CN1927277A - Traditional Chinese medicine composition for psoriasis - Google Patents

Traditional Chinese medicine composition for psoriasis Download PDF

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Publication number
CN1927277A
CN1927277A CNA2006101128686A CN200610112868A CN1927277A CN 1927277 A CN1927277 A CN 1927277A CN A2006101128686 A CNA2006101128686 A CN A2006101128686A CN 200610112868 A CN200610112868 A CN 200610112868A CN 1927277 A CN1927277 A CN 1927277A
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CN
China
Prior art keywords
parts
radix
chinese medicine
preparation
periostracum
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Pending
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CNA2006101128686A
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Chinese (zh)
Inventor
杨小懿
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Beijing Rundekang Medical Technology Co Ltd
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Beijing Rundekang Medical Technology Co Ltd
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Priority to CNA2006101128686A priority Critical patent/CN1927277A/en
Publication of CN1927277A publication Critical patent/CN1927277A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a Chinese medicinal composition and process for preparation, in particular a composition for the treatment of various psoriasis. The composition can be made into clinically needed dose forms.

Description

A kind ofly be used for psoriatic Chinese medicine composition
Technical field:
The present invention relates to a kind of Chinese medicine composition and preparation technology thereof, particularly a kind of all kinds psoriasis that is used for, the prescription and the preparation technology thereof of diseases such as the skin lesion desquamation of course of disease outbreak repeatedly of a specified duration, pruritus.
Background technology:
All kinds psoriasis, the course of disease more repeatedly diseases such as the skin lesion desquamation of outbreak, pruritus be clinically to see that symptom, the traditional Chinese medical science are often taked clearing away heat and cooling blood, the antidotal means of dispeling the wind are treated it more, and evident in efficacy.But shortcomings such as in the practice, onset is slow because many Chinese medicines have, the course of treatment is long have a strong impact on its clinical practice.
Chinese medicine composition of the present invention can collect the elite and thick the putting of medicine, is easy to dissolving and absorption, and curative effect is fast, and administration time is short, and therefore, curative effect is better.
The purpose of this invention is to provide a kind of all kinds psoriasis that is used for, the pure Chinese medicine composition and the multiple appropriate formulation thereof of diseases such as the skin lesion desquamation of course of disease outbreak repeatedly of a specified duration, pruritus, said preparation is rapid-action, evident in efficacy, is worthy of popularization.
Summary of the invention:
The present invention relates to a kind of prescription and preparation technology thereof of Chinese medicine preparation, it is characterized in that, the preparation of per 1000 dosage units in basic side is prepared from by following proportion raw material:
15~60 parts of 100~400 portions of Periostracum Cicadaes of 225~900 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
10~40 parts of 25~100 parts of Scolopendras of 10~40 parts of Indigo Naturaliss of Periostracum Serpentis
15~60 parts of stir-baked SQUAMA MANITISs.
Preferably:
30 parts of 200 portions of Periostracum Cicadaes of 450 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
20 parts of 50 parts of Scolopendras of 20 parts of Indigo Naturaliss of Periostracum Serpentis
30 parts of stir-baked SQUAMA MANITISs.
The preparation of per 1000 dosage units of the present invention side of deriving a is prepared from by following proportion raw material:
15~60 parts of 100~400 portions of Periostracum Cicadaes of 225~900 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
10~40 parts of 25~100 parts of Scolopendras of 10~40 parts of Indigo Naturaliss of Periostracum Serpentis
25~100 parts of 100~400 parts of Radix Et Rhizoma Rhei of 15~60 parts of Cortex Lycii of stir-baked SQUAMA MANITIS
