CN104189427B - A kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma and application thereof - Google Patents
A kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma and application thereof Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma, described Chinese medicine composition is made up of following bulk drug：Ephedra, cassia twig, semen armeniacae amarae, fritillaria thunbergii, Fructus Aurantii, cordate houttuynia, gingko, stiff silkworm, earthworm, the red sage root, balloonflower root, radix glycyrrhizae.Fang Zhong, it is Chinese ephedra, cassia twig expelling cold and relieving exterior syndrome, relieving cough and asthma, it is monarch drug in a prescription；Semen armeniacae amarae, fritillaria thunbergii, cordate houttuynia, Fructus Aurantii preventing phlegm from forming and stopping coughing, gingko lowering the adverse-rising QI to resolve phlegm, it is ministerial drug；Stiff silkworm, earthworm, the red sage root are promoting blood circulation and removing obstruction in channels, strengthen preventing phlegm from forming and stopping coughing, spasmolysis antiasthmatic effect, are adjutant；Radix glycyrrhizae QI invigorating is with, coordinating the drug actions of a prescription, and the expectoration of balloonflower root facilitaing lung, priming are up, to make medicine.The present invention also provides the application of the Chinese medicine composition.Clinical test shows that Chinese medicine composition of the invention has the effect of notable.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, is a kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma specifically
And application thereof.
Background technology
Cough is also known as coughed, and asthma, which also known as pants, stridulates, breathes heavily inverse, asthma drinks, upper gas etc., is the cardinal symptom performance of lung system disease.Outside
Feel six evil, internal organs internal injury causes functional disturbance, involved in lung, causes impairment of dispersing and descending function of the lung, Lung Qi upward reversal, then can occur or cough or
Asthma or the Symptoms of cough and asthma.Asthma is more also not to be terminated in not necessarily with cough, cough with asthma, right cough and asthma not from lung
Lung, there is " Lung Qi upward reversal " for its common interpretation of the cause, onset and process of an illness.
Cough and asthma is common in the infection of the upper respiratory tract alleged by modern medicine, bronchitis, bronchiectasis, pneumonia, pulmonary tuberculosis,
Pharyngitis, laryngitis, pertussis, bronchial astehma, asthmatic bronchitis, cardiac asthma, lung abscess, pleurisy, pulmonary emphysema, silicon
The diseases such as lung.
The opinion of cough and asthma starts from《Interior warp》.《Plain Questions cough opinion》Cloud：" lung makes us cough, He YeQi uncle is to saying:The vital organs of the human body
All make us cough, non-solely lung.”《Typhoid fever is fallen》Discuss cough card to control, can be summarized as cold cough and asthma, hot cough and asthma and phlegm and retained fluid cough and asthma three
Major class, face to demonstrate,prove to work as and distinguish cold and heat and asthenia and sthenia, treatment according to the specific symptoms.
《The Treatise on Fevrile Diseases》Provision 35：" Taiyin diseases, have a headache and fever, body pain, pain in the back, arthralgia, foul wind, no perspiration but asthma person,
Mahuang Tang master it ", i.e., Mahuang Tang side demonstrate,prove, provision 51 " floating pulse person, the disease being located in the exterior, can sweating, suitable Mahuang Tang ", provision 52 " floating pulse and
Number person, can sweating, declare Mahuang Tang " supplemented.The table of the main the whole body of the sun, the exterior tightened by pathogenic wind-cold, yang-energy is not stretched, therefore general aching on the body；
Sufficient TAI YANG pulse is supported in waist, therefore pain in the back；Event foul wind is obtained from chill；In outer, then fur closes chill visitor, therefore lossless；The sun is Zhu Yangzhu
Gas, yang-energy is strongly fragrant in interior, therefore breathes heavily；TAI YANG playing the role of vital function as a door, vertical Mahuang Tang open it, it is all card know except.
Chinese patent literature CN101979045A discloses a kind of medicine for treating cough illness, with lily, perillaseed, fish
Raw meat grass, almond, Radish seed, honeysuckle, rhizoma menispermi, balloonflower root, dandelion, radix glycyrrhizae, the sterculia seed, birthwort are raw material；By above-mentioned all medicines
It is put into marmite, by the 1 of bulk drug gross mass:2 add water to be cooked by slow fire, and 20 minutes after boiling, decoction is filtered out, then total by bulk drug
The 1 of quality:1 adds water to be cooked by slow fire, and 20 minutes after boiling, decoction is filtered out, and merges filtrate twice and bottles.Chinese patent literature
CN101342333B discloses a kind of Chinese medicine for treating cough and asthma, is made up of following bulk drugs：Reed rhizome, semen trichosanthis, Semen Benincasae, the heart of a lotus seed
Rice, honeysuckle, cordate houttuynia, sand ginseng, the fruit of Chinese magnoliavine, close moxibustion almond, gingko, close moxibustion radix glycyrrhizae, close moxibustion coltsfoot, close moxibustion aster, pericarpium citri grandis,
Balloonflower root, peach kernel, Semen Arecae (parched), Fructus Aurantii, cortex magnoliae officinalis, Divine Comedy, Endothelium Corneum Gigeriae Galli (parched), barrenwort, great Yun, stone reed.The present invention provides a kind of current
Chinese medicine composition for the treatment of wind-cold type disease of cough and asthma having not been reported and application thereof.
