CN1895557A - Chinese-medicinal herb for treating hypertension, high-blood-fat and hyperglycosemia - Google Patents
Chinese-medicinal herb for treating hypertension, high-blood-fat and hyperglycosemia Download PDFInfo
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Abstract
A Chinese medicine for treating hypertension, hyperlipemia and hyperglycemia is prepared from 22 Chinese-medicinal materials including chrysanthemum flower, astragalus root, red sage root, haw, etc.
Description
Technical field
The present invention relates to a kind of herbal mediciment compositions for the treatment of disturbance of blood circulation diseases such as hypertension, hyperlipidemia, hyperglycemia.
Background technology
Disturbance of blood circulation diseases such as clinical treatment hypertension, hyperlipidemia, hyperglycemia mainly are to adopt medicines such as nitroglycerin, SUXIAO JIUXIN WAN, urokinase, streptokinase at present, although that these medicines have is rapid-action, effect is remarkable, stronger toxic and side effects such as having a headache often appears in the patient, feeling of fullness in the head even cerebral hemorrhage; Though the Chinese herbal medicine of employing decoction effective component extracting is also arranged, often has shortcomings such as difficulty absorbs, effective ingredient is destroyed.
Goal of the invention
The object of the invention is to provide a kind of herbal mediciment compositions for the treatment of disturbance of blood circulation diseases such as hypertension, hyperlipidemia, hyperglycemia, to overcome the drawback that prior art exists.
Summary of the invention
For realizing the object of the invention, the present invention is formulated by the raw material components of following portions by weight ratio:
Flos Chrysanthemi 10～25 Semen Cassiaes 10～25 Radixs Astragali 10～60
Radix Salviae Miltiorrhizae 5～40 Fructus Crataegis 10～25 Fructus Lycii 5～30
Ramulus Uncariae Cum Uncis 10～45 Spica Prunellaes 10～25 Radix Notoginseng 3～40
Radix Polygoni Multiflori 10～50 Rhizoma Polygonatis 10～50 Haematitums 10～30
Rhizoma Chuanxiong 3～30 Radix Achyranthis Bidentataes 6～25 Concha Ostreaes 15～30
Rhizoma Gastrodiae 3～40 Endothelium Corneum Gigeriae Galli 3～25 Poria 10～25
Radix Scutellariae 3～20 Cortexs Eucommiae 10～25 Herba Epimedii 10～25
Caulis Spatholobi 10～30.
Described each composition weight umber ratio is preferably:
Flos Chrysanthemi 20 Semen Cassiaes 20 Radixs Astragali 40
Radix Salviae Miltiorrhizae 30 Fructus Crataegis 20 Fructus Lycii 20
Ramulus Uncariae Cum Uncis 30 Spica Prunellaes 20 Radix Notoginseng 30
Radix Polygoni Multiflori 40 Rhizoma Polygonatis 40 Haematitums 20
Rhizoma Chuanxiong 20 Radix Achyranthis Bidentataes 20 Concha Ostreaes 30
Rhizoma Gastrodiae 30 Endothelium Corneum Gigeriae Galli 20 Poria 20
Radix Scutellariae 15 Cortexs Eucommiae 20 Herba Epimedii 20
Caulis Spatholobi 30.
Preparation method of the present invention is: after getting each component by above-mentioned prescription, clean, dry, pulverize, incapsulate behind 100～120 mesh sieves excessively, or make other dosage form.
The effect of each component of the present invention is respectively:
Flos Chrysanthemi: the sweet in the mouth suffering has effects such as wind and heat dispersing, blood pressure lowering, suppressing the hyperactive liver to relieve the wind syndrome.
Semen Cassiae: sweet in the mouth cold in nature, go into liver, kidney, large intestine channel.Have loosening bowel to relieve constipation, blood fat reducing makes eye bright, liver heat removing and eyesight improving, and effects such as diuretic relieving constipation can be used for treating constipation and hyperlipidemia, hypertension.
The Radix Astragali: sweet in the mouth warm in nature has invigorating QI to consolidate the body surface resistance, yang invigorating diuretic effect.Have the heart tonifying hypotensive effect, myocardial cell is lacked sugared hypoxic damage protective effect, myocardial cell is beaten slow down, and increases myocardial contraction.
