CN104666654A

CN104666654A - Traditional Chinese medicine composition for treating yin and yang deficiency diabetes and preparation method of traditional Chinese medicine composition

Info

Publication number: CN104666654A
Application number: CN201510110998.5A
Authority: CN
Inventors: 陈彬
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-03-15
Filing date: 2015-03-15
Publication date: 2015-06-03

Abstract

The invention discloses traditional Chinese medicine composition for treating yin and yang deficiency diabetes and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is characterized by being prepared from the following medicinal materials in parts by weight: 10-25 parts of raphanus sativus, 5-20 parts of radix puerariae, 10-25 parts of calabash, 7-20 parts of elaeagnus pungens, 6-15 parts of enphoria longan flower, 5-20 parts of alfalfa, 15-30 parts of prepared rehmannia root, 7-20 parts of cuscuta chinensis, 7-20 parts of yew, 3-12 parts of rose apple seed, 5-20 parts of cynomorium songaricum, 3-12 parts of largeleaf curculigo rhizome, 5-20 parts of achyranthes bidentata, 7-20 parts of vine and 3-12 parts of liquorice. The traditional Chinese medicine composition is used for treating the yin and yang deficiency diabetes, and is high in efficiency and reliable in curative effect; and the diabetes does not relapse after healing.

Description

A kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes and preparation method thereof.

Background technology

The metabolic disease of diabetes to be one group with hyperglycemia be feature.Its occurrence cause mainly contain following some: 1., eating and drinking without temperance.Surfeit delicious food, pure wine savoury, impairing the spleen and stomach, dysfunction of the spleen in transportation, leads to interior-heat, and rapid digestion of food consumption essence, sends out as quenching one's thirst.2., feelings will is uncomfortable.Overaction of the five emotions, strongly fragrant and fire-transformation, disappear bright body fluid, and initiation is quenched one's thirst.3., work and rest mistake degree.The people that the ferritic deficiency of YIN, the five internal organs are weak, work and rest mistake degree, chamber is forfeited one's integrity, bringing about the spread of body fluid's loss, and kidney yin is impaired, and kidney loses astringency inducing, precise and tiny bet, therefore disappears under being.Its clinical manifestation is asymptomatic in early days, develops into the symptom phase, can occur polydipsia, polyphagia, polyuria, tired, the syndrome such as to become thin clinically, time serious, ketoacidosis occur.Diabetes are not fearful, and fearful is diabetic complication, so treatment diabetes are imperative.At present, the treatment of diabetes mainly contains western medicine, treatment by Chinese herbs, insulinize.The treatment of long-term hypoglycemic medicine can produce burden to liver kidney and other organs, and therapeutic effect worse and worse.Although insulinize effectively can control blood glucose, along with the development of the state of an illness, consumption can get more and more, and is difficult to the complication stopping diabetes.The traditional Chinese medical science effectively can be treated and be improved diabetes clinical symptoms, corrects lipid metabolic disorder in time, helps the discharge of abnormal sugar, protein, lipid metabolism product, effectively can prevent and treat complication.The different times of the femur head necrosis that the traditional Chinese medical science causes according to different reason and progression of disease, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: deficiency of YIN dryness-heat type, type of deficiency of both QI and YIN, deficiency of both YIN and YANG type, blood stasis accompanied symptoms type, negative and positive type wild.At present, the Chinese medicine for the treatment of diabetes has multiple, but the Chinese medicine being directed to treatment yang-yin asthenia type diabetes is actually rare, but also there is the defects such as cure rate is low.

Summary of the invention

For solving above-mentioned existing shortcoming, main purpose of the present invention is Chinese medicine composition of the treatment yang-yin asthenia type diabetes providing a kind of practicality and preparation method thereof, by selecting suitable medical material and proportioning thereof, reach the object of safe and effective healing yang-yin asthenia type diabetes.

For reaching above-described object, one of the present invention is treated yang-yin asthenia type diabetes and preparation method thereof and is taked following technical scheme:

Treat a Chinese medicine composition for yang-yin asthenia type diabetes, it is characterized in that, be made up of the medical material of following weight proportion:

Radix Raphani 10-25 part, Radix Puerariae 5-20 part, Pericarpium Lagenariae sicerariae 10-25 part, Fructus Elaeagni 7-20 part, Flos Longan 6-15 part, Herba Medicaginis 5-20 part, Radix Rehmanniae Preparata 15-30 part, Semen Cuscutae 7-20 part, Ramulus et folium taxi cuspidatae 7-20 part, Semen syzygii 3-12 part, Herba Cynomorii 5-20 part, Rhizoma Curculiginis Capitulatae 3-12 part, Radix Achyranthis Bidentatae 5-20 part, Caulis et Folium piperis 7-20 part, Radix Glycyrrhizae 3-12 part.