The content of the invention
The purpose of the present invention is to be directed to deficiency of the prior art, there is provided a kind of Chinese medicine group for treating wind-cold type disease of cough and asthma
Compound.
Another purpose of the present invention is to provide a kind of purposes for the Chinese medicine composition for treating wind-cold type disease of cough and asthma.
To achieve the above object, the present invention adopts the technical scheme that：A kind of Chinese medicine group for treating wind-cold type disease of cough and asthma
Compound, described Chinese medicine composition are made up of the bulk drug of following parts by weight：Ephedra 4-8 parts, cassia twig 4-8 parts, semen armeniacae amarae 7-
13 parts, fritillaria thunbergii 7-13 parts, Fructus Aurantii 7-13 parts, cordate houttuynia 25-35 parts, gingko 4-8 parts, stiff silkworm 4-8 parts, earthworm 7-13 parts, pellet
Join 7-13 parts, balloonflower root 4-8 parts, radix glycyrrhizae 4-8 parts.
Described Chinese medicine composition is made up of the bulk drug of following parts by weight：Ephedra 5-7 parts, cassia twig 5-7 parts, semen armeniacae amarae
9-11 parts, fritillaria thunbergii 9-11 parts, Fructus Aurantii 9-11 parts, cordate houttuynia 28-32 parts, gingko 5-7 parts, stiff silkworm 5-7 parts, earthworm 9-11 parts,
Red sage root 9-11 parts, balloonflower root 5-7 parts, radix glycyrrhizae 5-7 parts.
Described Chinese medicine composition is made up of the bulk drug of following parts by weight：6 parts of ephedra, 6 parts of cassia twig, semen armeniacae amarae 10
Part, 10 parts of fritillaria thunbergii, 10 parts of Fructus Aurantii, 30 parts of cordate houttuynia, 6 parts of gingko, 6 parts of stiff silkworm, 10 parts of earthworm, 10 parts of the red sage root, 6 parts of balloonflower root,
6 parts of radix glycyrrhizae.
To realize above-mentioned second purpose, the present invention adopts the technical scheme that：Described Chinese medicine composition is controlled in preparation
Treat the application in the medicine of wind-cold type disease of cough and asthma.
Described wind-cold type cough and asthma refers to the acute and chronic bronchitis of wind-cold type, bronchial astehma.
The invention has the advantages that：
The Chinese medicine composition of the present invention cures mainly wind-cold type cough and asthma, and clinical test shows there is the effect of notable.It can reduce
The use of antibiotic, the cure rate of acute cough and asthma is improved, reduce the attack times of chronic cough and asthma, improve the quality of life of patient.
Meet the principle of Chinese medicine monarch, have the advantages that to have no toxic side effect, be adapted to be widely popularized.
Embodiment
Embodiment provided by the invention is elaborated with reference to embodiment.
Wind-cold type cough and asthma（Acute and chronic bronchitis, bronchial astehma etc.）, it is lossless with fever with aversion to cold, cough and expectoration, cough up
Phlegm color white matter is dilute, and sound of the sputum in the throat, tongue nature is light red, and tongue is thin white, floating pulse count accurately based on want symptom.
A kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma, is made up of the bulk drug of following parts by weight：
Ephedra 4-8 parts, cassia twig 4-8 parts, semen armeniacae amarae 7-13 parts, fritillaria thunbergii 7-13 parts, Fructus Aurantii 7-13 parts, cordate houttuynia 25-
35 parts, gingko 4-8 parts, stiff silkworm 4-8 parts, earthworm 7-13 parts, red sage root 7-13 parts, balloonflower root 4-8 parts, radix glycyrrhizae 4-8 parts.
Fang Zhong, it is Chinese ephedra, cassia twig expelling cold and relieving exterior syndrome, relieving cough and asthma, it is monarch drug in a prescription；Semen armeniacae amarae, fritillaria thunbergii, cordate houttuynia, Fructus Aurantii resolving sputum
Cough-relieving, gingko lowering the adverse-rising QI to resolve phlegm, it is ministerial drug；Stiff silkworm, earthworm, the red sage root are promoting blood circulation and removing obstruction in channels, strengthen preventing phlegm from forming and stopping coughing, spasmolysis antiasthmatic effect, are
Adjutant；Radix glycyrrhizae QI invigorating is with, coordinating the drug actions of a prescription, and the expectoration of balloonflower root facilitaing lung, priming are up, to make medicine.
