CN1857274A - Medicine composition for treating valval and/or vaginal infection - Google Patents
Medicine composition for treating valval and/or vaginal infection Download PDFInfo
- Publication number
- CN1857274A CN1857274A CN 200610072089 CN200610072089A CN1857274A CN 1857274 A CN1857274 A CN 1857274A CN 200610072089 CN200610072089 CN 200610072089 CN 200610072089 A CN200610072089 A CN 200610072089A CN 1857274 A CN1857274 A CN 1857274A
- Authority
- CN
- China
- Prior art keywords
- metronidazole
- promestriene
- pharmaceutical composition
- daily dose
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010046914 Vaginal infection Diseases 0.000 title claims abstract description 14
- 239000003814 drug Substances 0.000 title abstract description 20
- 239000000203 mixture Substances 0.000 title abstract description 13
- 229940079593 drug Drugs 0.000 title description 9
- KRNYOVHEKOBTEF-YUMQZZPRSA-N Val-Val Chemical compound CC(C)[C@H](N)C(=O)N[C@@H](C(C)C)C(O)=O KRNYOVHEKOBTEF-YUMQZZPRSA-N 0.000 title 1
- 108010021889 valylvaline Proteins 0.000 title 1
- 229960000282 metronidazole Drugs 0.000 claims abstract description 31
- 229960002152 chlorhexidine acetate Drugs 0.000 claims abstract description 29
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 claims abstract description 29
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229960004765 promestriene Drugs 0.000 claims abstract description 25
- IUWKNLFTJBHTSD-AANPDWTMSA-N promestriene Chemical compound C1C[C@]2(C)[C@@H](OC)CC[C@H]2[C@@H]2CCC3=CC(OCCC)=CC=C3[C@H]21 IUWKNLFTJBHTSD-AANPDWTMSA-N 0.000 claims abstract description 25
- 239000002775 capsule Substances 0.000 claims abstract description 10
- 239000000829 suppository Substances 0.000 claims abstract description 5
- 239000003826 tablet Substances 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 25
- 239000008194 pharmaceutical composition Substances 0.000 claims description 20
- 239000002552 dosage form Substances 0.000 claims description 5
- 238000005406 washing Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 abstract description 15
- 210000001215 vagina Anatomy 0.000 abstract description 13
- 208000002003 vulvitis Diseases 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 26
- 230000000694 effects Effects 0.000 description 23
- -1 metronidazole compound Chemical class 0.000 description 15
- 229960003260 chlorhexidine Drugs 0.000 description 14
- 241000700159 Rattus Species 0.000 description 10
- 238000011160 research Methods 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 9
- 241000283973 Oryctolagus cuniculus Species 0.000 description 8
- 239000007901 soft capsule Substances 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 7
- 230000003203 everyday effect Effects 0.000 description 7
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- 230000002354 daily effect Effects 0.000 description 6
- 238000011084 recovery Methods 0.000 description 6
- 239000003871 white petrolatum Substances 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 230000002159 abnormal effect Effects 0.000 description 5
- 239000000470 constituent Substances 0.000 description 5
- 235000014113 dietary fatty acids Nutrition 0.000 description 5
- 230000005284 excitation Effects 0.000 description 5
- 229930195729 fatty acid Natural products 0.000 description 5
- 239000000194 fatty acid Substances 0.000 description 5
- 150000004665 fatty acids Chemical class 0.000 description 5
- 239000012188 paraffin wax Substances 0.000 description 5
- 206010003693 Atrophic vulvovaginitis Diseases 0.000 description 4
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 206010020565 Hyperaemia Diseases 0.000 description 4
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000002147 killing effect Effects 0.000 description 4
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 description 4
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 239000013642 negative control Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 241000191992 Peptostreptococcus Species 0.000 description 2
- 208000019802 Sexually transmitted disease Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000013872 defecation Effects 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 2
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 239000007903 gelatin capsule Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 239000013641 positive control Substances 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 description 1
