CN101062221A - Medicine for treating gastric ulcer and duodenal ulcer - Google Patents

Abstract

The invention relates to a medicament for treating gastric ulcer and duodenal ulcer, which is prepared from the following medicinal herbs (by weight ratio) as raw material: dragon's blood resin 18-30 parts, rhizoma corydalis 5-10 parts, atractylodes rhizome 5-10 parts, licorice root 5-10 parts, blood clam shell 10-20 parts, cyprus longus 5-30 parts, dried orange peel 5-18 parts, cuttle-bone 10-50 parts.

Description

A kind of medicine for the treatment of stomach, duodenal ulcer

Technical field

The present invention relates to the medicine of a kind of pure treatment by Chinese herbs stomach, duodenal ulcer, its trade name is loose for the peace stomach.

Background technology

At present, gastrointestinal disease is human commonly encountered diseases, frequently-occurring disease, is worldwide distribution, estimates to have approximately 10% population to suffer from this disease in life.Mainly comprise symptoms such as acute or chronic gastritis, functional dyspepsia, main performance has epigastrium flatulence discomfort, burning sensation or pain, anorexia or early full, feel sick, vomiting, belch, acid regurgitation and noisy sense and digestive tract hemorrhage etc.Therapeutic Principle, method are varied, at present, on the market medicine of treatment gastrointestinal disease have that WEIDE is peaceful, bismuth potassium citrate, gavirin tablet, gastrointestinal peace sheet etc., these medicines be mostly simple anti-inflammation or simple by gastric acid inhibitory, in and gastric acid control some symptoms of gastroenteropathy, in case drug withdrawal, relapse rate is high.

Summary of the invention

Therefore, still there is demand in people for the medicine of the treatment gastrointestinal disease of better efficacy.Up to now, also do not find the report of any relevant pharmaceutical composition of the present invention.The inventor, proves and adopts Drug therapy of the present invention according to a large amount of clinical practices through research for many years, the cure rate height, and relapse rate is low.

The purpose of this invention is to provide the low treatment stomach of a kind of cure rate height, relapse rate of better efficacy, the medicine of duodenal ulcer.

The consumption of drug component of the present invention is repeatedly studied with the clinical trial summary through the inventor and is drawn, and each amounts of components is for all to have better curative effect in the following weight parts scope:

A kind of medicine for the treatment of stomach, ulcer and duodenal ulcer is characterized in that it is to be made by following bulk drugs: Rhizoma Polygoni Paleachi 18-30 part, Rhizoma Corydalis 5-10 part, Rhizoma Atractylodis 5-10 part, Radix Glycyrrhizae 5-10 part, Concha Arcae 10-20 part, Rhizoma Cyperi 5-30 part, Pericarpium Citri Reticulatae 5-18 part, Os Sepiae 10-50 part.

The described medicine wherein best proportioning of crude drug is: 30 parts of Rhizoma Polygoni Paleachi, 10 parts of Rhizoma Corydalis, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Glycyrrhizae, 20 parts of Concha Arcaes, 5 parts of Rhizoma Cyperi, 5 parts of Pericarpium Citri Reticulataes, 10 parts of Os Sepiae.

In above-mentioned raw materials, the effect of Rhizoma Polygoni Paleachi is the blood hemostasis of loosing, therapeutic method to keep the adverse QI flowing downwards pain relieving.Be used to control chronic gastritis, stomach, duodenal ulcer, food stagnation ， lumps in the chest and abdomen.Rhizoma Corydalis has promoting blood circulation to remove blood stasis, promoting the circulation of QI analgesic function.Rhizoma Atractylodis have spleen invigorating, dampness, and resolving depression is warded off dirty function, controls wet the Sheng and is stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting.Radix Glycyrrhizae has the weakness of the spleen and stomach of controlling, lack of appetite, the effect of stomachache loose stool.Concha Arcae is controlled accumulation of phlegm, and stomachache is noisy, acid regurgitation.Rhizoma Cyperi is a perennial herb, and underground tool spins Duo shape tuber.Stem is upright, prismatic, and basic leafing is linear, small ear lenticular wire shape, bronzing, fringe is lined up umbrella shape.Tuber is used as medicine, claims " Rhizoma Cyperi ", and acrid in the mouth, little hardship, property is flat, the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.Treat for stomachache dyspepsia.Pericarpium Citri Reticulatae has the effect of strengthening the spleen stomach.Os Sepiae has astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, and relieving gastric hyperacidity to alleviate stomachache, removing dampness is held back skin ulcer.Cure mainly haematemesis, hematemesis, metrorrhagia is had blood in stool, epistaxis, wound hemorrhage; It is noisy to have a stomachache, belch pantothenic acid; Eczema ulcer.

