CN1894407A - 特异性结合生物活性生长素释放肽的核酸 - Google Patents

特异性结合生物活性生长素释放肽的核酸 Download PDF

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Publication number
CN1894407A
CN1894407A CNA2004800377977A CN200480037797A CN1894407A CN 1894407 A CN1894407 A CN 1894407A CN A2004800377977 A CNA2004800377977 A CN A2004800377977A CN 200480037797 A CN200480037797 A CN 200480037797A CN 1894407 A CN1894407 A CN 1894407A
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Prior art keywords
nucleic acid
ghrelin
bioactive
detection means
purposes
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CNA2004800377977A
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English (en)
Chinese (zh)
Inventor
S·克鲁斯曼
S·赫尔姆灵
D·乌尔博格
C·玛施
K·布驰尼尔
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TME Pharma AG
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Noxxon Pharma AG
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Publication of CN1894407A publication Critical patent/CN1894407A/zh
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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CNA2004800377977A 2003-11-10 2004-11-10 特异性结合生物活性生长素释放肽的核酸 Pending CN1894407A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025743.0 2003-11-10
EP03025743 2003-11-10

Publications (1)

Publication Number Publication Date
CN1894407A true CN1894407A (zh) 2007-01-10

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ID=34610046

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CNA2004800377977A Pending CN1894407A (zh) 2003-11-10 2004-11-10 特异性结合生物活性生长素释放肽的核酸

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US (2) US20070031840A1 (cg-RX-API-DMAC7.html)
EP (1) EP1682662A1 (cg-RX-API-DMAC7.html)
JP (1) JP4823067B2 (cg-RX-API-DMAC7.html)
KR (1) KR20060125743A (cg-RX-API-DMAC7.html)
CN (1) CN1894407A (cg-RX-API-DMAC7.html)
AP (1) AP2006003618A0 (cg-RX-API-DMAC7.html)
AU (1) AU2004291656A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0415872A (cg-RX-API-DMAC7.html)
CA (1) CA2544805A1 (cg-RX-API-DMAC7.html)
CR (1) CR8388A (cg-RX-API-DMAC7.html)
EA (1) EA009376B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP066559A (cg-RX-API-DMAC7.html)
IL (1) IL175443A0 (cg-RX-API-DMAC7.html)
MA (1) MA28153A1 (cg-RX-API-DMAC7.html)
NO (1) NO20062663L (cg-RX-API-DMAC7.html)
OA (1) OA13282A (cg-RX-API-DMAC7.html)
TN (1) TNSN06132A1 (cg-RX-API-DMAC7.html)
WO (1) WO2005049828A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200603435B (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003251681A1 (en) * 2002-08-01 2004-02-23 Noxxon Pharma Ag Ghrelin binding nucleic acids
EP2290071B1 (en) * 2004-05-28 2014-12-31 Asuragen, Inc. Methods and compositions involving microRNA
AU2005333165B2 (en) 2004-11-12 2012-07-19 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
WO2008073922A2 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Functions and targets of let-7 micro rnas
UY29460A1 (es) 2005-04-08 2006-11-30 Noxxon Pharma Ag Acidos nucleicos de union a ghrelin
CA2663962A1 (en) * 2006-09-19 2008-03-27 Asuragen, Inc. Mir-15, mir-26, mir-31,mir-145, mir-147, mir-188, mir-215, mir-216, mir-331, mmu-mir-292-3p regulated genes and pathways as targets for therapeutic intervention
AU2007299828C1 (en) * 2006-09-19 2014-07-17 Interpace Diagnostics, Llc MicroRNAs differentially expressed in pancreatic diseases and uses thereof
CN101622349A (zh) * 2006-12-08 2010-01-06 奥斯瑞根公司 作为治疗性干预靶标的miR-21调节的基因和途径
AU2007333107A1 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. miR-21 regulated genes and pathways as targets for therapeutic intervention
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
US20090232893A1 (en) * 2007-05-22 2009-09-17 Bader Andreas G miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
US20090131354A1 (en) * 2007-05-22 2009-05-21 Bader Andreas G miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
CN101801419A (zh) * 2007-06-08 2010-08-11 米尔纳疗法公司 作为治疗干预的靶标的miR-34调控的基因和路径
EP2198050A1 (en) 2007-09-14 2010-06-23 Asuragen, INC. Micrornas differentially expressed in cervical cancer and uses thereof
US20090186015A1 (en) * 2007-10-18 2009-07-23 Latham Gary J Micrornas differentially expressed in lung diseases and uses thereof
US8071562B2 (en) * 2007-12-01 2011-12-06 Mirna Therapeutics, Inc. MiR-124 regulated genes and pathways as targets for therapeutic intervention
WO2009086156A2 (en) * 2007-12-21 2009-07-09 Asuragen, Inc. Mir-10 regulated genes and pathways as targets for therapeutic intervention
WO2009100430A2 (en) * 2008-02-08 2009-08-13 Asuragen, Inc miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
WO2009111643A2 (en) * 2008-03-06 2009-09-11 Asuragen, Inc. Microrna markers for recurrence of colorectal cancer
EP2271757A2 (en) * 2008-03-26 2011-01-12 Asuragen, INC. Compositions and methods related to mir-16 and therapy of prostate cancer
EP2990487A1 (en) 2008-05-08 2016-03-02 Asuragen, INC. Compositions and methods related to mirna modulation of neovascularization or angiogenesis
US20100179213A1 (en) * 2008-11-11 2010-07-15 Mirna Therapeutics, Inc. Methods and Compositions Involving miRNAs In Cancer Stem Cells
US20110105389A1 (en) 2009-10-30 2011-05-05 Hoveyda Hamid R Macrocyclic Ghrelin Receptor Antagonists and Inverse Agonists and Methods of Using the Same
EP2663640B1 (en) * 2011-01-10 2020-11-04 APTARION biotech AG Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease

