CN1843453A - Traditional Chinese medicinal composition for treating barrenness and its preparing process - Google Patents
Traditional Chinese medicinal composition for treating barrenness and its preparing process Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating women's barrenness, wherein the raw materials include tortoise shell, deglued antler sheet, Hippocampus japonicus, anemarrhena rhizome, baikal skullcap root, epimeddium, matrimony vine, cornus officinalis, leeches, pseudostellaria root, Chinese angelica root, rhubarb horsetails and spatholobus stem.
Description
Technical field
The invention belongs to pharmaceutical field, relate to a kind of Chinese medicine composition, be specifically related to be used for the treatment of the Chinese medicine composition of woman's acyesis, relate to the preparation method of said composition simultaneously
Background technology
Have the report of closing, 15% the living the region between the heart and the diaphragm ability of married couple is arranged approximately, wherein female acyesis accounts for 2/3.Cause infertile reason a lot, pathological changes such as hypophysis cerebri, ovary, uterus, fallopian tube all can cause infertile, and gynecological inflammation also is to cause infertile key factor.Modern doctor trained in Western medicine can rely on several different methods to measure the cause of disease, but produces little effect in treatment, and the expense costliness, and therefore, how sickness rate and infertile crowd in the face of rising gradually prevent and treat infertility, is the common problem of paying close attention to of numerous patients and medical personnel.Common infertile reason has several: the bad implantation that can influence germ cell of the region between the heart and the diaphragm is sent out in the uterus; Genitals's inflammation, wherein salpingemphraxis accounts for infertility about 50%; Dilatation and curettage reaches all easy damaged genitals of nosocomial infection post-abortion puerperal after the operation on pelvis, cause secondary infection; The menopathy that ovarian dysfunction, neuroendocrine disturbance cause, as menoxenia, dysmenorrhea, amenorrhea, dysfunctional uterine bleedings etc. all can cause infertile; Current research finds that socio-psychological factors also is major reason some well-known reason such as the smokings that cause female acyesis, drinks, and improper nourishing, obesity, air environmental pollutions etc. also can breed to the women and bring very big influence.
Motherland's medical science is familiar with except that geneogenous physiological defect the cause of disease of infertility, and often duty is asthenia of renal qi, insufficiency of vital energy and blood, and depression of liver-QI, phlegm-damp obstructions etc. so that Chong and Ren channel disorder can not be fertilized into pregnant.Chinese herbal treatment energy reinforcing the kidney and supporting YANG, liver-smoothing, qi-regulating, heat-clearing and toxic substances removing, drying dampness to eliminate phlegm, regulating menstruation and activating blood makes to dash to appoint and leads to, and mechanism of qi is in harmonious proportion, and the essence of photographing easily is impregnated, and the traditional Chinese medical science be can yet be regarded as and treated the desirable therapy of infertility.
The western medical treatment means mainly are the water flowing arts and use ovulation stimulants.Yet the water flowing art not only can not successfully be dredged for the serious patient of fallopian tube, also very likely because repeatedly water flowing art damage fallopian tube, the fallopian tube function is reduced and increases the weight of the state of an illness.The use of hormones promoting ovulation drug simultaneously has a strong impact on the balance of female incretion, has increased the weight of the dyshormonia that just exists originally on the contrary, can't fundamentally cure infertility.
The Chinese herbal treatment infertility is historical of long standing and well established and evident in efficacy, Chinese medicine had not been interrupted over more than 2000 years the treatment of infertility, Huangdi's Internal Classics proposes the important insight of " governor vessel is for sick; infertilitas feminis ", and the Tang Dynasty king of medicine Sun Simiao then is listed in first first of " preemergency a thousand pieces of gold prescription " volume to " asking son ".
At present, the infertile curative effect of Chinese herbal treatment has obtained the concern of world medical circle, draws the elite of traditional Chinese traditional treatment female barrenness, ginseng with doctor trained in Western medicine to infertility, the good medicine of seeking the treatment infertilitas feminis is digested in the accurate analysis of pathology, is just becoming the common objective of Chinese and Western medical circles.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition, be used for the infertility due to diagnosis and treatment follicular dysplasia or the luteal insufficiency, plan to implement test-tube baby (IVF-ET) treatment and follicular dysplasia person, recurrent spontaneous abortion, high year infertility person.