The Chinese medicine composition of embodiment 1
6 parts of ephedra, 6 parts of cassia twig, 10 parts of semen armeniacae amarae, 10 parts of fritillaria thunbergii, 10 parts of Fructus Aurantii, 30 parts of cordate houttuynia, 6 parts of gingko,
6 parts of stiff silkworm, 10 parts of earthworm, 10 parts of the red sage root, 6 parts of balloonflower root, 6 parts of radix glycyrrhizae.
The Chinese medicine composition of embodiment 2
5 parts of ephedra, 7 parts of cassia twig, 9 parts of semen armeniacae amarae, 11 parts of fritillaria thunbergii, 9 parts of Fructus Aurantii, 32 parts of cordate houttuynia, 5 parts of gingko, deadlock
7 parts of silkworm, 9 parts of earthworm, 11 parts of the red sage root, 5 parts of balloonflower root, 7 parts of radix glycyrrhizae.
The Chinese medicine composition of embodiment 3
7 parts of ephedra, 5 parts of cassia twig, 11 parts of semen armeniacae amarae, 9 parts of fritillaria thunbergii, 11 parts of Fructus Aurantii, 28 parts of cordate houttuynia, 7 parts of gingko, deadlock
5 parts of silkworm, 11 parts of earthworm, 9 parts of the red sage root, 7 parts of balloonflower root, 5 parts of radix glycyrrhizae.
The Chinese medicine composition of embodiment 4
4 parts of ephedra, 8 parts of cassia twig, 7 parts of semen armeniacae amarae, 13 parts of fritillaria thunbergii, 7 parts of Fructus Aurantii, 35 parts of cordate houttuynia, 4 parts of gingko, deadlock
8 parts of silkworm, 7 parts of earthworm, 13 parts of the red sage root, 4 parts of balloonflower root, 8 parts of radix glycyrrhizae.
The Chinese medicine composition of embodiment 5
8 parts of ephedra, 4 parts of cassia twig, 13 parts of semen armeniacae amarae, 7 parts of fritillaria thunbergii, 13 parts of Fructus Aurantii, 25 parts of cordate houttuynia, 8 parts of gingko, deadlock
4 parts of silkworm, 13 parts of earthworm, 7 parts of the red sage root, 8 parts of balloonflower root, 4 parts of radix glycyrrhizae.
The preparation of the Chinese medicine composition of embodiment 6
Any described Chinese medicine compositions of embodiment 1-5, are decocted with water 1000ml, boil and take 400ml, point sooner or later 2 times it is oral,
Warmly take after meal.
The preparation of the Chinese medicine composition of embodiment 7
Any described Chinese medicine compositions of embodiment 1-5 prepare any agent pharmaceutically allowed by conventional formulation means
Type, such as granule, capsule, tablet, pill, oral liquid etc..
The clinical test of embodiment 8
1. general information
100 wind-cold type cough and asthma patients that the court is accepted for medical treatment during in December, 1 to 2013 in 2012 are randomly divided into two groups of progress
Treatment, each 50 of every group of patient, wherein treatment group man 45, female 5,12~70 years old age, average age 41.5 years old, the course of disease 2
~36 years；Control group man 44, female 6,16~72 years old age, average age 43.6 years old, the course of disease 2~38 years；Two groups of patients'
The ordinary circumstance no significant difference such as sex, age（P ＞ 0. 05）, there is comparativity.
2. diagnostic criteria
Chinese medical discrimination diagnoses wind-cold type cough and asthma, and lossless with fever with aversion to cold, cough and expectoration, color white matter of coughing up phlegm is dilute, phlegm sound between larynx
Filter, tongue nature is light red, and tongue is thin white, floating pulse count accurately based on want symptom.
3. treatment method
Treatment group：The Chinese medicine composition of embodiment 1, decocted with water 1000ml, boil and take 400ml, 2 oral, meals of point morning and evening
After warmly take.7 days are 1 course for the treatment of, continuously take 5 courses for the treatment of.
Control group：Using the method for Western medicine symptomatic treatment：Antibiotic amoxycillin or tight enlightening etc. are simultaneously given to the ill
It is relieving cough and asthma to wait medicine.Instructions of taking：Amoxycillin 0.5g, 4 times/d, Yan Di 150mg/ times, 2 times/d；As asthma can notably give
Give aminophylline 0.1g/ times, 3 times/d；Abundant expectoration person gives brown mixture and fritillary bulb cough syrup.7 days are 1 course for the treatment of, continuously
Take 5 courses for the treatment of.