Family Cites Families (9)

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US5614395A (en) * 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
AU663053B2 (en) * 1990-06-11 1995-09-28 Gilead Sciences, Inc. Nucleic acid ligands
WO1996034879A1 (en) * 1995-05-03 1996-11-07 Whitehead Institute For Biomedical Research Identification of enantiomeric ligands
US5780221A (en) * 1995-05-03 1998-07-14 Whitehead Institute For Biomedical Research Identification of enantiomeric ligands
US20030211967A1 (en) * 2001-05-07 2003-11-13 Bryant Henry Uhlman Method for selectively inhibiting ghrelin action
WO2001087335A2 (en) * 2000-05-17 2001-11-22 Eli Lilly And Company Method for selectively inhibiting ghrelin action
CA2411667A1 (en) * 2000-05-30 2001-12-06 Merck & Co. Inc. Ghrelin analogs
AU2003251681A1 (en) * 2002-08-01 2004-02-23 Noxxon Pharma Ag Ghrelin binding nucleic acids
UY29460A1 (es) * 2005-04-08 2006-11-30 Noxxon Pharma Ag Acidos nucleicos de union a ghrelin

Also Published As

Publication number Publication date
MA28153A1 (fr) 2006-09-01
US20100261291A1 (en) 2010-10-14
AP2006003618A0 (en) 2006-06-30
CR8388A (es) 2006-10-17
EA009376B1 (ru) 2007-12-28
EP1682662A1 (en) 2006-07-26
US20070031840A1 (en) 2007-02-08
AU2004291656A1 (en) 2005-06-02
ZA200603435B (en) 2007-06-27
IL175443A0 (en) 2006-09-05
ECSP066559A (cg-RX-API-DMAC7.html) 2006-11-24
NO20062663L (no) 2006-08-09
TNSN06132A1 (fr) 2007-11-15
CA2544805A1 (en) 2005-06-02
OA13282A (en) 2007-01-31
WO2005049828A1 (en) 2005-06-02
EA200600735A1 (ru) 2006-10-27
JP4823067B2 (ja) 2011-11-24
BRPI0415872A (pt) 2007-01-09
KR20060125743A (ko) 2006-12-06
JP2007513608A (ja) 2007-05-31

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