CN101406611B - Chinese medicine preparation for treating bronchial asthma - Google Patents
Chinese medicine preparation for treating bronchial asthma Download PDFInfo
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- CN101406611B CN101406611B CN2008102308473A CN200810230847A CN101406611B CN 101406611 B CN101406611 B CN 101406611B CN 2008102308473 A CN2008102308473 A CN 2008102308473A CN 200810230847 A CN200810230847 A CN 200810230847A CN 101406611 B CN101406611 B CN 101406611B
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating bronchial asthma, which is mainly prepared from the following traditional Chinese medicines in weight portion: 5 to 10 portions of honey-baked Chinese ephedra, 5 to 10 portions of cinnamon twig, 10 to 20 portions of bitter almond, 10 to 20 portions of Unibract Fritillary Bulb, 10 to 15 portions of liquorice, 15 to 30 portions of Japanese ardisia, 10 to 20 portions of radix salviae miltiorrhizae, 5 to 15 portions of ordate houttuynia, 10 to 20 portions of dried orange peel, 5 to 10 portions of batryticated silkworm, 5 to 10 portions of earthworm, and 10 to 15 portions of tokay. The preparation combines the honey-baked Chinese ephedra, the cinnamon twig, the bitter almond, the Unibract Fritillary Bulb, the liquorice, the Japanese ardisia, the radix salviae miltiorrhizae, the ordate houttuynia, the dried orange peel, the batryticated silkworm, the earthworm and the tokay, and the combination of the medicines makes the efficacies of all medicines generate synergic action, thereby effectively treating the bronchial asthma. As the preparation adopts the combination of the medicines, and the combination of the medicines makes the efficacies of the medicines generate synergic action, thereby more effectively treating the bronchial asthma. Compared with the prior art, the preparation has the advantages thatthe preparation has no toxic and side effects, can treat both principal and secondary aspect of the disease, and can more effectively treat the bronchial asthma.
Description
Affiliated technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of bronchial asthma.
Background technology
Contact sucks pollen, dirt demodicid mite, fungus etc. or because of infecting, medicine etc. cause bronchial mucosa swelling, hyperemia, and inflammatory cell infiltration airway smooth muscle spasm in the secretions increase, air flue forms bronchial asthma; The main reveal any symptoms of bronchial asthma is: pant, expiratory dyspnea, uncomfortable in chest or yawn cough night and the early morning outbreak etc. of being everlasting.The medicine of clinical treatment bronchial asthma, many and random, there are many drawbacks, as albuterol (salbutamol), mainly be loose bronchial smooth muscle, the inflammation-inhibiting medium discharges, and removes bronchospasm and promotes mucous secretion and ciliary movement, strengthen air flue and remove function, but side effect is bigger, and heavy dose can cause cardiopalmus, headache, dizziness, feel sick, and prolonged and repeated medication can cause that airway reactivity increases, asthma attack increases the weight of, and mortality rate increases.Aminophylline, main effect is loose bronchial smooth muscle, antiinflammatory, side effect is: the oral offices such as nauseating, vomiting, stomachache that cause stimulate central excitation symptoms such as dysphoria, insomnia, excessive headache, the dizzy delirium convulsions of causing of dosage.
Summary of the invention
Therefore, still there is demand in the Chinese medicine preparation that people better treat bronchial asthma to curative effect, up to now also do not find the report of any relevant pharmaceutical composition of the present invention, the inventor is through research repeatedly, finally find the Chinese medicine preparation of the treatment bronchial asthma of better efficacy, thereby finished the present invention.
The purpose of this invention is to provide and a kind ofly have no side effect, treating both the principal and secondary aspects of a disease, can more effectively treat the Chinese medicine preparation of bronchial asthma.
