CN1903209A - Weight-reducing compound prepn. and its prepn. method - Google Patents
Weight-reducing compound prepn. and its prepn. method Download PDFInfo
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- CN1903209A CN1903209A CN 200510010228 CN200510010228A CN1903209A CN 1903209 A CN1903209 A CN 1903209A CN 200510010228 CN200510010228 CN 200510010228 CN 200510010228 A CN200510010228 A CN 200510010228A CN 1903209 A CN1903209 A CN 1903209A
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Abstract
A compound medicine for losing weight is proportionally prepared from levocarnitine, oligoisomaltose and purified water through heating purified water to 45-80 deg.C, adding oligoisomaltose, stirring for dissolving, filtering, adding the aqueous solution of levocarnitine, stirring and adding purified water.
Description
Technical field:
The present invention relates to a kind of compound preparation that can promote body fat metabolism, fat-reducing and preparation method thereof.
Background technology:
Current society, fat crowd is more and more, and fat people's life, work and the health of giving has all been brought harmful effect.Obesity is the root of diseases such as hyperlipidemia, diabetes, apoplexy, fatty liver, hypertension and increases the weight of factor.Some common slimming preparations lose weight by following approach mostly on the market:
1. utilize the medicine appetite-suppressing that acts on the central nervous system, reach slimming purpose by reducing the absorption diet, this method tends to cause malnutrition, hepar damnification, some easy addiction or generation psychic dependence.Indivedual medicines have been under an embargo abroad and have produced and use because cause the impaired death of user cardiac valve.
2. contain hormone, promote body metabolism and protein to decompose and increase consume and reach slimming purpose.Life-time service can cause the human endocrine disorder, has endless trouble.
3. contain cathartic and diuretic, drain by increasing, venting human body normal body fluid often causes the random and dehydration of cylinder electrolyte wadding by force.
4. form by stodgy Plant fiber, full sense is arranged behind the clothes.Easily cause malnutrition and constipation, cause immunity of organisms to descend.
After taking above-mentioned slimming preparation, people often think deduct be fat, comprise moisture, fat and protein etc. in the composition that deducts in fact.The side effect that has obviously or poor effect, and follow cutis laxa appears, coarse, wrinkle increases.After cutting out these slimming preparations, fat can get up (bounce-back) in run-up, and the muscle that loses but is not restored.
Summary of the invention: the purpose of this invention is to provide a kind of not anorexia, not weak, do not suffer from diarrhoea Jian Fei compound preparation and preparation method thereof safely and effectively
Above-mentioned purpose realizes by following technical scheme:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the ratio of weight and number of described L-carnitine and described oligomeric isomaltose are 5～20: 50～90.
The compound preparation of above-mentioned fat-reducing, the compound preparation of described fat-reducing contains citric acid, acesulfame potassium, edible essence, the weight fraction of described citric acid is than 5～20, and the ratio of weight and number of described acesulfame potassium is 0.3～5, and the ratio of weight and number of described edible essence is 1～4.
The preparation method of the compound preparation of fat-reducing, L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, the adding parts by weight are 4000～4500 pure water in the ingredients jar, open Steam Heating to 45 ℃～80 ℃, drop into the oligomeric isomaltose of above-mentioned parts by weight, stirring makes it to dissolve fully, filter, L-carnitine is dissolved in the pure water, joins mix homogeneously in the oligomeric isomaltose solution after the filtration, add pure water to parts by weight 5000, detection level is qualified, sterilization, product is made in fill.
The preparation method of the compound preparation of above-mentioned fat-reducing, in described mixed solution, add described citric acid, acesulfame potassium, edible essence, the weight fraction of described citric acid is than 5～20, and the ratio of weight and number of described acesulfame potassium is 0.3～5, and the ratio of weight and number of described edible essence is 1～4, stir, add pure water to parts by weight 5000, detection level is qualified, sterilization, product is made in fill.
This technical scheme has following beneficial effect:
1. scientific formulation of the present invention is reasonable, constitutes prescription by L-carnitine, oligomeric isomaltose, has stronger antiobesity action by mutual synergism.Add L-carnitine and the following synergism of oligomeric isomaltose generation in the prescription:
(1) the activatory long-chain fatty acid of transhipment is passed mitochondrial inner membrane, enters the mitochondrial matrix of tryptophan side-chain alpha system activity, promotes oxidation of fatty acids to decompose energy supply, forms fine fat-reducing active substance.