Radix Salviae Miltiorrhizae: bitter in the mouth cold in nature has blood circulation promoting and blood stasis dispelling, the effect of removing heat from blood eliminating carbuncle nourishing blood to tranquillize the mind.Can be used for coronary artery dilator, increase coronary flow, decreased heart rate suppresses myocardial contraction, and microcirculation improvement increases blood capillary tension force, improves the ability of tissue picked-up oxygen from microcirculation, promotes the utilization of body to oxygen.Can also reduce platelet aggregation, anticoagulation is arranged, can improve hemorheological property, reduce blood viscosity, and then microcirculation improvement.
Fructus Crataegi: sour in the mouth and be with sweetly, slightly warm in nature is gone into spleen, stomach warp, and having disappears lets out circulation of qi promoting, the wide diaphragm that is good for the stomach, activating blood circulation to dissipate blood stasis, effect such as anticancer.Energy vessel softening, cholesterol reducing content, appetite promoting and the spleen strengthening, promotion bile secretion.But prevention of brain angiopathy, hypertension, gastrointestinal disease etc.Hypertension, hyperlipemia, coronary heart disease etc. all there is certain curative effect.
Fructus Lycii: sweet in the mouth is flat, returns liver, kidney channel, has the effect of the kidney invigorating nourishing the liver, nourishing blood for improving eyesight, nourishing the lung to arrest cough, spleen-benefiting mind-tranquilizing.Fructus Lycii has facilitation to hemopoietic function, can make leukocytosis, and has and effect such as protect the liver, bring high blood pressure down.
Ramulus Uncariae Cum Uncis: sweet in the mouth cold in nature, return liver, pericardium channel.Has the endogenous wind stopping relieving convulsion, the effect of heat clearing away suppressing the hyperactive liver.Ramulus Uncariae Cum Uncis has tangible hypotensive effect, can suppress vasomotor center, directly expands peripheral vessel, and suppresses the release of neuroganglion tip mediator, and hypotensive effect is gentle lasting.
Spica Prunellae: bitter in the mouth cold in nature, suffering, have clearing away liver-fire, Disperse hepatic depression, the effect of ending ophthalmalgia have persistent hypotensive effect.
Radix Notoginseng: sweet, the little hardship of nature and flavor, tepor, GUIXIN, liver, spleen channel, effects such as antiinflammatory, promoting blood circulation to remove blood stasis, hemostasis, detumescence, pain relieving are arranged, have blood vessel dilating, slow down heart rate, bring high blood pressure down, coronary blood flow increasing, antianginal, improve the pharmacological action of cardiovascular system state of an illness symptom, but microcirculation improvement, prevention and treatment heart and brain tissues ischemia.
Radix Polygoni Multiflori: slightly warm in nature, bitter but sweet flavor is puckery, effects such as only pained, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, benefiting qi and nourishing blood are arranged, and have pharmacological actions such as blood fat reducing, arteriosclerosis, strong nerve, promotion erythrocyte growth promoter, the growth cycle that prolongs cultured cell in vitro and heart tonifying.Relevant experimentation shows that the Radix Polygoni Multiflori contains chrysophanic acid, can promote intestinal movement, and prevention or minimizing lipid are in intestinal absorption, thereby rate and blood-lipid decreased.
Rhizoma Polygonati: nature and flavor are sweet flat, return spleen, lung, kidney channel.Effect such as there are nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, Zhichuan to disappear to cough.Have moist cardiopulmonary, invigorating the spleen and replenishing QI, remove rheumatism, settling five organs, bone and muscle strengthening, end cold and heat, replenishing essence marrow, the effect such as fill blood of reducing internal heat.Can bring high blood pressure down, increase coronary flow, also have the effect of blood fat reducing and blood glucose.
Haematitum: bitter in the mouth cold in nature, the GUIXIN Liver Channel has the effect of suppressing the hyperactive liver and subsiding YANG, sending down the abnormal ascending QI wind, cooling blood for hemostasis.Be mainly used in diseases such as headache due to the excessive rising of liver-YANG, dizzy, tinnitus, can promote the new life of erythrocyte and hemoglobin, and have sedation.
Rhizoma Chuanxiong: acrid in the mouth is warm in nature, and the effect of blood-activating and qi-promoting, wind-expelling pain-stopping is arranged, and has effects such as blood pressure lowering, coronary artery dilator, coronary blood flow increasing, reduction myocardial oxygen consumption, increase brain and LBF amount, reduction peripheral vascular resistance.
