CN1736270A - Alcohol-dissolving liver-protecting drink and preparation method thereof - Google Patents
Alcohol-dissolving liver-protecting drink and preparation method thereof Download PDFInfo
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- CN1736270A CN1736270A CNA2005100358370A CN200510035837A CN1736270A CN 1736270 A CN1736270 A CN 1736270A CN A2005100358370 A CNA2005100358370 A CN A2005100358370A CN 200510035837 A CN200510035837 A CN 200510035837A CN 1736270 A CN1736270 A CN 1736270A
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Abstract
The invention relates to an alcohol-dissolving liver-protecting drink and preparation method, wherein the constituents include (by weight percent): Chitosan oligosaccharide 0.1-2%, glycyrrhizin 0.1-0.5%, water raffinate of kudzuvine flower 2-10%, water extract of hovenine 1-5% and balancing water.
Description
Technical field
The present invention relates to a kind of alcohol-dissolving liver-protecting drink composition and method of making the same.
Background technology
In daily life, usually run into the situation of drinking beyond one's capacity, drunk back people are uncomfortable feeling such as hot-tempered, the gastric disorder causing nausea of unconsciousness, vexed gas often, and severe patient also can cause alcoholism, weight person's threat to life.The people who drinks for a long time damages liver inevitably.Therefore, since ancient times, people just seeking energy preventing drunkenness, the medicine that relieves the effect of alcohol, protects the liver, Foods or drinks etc., reduce to minimum in the hope of the injury that will drink.
At present existing alcohol-decomposing beverage few in number, but most curative effect is not remarkable, function singleness, mouthfeel are not good, the raw material complexity, and cost is higher, preparation method's complexity, and, add other chemical addition agents such as anticorrisive agent in most beverages, have certain toxic and side effect.
Chinese patent publication number CN1045157C discloses a kind of alcohol-dissolving liver-protecting drink and manufacture method thereof, it is raw material that natural medical flower and leaves of plants are all selected in this invention for use, clinical testing shows that drinking this after drinking invents the made beverage person's state that can improve the drink, and long-term drinking also helps raising capacity for liquor.But the effect of this beverage be forgive blood by clearing away heart-fire, heat conduction is descending, the effect of accelerating alcohol from urine, to discharge and reaching Antialcoholic liver-protecting, therefore it takes effect slower, and beverage itself is less to the decomposition of alcohol, though user's health quite feels comfortable, alcohol alleviates the harm of liver is unsubstantial in vivo.
Summary of the invention
The technical problem to be solved in the present invention is: provide a kind of high efficiency, low cost, manufacturing process simple, need not alcohol-dissolving liver-protecting drink that adds anticorrisive agent and preparation method thereof.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: a kind of alcohol-dissolving liver-protecting drink is provided, and it comprises the component of following quality percentage composition:
Chitosan oligosaccharide 0.1～2%
Glycyrrhizin 0.1～0.5%
FI puerariae water extract 2～10%
Hoveniae semoveniae semen water extract 1～5%
Surplus is a water.
Its component comprises that also the quality percentage composition is 10～20% fruit juice.
Its component comprises that also the quality percentage composition is 1～2% vinegar.
Described fruit juice is one or more fruit juice that press in red grape, apple, orange, the watermelon.
Described chitosan oligosaccharide mean molecule quantity is lower than 5000, the material of this chitosan oligosaccharide is a kind of water-soluble low polymerization degree that to be raw material with the shitosan obtain after degree of depth degraded.
For solving the problems of the technologies described above, another technical scheme of the present invention is: a kind of preparation method of alcohol-dissolving liver-protecting drink may further comprise the steps:
(1) measure the FI puerariae and the hoveniae semoveniae semen of a certain proportion of pulverizing by prescription, add the water of 4～6 times of weight, heating is soaked, and leaves standstill, and filters; And filtrate is concentrated into soup is 4: 1 with the medicinal material ratio, thereby makes FI puerariae and hoveniae semoveniae semen extract;
(2) with fruit through cleaning, peeling, stoning or remove seed is pulverized, and squeezes the juice, and filters, and makes inspissated juice after concentrating;
(3) get the chitosan oligomer and the glycyrrhizin of formula ratio;
(4) FI puerariae and hoveniae semoveniae semen extract, fruit juice, chitosan oligosaccharide and glycyrrhizin and water are made into alcohol-dissolving liver-protecting drink;
Wherein, the quality percentage composition of each material component:
Chitosan oligosaccharide 0.1～2%
Glycyrrhizin 0.1～0.5%
FI puerariae water extract 2～10%
Hoveniae semoveniae semen water extract 1～5%
Inspissated juice 10～20%
Surplus is a water.