Chinese medicine composition of the present invention is according to kidney tonifying, essence replenishing, and benefiting QI for activating blood circulation is held up the policy of educating the follicle healthy development, and with the not dry the moon of QI invigorating, the crystalline substance of not hindering positive medicine delivery and power-assist kidney tonifying, essence replenishing of invigorating blood circulation is gone into menses (hypothalamic pituitary ovarium axis arteries and veins) running.Adopt three flavor principal agents to be the in love product of flesh and blood: Carapax et Plastrum Testudinis is salty-cold goes into liver, kidney channel, YIN nourishing replenishing essence; The salty temperature of Cornu Cervi tablet is gone into liver, kidney channel, the QI invigorating YANG invigorating, and strong essence is invigorated blood circulation, and property is directly gentle than deer; A small amount of sweet temperature of Hippocampus is gone into liver, kidney channel, mending with the Carapax et Plastrum Testudinis YIN YANG interdislocation syndrome, and helps the vital essence transpiration.Get the Fructus Corni that sour and astringent tepor goes into liver, kidney channel in the adjuvant and hold back Liver and kidney, beneficial vital essence is stained with a moon water deficiency, controls skin ulcer on the face; Sweet fragrant tepor is gone into the Herba Epimedii of liver, kidney channel, and the kidney invigorating and essence nourishing is cultivated to dash and appointed treating YIN within YANG; Sweet Fructus Lycii of putting down into spleen, liver, kidney, lung meridian, liver and kidney tonifying; And put down into liver, urinary bladder channel the Hirudo that clots absorbing stimulates the menstrual flow with a small amount of salty hardship; Sweet flat tepor is gone into the Caulis Spatholobi of liver, kidney channel, enriches blood and invigorates blood circulation, and relaxes through collateral dredging, controls women's impairment caused by overstrain QI and blood, the cold womb conception failture; Close sweetness and bitterness and be slightly cold into spleen, lung meridian, the QI invigorating nourishing the stomach, the Radix Pseudostellariae of heat clearing away YIN nourishing, the not dry the moon of QI invigorating helps gentle blood circulation promoting medicine operation internal organs QI of channels and collaterals blood to help menses in order to the crystalline substance of all invigorating the liver and kidney.Rhizoma Anemarrhenae bitter cold is gone into lung, stomach, kidney channel, nourishing YIN and clearing away heat in the side; Huang-the Siberian cocklebur bitter cold clears away heart-fire, the heat of lung, liver, gallbladder, large intestine is with the removing summer-heat dysphoria with smothery sensation, and this two medicine can go the hot of all tepor medicines in the side; Partly measure the sweet arduous temperature of Radix Angelicae Sinensis and go into the heart, liver, spleen channel promoting the circulation of blood and blood, double assistant makes it to imitate.
Chinese medicine composition of the present invention is through clinical confirmation, in high year of 35 years old to 40 years old diagnosis and treatment age infertility, result from the recurrent spontaneous abortion disease of follicular dysplasia and luteal insufficiency or test-tube baby (1VFET) failure or prepared to carry out (IVF-ET) in high year and solve in a large amount of cases of pregnant person of going because of the follicle function is not good, better effects is arranged really.Patient's ovarian function obviously improves in the treatment, and follicle is better grown, transparent leucorrhoea grow in quantity, basal body temperature two-phase rising program and time all increase, menorrhagia changes cerise, and follicle stimulating hormone (FSH) level that raises in the blood is descended, and poor endometrium is progressive additive also.Thereby make the patient can normal pregnancy or (IVF-ET) be easy to success, the kidney-reinforcing drug of being got, though YIN YANG interdislocation syndrome is mended, relatively nourishing YIN has the replenishing YIN and removing heat medicine auxiliary again, patient is declined or low estrogen receptor level is risen, increase hormone effect (comprising tissue and blood vessel etc.); Also impel Marjoram Extract with light clear drugs for nourishing qi and activating blood simultaneously, blood flow increases, and improves the microenvironment based on ovary, and blood circulation promoting medicine Hirudo amount is little, but the reduction blood viscosity is arranged, and the kidney invigorating effect of class Herba Epimedii is arranged.So medicine of the present invention also is that to regulate with the hypothalamic pituitary ovarium axis be the drug effect that the life network at center rises.