(2) significantly reduce the ratio of acyl coenzyme A/ coenzyme acid A, promote the activity of pyruvic dehydrogenase, promote the oxidation utilization of glucose.
(3) save free coenzyme A, increase the amount of tricarboxylic acid cycle, obviously promote aerobic metabolism.
(4) effectively remove too much lactic acid, improve the acting ability, promote fatigue recovery.
(5) promote the aminolysis toxic action, recover sports fatigue.
By adding oligomeric isomaltose, increase the increment factor of topmost probiotics one bifid bacillus in the human body intestinal canal.This makes the present invention can improve function of intestinal canal, promote enterokinesia, loosening bowel to relieve constipation, reduce toxicity in the intestinal, suppress the growth of putrefaction bacteria, reduce the formation of harmful substance, alleviate burden of liver, reduce the quantity of blood cholesterol, glycerol, free fatty, eliminate and improve the source of disease of obesity, improve body immunity.
2. product of the present invention is compared with product in the past as the compound preparation of fat-reducing, do not contain hormone, not appetite-suppressing, do not suffer from diarrhoea, addiction, nontoxic not, safe and effective, have no side effect taking convenience, do not rebound after the fat-reducing, really cut unnecessary fat of human body and irritating proud flesh.
3. bacillus bifidus is most important to health.As everyone knows, breast-feeding infant is fed youngster's health than milk replacer, and the former resistance against diseases is strong, this also gives the credit to and contains functional oligomeric isomaltose in the breast milk, bacillus bifidus is in the absolute advantages status in the breast-feeding infant intestinal, accounts for 99% of total bacteria count, and the latter only accounts for 50% or still less.Along with the increase at age, the bacillus bifidus ratio in the intestinal will reduce year by year, and this trend is particularly evident on one's body senile old man.The major reason that the minimizing of bifidobacteria viable bacteria is considered to is old and feeble, immunity of organism descends and adult diseases such as cancer, arthritis take place.The flora structure is similar to the adolescent in the long road of long lived elder, and bacillus bifidus is still preponderated, and makes bacillus bifidus keep this advantage for a long time at human body by product absorption oligomeric isomaltose of the present invention and L-carnitine.The bacillus bifidus of advantage can strengthen body immunity, improves the absorption rate of human body to calcium, alleviates liver and divides the burden of toxolysin and reduce diarrhoea and the constipation generation.
The product of the application of the invention, take in after functional oligomeric isomaltose and the L-carnitine, effect with the value of bringing high blood pressure down, through testing: 46 hyperpietics take in a certain amount of 5 weeks of oligomeric isomaltose every day, its diastole flattens the 6mmHg that all descends, allow 6 28-48 year take in a certain amount of oligomeric isomaltose a healthy continuous week of adult male, its diastole flattens and all reduces 6.3mmHg.Studies show that further the ratio that a people's diastole presses bacillus bifidus number in height and the feces to account for total bacteria count is tangible negative correlativing relation.
The product of the present invention that contains oligomeric isomaltose and L-carnitine, safe and reliable, stable in properties, chemical constitution are clear and definite, hygiogenesis is clear, its stability is particularly outstanding, even all can not decompose for the human body digestive enzyme, therefore suitable effect substrate that neither oral microorganism uses oligomeric isomaltose not cause the shortcoming of fat and dental caries.Active substance among the present invention belongs to water soluble dietary fiber, but is better than general dietary fiber, mainly contains following advantage: " the daily demand that (1) is less only needs about 3g usually every day.(2) in the recommended amounts scope, can not cause diarrhoea.(3) have certain sweet taste, sweet taste characteristic is good, does not have unfavorable organizational structure or mouthfeel characteristic.(4) soluble in water, do not increase the viscosity of product.(5) physical property is stable, not the chelate mineral element.(6) be easy to insert in processed food and the beverage.”
In sum, product of the present invention has health-care effect widely, almost men and women, old and young everybody is all suitable, be very suitable so it is used as the compound preparation of fat-reducing.
