taste warp, good air making-up and spleen enlivening effect is arranged.

Rhizoma Coptidis: the effect of eliminating fire and detoxication.

Massa Medicata Fermentata: can strengthen the effect of its promoting digestion and removing stagnation, invigorating the spleen and regulating the stomach behind the parching to brown.

Rhizoma Atractylodis: have spleen invigorating, dampness, resolving depression, ward off dirty, the effect of expelling cold and relieving exterior syndrome.

The Radix Astragali: have invigorating QI to consolidate the body surface resistance, the effect of holder skin ulcer granulation promoting, diuretic.

Cure mainly: gastric ulcer, duodenal ulcer, upper gastrointestinal hemorrhage, various gastritis.

Function: the cold expelling that is good for the stomach, putrefaction removing and tissue regeneration promoting.

Advantages such as that the present invention has is evident in efficacy, cure rate is high, do not recur after more.

The specific embodiment

[clinical efficacy test report]

1, physical data

Accept out-patient's totally 100 examples for medical treatment, wherein male 70 examples, women 30 examples, age 15-30 year 38 examples, 31-40 year 22 examples, 41-50 year 23 examples, 17 examples more than 50 years old.

2, Therapeutic Method

Medicine of the present invention is summed up through clinical trial for many years, and for symptoms such as gastric ulcer, duodenal ulcer, upper gastrointestinal hemorrhage, various gastritis, 15 days is a course of treatment, usage and dosage is: oral, three times on the one, each 10 grams are taken a course of treatment or two courses of treatment.

3, efficacy assessment standard

Produce effects: all clinical symptom disappearance, drug withdrawal are followed up a case by regular visits to and are not seen recurrence more than half a year;

Take a turn for the better: all clinical symptom disappearance, drug withdrawal are followed up a case by regular visits to a light symptoms half a year by chance;

Invalid: it is invalid not meeting effective standard.

4, therapeutic outcome (see Table 1)

Table 1 is observation of curative effect after treating

Week treatment time	Produce effects		Take a turn for the better		Invalid		Effective percentage %
								The example number	Obvious effective rate %	The example number	Improvement rate %	The example number	Inefficiency %
	1234 (one months)	30 70 90 99	30 70 90 99	70 30 10 1	70 30 10 1	0 0 0								0 0 0	100 100 100 100

In a word, in two months clinical practice, with medicine of the present invention treatment patient 100 examples, produce effects 99 examples as a result, 1 example that takes a turn for the better, invalid 0 example, obvious effective rate is 99%, and improvement rate is 1%, and total effective rate is 99%.

Come further to illustrate medicine of the present invention and preparation method thereof by the following examples.

Embodiment 1

The consumption of drug component of the present invention is repeatedly studied with the clinical trial summary through the inventor and is drawn, and each amounts of components is preferably: 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Halloysitum Rubrums, 15 parts of Concha Arcaes, 20 parts of Os Sepiae, 20 parts of Fructus Amomis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Corydalis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Coptidis, 15 parts of Massa Medicata Fermentata, 15 parts of Rhizoma Atractylodis, 15 parts of the Radixs Astragali.

Said medicine all can directly have been bought in pharmacy.

Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.

Embodiment 2

10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Halloysitum Rubrums, 10 parts of Concha Arcaes, 10 parts of Os Sepiae, 10 parts of Fructus Amomis, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Corydalis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Coptidis, 30 parts of Massa Medicata Fermentata, 30 parts of Rhizoma Atractylodis, 30 parts of the Radixs Astragali.

Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.

Embodiment 3

30 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Halloysitum Rubrums, 30 parts of Concha Arcaes, 30 parts of Os Sepiae, 30 parts of Fructus Amomis, 10 parts of Radix Codonopsis, 10 parts of Rhizoma Corydalis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Rhizoma Coptidis, 10 parts of Massa Medicata Fermentata, 10 parts of Rhizoma Atractylodis, 10 parts of the Radixs Astragali.

Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.

Claims (1)

1, a kind of medicine for the treatment of gastrointestinal disease is characterized in that this medicine is to be made by weight ratio by following compositions:

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Halloysitum Rubrum 10-30 part, Concha Arcae 10-30 part, Os Sepiae 10-30 part, Fructus Amomi 10-30 part, Radix Codonopsis 10-30 part, Rhizoma Corydalis 10-30 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Coptidis 10-30 part, Massa Medicata Fermentata 10-30 part, Rhizoma Atractylodis 10-30 part, Radix Astragali 10-30 part.