Each raw material of Chinese medicine that medicine of the present invention adopted has following feature:
The Rhizoma Anemarrhenae: be the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bge..Spring, Qiu Erji excavate, and remove fibrous root and silt, dry.Nature and flavor hardship, sweet, cold.Return lung, stomach, kidney channel.Have clearing away heat-fire, promote the production of body fluid and moisturize.Be used for fever caused by exogenous pathogenic factors, the hyperpyrexia excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, the dryness of the intestine constipation.
Carapax et Plastrum Testudinis: be carapace and the sternite of Testudinidae animal Testudinis Chinemys reevesii (Gray).All can catch the whole year, with autumn, two seasons of winter be many, kill after the seizure, or scald deadly with boiling water, strip carapace and sternite, remove residual meat, dry.Nature and flavor are salty, sweet, are slightly cold.Return liver, kidney, heart channel.Has nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.Be used for deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and the muscles and bones flaccidity is soft, and it is forgetful to have a guilty conscience.
Cornu Cervi tablet: the old angle ossified for animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus cuts into lamellar through processing.Nature and flavor are salty, temperature.1. " herbal classic ": " temperature." 2. " not Lu ": " and salty in the mouth, tepor, nontoxic ".Go into liver, kidney channel.1. " must join book on Chinese herbal medicine ": " few sun of starting with, meridian of Foot-SHAO YIN blood system." 2. " key medicine is divided agent ": " and go into kidney channel, double go into the heart, liver two through ".Has promoting the circulation of blood, detumescence, kidney tonifying.The treatment of ulcer toxic swelling, blood stasis is had a pain, asthenia internal injury, lumbar vertebrae pain.Join Radix Angelicae Sinensis from ancient times and enrich blood to nourish blood, Liver and kidney is saying of benefit also.
Hippocampus: be the dry body of Syngnathidae animal strain line Hippocampus Hippocampus kelloggi Jordan et Snyder, HIPPOCAMPUS Hippocampus histrix Kaup, big Hippocampus Hippocampus kuda Bleeder, hippocampus trimaculatus Leacs Hippocampus trimaculatus Leach or little Hippocampus (HAIQU) Hippocampusjaponicaus Kaup.Summer, Qiu Erji catch labor, clean, and dry; Or remove epithelium and internal organs, dry.Nature and flavor are sweet, temperature.Return liver, kidney channel.Has warming the kidney to invigorate YANG, mass dissipating and swelling eliminating.Be used for sexual impotence, the enuresis is suffered from a deficiency of the kidney and is made Chuan ， WEIJIA and gather injury from falling down; External treatment carbuncle furuncle.
Radix Scutellariae: be the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.Spring, Qiu Erji excavate, and remove fibrous root and silt, hit rough bark after the solarization, dry.The nature and flavor hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Herba Epimedii: be the dry aerial parts of Berberidaceae plant Herba Epimedii Epimedium brevicornum Maxim., arrow leaf Herba Epimedii Epimediumsagittatum (Sieb.et Zucc.) Maxim., pubescence Herba Epimedii Epimediumpubescens Maxim., Epimedium wushanense Epimedium wushanense T.S.Ying or Herba Epimedii Epimedium koreanum Nakai.Tap when stem and leaf is luxuriant between summer, autumn, remove thick stalk and impurity, dry or dry in the shade.Nature and flavor suffering, sweet, temperature.Return liver, kidney channel.Has kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Be used for impotence and seminal emission, the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension disease.
Fructus Lycii: be the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Summer, two season of autumn gather when fruit is orange red, dry in the air to rhicnosis, tan by the sun again stiff to crust, sarcocarp is soft, removes carpopodium; Or the hot blast oven drying at low temperature, remove carpopodium.Nature and flavor are sweet, and are flat.Return liver, kidney channel.Has nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Fructus Corni: be the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus officinalis Sieb.et Zucc..The picking fruit when time of the year when autumn changes into winter, peel reddened with slow fire baking or put after the boiling water part omitted scalds, in time removes removal core, drying.Nature and flavor acid, puckery, tepor.Return liver, kidney channel.Has liver and kidney tonifying, essence astringing and desertion stemming.Be used for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, the profuse sweating collapse, interior-heat is quenched one's thirst.