4. safety
Entrust " Heilongjiang Province's public health inspection center " that this preparation has been done the test of safety toxicological evaluation, result of the test is: per os acute toxicity test LD
50Greater than 21.5ml/kgBW, this preparation belongs to actual innocuous substance; Three genetic toxicity tests such as Salmonella reversion test, mouse bone marrow cells micronucleus test and the test of mouse sperm distortion analysis detect all negative, and 30 days feeding trials do not see that it has any toxicity damage effect to animal.
Entrust " Nutrition and Food Safety Office of China Disease Prevention and control Centre " that this preparation is carried out the weight losing function animal experiment, with 1.25,3.75, this product of 6.25ml/kgBW dosage irritates stomach and gives rat after 30 days, each dosage group and model control group compare, and there are no significant for animal food-intake difference (P＞0.05); 6.25ml/kgBW dosage treated animal test back body weight, weight gain, body constitution increment, body fat/weight ratio all are lower than model control group, difference all has significance (P＜0.05).Therefore show that the weight losing function animal test results of this product is positive.
Entrust " health Institute of Analysis of Shandong University " (health food inspection body that Ministry of Public Health is assert) that this preparation has been done the weight losing function human experimentation, the continuous drinking of said product of test group experimenter is after 45 days, experimental group experiment back weight average decline 2.4Kg, body fat weight decline 2.4Kg, the fat percentage rate descends 2.2%, the waistline 3.8cm that on average descends, hip circumference decline 1.7cm, subcutaneous fat thickness all descends, wherein the triangular muscle lower edge reduces 2mm, and the angulus inferior scapulae place reduces 5mm, and the other place of umbilicus reduces 4mm, the anterior superior iliac spine place reduces 3mm, with comparing difference before the experiment explicitly (P＜0.01) is arranged all.Experiment back test group body fat weight, fatty percentage rate, waistline, angulus inferior scapulae place, the other place of umbilicus subcutaneous fat thickness all are lower than matched group, and difference all has significance (P＜0.05).Spirit, sleep, diet, defecation, blood pressure, every clinical health check-up index the experimental session experimenter there is no unusually, and exercise tolerance does not descend, and does not see other untoward reaction.The experimenter is in the diet of experimental session and motion conditions and the daily consistent influence of getting rid of diet and exercise factor to experimental result.This shows that this product has tangible weight losing function to human body, and body health is had no adverse effects.
The specific embodiment of the present invention:
Embodiment 1:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the parts by weight of described L-carnitine are 5 grams, the parts by weight of described oligomeric isomaltose are 50 grams.
Its preparation method is: L-carnitine, the oligomeric isomaltose of getting above-mentioned weight are standby, add the 4000ml pure water in the ingredients jar, open Steam Heating to 45 ℃, drop into the oligomeric isomaltose of above-mentioned deal, stirring makes it to dissolve fully, filters, and L-carnitine is dissolved in the pure water, join mix homogeneously in the oligomeric isomaltose solution after the filtration, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 2:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the parts by weight of described L-carnitine are 6 grams, the parts by weight of described oligomeric isomaltose are 80 grams.
Its preparation method is: L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, add the 4300ml pure water in the ingredients jar, open Steam Heating to 50 ℃, drop into the oligomeric isomaltose of above-mentioned weight, stirring makes it to dissolve fully, filters, and L-carnitine is dissolved in the pure water, join mix homogeneously in the oligomeric isomaltose solution after the filtration, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 3:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the parts by weight of described L-carnitine are 16 grams, the parts by weight of described oligomeric isomaltose are 65 grams.
Its preparation method is: L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, add the 4200ml pure water in the ingredients jar, open Steam Heating to 60 ℃, drop into the oligomeric isomaltose of above-mentioned weight, stirring makes it to dissolve fully, filters, and L-carnitine is dissolved in the pure water, join mix homogeneously in the oligomeric isomaltose solution after the filtration, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 4:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the parts by weight of described L-carnitine are 14 grams, the parts by weight of described oligomeric isomaltose are 55 grams.
Its preparation method is: L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, add the 4200ml pure water in the ingredients jar, open Steam Heating to 70 ℃, drop into the oligomeric isomaltose of above-mentioned weight, stirring makes it to dissolve fully, filters, and L-carnitine is dissolved in the pure water, join mix homogeneously in the oligomeric isomaltose solution after the filtration, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 5:
The compound preparation of fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose, the parts by weight of described L-carnitine are 20 grams, the parts by weight of described oligomeric isomaltose are 90 grams.