The consumption of drug component of the present invention is that the inventor gets through groping in a large number to sum up, and each amounts of components all has curative effect preferably in following weight parts: 5-10 parts of Herba Ephedrae (processed), 5-10 parts of Ramulus Cinnamomi, 10-20 parts of Semen Armeniacae Amarums, 10-20 parts of Bulbus Fritillariae Cirrhosaes, 10-15 parts in Radix Glycyrrhizae, 15-30 parts of Herba Ardisiae Japonicaes, 10-20 parts of Radix Salviae Miltiorrhizaes, 5-15 parts of Herba Houttuyniae, 10-20 parts of Pericarpium Citri Reticulataes, 5-10 parts of Bombyx Batryticatus, 5-10 parts of Pheretimas, 10-15 parts of Geckos.
Medicament selection Herba Ephedrae (processed) of the present invention, Ramulus Cinnamomi, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Herba Ardisiae Japonicae, Radix Salviae Miltiorrhizae, Herba Houttuyniae, Pericarpium Citri Reticulatae, Bombyx Batryticatus, Pheretima and Gecko make up, make each efficacy of drugs produce synergism, thereby effectively treat bronchial asthma, wherein selecting Herba Ephedrae (processed), Ramulus Cinnamomi, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Herba Ardisiae Japonicae, Radix Salviae Miltiorrhizae, Herba Houttuyniae, Pericarpium Citri Reticulatae, Bombyx Batryticatus, Pheretima, Gecko for use, is because of Herba Ephedrae (processed), Herba Ephedrae (processed) meridian distribution of property and flavor suffering, little hardship, temperature; Return lung, urinary bladder channel; Function cures mainly: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, utilize detumescence; Be used for anemofrigid cold, cough and asthma, edema due to wind pathogen edema.Ramulus Cinnamomi, Ramulus Cinnamomi meridian distribution of property and flavor suffering, sweet, warm; GUIXIN, lung, urinary bladder channel; Function cures mainly: the diaphoresis expelling pathogenic factors from muscles, and promoting the flow of QI-blood by warming the meridian, supporing yang activating QI is used for the cold flu of gas, all pain cards of cold coagulation stasis, phlegm retention, syndrome of water-retention, cardiopalmus.Semen Armeniacae Amarum, Semen Armeniacae Amarum meridian distribution of property and flavor hardship, tepor, slightly poisonous lung, the large intestine channel of returning; Function cures mainly: relieving cough and asthma, loosening bowel to relieve constipation; Be used for cough and asthma, the dryness of the intestine constipation.Bulbus Fritillariae Cirrhosae, Bulbus Fritillariae Cirrhosae meridian distribution of property and flavor, hardship, sweet, be slightly cold, return lung, heart channel; Function cures mainly: removing heat-phlegm, nourishing the lung to arrest cough, mass dissipating and swelling eliminating; Be used for cough due to consumptive disease, lung-heat type cough, sick and weary, acute mastitis, lung abscess.Radix Glycyrrhizae, Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Function cures mainly: invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription; Be used for: deficiency of heart-QI, swim and tie generation, severe palpitation, syndrome of deficiency of spleen qi, cough with asthma, pathopyretic ulcer, laryngopharynx swelling and pain, the medicine food is poisoned, the mediation property of medicine.Herba Ardisiae Japonicae: meridian distribution of property and flavor: bitter, hot, flat; Return lung, Liver Channel; Function master lifts: relieving cough and asthma, eliminating damp-heat, invigorating blood circulation addiction; Be used for cough with asthma, damp and hot yellow cellulitis, edema, blood addiction amenorrhea, rheumatic arthralgia, traumatic injury.Radix Salviae Miltiorrhizae: meridian distribution of property and flavor: hardship is slightly cold; GUIXIN, pericardium, Liver Channel; Function cures mainly: promoting blood flow to regulate menstruation, and the addiction of dispelling pain