Hirudo: be the dry body of Hirudinidae animal whitmania Whitmania pigra Whitman, Hirudo Hirudo nipponicaWhitman or Folium Salicis Babylonicae Hirudo Whitmania acranulata Whitman.Summer, Qiu Erji catch, and scald extremely with boiling water, dry or cold drying.Nature and flavor are salty, bitter, and are flat; Poisonous.Return Liver Channel.Have removing blood stasis, removing blood stasis stimulates the menstrual flow.Be used for the abdominal mass mass in the abdomen, blood stasis amenorrhea, traumatic injury.
Radix Pseudostellariae: be the dried root of pinkwort Radix Ginseng Pseudostellaria heterophylla (Miq.) Pax exPax et Hoffm..Excavate during most of the withering of stem and leaf in summer, clean, remove fibrous root, put and dry or directly dry after the boiling water part omitted is scalded.Sweet, the little hardship of nature and flavor, flat.Return spleen, lung meridian.Has replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.It is tired to be used for insufficiency of the spleen body, and inappetence is weak after being ill, deficiency of both vital energy and Yin, and spontaneous perspiration is thirsty, dryness of the lung dry cough.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Autumn end excavates, and removes fibrous root and silt, treat that moisture evaporates slightly after, tie into wisp, last canopy is with pyrotechnics smoke-dried beancurd slowly.Nature and flavor are sweet, hot, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Radix Et Rhizoma Rhei: be the dry root and rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.The nature and flavor hardship, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Has purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.Be used for the conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay eliminating fire and detoxication.Be used for pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.Be used for heat in blood stasis of blood hemorrhage is arranged.
Caulis Spatholobi: be the dry rattan of leguminous plant spatholobus suberectus Spatholobus suberectus Dunn.Autumn, two seasons of winter gather, and remove branch and leaf, and section is dried.Nature and flavor hardship, sweet, temperature.Return liver, kidney channel.Have and enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Pharmaceutical composition of the present invention is made by the following weight Chinese medicinal raw materials: (every pair of Chinese medicine)
The Rhizoma Anemarrhenae 3～12 grams, Carapax et Plastrum Testudinis 3～18 grams, Cornu Cervi tablet 3～18 grams, Hippocampus 0.2～4 gram,
Radix Scutellariae 3～18 grams, Herba Epimedii 3～30 grams, Fructus Lycii 3～18 grams, Fructus Corni 2～12 grams,
Hirudo 1～10 gram, Radix Pseudostellariae 3～18 grams, Radix Angelicae Sinensis 3～18 grams, Radix Et Rhizoma Rhei 1～10 gram,
Caulis Spatholobi 3～18 grams
The raw material of Chinese medicine preferred weight proportioning of preparation pharmaceutical composition of the present invention is
The Rhizoma Anemarrhenae 6～9 grams, Carapax et Plastrum Testudinis 6～9 grams, Cornu Cervi tablet 3～9 grams, Hippocampus 0.6～2 gram,
Radix Scutellariae 9～15 grams, Herba Epimedii 15～30 grams, Fructus Lycii 6～9 grams, Fructus Corni 6～9 grams,
Hirudo 3～6 grams, Radix Pseudostellariae 10～12 grams, Radix Angelicae Sinensis 6～9 grams, Radix Et Rhizoma Rhei 3～9 grams,
Caulis Spatholobi 9～15 grams
The raw material of Chinese medicine optimum weight proportioning of pharmaceutical composition of the present invention is
The Rhizoma Anemarrhenae 12 grams, Carapax et Plastrum Testudinis 18 grams, Cornu Cervi tablet 18 grams, Hippocampus 0.6 gram, Radix Scutellariae 18 grams, Herba Epimedii 30 grams, Fructus Lycii 18 grams, Fructus Corni 12 grams, Hirudo 3 grams, Radix Pseudostellariae 18 grams, Radix Angelicae Sinensis 6 grams, Radix Et Rhizoma Rhei 3 grams, Caulis Spatholobi 9 grams.
Above-mentioned each component is made preparation of drug combination method of the present invention is:
With Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten powder 3-5 and doubly measures and decoct 2 times, each after 1-1.5 hour, the leaching filtrate for later use; Residue adds all the medical material 60-75% ethanol except that Hippocampus again, and 6-8 doubly measures reflux, extract, 2 times, each 1-2h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor; Add water extracts such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract; Adding fully behind the mixing, is beaten powder through being ground into the Hippocampus powder of fine powder, adds adjuvant and makes granule, capsule or tablet.