Radix Achyranthis Bidentatae: the flat sweet in the mouth of property has effects such as promoting blood circulation to remove blood stasis, conducting blood to flow downwards, invigorating the liver and kidney, bone and muscle strengthening.Have stronger protein synthesis facilitation, hypotensive effect is arranged, and can suppress effects such as heart and expansion peripheral vessels.
Concha Ostreae: salty in the mouth cold in nature, return the Liver and kidney warp.Have suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving, the astringent or styptic treatment for spontaneous sweating effect of convergence.
Rhizoma Gastrodiae: the flat sweet in the mouth of property has effects such as suppressing the hyperactive liver to relieve the wind syndrome, only dizzy, the QI invigorating nourishing the liver of arresting convulsion, relieving fainting.Dizzy and the control cerebral thrombosiss of the headache that excessive rising of liver-YANG is caused etc. are powerful greatly.Have calmness, hypotensive effect, but decreased heart rate improves hypoxia-bearing capability, and myocardial ischemia is had protective effect, can expand peripheral blood vessel, and the heart of increasing, cerebral blood flow are arranged, and reduces effects such as cerebral vascular resistance.
Endothelium Corneum Gigeriae Galli: the flat sweet in the mouth of property has effects such as activating the spleen helps digestion.
Poria: the flat sweet in the mouth of property, light.GUIXIN, lung, spleen, kidney channel.Have eliminating dampness by diuresis, spleen invigorating, the effect of allaying excitement.And have blood sugar lowering, calmness, etc. effect.
Radix Scutellariae: the nature and flavor bitter cold, return lung, stomach, gallbladder, large intestine channel.Have effects such as purte the white, heat-clearing and toxic substances removing, blood pressure lowering calmness.
The Cortex Eucommiae: Gan Wen returns liver, kidney channel, and invigorating the liver and kidney, strong muscles and bones are arranged, and blood pressure reduction effect is best in the world natural antihypertensive drugs.
Herba Epimedii: property acrid-sweet flavor, temperature, go into kidney channel, kidney invigorating and YANG supporting, beneficial vital essence, hard muscles and bones are arranged, mend effects such as waist knee joint, heart tonifying power, expelling wind and removing dampness.The modern pharmacology experimentation shows that Herba Epimedii can increase the cardiovascular and cerebrovascular vessel blood flow, promotes hemopoietic function, and also expansible vascular smooth muscle and the cerebral blood flow increasing amount reduces cerebral vascular resistance is protected cerebral ischemia.
Caulis Spatholobi: bitter in the mouth warm in nature, little sweet, return Liver Channel.Has blood circulation promoting and enriching, effects such as dispelling wind and removing obstruction in the collateral.
In the present invention, but Flos Chrysanthemi and Semen Cassiae, the blood pressure lowering of Ramulus Uncariae Cum Uncis compatibility suppressing the hyperactive liver; But with the blood pressure lowering of Radix Astragali compatibility heart tonifying; But with the anticoagulant of Radix Salviae Miltiorrhizae compatibility, to fall blood sticking; But with Fructus Crataegi compatibility vessel softening.Ramulus Uncariae Cum Uncis, Spica Prunellae, Semen Cassiae, Radix Scutellariae compatibility have that suppressing the hyperactive liver blood pressure lowering, endogenous wind stopping relieving convulsion, clearing away liver-fire make eye bright, the analgesic effect.Radix Salviae Miltiorrhizae and Radix Notoginseng, Fructus Crataegi, Rhizoma Chuanxiong compatibility have the effect of antiinflammatory, anticoagulant hemostasis, alleviating pain and detumescence, thereby reduce that blood is sticking, the generation of vessel softening, microcirculation improvement, prevention cardiovascular and cerebrovascular disease.But Fructus Crataegi and the blood fat reducing of Radix Polygoni Multiflori compatibility, arteriosclerosis, nourshing blood and promoting blood circulation, strong nerve.Rhizoma Polygonati is joined the effect that Poria, Endothelium corneum have spleen invigorating, lung moistening, QI invigorating to allay excitement, but blood fat reducing, calmness.Haematitum, Concha Ostreae, Rhizoma Gastrodiae have the effect of town's liver YANG hyperactivity suppressing, sending down the abnormal ascending QI wind, can treat headache, dizziness that hypertension, hyperlipidemia, high blood viscosity cause, and the control cerebral thrombosis improves cardiac and cerebral blood-supply, reduces cerebral vascular resistance.But Herba Epimedii, Radix Achyranthis Bidentatae, the Cortex Eucommiae, Fructus Lycii compatibility kidney invigorating and YANG supporting, beneficial vital essence, hard muscles and bones, mend waist knee joint, heart tonifying power, the effects such as falling wet, conducting blood to flow downwards of dispeling the wind.Using medicines of both cold and hot natures simultaneously of the present invention, Gan Xin matches, removing fire from the liver and the gas that do not injure one's stomach complements each other.