relieving, removing heat from blood disappears bitterly, and relieving restlessness is calmed the nerves.Herba Houttuyniae: meridian distribution of property and flavor: suffering is slightly cold; Return lung meridian. Function cures mainly: heat-clearing and toxic substances removing, the pain that disappears evacuation of pus, inducing diuresis for treating stranguria syndrome.Pericarpium Citri Reticulatae: meridian distribution of property and flavor: hot, bitter, warm; Return spleen, lung meridian; Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Bombyx Batryticatus: meridian distribution of property and flavor: salty, hot, flat; Return liver, lung, stomach warp; Function cures mainly:. expelling wind for relieving convulsion, dissipating phlegm and resolving masses.Pheretima meridian distribution of property and flavor: salty, cold; Return liver, spleen, urinary bladder channel; Function cures mainly: the heat clearing away arresting convulsion, collateral dredging is relievingd asthma, diuresis. Be used for: the frightened pain of hyperpyrexia, demented, blood stagnancy due to deficiency of QI, hemiplegia, lung-heat asthma, dysuria, urine retention is obstructed.Gecko, meridian distribution of property and flavor: salty, flat; Return lung, kidney channel; Function cures mainly: invigorating the lung and the kidney, and helping inspiration to relieve asthma, supporing yang benefit is smart; Be used for: the cough due to deficiency of the lung, to suffer from a deficiency of the kidney and do to breathe heavily, asthenia is breathed with cough, the positive paralysis of suffering from a deficiency of the kidney.Because the present invention adopts said medicine to make up, make each efficacy of drugs produce synergism these drug regimens, can more effectively treat bronchial asthma; Compared with prior art, the present invention have have no side effect, treating both the principal and secondary aspects of a disease, can more effectively treat the advantage of bronchial asthma.
The specific embodiment
The present invention is made by following bulk drugs: 5-10 parts of Herba Ephedrae (processed), 5-10 parts of Ramulus Cinnamomi, 10-20 parts of Semen Armeniacae Amarums, 10-20 parts of Bulbus Fritillariae Cirrhosaes, 10-15 parts in Radix Glycyrrhizae, 15-30 parts of Herba Ardisiae Japonicaes, 10-20 parts of Radix Salviae Miltiorrhizaes, 5-15 parts of Herba Houttuyniae, 10-20 parts of Pericarpium Citri Reticulataes, 5-10 parts of Bombyx Batryticatus, 5-10 parts of Pheretimas, 10-15 parts of Geckos.
The present invention is made by following bulk drugs: 6-8 parts of Herba Ephedrae (processed), 6-8 parts of Ramulus Cinnamomi, 11-18 parts of Semen Armeniacae Amarums, 11-18 parts of Bulbus Fritillariae Cirrhosaes, 11-13 parts in Radix Glycyrrhizae, 16-28 parts of Herba Ardisiae Japonicaes, 11-18 parts of Radix Salviae Miltiorrhizaes, 6-13 parts of Herba Houttuyniae, 11-18 parts of Pericarpium Citri Reticulataes, 6-8 parts of Bombyx Batryticatus, 6-8 parts of Pheretimas, 11-13 parts of Geckos.
Embodiment 1:
The present invention is made by following bulk drugs: 5 parts of Herba Ephedrae (processed), 5 parts of Ramulus Cinnamomi, 10 parts of Semen Armeniacae Amarums, 10 parts of Bulbus Fritillariae Cirrhosaes, 10 parts in Radix Glycyrrhizae, 15 parts of Herba Ardisiae Japonicaes, 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Herba Houttuyniae, 10 parts of Pericarpium Citri Reticulataes, 5 parts of Bombyx Batryticatus, 5 parts of Pheretimas, 10 parts of Geckos.
5 parts of Herba Ephedrae (processed), 5 parts of Ramulus Cinnamomi, 10 parts of Semen Armeniacae Amarums, 10 parts of Bulbus Fritillariae Cirrhosaes, 10 parts in Radix Glycyrrhizae, 15 parts of Herba Ardisiae Japonicaes, 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of Herba Houttuyniae, 10 parts of Pericarpium Citri Reticulataes, 5 parts of Bombyx Batryticatus, 5 parts of Pheretimas, 10 parts of Geckos.