Heating and immersion are meant and are heated to 75～85 ℃ in the described step (1), soak under this temperature 60～90 minutes.
The invention has the beneficial effects as follows: contain chitosan oligomer, glycyrrhizin, FI puerariae water extract, hoveniae semoveniae semen water extract in the alcohol-dissolving liver-protecting drink of the present invention, so this beverage not only has the wine of curing the wound heating, the greasy acid regurgitation of vomitting, discharging fresh blood stool, the relieving restlessness of quenching the thirst, moisturizing viscera, sharp stool and urine, control drunk polydipsia, vomiting, etc. effect, and it contains the composition that decomposes acetaldehyde, ethanol, therefore can alleviate the injury of alcohol in itself, and it is fast to relieve the effect of alcohol to liver and health.In addition, not needing to add other chemical preservatives in this alcohol-dissolving liver-protecting drink preserves.
And, also containing fruit juice and vinegar in the beverage of the present invention, its local flavor is preferable, and the similar fruit juice of taste both had been fit to drink after drinking before the wine, also was fit to drink at ordinary times.
Alcohol-dissolving liver-protecting drink prescription of the present invention is simple, and preparation were established is simple, and cost is lower, helps suitability for industrialized production.
The specific embodiment
The invention provides a kind of beverage of Antialcoholic liver-protecting, preceding, the neutralization of drinking of being suitable for drinking is drunk after drinking.Drink before drinking and in drinking can prevent drunk, improve anti-capacity for liquor, drink the time of sobering up of can shortening after drinking, reduce the injury of alcohol human organ.Each composition weight percentage composition of this alcohol-dissolving liver-protecting drink is as follows:
Chitosan oligosaccharide 0.1～2%
Glycyrrhizin 0.1～0.5%
FI puerariae water extract 2～10%
Hoveniae semoveniae semen water extract 1～5%
Inspissated juice 10～20%
Vinegar 1～2%
Surplus is a water.
The preparation of this alcohol-dissolving liver-protecting drink may further comprise the steps:
(1) measures the FI puerariae and the hoveniae semoveniae semen of a certain proportion of pulverizing by prescription, add 4～6 times water, be heated to 75～85 ℃, under this temperature, soaked 60～90 minutes, leave standstill, filter; And filtrate is concentrated into soup is 4: 1 with the medicinal material ratio, thereby makes FI puerariae and hoveniae semoveniae semen extract;
(2) with one or more fresh fruits in red grape, apple, orange, the watermelon through cleaning, peeling, stoning or remove seed is pulverized, and squeezes the juice, and filters, and makes inspissated juice after concentrating.
(3) get the chitosan oligomer and the glycyrrhizin of formula ratio;
(4) vinegar with FI puerariae and hoveniae semoveniae semen extract, fruit juice, chitosan oligosaccharide and glycyrrhizin, formula ratio mixes with water, homogeneous, and sterilization filling is alcohol-dissolving liver-protecting drink.
The fruit of aforementioned used squeezing juice is one or more in red grape, apple, orange, the watermelon, fruit juice and be preferably red grape juice and watermelon juice.