Among the present invention, be that monarch is with reducing pressure and sugar with Flos Chrysanthemi, Semen Cassiae, the Radix Astragali, Radix Salviae Miltiorrhizae, Fructus Crataegi, Radix Notoginseng with effects such as heat clearing away suppressing the hyperactive liver, blood circulation promoting and blood stasis dispelling, refreshment eyesight improvings; Minister is with the effect of Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Spica Prunellae, Haematitum, Concha Ostreae, Radix Scutellariae Ke Da town liver YANG hyperactivity suppressing, endogenous wind stopping relieving convulsion, to prevent the generation of cardiovascular and cerebrovascular disease; But assistant is with the Radix Polygoni Multiflori, Endothelium corneum, Caulis Spatholobi, the Rhizoma Chuanxiong of liver and kidney tonifying, bone and muscle strengthening, supplementing the brain benefit marrow, the dehumidifying effect of dispeling the wind.All medicine compatibilities amount to the effect of blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver to relieve the wind syndrome, bone and muscle strengthening, reducing pressure and sugar blood fat reducing.
Clinical drug of the present invention uses the result to show that remarkable characteristic of following several respects and effect are arranged:
1. have suppressing the hyperactive liver nourishing the liver, endogenous wind stopping relieving convulsion, end dizzy relieving fainting effect, with blood pressure lowering, blood fat reducing, blood sugar lowering improves cerebral blood supply.
2. have blood circulation promoting and blood stasis dispelling, heart tonifying diuresis, but blood pressure lowering, viscosity reduction, coronary dilating, coronary blood flow increasing, decreased heart rate suppresses myocardial contraction, microcirculation improvement.
3. have tonic irritability, strong muscles and bones, supplementing the brain benefit marrow, nourishing blood for improving eyesight effect, promote hemopoietic function, make leukocytosis, vessel softening, strong nerve increases brain and body blood flow, reduces peripheral vascular resistance and reaches that the clever order of brain is bright, limbs are nimble.
4. have nourishing blood for improving eyesight, nourishing the lung to arrest cough, spleen-invigorating and sedative action, can protect the liver blood pressure lowering, regulating gastointestinal, so that the five internal organs Ankang, spirit and QI cleaning.
5. prove through long-term clinical observation and treatment, determined curative effect of the present invention, produce effects is fast, and stable, the patient suffering is few, and expense is low, and more the no any sequela in back does not have any anaphylaxis and toxic and side effects, has a extensive future.
The present invention selects hypertension, hyperlipidemia, hyperglycemia case 300 examples during year March October to 2006 calendar year 2001 to be the clinical observation object, by statistics, and effective and 289 examples that produce a desired effect, clinical cure 213 examples, clinical effective rate is 96.3%, clinical cure rate 71%, invalid 11 examples.
The present invention is as follows at some model cases of clinical practice:
Case 1: model, the woman, 71 years old, the Shijiazhuang City people suffered from 35 years history of hypertension, once takes Western medicine depressor throughout the year, and begin to take the present invention in November, 2005, takes drug withdrawal behind three first quarter moons continuously, and blood pressure stabilization is in normal range, and body and mind is strong, and is hale and hearty.
Case 2: Wei, the woman, 74 years old, the Shijiazhuang City people once suffered from 28 years hypertension medical histories, and with hyperlipidemia, hyperglycemia more than ten years, 2001 begin to take the present invention, after 6 months by checking blood pressure, blood fat, blood glucose, the sticking normal level that reaches of blood.