The specific embodiment
Embodiment 1
By following weight proportion,
The Rhizoma Anemarrhenae 3 grams, Carapax et Plastrum Testudinis 3 grams, Cornu Cervi tablet 3 grams, Hippocampus 0.2 gram, Radix Scutellariae 3 grams, Herba Epimedii 3 grams, Fructus Lycii 3 grams, Fructus Corni 2 grams, Hirudo 1 gram, Radix Pseudostellariae 3 grams, Radix Angelicae Sinensis 3 grams, Radix Et Rhizoma Rhei 1 gram, Caulis Spatholobi 3 grams.
With Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten 5 times of amounts of powder and decocts 2 times, after each 2 hours, the leaching filtrate for later use.Residue adds all medical material 60% ethanol except that Hippocampus again, measures reflux, extract, 2 times for 6 times, each 2h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor.Add water extracts such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract.Adding fully behind the mixing, is beaten powder through being ground into the Hippocampus powder of fine powder, adds adjuvant and makes granule.
Embodiment 2
By following weight proportion,
The Rhizoma Anemarrhenae 9 grams, Carapax et Plastrum Testudinis 9 grams, Cornu Cervi tablet 9 grams, Hippocampus 2 grams, Radix Scutellariae 9 grams, Herba Epimedii 15 grams, Fructus Lycii 9 grams, Fructus Corni 6 grams, Hirudo 6 grams, Radix Pseudostellariae 12 grams, Radix Angelicae Sinensis 18 grams, Radix Et Rhizoma Rhei 9 grams, Caulis Spatholobi 15 grams.
During the preparation method of this Chinese medicine composition with Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten 4 times of amounts of powder and decocts 2 times, after each 1.5 hours, the leaching filtrate for later use.Residue adds all medical material 70% ethanol except that Hippocampus again, measures reflux, extract, 2 times for 8 times, each 1.5h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor.Add water extracts such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract.Adding fully behind the mixing, is beaten powder through being ground into the Hippocampus powder of fine powder, adds adjuvant and makes granule, capsule or tablet.
Embodiment 3
By following weight proportion,
The Rhizoma Anemarrhenae 6 grams, Carapax et Plastrum Testudinis 6 grams, Cornu Cervi tablet 9 grams, Hippocampus 4 grams, Radix Scutellariae 15 grams, Herba Epimedii 15 grams, Fructus Lycii 6 grams, Fructus Corni 9 grams, Hirudo 10 grams, Radix Pseudostellariae 10 grams, Radix Angelicae Sinensis 9 grams, Radix Et Rhizoma Rhei 10 grams, Caulis Spatholobi 18 grams.
During the preparation method of this Chinese medicine composition with Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten 3 times of amounts of powder and decocts 2 times, after each 1 hour, the leaching filtrate for later use.Residue adds all medical material 60% ethanol except that Hippocampus again, measures reflux, extract, 2 times for 7 times, each 1.5h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor.Add water extracts such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract.Adding fully behind the mixing, is beaten powder through being ground into the Hippocampus powder of fine powder, adds adjuvant and makes granule, capsule or tablet.
Embodiment 4
By following weight proportion,
The Rhizoma Anemarrhenae 12 grams, Carapax et Plastrum Testudinis 18 grams, Cornu Cervi tablet 18 grams, Hippocampus 0.6 gram, Radix Scutellariae 18 grams, Herba Epimedii 30 grams, Fructus Lycii 18 grams, Fructus Corni 12 grams, Hirudo 3 grams, Radix Pseudostellariae 18 grams, Radix Angelicae Sinensis 6 grams, Radix Et Rhizoma Rhei 3 grams, Caulis Spatholobi 9 grams.
During the preparation method of this Chinese medicine composition with Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten powder 3-5 and doubly measures and decoct 2 times, after each 1 hour, the leaching filtrate for later use.Residue adds all medical material 75% ethanol except that Hippocampus again, measures reflux, extract, 2 times for 6.5 times, each 1h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor.Add water extracts such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract.Adding fully behind the mixing, is beaten powder through being ground into the Hippocampus powder of fine powder, adds adjuvant and makes granule, capsule or tablet.