- 206010003504 Aspiration Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000606125 Bacteroides Species 0.000 description 1
- 241000606123 Bacteroides thetaiotaomicron Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013183 Dislocation of vertebra Diseases 0.000 description 1
- 206010015719 Exsanguination Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000207201 Gardnerella vaginalis Species 0.000 description 1
- 206010061977 Genital infection female Diseases 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 description 1
- 241000588653 Neisseria Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 241000700584 Simplexvirus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000031737 Tissue Adhesions Diseases 0.000 description 1
- 208000007074 Trichomonas Vaginitis Diseases 0.000 description 1
- 208000025206 Trichomonas vaginitis urogenital infection Diseases 0.000 description 1
- 201000008100 Vaginitis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000002547 anomalous effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960004022 clotrimazole Drugs 0.000 description 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000001076 estrogenic effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 231100001252 long-term toxicity Toxicity 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 229960002509 miconazole Drugs 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 231100000255 pathogenic effect Toxicity 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229960005078 sorbitan sesquioleate Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Lot number | Storage time (moon) | The investigation project | ||||||
Outward appearance | The content character | Catabolite | The molten change time limit (branch) | Indicate content (%) | ||||
Promestriene | Chlorhexidine acetate | Metronidazole | ||||||
040901 | 0 | Oval | Oily liquids | Do not have | 12 | 98.56 | 110.08 | 96.11 |
1 | Oval | Oily liquids | Do not have | 11 | 98.32 | 109.02 | 96.37 | |
2 | Oval | Oily liquids | Do not have | 13 | 97.96 | 108.33 | 96.27 | |
3 | Oval | Oily liquids | Do not have | 12 | 97.68 | 107.46 | 95.69 | |
6 | Oval | Oily liquids | Do not have | 11 | 97.46 | 107.32 | 95.68 | |
040902 | 0 | Oval | Oily liquids | Do not have | 13 | 98.79 | 108.29 | 96.78 |
1 | Oval | Oily liquids | Do not have | 11 | 98.67 | 107.96 | 96.78 | |
2 | Oval | Oily liquids | Do not have | 12 | 98.56 | 107.48 | 96.68 | |
3 | Oval | Oily liquids | Do not have | 11 | 98.46 | 107.17 | 96.47 |
6 | Oval | Oily liquids | Do not have | 12 | 97.69 | 106.97 | 95.96 | |
040903 | 0 | Oval | Oily liquids | Do not have | 13 | 97.86 | 104.56 | 98.33 |
1 | Oval | Oily liquids | Do not have | 12 | 97.77 | 104.27 | 97.96 | |
2 | Oval | Oily liquids | Do not have | 10 | 97.65 | 103.87 | 97.83 | |
3 | Oval | Oily liquids | Do not have | 11 | 97.54 | 103.75 | 97.81 | |
6 | Oval | Oily liquids | Do not have | 13 | 97.43 | 103.6 | 96.98 |
The example number | Recovery from illness | Effectively | Invalid | Total effective rate | |||||
The example number | Cure rate | The example number | Effective percentage | The example number | Inefficiency | ||||
Trichomonal vaginitis | Test group | 20 | 17 | 85% | 2 | 10% | 1 | 5% | 95% |
Matched group | 20 | 12 | 60% | 4 | 20% | 4 | 20% | 80% |
The example number | Recovery from illness | Effectively | Invalid | Total effective rate | |||||
The example number | Cure rate | The example number | Effective percentage | The example number | Inefficiency | ||||
Colpitis mycotica | Test group | 20 | 19 | 95% | 1 | 5% | 0 | 0% | 100% |
Matched group | 20 | 11 | 55% | 6 | 30% | 3 | 15% | 85% |
The example number | Recovery from illness | Effectively | Invalid | Total effective rate | |||||
The example number | Cure rate | The example number | Effective percentage | The example number | Inefficiency | ||||
Nonspecific vaginitis | Test group | 20 | 17 | 85% | 2 | 10 | 1 | 5% | 95% |
Matched group | 20 | 13 | 65% | 4 | 20 | 1 | 5% | 95% |
The example number | Recovery from illness | Effectively | Invalid | Total effective rate | |||||
The example number | Cure rate | The example number | Effective percentage | The example number | Inefficiency | ||||
Senile vaginitis | Test group | 20 | 15 | 75% | 4 | 20% | 1 | 5% | 95% |
Matched group | 20 | 14 | 70% | 4 | 20% | 1 | 5% | 95% |