The preparation method of described medicine is characterized in that this method comprises the following steps:

1) weighting raw materials Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Rhizoma Corydalis, Radix Glycyrrhizae, Rhizoma Cyperi, Rhizoma Polygoni Paleachi, Os Sepiae, Concha Arcae are standby;

2) get the raw material Os Sepiae and insert the interior little yellow of slow fire parch of using of marmite, it is standby to take the dish out of the pot;

3) get Concha Arcae and put in the carbon stove calcine sustainability, standby;

4) Rhizoma Polygoni Paleachi of described weight proportion, liquorice beverage are decocted 3 times, each amount of water exceeds powder and is as the criterion, and merges 3 times decocting liquid, filtration, and it is standby to be condensed into cream;

5) with Rhizoma Atractylodis, Rhizoma Cyperi, Pericarpium Citri Reticulatae, Rhizoma Corydalis, the Concha Arcae (calcined) of above-mentioned weight proportion, that the stir-fry Os Sepiae is beaten the powder mixing with machine is standby;

6) condensed cream is mixed with medicated powder, beats powder once more through super-dry and incapsulate, medicine of the present invention.

Medicine of the present invention can also adopt conventional pharmaceutical methods to make medicines such as powder, tablet, watered pill dosage form for oral administration.

Formulation method: be ground into fine powder (80 mesh sieves-100 mesh sieve) dress 0# capsule, every capsules 0.5g

Cure mainly: gastric abscess (peptic gastric ulcer) primary symptom: the scorching hot pain of gastral cavilty portion is shown effect repeatedly, stomachache acid regurgitation, flatulence

Instructions about how to take medicine: oral, each 3, every day 2 times, 30 minutes ante cibum, warm water takes, 15 days one courses of treatment

Taboo: anemia of pregnant woman forbidding, give up alcohol, the river snakeheaded fish

Compared with prior art, medicine provided by the invention has the following advantages and remarkable result: the present invention shows effect repeatedly to gastric abscess (peptic gastric ulcer), the scorching hot pain of gastral cavilty portion, the stomachache acid regurgitation, and the treatment of diseases such as flatulence has positive effect, can reach the damp eliminating detumescence, the therapeutic efficiency of blood stasis dispersing and fresh blood promoting.Cure rate 95%, total effective rate 100%.

The specific embodiment

[clinical observation]

1, physical data

Accept out-patient's totally 482 examples for medical treatment, wherein male 307 examples, women 175 examples, men and women's ratio is 1.75: 1.Age 15-30 year 23 examples, 31-65 year 459 examples.

2, diagnostic criteria: tcm syndrome differentiation and typing, doctor trained in Western medicine check diagnosis.

3, Therapeutic Method

Oral, every day 2 times, each 3,30 minutes ante cibum, warm water takes, 15 days one courses of treatment

4, efficacy assessment standard

Cure: transference cure, drug withdrawal is not recurred March.

Produce effects: transference cure.

Effectively: sx.

Invalid: symptom does not have change.

3, therapeutic outcome statistics

Week treatment time	Invalid		Effectively		Produce effects		Cure		Total effective rate
										The example number	Inefficiency	The example number	Effective percentage	The example number	Obvious effective rate	The example number	Cure rate
	4 all 5 weeks of 3 weeks in 2 weeks in 1 week	217 121 72 24 0	45％ 25％ 15％ 5％ 0％	227 145 97 24 9	47 30％ 20％ 5％ 2％	39 192 217 48 14	8 40％ 45％ 10％ 3％	0 24 96 386 459										0 5％ 20％ 80％ 95％	55％ 75％ 85％ 95％ 100％

In a word, in the treatment in 4 weeks, with Drug therapy patient's 482 examples of the present invention, the result cures 459 examples, produce effects 14 examples, effective 9 examples, invalid 0 example, cure rate 95%, obvious effective rate 3%, total effective rate 100%.

Come further to set forth the preparation method of medicine of the present invention by the following examples.

Embodiment 1:

A kind of medicine for the treatment of stomach, ulcer and duodenal ulcer, it is to be made by following bulk drugs:: 30 parts of Rhizoma Polygoni Paleachi, 10 parts of Rhizoma Corydalis, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Glycyrrhizae, 20 parts of Concha Arcaes, 5 parts of Rhizoma Cyperi, 5 parts of Pericarpium Citri Reticulataes, 10 parts of Os Sepiae.