4. statistical method
Data processing is carried out using SPSS13.0 statistics softwares, measurement data is represented using mean ± standard deviation, between group
Compare and apply χ2Examine, be that difference has statistical significance with P ＜ 0.05.
5. curative effect determinate standard
1. clinic control：Patient pants, coughed, the clinical symptom disappearance such as auscultation of lung wheezing sound or basic after treatment
Disappear.It is 2. effective：After treatment, the clinical symptoms such as cough and asthma and sign are obviously improved.It is 3. effective：Cough and asthma symptom substantially mitigates, and has one
Determine the improvement of degree.It is 4. invalid：Clinical symptoms are not improved with indexs such as signs.
6. index determining
Before and after treatment using Immunity transmission turbidity detection serum immune globulin IgA, IgG, IgM contain two groups of patients
Amount, and be analyzed.
7. result
7.1 two groups of patient's curative effects compare
There is not significant discomfort case in treatment group in therapeutic process.Two groups of wind-cold type cough and asthma patients are by 5 courses for the treatment of
After treatment, treatment group's total effective rate is 94%, and control group total effective rate is 66%, and the total effective rate difference of two groups of patients has statistics
Learn meaning（P ＜ 0.05）.The effect of illustrating treatment group is shown in Table 1 apparently higher than control group, concrete outcome.
The effect for the treatment of group of table 1 and control group, contrasts
The IgA of immunoglobulin, IgG, the analysis of IgM content balances after 7.2 two groups of patient's treatments
After treatment by 5 courses for the treatment of, treatment group's patient's Immunoglobulin IgA, IgG's, IgM is horizontal apparently higher than control
Group, difference have statistical significance（P ＜ 0.05）, the results are shown in Table 2.
Immunoglobulin contrasts after 2 two groups of patient's treatments of table
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as
Protection scope of the present invention.
Claims (3)
1. a kind of Chinese medicine composition for treating wind-cold type disease of cough and asthma, it is characterised in that described Chinese medicine composition is by following heavy
The bulk drug of amount part is made：6 parts of ephedra, 6 parts of cassia twig, 10 parts of semen armeniacae amarae, 10 parts of fritillaria thunbergii, 10 parts of Fructus Aurantii, 30 parts of cordate houttuynia,
6 parts of gingko, 6 parts of stiff silkworm, 10 parts of earthworm, 10 parts of the red sage root, 6 parts of balloonflower root, 6 parts of radix glycyrrhizae.
2. application of the Chinese medicine composition according to claim 1 in the medicine for preparing treatment wind-cold type disease of cough and asthma.
3. application according to claim 2, it is characterised in that described wind-cold type cough and asthma refers to the acute and chronic branch of wind-cold type
Tracheitis, bronchial astehma.
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| CN110575505A (en) * | 2019-09-09 | 2019-12-17 | 首都医科大学附属北京朝阳医院 | Medicine for treating acute bronchitis and acute attack of chronic bronchitis and preparation method and application thereof |
Citations (4)
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|---|---|---|---|---|
| CN101342333A (en) * | 2008-08-14 | 2009-01-14 | 张然周 | Traditional Chinese medicine for treating cough and asthma and preparation method thereof |
| CN101406611A (en) * | 2008-11-12 | 2009-04-15 | 宋红鑫 | Chinese medicine preparation for treating bronchial asthma |
| CN103142965A (en) * | 2013-03-26 | 2013-06-12 | 谢银芳 | Traditional Chinese medicine preparation for treating cold drink type children bronchial asthma |
| CN103784555A (en) * | 2012-10-29 | 2014-05-14 | 刘黎明 | Traditional Chinese medicine aerosol used for preventing and treating children cold asthma |
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2014
- 2014-09-03 CN CN201410445264.8A patent/CN104189427B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342333A (en) * | 2008-08-14 | 2009-01-14 | 张然周 | Traditional Chinese medicine for treating cough and asthma and preparation method thereof |
| CN101406611A (en) * | 2008-11-12 | 2009-04-15 | 宋红鑫 | Chinese medicine preparation for treating bronchial asthma |
| CN103784555A (en) * | 2012-10-29 | 2014-05-14 | 刘黎明 | Traditional Chinese medicine aerosol used for preventing and treating children cold asthma |
| CN103142965A (en) * | 2013-03-26 | 2013-06-12 | 谢银芳 | Traditional Chinese medicine preparation for treating cold drink type children bronchial asthma |
Non-Patent Citations (1)
| Title |
|---|
| 麻黄地龙汤治疗支气管哮喘53例疗效观察;喻平瀛，金永祥;《甘肃中医》;19950630;第8卷(第03期);第13-14页 * |
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