Embodiment 2:
The present invention is made by following bulk drugs: 6 parts of Herba Ephedrae (processed), 6 parts of Ramulus Cinnamomi, 11 parts of Semen Armeniacae Amarums, 11 parts of Bulbus Fritillariae Cirrhosaes, 11 parts in Radix Glycyrrhizae, 16 parts of Herba Ardisiae Japonicaes, 11 parts of Radix Salviae Miltiorrhizaes, 6 parts of Herba Houttuyniae, 11 parts of Pericarpium Citri Reticulataes, 6 parts of Bombyx Batryticatus, 6 parts of Pheretimas, 11 parts of Geckos.
Embodiment 3:
The present invention is made by following bulk drugs: 8 parts of Herba Ephedrae (processed), 8 parts of Ramulus Cinnamomi, 18 parts of Semen Armeniacae Amarums, 18 parts of Bulbus Fritillariae Cirrhosaes, 13 parts in Radix Glycyrrhizae, 28 parts of Herba Ardisiae Japonicaes, 18 parts of Radix Salviae Miltiorrhizaes, 13 parts of Herba Houttuyniae, 18 parts of Pericarpium Citri Reticulataes, 8 parts of Bombyx Batryticatus, 8 parts of Pheretimas, 13 parts of Geckos.
Embodiment 4:
The present invention is made by following bulk drugs: 10 parts of Herba Ephedrae (processed), 10 parts of Ramulus Cinnamomi, 20 parts of Semen Armeniacae Amarums, 20 parts of Bulbus Fritillariae Cirrhosaes, 15 parts in Radix Glycyrrhizae, 30 parts of Herba Ardisiae Japonicaes, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Herba Houttuyniae, 20 parts of Pericarpium Citri Reticulataes, 10 parts of Bombyx Batryticatus, 10 parts of Pheretimas, 15 parts of Geckos.
The present invention takes by weighing according to the said medicine weight proportion, mixes, and pulverizes, and sieves, and can make electuary, granule or capsule according to conventional method.
One, medicine major function of the present invention and therapeutic domain
1, major function: treatment is panted, expiratory dyspnea, uncomfortable in chest, cough etc.
2, therapeutic domain: pant, expiratory dyspnea uncomfortable in chest, cough etc.
3, usage and consumption: oral every day 3 times, each 4 grams, every capsules 1 gram, 40 minutes ante cibum or warm boiled water after meal, 15 days is a course of treatment, minimum taking 3 courses of treatment, the longest taking 6 courses of treatment.
Two, the clinical observation of medicine of the present invention
1, physical data
Accept out-patient's 320 examples for medical treatment, the patient is divided into two groups at random, lift treatment and organize 240 examples, give Drug therapy of the present invention, matched group 80 examples.Have Drug therapy; Minimum 12 years old of age wherein, maximum 70 years old, the longest 20 years the course of disease the shortest half a year, clinical treatment observation, the shortest 2 months, the longest 5 years.40 examples below 40 years old in the treatment group, 40-49 years old 50 example, 50-59 years old 94 example, 56 examples more than 60 years old; Course of disease person below 1 year 57 examples, 2-5 years 90 examples, 6-10 years 55 examples, person's 20 examples more than 10 years.16 examples of person below 40 years old in the matched group, 40-49 years old 42 example, 50-59 years old 14 example, person's 8 examples more than 60 years old.Course of disease person below 1 year 20 examples, 2-5 years 35 examples, 6-10 years 20 examples, person's 5 examples more than 10 years, two groups of patients are aspect mean age, the course of disease, the state of an illness, and are in a basic balance, have comparability.
2, diagnostic criteria
All case is that diagnosis is determined in diagnostic criteria by the bronchial asthma disease clinical manifestation all.
Pant, expiratory dyspnea, uncomfortable in chest, cough etc.
3, Therapeutic Method
Therapeutic Method is under the voluntary prerequisite of patient, patient is divided into two groups at random, and 240 examples are organized in treatment, take medicine of the present invention, each 4 grams, and every day 3 times, warm boiled water after meal, 15 days is a course of treatment, minimum taking 2 courses of treatment, the longest taking 6 courses of treatment.Matched group is totally 80 examples, takes the medicine that oneself has, each 4 grams, and every day 2, once 15 days was a course of treatment, minimum taking 2 courses of treatment, the longest taking 8 courses of treatment.