Chitosan oligosaccharide is a kind of chitosan oligomer, it is the material of a kind of water-soluble low polymerization degree that to be raw material with the shitosan obtain after degree of depth degraded, chitosan oligosaccharide is consistent with the molecular configuration of shitosan basically, only be because the minimizing of molecular weight, the reduction of the degree of polymerization but makes chitosan oligosaccharide have to be different from the excellent function of shitosan fully.But the metabolic process of chitosan oligosaccharide acceleration of alcohol in human body.Alcohol enters in the body, is decomposed by liver, becomes acetaldehyde, causes after drinking and has a headache, feels sick, and brings infringement to liver.Chitosan oligosaccharide can improve liver function and promote detoxication, acetaldehyde is decomposed rapidly, become the nonhazardous material, remove ethanol and acetaldehyde hepatocellular coup injury, shorten the alcohol and the metabolite time of staying in vivo thereof, reduced the absorption of internal organs to these materials, reduced the alcohol concentration in the unit interval inner blood, it is slow that drunk existing picture is occurred, drunk degree alleviates, obviously shorten and sober up the time, accelerate ataxic after drinking recovery, reduce the concentration of alcohol in the serum.And chitosan oligosaccharide can be used as anticorrisive agent, and the alcohol-dissolving liver-protecting drink that has therefore added chitosan oligosaccharide does not need to add other chemical preservatives.
Glycyrrhizin (being glycyrrhizic acid) is contained a kind of pentacyclic triterpene saponin in the root of Radix Glycyrrhizae and the rhizome.As most important active component in the Radix Glycyrrhizae, glycyrrhizin has functions such as detoxifcation, anti-carious tooth, anti-inflammatory.Glycyrrhizin is absorbed the back, is broken down into enoxolone and Radix Glycyrrhizae aldehydic acid in liver by body, and the latter can combine with the noxious material that contains hydroxyl or carboxyl and generate nontoxic compound and excrete the function of realization detoxifcation.
FI puerariae is slightly cold, and it is sweet, flat to distinguish the flavor of, and little hardship is gone into sufficient Yangming Channel, activating spleen by relieving alcoholism, the wine that cures the wound heating, do not feel like eating, the greasy acid regurgitation of vomitting, spitting blood, discharging fresh blood stool.
Hoveniae semoveniae semen, it is sweet, flat to distinguish the flavor of, and goes into the heart, spleen two warps, the relieving restlessness of quenching the thirst, moisturizing viscera, sharp stool and urine is controlled drunk polydipsia, vomiting, difficulty in urination and defecation.
Contain organic acids such as tartaric acid in the fruit juice, for example contain tartaric acid in the grape, contain malic acid in the apple, contain citric acid in the orange, these acid can generate Ester with the ethanol synthesis in the wine, thereby reach the purpose of relieving the effect of alcohol.Also be rich in the multiple vitamin that can relieve the effect of alcohol in addition in the fruit, for example vitamin C and B family vitamin.Li Shizhen (1518-1593 A.D.) is just pointed out in Compendium of Material Medica, watermelon " Li Xiaoshui controls bloody flux, relieving alcoholism for treatment larynx numbness, the wide middle therapeutic method to keep the adverse qi flowing downward ".
Acetate in the vinegar can generate ethyl acetate with alcohol reaction, reduce alcohol concentration in the body, also contain nutritional labeling and flavor components such as each seed amino acid, organic acid, carbohydrate, vitamin, pure and mild ester in addition in the vinegar, have unique color, can improve the local flavor of beverage of the present invention.
Alcohol-dissolving liver-protecting drink of the present invention not only has the wine of curing the wound heating, the greasy acid regurgitation of vomitting, discharging fresh blood stool, the relieving restlessness of quenching the thirst, moisturizing viscera, sharp stool and urine is controlled drunk polydipsia, vomiting, etc. effect, and, it contains the composition that decomposes acetaldehyde, ethanol, therefore can alleviate the injury of alcohol to liver and health in itself, and it is fast to relieve the effect of alcohol.In addition, do not need to add other chemical preservatives in this alcohol-dissolving liver-protecting drink and preserve, its local flavor is preferable, and the similar fruit juice of taste both had been fit to drink after drinking before the wine, also was fit to drink at ordinary times.
Alcohol-dissolving liver-protecting drink prescription of the present invention is simple, and preparation were established is simple, and cost is lower, helps suitability for industrialized production.
