CN1882342A - Chk1抑制剂在控制细胞增殖中的应用 - Google Patents

Chk1抑制剂在控制细胞增殖中的应用 Download PDF

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Publication number
CN1882342A
CN1882342A CNA200480033853XA CN200480033853A CN1882342A CN 1882342 A CN1882342 A CN 1882342A CN A200480033853X A CNA200480033853X A CN A200480033853XA CN 200480033853 A CN200480033853 A CN 200480033853A CN 1882342 A CN1882342 A CN 1882342A
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substituted
unsubstituted
alkyl
heterocyclyl
aryl
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CNA200480033853XA
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Chinese (zh)
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D·克拉克
K·S·基甘
S·彼得森
M·魏纳
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Eli Lilly and Co
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Icos Corp
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
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CNA200480033853XA 2003-09-17 2004-09-17 Chk1抑制剂在控制细胞增殖中的应用 Pending CN1882342A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50392503P 2003-09-17 2003-09-17
US60/503,925 2003-09-17

Publications (1)

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CN1882342A true CN1882342A (zh) 2006-12-20

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CNA200480033853XA Pending CN1882342A (zh) 2003-09-17 2004-09-17 Chk1抑制剂在控制细胞增殖中的应用

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US (1) US20070185013A1 (cg-RX-API-DMAC7.html)
EP (1) EP1667684A1 (cg-RX-API-DMAC7.html)
JP (1) JP2007519609A (cg-RX-API-DMAC7.html)
KR (1) KR20070064414A (cg-RX-API-DMAC7.html)
CN (1) CN1882342A (cg-RX-API-DMAC7.html)
AU (1) AU2004274013A1 (cg-RX-API-DMAC7.html)
CA (1) CA2539320A1 (cg-RX-API-DMAC7.html)
IL (1) IL174334A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA06003110A (cg-RX-API-DMAC7.html)
NO (1) NO20061475L (cg-RX-API-DMAC7.html)
RU (1) RU2006112548A (cg-RX-API-DMAC7.html)
WO (1) WO2005027907A1 (cg-RX-API-DMAC7.html)

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US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP2009523149A (ja) * 2006-01-12 2009-06-18 ノバルティス アクチエンゲゼルシャフト ｍＴＯＲ阻害剤および抗葉酸化合物の組み合わせ
JP2010505962A (ja) 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
NZ575394A (en) * 2006-10-20 2012-01-12 Icos Corp Compositions of chk1 inhibitors and cyclodextrin
EP2086644A2 (en) * 2006-11-17 2009-08-12 Schering Corporation Combination of an inhibitor of dna polymerase-alpha and an inhibitor of a checkpoint kinase for proliferative disorders
CA2674075C (en) * 2006-12-29 2012-10-30 Charles P. Theuer Antifolate agent combinations in the treatment of cancer
WO2009099601A2 (en) * 2008-02-04 2009-08-13 Dana-Farber Cancer Institute, Inc. Chk1 suppresses a caspase-2 apoptotic response to dna damage that bypasses p53, bcl-2 and caspase-3
EP3563862B1 (en) * 2009-03-20 2021-05-05 The General Hospital Corporation d/b/a Massachusetts General Hospital D-arg-2'6'-dimethyltyrosine-lys-phe-nh2 for use in the prevention of secondary complications of burn injuries
KR101676062B1 (ko) * 2009-04-11 2016-11-14 어레이 바이오파마 인크. Ｄｎａ 손상제를 강화시키기 위한 체크포인트 키나제 1 억제제
US8481557B2 (en) 2009-04-11 2013-07-09 Array Biopharma Inc. Method of treatment using checkpoint kinase 1 inhibitors
CN108721284A (zh) 2010-11-16 2018-11-02 阵列生物制药公司 检测点激酶1抑制剂和wee1激酶抑制剂的组合
WO2015036463A1 (en) * 2013-09-12 2015-03-19 Merz Pharma Gmbh & Co. Kgaa Topical application of vinca alkaloids for the treatment of actinic keratosis
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CN105198790B (zh) * 2015-04-20 2018-02-16 范国煌 促进双阴性t细胞体外增殖的四环化合物

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IL174334A0 (en) 2006-08-01
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EP1667684A1 (en) 2006-06-14
MXPA06003110A (es) 2006-06-20
JP2007519609A (ja) 2007-07-19
WO2005027907A1 (en) 2005-03-31
NO20061475L (no) 2006-06-13
RU2006112548A (ru) 2007-10-27
CA2539320A1 (en) 2005-03-31
AU2004274013A1 (en) 2005-03-31

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