4, efficacy assessment standard (being as the criterion) with clinical symptom disappearance
Cure: no longer pant, breathes unobstructedly, disappearance uncomfortable in chest is no longer coughed; The asthmoid respiration difficulty, transference cure such as uncomfortable in chest, cough is as the criterion.
Produce effects: panting alleviates, respiratory passage unblocked, and uncomfortable in chest alleviating coughs sometimes, do not cough sometimes.
Effectively: panting alleviates, breathe unobstructed sometimes, obstructed sometimes, the cough cough sometimes, do not cough sometimes.
Invalid: as to pant, expiratory dyspnea uncomfortable in chest, cough etc.; Various symptoms do not have change substantially.
5, result and analysis (seeing Table 1)
Table 1 liang group curative effect relatively
| Group | The example number | Cure | Produce effects | Effectively | Invalid | Cure rate (%) | Total effective rate (%) |
| The treatment group | 240 | 102 | 83 | 50 | 5 | 42.5 | 97.9 |
| Matched group | 80 | 9 | 21 | 29 | 21 | 11.3 | 72.8 |
Therapeutic effect obviously is better than matched group as can be seen from Table 1, and its total effective rate, cure rate (97.9,42.5%) are all apparently higher than matched group (72.8,11.3).
Claims (1)
1. a Chinese medicine preparation for the treatment of bronchial asthma is characterized in that this Chinese medicine preparation is by descending bulk drugs to make: 5-10 parts of Herba Ephedrae (processed), 5-10 parts of Ramulus Cinnamomi, 10-20 parts of Semen Armeniacae Amarums, 10-20 parts of Bulbus Fritillariae Cirrhosaes, 10-15 parts in Radix Glycyrrhizae, 15-30 parts of Herba Ardisiae Japonicaes, 10-20 parts of Radix Salviae Miltiorrhizaes, 5-15 parts of Herba Houttuyniae, 10-20 parts of Pericarpium Citri Reticulataes, 5-10 parts of Bombyx Batryticatus, 5-10 parts of Pheretimas, 10-15 parts of Geckos.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102308473A CN101406611B (en) | 2008-11-12 | 2008-11-12 | Chinese medicine preparation for treating bronchial asthma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102308473A CN101406611B (en) | 2008-11-12 | 2008-11-12 | Chinese medicine preparation for treating bronchial asthma |
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| Publication Number | Publication Date |
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| CN101406611A CN101406611A (en) | 2009-04-15 |
| CN101406611B true CN101406611B (en) | 2011-10-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008102308473A Expired - Fee Related CN101406611B (en) | 2008-11-12 | 2008-11-12 | Chinese medicine preparation for treating bronchial asthma |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670867B (en) * | 2012-05-21 | 2013-10-09 | 张陆莲 | Traditional Chinese medicine preparation for treating bronchial asthma and preparation process for traditional Chinese medicine preparation |
| CN104189427B (en) * | 2014-09-03 | 2017-11-24 | 上海市青浦区中医医院 | A kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma and application thereof |
| CN104984054A (en) * | 2015-07-22 | 2015-10-21 | 袁玥 | Traditional Chinese medicine composition for treating asthma |
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2008
- 2008-11-12 CN CN2008102308473A patent/CN101406611B/en not_active Expired - Fee Related
Non-Patent Citations (7)
| Title |
|---|
| CNAA 2000.09.20 |
| 兰智慧 |
| 兰智慧;洪广祥.《支气管哮喘缓解期的中医药研究进展》.《实用中西医结合临床》.2002,第二卷(第1期),58-60. * |
| 张传名 |
| 张传名;王志英.《中医药治疗支气管哮喘进展》.《江西中医药》.2003,第11卷(第11期),46-48. * |
| 洪广祥.《支气管哮喘缓解期的中医药研究进展》.《实用中西医结合临床》.2002,第二卷(第1期),58-60. |
| 王志英.《中医药治疗支气管哮喘进展》.《江西中医药》.2003,第11卷(第11期),46-48. |
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| CN101406611A (en) | 2009-04-15 |
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