Following table 1 is made six example products in a manner described with six prescriptions, and component content is its mass percentage concentration in the aqueous solution in each prescription:
Six kinds of formula for a product of table 1
| Composition | Prescription 1 | Prescription 2 | Prescription 3 | Prescription 4 | Prescription 5 | Prescription 6 |
| Chitosan oligosaccharide glycyrrhizin FI puerariae water extract hoveniae semoveniae semen water extract fruit juice vinegar | 0.1％ 0.5％ 10％ 5％ 10％ 2.0％ | 0.5％ 0.4％ 7.0％ 4.0％ 12％ 1.8％ | 0.8％ 0.25％ 5.0％ 2.5％ 14％ 1.6％ | 1.0％ 0.3％ 6.0％ 3.0％ 16％ 1.5％ | 1.5％ 0.2％ 4.0％ 2.0％ 18％ 1.2％ | 2.0％ 0.1％ 2.0％ 1.0％ 20％ 1.0％ |
Select 90 examples drunk person in various degree to be divided into 6 groups and respectively above-mentioned 6 example products are carried out clinical observation,, take and recover normal in about 20 minutes of this beverage for slight drunk symptoms such as instability of gait; For vomiting, the drunk symptom of insobriety even depth, take this product after, various malaise symptoms obviously alleviate or eliminate in 30 minutes, can comfortablely fall asleep, and can avoid fully or alleviate after drinking have a stomachache, the pantothenic acid symptom.Drink before the wine and can delay the drunk time, increase drinking amount, drink after drinking to reduce and feel bad degree after drinking, shorten and sober up the time.
Claims (10)
1, a kind of alcohol-dissolving liver-protecting drink, it comprises the component of following quality percentage composition:
Chitosan oligosaccharide 0.1～2%
Glycyrrhizin 0.1～0.5%
FI puerariae water extract 2～10%
Hoveniae semoveniae semen water extract 1～5%
Surplus is a water.
2, alcohol-dissolving liver-protecting drink as claimed in claim 1 is characterized in that: its component comprises that also the quality percentage composition is 10～20% inspissated juices.
3, alcohol-dissolving liver-protecting drink as claimed in claim 1 is characterized in that: its component comprises that also the quality percentage composition is 1～2% vinegar.
4, alcohol-dissolving liver-protecting drink as claimed in claim 2 is characterized in that: described inspissated juice be one or more fresh fruits in red grape, apple, orange, the watermelon through cleaning, peeling, stoning or remove seed is pulverized, and squeezes the juice, and filters the fruit juice after concentrating.
5, alcohol-dissolving liver-protecting drink as claimed in claim 1 is characterized in that: described chitosan oligosaccharide average molecular mass is lower than 5000, the material of this chitosan oligosaccharide is a kind of water-soluble low polymerization degree that to be raw material with the shitosan obtain after degree of depth degraded.
6, a kind of preparation method of alcohol-dissolving liver-protecting drink may further comprise the steps:
(1) measure the FI puerariae and the hoveniae semoveniae semen of a certain proportion of pulverizing by prescription, add the water of 4～6 times of weight, heating is soaked, and leaves standstill, and filters; And filtrate is concentrated into soup is 4: 1 with the medicinal material ratio, thereby makes FI puerariae and hoveniae semoveniae semen extract;
(2) with fruit through cleaning, peeling, stoning or remove seed is pulverized, and squeezes the juice, and filters, and obtains inspissated juice after concentrating;
(3) get the chitosan oligosaccharide and the glycyrrhizin of formula ratio;
(4) FI puerariae and hoveniae semoveniae semen extract, inspissated juice, chitosan oligosaccharide and glycyrrhizin are mixed with water, homogeneous, sterilization filling is alcohol-dissolving liver-protecting drink;
Wherein, the quality percentage composition of each material component:
Chitosan oligosaccharide 0.1～2%
Glycyrrhizin 0.1～0.5%
FI puerariae water extract 2～10%
Hoveniae semoveniae semen water extract 1～5%
Fruit juice 10～20%
Surplus is a water.
7, the preparation method of alcohol-dissolving liver-protecting drink as claimed in claim 6 is characterized in that: the described fruit of making inspissated juice is one or more in red grape, apple, orange, the watermelon.
8, the preparation method of alcohol-dissolving liver-protecting drink as claimed in claim 6 is characterized in that: heating and immersion are meant and are heated to 75～85 ℃ in the described step (1), soak under this temperature 60～90 minutes.