The present invention is a kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes preferably, it is characterized in that, is made up of the medical material of following weight proportion:

Radix Raphani 15-20 part, Radix Puerariae 10-15 part, Pericarpium Lagenariae sicerariae 15-20 part, Fructus Elaeagni 12-15 part, Flos Longan 9-12 part, Herba Medicaginis 10-15 part, Radix Rehmanniae Preparata 20-25 part, Semen Cuscutae 12-15 part, Ramulus et folium taxi cuspidatae 12-15 part, Semen syzygii 6-9 part, Herba Cynomorii 10-15 part, Rhizoma Curculiginis Capitulatae 6-9 part, Radix Achyranthis Bidentatae 10-15 part, Caulis et Folium piperis 12-15 part, Radix Glycyrrhizae 6-9 part.

A kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes of the best of the present invention, is characterized in that, be made up of the medical material of following weight proportion:

Radix Raphani 17 parts, Radix Puerariae 13 parts, Pericarpium Lagenariae sicerariae 17 parts, Fructus Elaeagni 13 parts, Flos Longan 10 parts, Herba Medicaginis 12 parts, Radix Rehmanniae Preparata 22 parts, Semen Cuscutae 13 parts, Ramulus et folium taxi cuspidatae 14 parts, Semen syzygii 8 parts, Herba Cynomorii 13 parts, Rhizoma Curculiginis Capitulatae 8 parts, Radix Achyranthis Bidentatae 12 parts, Caulis et Folium piperis 14 parts, 8 parts, Radix Glycyrrhizae.

A kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes of the present invention, is characterized in that, adopts following method to prepare:

A: take the Radix Raphani of weight proportion, Radix Puerariae, Pericarpium Lagenariae sicerariae, Fructus Elaeagni, Flos Longan, Herba Medicaginis, Radix Rehmanniae Preparata, Semen Cuscutae, Ramulus et folium taxi cuspidatae, Semen syzygii, Herba Cynomorii, Rhizoma Curculiginis Capitulatae, Radix Achyranthis Bidentatae, Caulis et Folium piperis and Radix Glycyrrhizae for subsequent use;

B: above-mentioned ten gomi herbs are poured in vessel, whole grinding becomes end, then uses " whole part " method to extract and makes instant Chinese medicine granule;

C: carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Source and the function of medical material involved in formula cure mainly as follows:

Radix Raphani [source] medical material Ji Yuan: to blossom and bear fruit old root for crucifer Lay takes Raphanus sativus L..[nature and flavor] are sweet; Pungent; Flat [return through] lung; Kidney channel [function cures mainly] circulation of qi promoting removing food stagnancy, reduces phlegm, quenches one's thirst, inducing diuresis to remove edema.Main cough with copious phlegm; Stagnation of QI due to dyspepsia; Abdominal distention feeling of fullness; Dysentery; Quench one's thirst; Beriberi, edema.

Radix Puerariae [source] medical material Ji Yuan: be the tuber of legume pueraria lobata or Radix Puerariae rattan.[nature and flavor] are sweet; Pungent; Flat [return through] spleen; Stomach; Lung; Urinary bladder channel [function cures mainly] expelling pathogenic factors from muscles for reducing heat; Deliver and examine; Promoting the production of body fluid to quench thirst; Yang invigorating antidiarrheal.Main fever caused by exogenous pathogens; Rigidity pain on the head and nape; Measles from the beginning of; Rash goes out not smooth; Epidemic febrile disease is thirsty; Diabetes; Have loose bowels; Dysentery; Hypertension; Coronary heart disease.

Pericarpium Lagenariae sicerariae [source] medical material Ji Yuan: be the fruit of cucurbitaceous plant calabash, calabash courd.[nature and flavor] sweet in the mouth; Light; Property flat [return through] return lung; Spleen; Kidney channel [function cures mainly] diuretic; Detumescence; Logical woods; Eliminating stagnation.Main edema; Ascites; Jaundice; Quench one's thirst; Gonorrhea; Carbuncle.

