CN1922205A - 甘丙肽受体与脑部损伤 - Google Patents

甘丙肽受体与脑部损伤 Download PDF

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Publication number
CN1922205A
CN1922205A CNA2005800051943A CN200580005194A CN1922205A CN 1922205 A CN1922205 A CN 1922205A CN A2005800051943 A CNA2005800051943 A CN A2005800051943A CN 200580005194 A CN200580005194 A CN 200580005194A CN 1922205 A CN1922205 A CN 1922205A
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CN
China
Prior art keywords
galr2
pharmaceutical composition
composition according
damage
specific agonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800051943A
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English (en)
Chinese (zh)
Inventor
D·温尼克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurotargets Ltd
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Neurotargets Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurotargets Ltd filed Critical Neurotargets Ltd
Publication of CN1922205A publication Critical patent/CN1922205A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Addiction (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
CNA2005800051943A 2004-02-17 2005-01-18 甘丙肽受体与脑部损伤 Pending CN1922205A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403509.3A GB0403509D0 (en) 2004-02-17 2004-02-17 Galanin receptors and brain injury
GB0403509.3 2004-02-17

Publications (1)

Publication Number Publication Date
CN1922205A true CN1922205A (zh) 2007-02-28

Family

ID=32039889

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800051943A Pending CN1922205A (zh) 2004-02-17 2005-01-18 甘丙肽受体与脑部损伤

Country Status (8)

Country Link
US (2) US20080020975A1 (https=)
EP (1) EP1723175A1 (https=)
JP (1) JP2008501632A (https=)
CN (1) CN1922205A (https=)
AU (1) AU2005214115B2 (https=)
CA (1) CA2555550A1 (https=)
GB (1) GB0403509D0 (https=)
WO (1) WO2005080427A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105246502A (zh) * 2013-07-05 2016-01-13 复苏技术有限责任公司 用于防止或减少脑和全身再灌注损伤的保护液
CN106880837A (zh) * 2015-12-15 2017-06-23 北京脑重大疾病研究院 一种甘丙肽在制备防止缺血性脑卒的试剂中的应用
CN108348570A (zh) * 2015-11-30 2018-07-31 纽洛可科学有限公司 基于spexin的甘丙肽2型受体激动剂及其用途

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047302A1 (en) 2004-10-21 2006-05-04 Transtech Pharma, Inc. Bissulfonamide compounds as agonists of galr1, compositions, and methods of use
GB0523550D0 (en) 2005-11-18 2005-12-28 Hunter Fleming Ltd Therapeutic uses of steroidal compounds
WO2008086573A1 (en) * 2007-01-19 2008-07-24 Howard Florey Institute Of Experimental Physiology And Medicine Use of galanin in a method of treating neurodegenerative diseases or conditions
JP5570996B2 (ja) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド エアロゾル化可能な食料品の送達
WO2012051567A2 (en) 2010-10-15 2012-04-19 The Trustees Of Columbia University In The City Of New York Obesity-related genes and their proteins and uses thereof
KR101514440B1 (ko) * 2013-12-13 2015-04-22 고려대학교 산학협력단 갈라닌 수용체 3형의 리간드로서 스펙신의 용도
US10314911B2 (en) 2014-04-08 2019-06-11 Healthpartners Research & Education Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin
ES2707210B2 (es) 2017-10-02 2020-09-30 Univ Malaga GAL(1-15) y análogos de la misma para uso en la prevención y/o tratamiento de trastornos y efectos relacionados con el alcohol.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972624A (en) * 1996-01-24 1999-10-26 Synaptic Pharmaceutical Corporation Method of identifying ligands which bind recombinant galanin receptor (GALR2)
AU730137B2 (en) * 1996-01-24 2001-03-01 H. Lundbeck A/S DNA encoding galanin GALR2 receptors and uses thereof
DE69739760D1 (de) * 1996-07-24 2010-03-25 Neurotargets Ltd Verwendung eines Galanin-agonisten in der Herstellung eines Medikaments zur Verbesserung des Gedächtnisses und anderer cognitiver Funktionen
CA2282662A1 (en) * 1996-12-27 1998-07-09 Merck & Co., Inc. Human galanin receptor galr2 and nucleotides encoding same
US6337206B1 (en) * 1997-12-18 2002-01-08 Merck & Co., Inc. Nucleic acid encoding mouse galanin receptor (GALR2)
WO2002096934A1 (en) * 2001-05-25 2002-12-05 Kemia, Inc. Non-natural galanin receptor ligands

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105246502A (zh) * 2013-07-05 2016-01-13 复苏技术有限责任公司 用于防止或减少脑和全身再灌注损伤的保护液
CN108348570A (zh) * 2015-11-30 2018-07-31 纽洛可科学有限公司 基于spexin的甘丙肽2型受体激动剂及其用途
CN108348570B (zh) * 2015-11-30 2022-05-03 纽洛可科学有限公司 基于spexin的甘丙肽2型受体激动剂及其用途
CN106880837A (zh) * 2015-12-15 2017-06-23 北京脑重大疾病研究院 一种甘丙肽在制备防止缺血性脑卒的试剂中的应用

Also Published As

Publication number Publication date
US20100184638A1 (en) 2010-07-22
EP1723175A1 (en) 2006-11-22
CA2555550A1 (en) 2005-09-01
WO2005080427A1 (en) 2005-09-01
AU2005214115B2 (en) 2010-08-12
AU2005214115A1 (en) 2005-09-01
JP2008501632A (ja) 2008-01-24
GB0403509D0 (en) 2004-03-24
US20080020975A1 (en) 2008-01-24

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Application publication date: 20070228