Its preparation method is: L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, add the 4500ml pure water in the ingredients jar, open Steam Heating to 80 ℃, drop into the oligomeric isomaltose of above-mentioned weight, stirring makes it to dissolve fully, filters, and L-carnitine is dissolved in the pure water, join mix homogeneously in the oligomeric isomaltose solution after the filtration, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 6:
In the liquid of the foregoing description, also add described citric acid, acesulfame potassium, edible essence, the parts by weight of described citric acid are 5 grams, the parts by weight of described acesulfame potassium are 0.3 gram, the parts by weight of described edible essence are 1 gram, stir to make dissolving evenly, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 7:
In the liquid of the foregoing description, also add described citric acid, acesulfame potassium, edible essence, the weight fraction of described citric acid is 15 grams, the parts by weight of described acesulfame potassium are 2 grams, the parts by weight of described edible essence are 2 grams, stir to make dissolving evenly, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 8:
In the liquid of the foregoing description, also add described citric acid, acesulfame potassium, edible essence, the weight fraction of described citric acid is 6 grams, the parts by weight of described acesulfame potassium are 0.6 gram, the parts by weight of described edible essence are 2, stir to make dissolving evenly, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Embodiment 9:
In the liquid of the foregoing description, also add described citric acid, acesulfame potassium, edible essence, the weight fraction of described citric acid is 20 grams, the parts by weight of described acesulfame potassium are 5 grams, the parts by weight of described edible essence are 4 grams, stir to make dissolving evenly, add the pure water standardize solution to 5000ml, detection level is qualified, sterilization, product is made in fill.Every bottle of 400ml, 1 bottle of every day.
Claims (4)
1. the compound preparation of a fat-reducing, its composition comprises: L-carnitine, oligomeric isomaltose is characterized in that: the ratio of weight and number of described L-carnitine and described oligomeric isomaltose is 5～20: 50～90.
2. the compound preparation of fat-reducing according to claim 1, it is characterized in that: the compound preparation of described fat-reducing contains citric acid, acesulfame potassium, edible essence, the ratio of weight and number of described citric acid is 5～20, the ratio of weight and number of described acesulfame potassium is 0.3～5, and the ratio of weight and number of described edible essence is 1～4.
3. the preparation method of the compound preparation of a fat-reducing, it is characterized in that: L-carnitine, the oligomeric isomaltose of getting above-mentioned parts by weight are standby, the adding parts by weight are 4000～4500 pure water in the ingredients jar, open Steam Heating to 45 ℃～80 ℃, drop into the oligomeric isomaltose of above-mentioned deal, stirring makes it to dissolve fully, filter, L-carnitine is dissolved in the pure water, joins mix homogeneously in the oligomeric isomaltose solution after the filtration, add pure water to parts by weight 5000, detection level is qualified, sterilization, product is made in fill.
4. the preparation method of the compound preparation of fat-reducing according to claim 3, it is characterized in that: in above-mentioned mixed solution, add described citric acid, acesulfame potassium, edible essence, the parts by weight of described citric acid are than 5～20, and the ratio of weight and number of described acesulfame potassium is 0.3～5, and the ratio of weight and number of described edible essence is 1～4, stir, add pure water to parts by weight 5000, detection level is qualified, sterilization, product is made in fill.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510010228 CN1903209A (en) | 2005-07-27 | 2005-07-27 | Weight-reducing compound prepn. and its prepn. method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510010228 CN1903209A (en) | 2005-07-27 | 2005-07-27 | Weight-reducing compound prepn. and its prepn. method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198063A (en) * | 2017-06-13 | 2017-09-26 | 浙江丰岛食品有限公司 | A kind of collagen pawpaw pulp juice drink and preparation method thereof |
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- 2005-07-27 CN CN 200510010228 patent/CN1903209A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198063A (en) * | 2017-06-13 | 2017-09-26 | 浙江丰岛食品有限公司 | A kind of collagen pawpaw pulp juice drink and preparation method thereof |
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Open date: 20070131 |