25~100 parts of 25~100 parts of Radix Saposhnikoviaes of 25~100 parts of Flos Carthamis of Radix Arnebiae (Radix Lithospermi).
Preferably:
30 parts of 200 portions of Periostracum Cicadaes of 450 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
20 parts of 50 parts of Scolopendras of 20 parts of Indigo Naturaliss of Periostracum Serpentis
50 parts of 200 parts of Radix Et Rhizoma Rhei of 30 parts of Cortex Lycii of stir-baked SQUAMA MANITIS
50 parts of 50 parts of Radix Saposhnikoviaes of 50 parts of Flos Carthamis of Radix Arnebiae (Radix Lithospermi).
The preparation of per 1000 dosage units of the present invention side of deriving b is prepared from by following proportion raw material:
15~60 parts of 100~400 portions of Periostracum Cicadaes of 225~900 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
10~40 parts of 25~100 parts of Scolopendras of 10~40 parts of Indigo Naturaliss of Periostracum Serpentis
5.5~22 parts of stir-baked SQUAMA MANITIS 100~400 parts of Sal Nitris of 15~60 parts of Cortex Lycii (Sal Nitri)
25~100 parts on 25~100 parts of Flos Carthamis of Radix Arnebiae (Radix Lithospermi).
Preferably:
30 parts of 200 portions of Periostracum Cicadaes of 450 parts of Rhizoma Fagopyri Dibotryiss of Radix Sophorae Flavescentis
20 parts of 50 parts of Scolopendras of 20 parts of Indigo Naturaliss of Periostracum Serpentis
11 parts of stir-baked SQUAMA MANITIS 200 parts of Sal Nitris of 30 parts of Cortex Lycii (Sal Nitri)
50 parts on 50 parts of Flos Carthamis of Radix Arnebiae (Radix Lithospermi).
In more than forming, the weight of medicine is calculated with crude drug, and per 1 part can be 1 gram, also can be kilogram or ton, if be unit with gram, this prescription composition can be made into 1000 doses of pharmaceutical preparatioies.Described 1000 doses of fingers, the final drug preparation of making, as make granule 1000g etc., also can make big packing as granule, as 100~500 bags, specifically can be 100 bags, 125 bags, 200 bags, 250 bags, 500 bags etc., every bag can be used as taking dose 1 time.
More than form, can be made into the preparation of 50~1000 taking doses,, make 125 bags, take 1~2 bag at every turn, can take altogether 62.5~125 times as granule.
More than form to be by weight as proportioning, when producing, can or reduce according to the corresponding proportion increase, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The raw material of Chinese medicine of said ratio extracts processing through new technology of the present invention, obtain the active constituents of medicine of preparation of the present invention, add suitable excipient as required and make suitable medicinal any dosage form, said preparation can be multiple suitable dosage forms such as capsule, granule, tablet, powder.
The specific embodiment:
Further specify the present invention by the following examples, include but not limited to the following example.
Embodiment 1:
The preparation method of granule of the present invention:
Prescription:
Radix Sophorae Flavescentis 450g Rhizoma Fagopyri Dibotryis 200g Periostracum Cicadae 30g
Periostracum Serpentis 20g Indigo Naturalis 50g Scolopendra 20g
Stir-baked SQUAMA MANITIS 30g
Make 1000g
Preparation method:
(1) get Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, add aspartame 5.0g, dextrin 200.0g, granulate, drying sprays into essence 5.0g, promptly gets granule 1000g.
Embodiment 2:
The preparation method of capsule of the present invention:
Prescription:
Radix Sophorae Flavescentis 450g Rhizoma Fagopyri Dibotryis 200g Periostracum Cicadae 30g
Periostracum Serpentis 20g Indigo Naturalis 50g Scolopendra 20g
Stir-baked SQUAMA MANITIS 30g
Make 1000
Preparation method:
(1) get Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, dry, be made into 1000 of capsules according to the pharmaceutics routine techniques.
Embodiment 3:
The preparation method of tablet of the present invention:
Prescription:
Radix Sophorae Flavescentis 450g Rhizoma Fagopyri Dibotryis 200g Periostracum Cicadae 30g
Periostracum Serpentis 20g Indigo Naturalis 50g Scolopendra 20g
Stir-baked SQUAMA MANITIS 30g
Make 1000
Preparation method:
(1) get Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, dry, be made into 1000 in tablet according to the pharmaceutics routine techniques.