9, the preparation method of alcohol-dissolving liver-protecting drink as claimed in claim 6, it is characterized in that: the material of described chitosan oligosaccharide is a kind of water-soluble low polymerization degree that to be raw material with the shitosan obtain after degree of depth degraded, described glycyrrhizin are contained a kind of pentacyclic triterpene saponins in the root of Radix Glycyrrhizae and the rhizome.
10, the preparation method of alcohol-dissolving liver-protecting drink as claimed in claim 6 is characterized in that: comprise also in the described step (4) that adding quality percentage amounts is 1～2% vinegar.
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| CN1736270A true CN1736270A (en) | 2006-02-22 |
| CN100539877C CN100539877C (en) | 2009-09-16 |
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| CN102160613A (en) * | 2010-02-22 | 2011-08-24 | 贝军 | Biological product for strengthening stomach, protecting liver and preserving health and preparation method thereof |
| CN102499341A (en) * | 2011-12-31 | 2012-06-20 | 苏州先阔生物科技有限公司 | Anti-hangover product and application of composition of xylo-oligosaccharide and Citrus fruit extract in anti-hangover product |
| CN101518330B (en) * | 2009-02-22 | 2012-09-19 | 曹斌 | Drink before wine and method for making same |
| CN102697122A (en) * | 2012-06-15 | 2012-10-03 | 南京农业大学 | Purple sweet potato vinegar healthcare beverage |
| CN102697129A (en) * | 2012-05-22 | 2012-10-03 | 广东健生堂保健品有限公司 | Semen hoveniae plant beverage and preparation method thereof |
| CN102715396A (en) * | 2012-07-17 | 2012-10-10 | 山东鲁健生物医药科技有限公司 | Special diet formula containing chitosan oligosaccharide and oligopeptide for hepatopaths |
| CN101653283B (en) * | 2009-09-10 | 2012-10-17 | 张树文 | Chitosan oligosaccharide drinking water |
| CN103237465A (en) * | 2010-12-27 | 2013-08-07 | 顺天大学校产学协力团 | Drink composition for hangover relief, containing cucumber vinegar |
| WO2014177989A2 (en) | 2013-04-29 | 2014-11-06 | Chigurupati Technologies Private Limited | Reduced toxicity in alcoholic beverages |
| CN104286842A (en) * | 2014-09-12 | 2015-01-21 | 刘益君 | Compound composition tablet with functions of dispelling effects of alcohol and protecting liver |
| CN105326087A (en) * | 2014-08-12 | 2016-02-17 | 佛山市万绿素电子科技有限公司 | Electronic cigarette tobacco tar with functions of alleviating hangover and protecting liver |
| CN105639339A (en) * | 2015-12-29 | 2016-06-08 | 珠海市金隆生物科技有限公司 | Fatigue-resistance and immunity-enhancement chitosan oligosaccharide beverage and preparation method thereof |
| CN105661403A (en) * | 2016-02-22 | 2016-06-15 | 宁百成 | Hovenia acerba and red date food and producing method thereof |
| CN105707598A (en) * | 2016-02-16 | 2016-06-29 | 云南博尚生物技术有限公司 | Plant drink for dispelling alcohol effects and preparation method thereof |
| CN105815647A (en) * | 2016-05-26 | 2016-08-03 | 江苏耐雀生物工程技术有限公司 | Solid drink capable of dispelling effect of alcohol and protecting liver and preparation method and application thereof |
| CN109007213A (en) * | 2018-07-10 | 2018-12-18 | 青岛高新区尚达医药研究所 | A kind of relieving alcoholism and protecting liver sugar cube and preparation method thereof |
| US10456359B2 (en) | 2015-06-19 | 2019-10-29 | Harsha Chigurupati | Synergistic beverage composition |
| CN112715809A (en) * | 2021-01-05 | 2021-04-30 | 晋江市宏品优创贸易有限公司 | Fruit juice for dispelling effects of alcohol and protecting liver |
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2005
- 2005-07-05 CN CN200510035837.0A patent/CN100539877C/en not_active Expired - Fee Related