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100720898A CN100408041C (en) | 2006-04-10 | 2006-04-10 | Medicine composition for treating valval and/or vaginal infection |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100720898A CN100408041C (en) | 2006-04-10 | 2006-04-10 | Medicine composition for treating valval and/or vaginal infection |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1857274A true CN1857274A (en) | 2006-11-08 |
CN100408041C CN100408041C (en) | 2008-08-06 |
Family
ID=37296262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2006100720898A Expired - Fee Related CN100408041C (en) | 2006-04-10 | 2006-04-10 | Medicine composition for treating valval and/or vaginal infection |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN100408041C (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA014292B1 (en) * | 2008-02-18 | 2010-10-29 | Открытое Акционерное Общество "Нижегородский Химико-Фармацевтический Завод" (Оао "Нижфарм") | Medico-prophylactic agent having antibacterial and spermicidal activity |
CN104490871A (en) * | 2014-11-24 | 2015-04-08 | 江苏远恒药业有限公司 | Compound chlorhexidine acetate suppository, and preparation method thereof |
CN106074435A (en) * | 2016-06-30 | 2016-11-09 | 浙江安宝药业有限公司 | Rubber of promestriene vagina soft gelatin capsule and preparation method thereof |
CN111407821A (en) * | 2020-05-06 | 2020-07-14 | 福建深林农业科技有限责任公司 | Pueraria-containing anti-inflammation itching-relieving maintenance and repair washing product |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1600315A (en) * | 2003-09-22 | 2005-03-30 | 陈云芳 | Soft capsule combination of Cloquinate/Promestriene in use for vagina |
-
2006
- 2006-04-10 CN CNB2006100720898A patent/CN100408041C/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA014292B1 (en) * | 2008-02-18 | 2010-10-29 | Открытое Акционерное Общество "Нижегородский Химико-Фармацевтический Завод" (Оао "Нижфарм") | Medico-prophylactic agent having antibacterial and spermicidal activity |
CN104490871A (en) * | 2014-11-24 | 2015-04-08 | 江苏远恒药业有限公司 | Compound chlorhexidine acetate suppository, and preparation method thereof |
CN106074435A (en) * | 2016-06-30 | 2016-11-09 | 浙江安宝药业有限公司 | Rubber of promestriene vagina soft gelatin capsule and preparation method thereof |
CN111407821A (en) * | 2020-05-06 | 2020-07-14 | 福建深林农业科技有限责任公司 | Pueraria-containing anti-inflammation itching-relieving maintenance and repair washing product |
Also Published As
Publication number | Publication date |
---|---|
CN100408041C (en) | 2008-08-06 |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: BEIJING LANEVA PHARMACEUTICAL CO.,LTD. Assignor: Yang Jun Contract fulfillment period: 2009.9.16 to 2014.9.15 Contract record no.: 2009990001226 Denomination of invention: Medicine composition for treating valval and/or vaginal infection Granted publication date: 20080806 License type: Exclusive license Record date: 20091104 |
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LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2009.9.16 TO 2014.9.15; CHANGE OF CONTRACT Name of requester: BEIJING LANGYI PHARMACEUTICAL CO., LTD. Effective date: 20091104 |
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ASS | Succession or assignment of patent right |
Owner name: BEIJING LANEVA PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: YANG JUN Effective date: 20150319 |
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C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 100020 CHAOYANG, BEIJING TO: 100024 CHAOYANG, BEIJING |
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TR01 | Transfer of patent right |
Effective date of registration: 20150319 Address after: 100024 No. 559 Shuangqiao Village, Guan Zhuang Town, Beijing, Chaoyang District Patentee after: BEIJING LANEVA PHARMACEUTICAL CO.,LTD. Address before: 100020, No. 903, building 1302, nine district, Chaoyang District, Beijing, Jinsong Patentee before: Yang Jun |
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CP03 | Change of name, title or address | ||
CP03 | Change of name, title or address |
Address after: 101300 No.9 Mintai Road, Beiwu Town, Shunyi District, Beijing Patentee after: Beijing Jincheng Taier Pharmaceutical Co.,Ltd. Address before: 100024 No. 559, shuangqiaoli, Guanzhuang Township, Chaoyang District, Beijing Patentee before: BEIJING LANEVA PHARMACEUTICAL Co.,Ltd. |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080806 |
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CF01 | Termination of patent right due to non-payment of annual fee |