Claims (5)
1, a kind of Chinese medicine composition for the treatment of infertility is characterized in that it being to be made by following materials of weight proportions:
The Rhizoma Anemarrhenae 3～12 grams, Carapax et Plastrum Testudinis 3～18 grams, Cornu Cervi tablet 3～18 grams, Hippocampus 0.2～4 gram,
Radix Scutellariae 3～18 grams, Herba Epimedii 3～30 grams, Fructus Lycii 3～18 grams, Fructus Corni 2～12 grams,
Hirudo 1～10 gram, Radix Pseudostellariae 3～18 grams, Radix Angelicae Sinensis 3～18 grams, Radix Et Rhizoma Rhei 1～10 gram,
Caulis Spatholobi 3～18 grams.
2, by the Chinese medicine composition of the described treatment infertility of claim 1, wherein the weight proportion of each raw material is:
The Rhizoma Anemarrhenae 6～9 grams, Carapax et Plastrum Testudinis 6～9 grams, Cornu Cervi tablet 3～9 grams, Hippocampus 0.6～2 gram,
Radix Scutellariae 9～15 grams, Herba Epimedii 15～30 grams, Fructus Lycii 6～9 grams, Fructus Corni 6～9 grams,
Hirudo 3～6 grams, Radix Pseudostellariae 10～12 grams, Radix Angelicae Sinensis 6～9 grams, Radix Et Rhizoma Rhei 3～9 grams,
Caulis Spatholobi 9～15 grams.
3, by the Chinese medicine composition of the described treatment infertility of claim 1, wherein the weight proportion of each raw material is:
The Rhizoma Anemarrhenae 12 grams, Carapax et Plastrum Testudinis 18 grams, Cornu Cervi tablet 18 grams, Hippocampus 0.6 gram, Radix Scutellariae 18 grams,
Herba Epimedii 30 grams, Fructus Lycii 18 grams, Fructus Corni 12 grams, Hirudo 3 grams, Radix Pseudostellariae 18 grams,
Radix Angelicae Sinensis 6 grams, Radix Et Rhizoma Rhei 3 grams, Caulis Spatholobi 9 grams.
4, by the Chinese medicine composition of the described treatment infertility of claim 1, it is characterized in that described pharmaceutical dosage form is granule, capsule or tablet.
5. the preparation method of the Chinese medicine composition of the treatment infertility of claim 1 is characterized in that being undertaken by following step:
1) with Carapax et Plastrum Testudinis, Hirudo, Cornu Cervi adds water to be beaten powder 3-5 and doubly measures and decoct 2 times, each after 1-1.5 hour, the leaching filtrate for later use;
2) residue adds all the medical material 60-75% ethanol except that Hippocampus, and 6-8 doubly measures reflux, extract, 2 times, each 1-2h, and leaching filtrate, filtrate are recycled to does not have the alcohol flavor;
3) add water extract such as Carapax et Plastrum Testudinis, be concentrated into the about thick paste that makes into more than 1.3 of density, in vacuum oven to dry extract;
4) add through being ground into the Hippocampus powder of fine powder, fully behind the mixing, beat powder, add adjuvant and make granule, capsule or tablet.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101569670B (en) * | 2008-05-04 | 2011-04-20 | 黄艺华 | Pharmaceutical composition for treating barrenness |
| CN104840545A (en) * | 2015-05-22 | 2015-08-19 | 常玉婷 | Traditional Chinese medicinal composition for treating phlegm-damp obstructive infertility |
| CN105142638A (en) * | 2013-03-15 | 2015-12-09 | 维罗纳制药公司 | Drug combination |
| EA030059B1 (en) * | 2017-08-17 | 2018-06-29 | Мария Владимировна Шаблий | Method for pregestation preparation of female patients with anti-phospholipide syndrome |
-
2005
- 2005-06-17 CN CNA2005100793220A patent/CN1843453A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101569670B (en) * | 2008-05-04 | 2011-04-20 | 黄艺华 | Pharmaceutical composition for treating barrenness |
| CN105142638A (en) * | 2013-03-15 | 2015-12-09 | 维罗纳制药公司 | Drug combination |
| CN104840545A (en) * | 2015-05-22 | 2015-08-19 | 常玉婷 | Traditional Chinese medicinal composition for treating phlegm-damp obstructive infertility |
| EA030059B1 (en) * | 2017-08-17 | 2018-06-29 | Мария Владимировна Шаблий | Method for pregestation preparation of female patients with anti-phospholipide syndrome |
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