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| CN101518330B (en) * | 2009-02-22 | 2012-09-19 | 曹斌 | Drink before wine and method for making same |
| CN101653283B (en) * | 2009-09-10 | 2012-10-17 | 张树文 | Chitosan oligosaccharide drinking water |
| CN102160613A (en) * | 2010-02-22 | 2011-08-24 | 贝军 | Biological product for strengthening stomach, protecting liver and preserving health and preparation method thereof |
| CN103237465A (en) * | 2010-12-27 | 2013-08-07 | 顺天大学校产学协力团 | Drink composition for hangover relief, containing cucumber vinegar |
| CN102499341A (en) * | 2011-12-31 | 2012-06-20 | 苏州先阔生物科技有限公司 | Anti-hangover product and application of composition of xylo-oligosaccharide and Citrus fruit extract in anti-hangover product |
| CN102697129A (en) * | 2012-05-22 | 2012-10-03 | 广东健生堂保健品有限公司 | Semen hoveniae plant beverage and preparation method thereof |
| CN102697129B (en) * | 2012-05-22 | 2014-03-12 | 广东健生堂保健品有限公司 | Semen hoveniae plant beverage and preparation method thereof |
| CN102697122A (en) * | 2012-06-15 | 2012-10-03 | 南京农业大学 | Purple sweet potato vinegar healthcare beverage |
| CN102715396A (en) * | 2012-07-17 | 2012-10-10 | 山东鲁健生物医药科技有限公司 | Special diet formula containing chitosan oligosaccharide and oligopeptide for hepatopaths |
| CN102715396B (en) * | 2012-07-17 | 2013-06-19 | 山东鲁健生物医药科技有限公司 | Special diet formula containing chitosan oligosaccharide and oligopeptide for hepatopaths |
| WO2014177989A2 (en) | 2013-04-29 | 2014-11-06 | Chigurupati Technologies Private Limited | Reduced toxicity in alcoholic beverages |
| CN105326087A (en) * | 2014-08-12 | 2016-02-17 | 佛山市万绿素电子科技有限公司 | Electronic cigarette tobacco tar with functions of alleviating hangover and protecting liver |
| CN104286842A (en) * | 2014-09-12 | 2015-01-21 | 刘益君 | Compound composition tablet with functions of dispelling effects of alcohol and protecting liver |
| US10456359B2 (en) | 2015-06-19 | 2019-10-29 | Harsha Chigurupati | Synergistic beverage composition |
| CN105639339A (en) * | 2015-12-29 | 2016-06-08 | 珠海市金隆生物科技有限公司 | Fatigue-resistance and immunity-enhancement chitosan oligosaccharide beverage and preparation method thereof |
| CN105707598A (en) * | 2016-02-16 | 2016-06-29 | 云南博尚生物技术有限公司 | Plant drink for dispelling alcohol effects and preparation method thereof |
| CN105707598B (en) * | 2016-02-16 | 2019-01-04 | 云南良旺生物科技有限公司 | A kind of Antialcoholic plant drink and preparation method thereof |
| CN105661403A (en) * | 2016-02-22 | 2016-06-15 | 宁百成 | Hovenia acerba and red date food and producing method thereof |
| CN105815647A (en) * | 2016-05-26 | 2016-08-03 | 江苏耐雀生物工程技术有限公司 | Solid drink capable of dispelling effect of alcohol and protecting liver and preparation method and application thereof |
| CN109007213A (en) * | 2018-07-10 | 2018-12-18 | 青岛高新区尚达医药研究所 | A kind of relieving alcoholism and protecting liver sugar cube and preparation method thereof |
| CN112715809A (en) * | 2021-01-05 | 2021-04-30 | 晋江市宏品优创贸易有限公司 | Fruit juice for dispelling effects of alcohol and protecting liver |
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Application publication date: 20060222 Assignee: Upper reaches Limited by Share Ltd Assignor: Huang Hengshen Contract record no.: 2010440000326 Denomination of invention: Drink for dispelling effects of liquor and protecting liver and its preparation method Granted publication date: 20090916 License type: Exclusive License Record date: 20100330 |
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