The preparation method of described medicine is characterized in that this method comprises the following steps:

1) weighting raw materials Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Rhizoma Corydalis, Radix Glycyrrhizae, Rhizoma Cyperi, Rhizoma Polygoni Paleachi, Os Sepiae, Concha Arcae are standby;

2) get the raw material Os Sepiae and insert the interior little yellow of slow fire parch of using of marmite, it is standby to take the dish out of the pot;

3) get Concha Arcae and put in the carbon stove calcine sustainability, standby;

4) Rhizoma Polygoni Paleachi of described weight proportion, liquorice beverage are decocted 3 times, each amount of water exceeds powder and is as the criterion, and merges 3 times decocting liquid, filtration, and it is standby to be condensed into cream;

5) with Rhizoma Atractylodis, Rhizoma Cyperi, Pericarpium Citri Reticulatae, Rhizoma Corydalis, the Concha Arcae (calcined) of above-mentioned weight proportion, that the stir-fry Os Sepiae is beaten the powder mixing with machine is standby;

6) condensed cream is mixed with medicated powder, beats powder once more through super-dry and incapsulate, medicine of the present invention.

Embodiment 2:

A kind of medicine for the treatment of stomach, ulcer and duodenal ulcer, it is to be made by following bulk drugs: 18 parts of Rhizoma Polygoni Paleachi, 5 parts of Rhizoma Corydalis, 5 parts of Rhizoma Atractylodis, 10 parts in Radix Glycyrrhizae, 20 parts of Concha Arcaes, 30 parts of Rhizoma Cyperi, 5 parts of Pericarpium Citri Reticulataes, 50 parts of Os Sepiae.Method for making is with embodiment 1.

Embodiment 3:

A kind of medicine for the treatment of stomach, ulcer and duodenal ulcer, it is to be made by following bulk drugs: 30 parts of Rhizoma Polygoni Paleachi, 10 parts of Rhizoma Corydalis, 10 parts of Rhizoma Atractylodis, 5 parts in Radix Glycyrrhizae, 10 parts of Concha Arcaes, 5 parts of Rhizoma Cyperi, 18 parts of Pericarpium Citri Reticulataes, 10 parts of Os Sepiae.Method for making is with embodiment 1.

Claims (3)

1, a kind of medicine for the treatment of stomach, ulcer and duodenal ulcer is characterized in that it is to be made by following bulk drugs: Rhizoma Polygoni Paleachi 18-30 part, Rhizoma Corydalis 5-10 part, Rhizoma Atractylodis 5-10 part, Radix Glycyrrhizae 5-10 part, Concha Arcae 10-20 part, Rhizoma Cyperi 5-30 part, Pericarpium Citri Reticulatae 5-18 part, Os Sepiae 10-50 part.

2, the medicine of treatment stomach according to claim 1, ulcer and duodenal ulcer, it is characterized in that described medicine wherein the best proportioning of crude drug be: 30 parts of Rhizoma Polygoni Paleachi, 10 parts of Rhizoma Corydalis, 10 parts of Rhizoma Atractylodis, 10 parts in Radix Glycyrrhizae, 20 parts of Concha Arcaes, 5 parts of Rhizoma Cyperi, 5 parts of Pericarpium Citri Reticulataes, 10 parts of Os Sepiae.

3,, it is characterized in that this method comprises the following steps: according to the preparation method of claim 1 or 2 described medicines

1) weighting raw materials Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Rhizoma Corydalis, Radix Glycyrrhizae, Rhizoma Cyperi, Rhizoma Polygoni Paleachi, Os Sepiae, Concha Arcae are standby;

2) get the raw material Os Sepiae and insert the interior little yellow of slow fire parch of using of marmite, it is standby to take the dish out of the pot;

3) get Concha Arcae and insert in the carbon stove calcine sustainability, standby;

4) Rhizoma Polygoni Paleachi of described weight proportion, liquorice beverage are decocted 3 times, each amount of water exceeds powder and is as the criterion, and merges 3 times decocting liquid, filtration, and it is standby to be condensed into cream;

5) with Rhizoma Atractylodis, Rhizoma Cyperi, Pericarpium Citri Reticulatae, Rhizoma Corydalis, the Concha Arcae (calcined) of above-mentioned weight proportion, that the stir-fry Os Sepiae is beaten the powder mixing with machine is standby;

6) condensed cream is mixed with medicated powder, beats powder once more through super-dry and incapsulate, medicine of the present invention.