Case 3: Chen, the woman, 70 years old, Jingxing, Hebei province mining area family members, former blood pressure is often taken Western medicine depressor at 100～180mmHg, take half a year of the present invention after, at present blood pressure maintains 85～140mmHg, and has cut out all antihypertensive drugs now.
Case 4: Liu, the man, 65 years old, the Shijiazhuang City people, suffering from hypertension has 5 years, and by taking the present invention two months, existing blood pressure has recovered normal.
Case 5: week certain, the woman, 56 years old, the Shijiazhuang City people suffered from hypertension before 3 years, took the present invention after two months, existing its blood pressure returns to normally.
Case 6: the marquis, the woman, 56 years old, hypertension, hyperlipidemia, hyperglycemia, high blood viscosity were once suffered from by Shijiazhuang retired employees, take half a year of the present invention after, now recovered normal.
The invention will be further described below in conjunction with specific embodiment:
Embodiment 1: dry after 20g Flos Chrysanthemi, 20g Semen Cassiae, the 40g Radix Astragali, 30g Radix Salviae Miltiorrhizae, 20g Fructus Crataegi, 20g Fructus Lycii, 30g Ramulus Uncariae Cum Uncis, 20g Spica Prunellae, 30g Radix Notoginseng, 40g Radix Polygoni Multiflori, 40g Rhizoma Polygonati, 20g Haematitum, 20g Rhizoma Chuanxiong, 20g Radix Achyranthis Bidentatae, 30g Concha Ostreae, 30g Rhizoma Gastrodiae, 20g Endothelium Corneum Gigeriae Galli, 20g Poria, 15g Radix Scutellariae, the 20g Cortex Eucommiae, 20g Herba Epimedii and 30g Caulis Spatholobi are cleaned, pulverize the back and cross 100～120 mesh sieves, sterilization gets final product with 0.5g dosage No. 0 oral capsule of packing into then.
Following other embodiment difference from Example 1 sees the following form:
Unit: (g)
Instructions of taking of the present invention: take night and morning, each 1～2, warm water delivery service.2～4 months one courses of treatment, generally take 1～2 course of treatment.
Claims (4)
1. herbal mediciment for the treatment of hypertension, hyperlipidemia, hyperglycemia is characterized in that it is made by the raw material of following weight parts:
Flos Chrysanthemi 10～25 Semen Cassiaes 10～25 Radixs Astragali 10～60
Radix Salviae Miltiorrhizae 5～40 Fructus Crataegis 10～25 Fructus Lycii 5～30
Ramulus Uncariae Cum Uncis 10～45 Spica Prunellaes 10～25 Radix Notoginseng 3～40
Radix Polygoni Multiflori 10～50 Rhizoma Polygonatis 10～50 Haematitums 10～30
Rhizoma Chuanxiong 3～30 Radix Achyranthis Bidentataes 6～25 Concha Ostreaes 15～30
Rhizoma Gastrodiae 3～40 Endothelium Corneum Gigeriae Galli 3～25 Poria 10～25
Radix Scutellariae 3～20 Cortexs Eucommiae 10～25 Herba Epimedii 10～25
Caulis Spatholobi 10～30.
2. according to the described treatment hypertension of claim 1, hyperlipidemia, hyperglycemia herbal mediciment, it is characterized in that described each composition weight umber ratio is:
Flos Chrysanthemi 20 Semen Cassiaes 20 Radixs Astragali 40
Radix Salviae Miltiorrhizae 30 Fructus Crataegis 20 Fructus Lycii 20
Ramulus Uncariae Cum Uncis 30 Spica Prunellaes 20 Radix Notoginseng 30
Radix Polygoni Multiflori 40 Rhizoma Polygonatis 40 Haematitums 20
Rhizoma Chuanxiong 20 Radix Achyranthis Bidentataes 20 Concha Ostreaes 30
Rhizoma Gastrodiae 30 Endothelium Corneum Gigeriae Galli 20 Poria 20
Radix Scutellariae 15 Cortexs Eucommiae 20 Herba Epimedii 20
Caulis Spatholobi 30.
3. according to claim 1 or 2 described treatment hypertension, hyperlipidemia, hyperglycemia herbal mediciment, it is characterized in that described medicament is a said dosage form in any pharmaceutics.
4. treatment hypertension according to claim 3, hyperlipidemia, hyperglycemia herbal mediciment is characterized in that described dosage form is a capsule formulation.
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