Claims (8)

1, a kind ofly is used for psoriatic Chinese medicine preparation, it is characterized in that: according to weight proportion, it is by Radix Sophorae Flavescentis 225~900, Rhizoma Fagopyri Dibotryis 100~400, Periostracum Cicadae 15~60, Periostracum Serpentis 10~40, Indigo Naturalis 25~100, Scolopendra 10~40, stir-baked SQUAMA MANITIS 15~60 are for basic side or be equipped with other Chinese medicines and generate the sides of deriving and be made.
2, the Chinese medicine preparation of claim 1 is characterized in that, described basic side's proportioning is: 450 parts of Radix Sophorae Flavescentiss, 200 parts of Rhizoma Fagopyri Dibotryiss, 30 parts of Periostracum Cicadaes, 20 parts of Periostracum Serpentiss, 50 parts of Indigo Naturaliss, 20 parts of Scolopendras, 30 parts of stir-baked SQUAMA MANITISs.
3, the Chinese medicine preparation of claim 1 is characterized in that, the proportioning of the described side of deriving is:
The basic side of A adds 200 parts of Cortex Lycii, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Radix Arnebiae (Radix Lithospermi)s, 50 parts on Flos Carthami, 50 parts of Radix Saposhnikoviaes;
The basic side of B adds 200 parts of Cortex Lycii, 11 parts of Sal Nitris (Sal Nitri), 50 parts of Radix Arnebiae (Radix Lithospermi)s, 50 parts on Flos Carthami, 44 parts of Rhizoma Et Radix Notopterygiis.
4, the Chinese medicine preparation of claim 1 is characterized in that, is described raw material of Chinese medicine is extracted processing, obtains active component, adds suitable adjuvant as required, makes clinical needed dosage form with the galenic pharmacy routine techniques.
5, the Chinese medicine preparation of claim 4 is characterized in that:
The preparation process of described granule is as follows: with above-mentioned extract obtained, add a certain amount of filler, correctives, lubricant, granulate, promptly get granule;
The preparation method of tablet is as follows: with above-mentioned extract obtained, adds a certain amount of filler, correctives, lubricant, disintegrating agent, granulates, and drying, tabletting promptly gets tablet.
6, the Chinese medicine preparation of claim 5 is characterized in that:
Described filler is selected from one or more the mixture in lactose, sucrose, dextrin, starch, microcrystalline Cellulose, mannitol, pregelatinized Starch, sorbitol, the xylitol etc.;
Described correctives one of is selected from Rhizoma et radix valerianae, Fructus Pruni pseudocerasi, Fructus Vitis viniferae, Fructus Citri tangerinae, Fructus Citri Limoniae, Herba Menthae, Fructus Fragariae Ananssae, Fructus Musae, Fructus Ananadis comosi, honey peach essence, maltose alcohol, saccharin sodium, protein sugar, sucrose, aspartame, the stevioside or wherein several mixture;
Suitable lubricant comprises wherein one or more such as magnesium stearate, Pulvis Talci, micropowder silica gel.
7, the preparation method of claim 6 is characterized in that: the prescription of the preparation of making is respectively:
The a Radix Sophorae Flavescentis, Rhizoma Fagopyri Dibotryis, Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS;
The b Radix Sophorae Flavescentis, Rhizoma Fagopyri Dibotryis, Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS, Cortex Lycii, Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Flos Carthami, Radix Saposhnikoviae;
The c Radix Sophorae Flavescentis, Rhizoma Fagopyri Dibotryis, Periostracum Cicadae, Periostracum Serpentis, Indigo Naturalis, Scolopendra, stir-baked SQUAMA MANITIS, Cortex Lycii, Sal Nitri (Sal Nitri), Radix Arnebiae (Radix Lithospermi), Flos Carthami.
8, the Chinese medicine preparation of claim 1 is in preparation treatment all kinds psoriasis, the application in the medicine of diseases such as the skin lesion desquamation of course of disease outbreak repeatedly of a specified duration, pruritus.
CNA2006101128686A 2006-09-06 2006-09-06 Traditional Chinese medicine composition for psoriasis Pending CN1927277A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2006101128686A CN1927277A (en) 2006-09-06 2006-09-06 Traditional Chinese medicine composition for psoriasis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2006101128686A CN1927277A (en) 2006-09-06 2006-09-06 Traditional Chinese medicine composition for psoriasis

Publications (1)

Publication Number Publication Date
CN1927277A true CN1927277A (en) 2007-03-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006101128686A Pending CN1927277A (en) 2006-09-06 2006-09-06 Traditional Chinese medicine composition for psoriasis

Country Status (1)

Country Link
CN (1) CN1927277A (en)

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Application publication date: 20070314