Fructus Elaeagni [source] medical material Ji Yuan: be the fruit of Elaeangnaceae plant Fructus Elaeagni.[nature and flavor] acid; Puckery; Flat [return through] lung; Stomach; Large intestine channel [function cures mainly] astringing to arrest diarrhea; Strengthening the spleen to promote digestion; Relieving cough and asthma; Hemostasis.Master has loose bowels; Dysentery; Inappetence; Dyspepsia; Cough and asthma; Metrorrhagia; Hemorrhoid hematochezia.

Flos Longan [source] medical material Ji Yuan: be the flower of sapindaceous plant Arillus Longan Dimocarpus longan Lour..[nature and flavor] micro-hardship; Sweet; Flat [return through] lung; Kidney channel [function cures mainly] treating stranguriaization is turbid.Main stranguria; Nebulousurine; Leucorrhea; Quench one's thirst.

Herba Medicaginis [source] medical material Ji Yuan: be the herb of dicotyledon medicine leguminous plant alfalfa or medicago hispida.[nature and flavor] are bitter; Flat; Nontoxic [return through] spleen; Stomach; The clear taste of kidney channel [function cures mainly]; Clearing away damp-heat; Diuresis; Detumescence.Main urinary stone; Vesical calculus; Edema; Stranguria; Quench one's thirst.

Radix Rehmanniae Preparata [source] medical material Ji Yuan: be the tuber of scrophulariaceae rehmannia glutinosa plant, steams solarization through processing and forms.[nature and flavor] sweet in the mouth; [return through] warm in nature returns liver; Kidney channel [function cures mainly] is enriched blood moist; Benefit essence fills out marrow.Main blood tiger is sallow; Dizzy cardiopalmus; Menoxenia; Collapse more than; Hepatic and renal YIN deficiency; Hectic fever night sweat; Seminal emission sexual impotence; Infertility; Soreness of the waist and knees; Hiccough and deaf; The head is dim-sighted; Early whitening of beard and hair; Quench one's thirst; Constipation; To suffer from a deficiency of the kidney dyspnea with rapid and short breath.

Semen Cuscutae [source] medical material Ji Yuan: be the seed of dicotyledon scammonia section plant Semen Cuscutae, Cuscuta australis, cuscuta japonica Choisy etc.[nature and flavor] Xin Gan; Flat [return through] liver; Kidney; Spleen channel [function cures mainly] the kidney invigorating and essence nourishing; Nourishing the liver to improve visual acuity; Gu tire stopping leak.Main soreness of waist and knee joint; Seminal emission; Sexual impotence; Premature ejaculation; Sterile; Quench one's thirst; Stranguria with turbid discharge; The enuresis; Blurred vision tinnitus; Frequent fetal movement; Miscarriage; Have loose bowels.

Ramulus et folium taxi cuspidatae [source] medical material Ji Yuan: be the leaf of taxaceae plant Ramulus et folium taxi cuspidatae.[nature and flavor] are light; Property flat [return through] kidney channel [function cures mainly] inducing diuresis to remove edema.Main nephritis edema; Dysuria; Diabetes.

Semen syzygii [source] medical material Ji Yuan: be the seed of myrtle Jambul.[nature and flavor] sweet in the mouth; Micro-acid; [return through] cool in nature returns stomach; Spleen channel [function cures mainly] spleen invigorating; Antidiarrheal.Main diarrhea due to hypofunction of the spleen; Chronic dysentery; Diabetes.

Herba Cynomorii [source] medical material Ji Yuan: be the fleshy stem of Cynomoriaceae plant Herba Cynomorii.[nature and flavor] sweet in the mouth; [return through] warm in nature returns kidney; Liver; Large intestine channel [function cures mainly] kidney invigorating and YANG supporting; The relieving constipation of benefit intestinal.Main impotence due to deficiency of the kidney; Seminal emission premature ejaculation; Flaccidity and weakness of the lower limbs; Empty people's constipation.

Rhizoma Curculiginis Capitulatae [source] medical material Ji Yuan: be the rhizome of bloodwort great Ye Rhizoma Curculiginis.[nature and flavor] are pungent; Micro-hardship; Temperature [return through] kidney; Lung; Liver Channel [function cures mainly] kidney invigorating and YANG supporting; Expelling wind and removing dampness; Promoting blood flow to regulate menstruation.Main cough with asthma of suffering from a deficiency of the kidney; Impotence and seminal emission; Nebulousurine leukorrhagia; Soreness of the waist and knees; Rheumatic arthralgia; Cold womb is infertile; Menoxenia; Metrorrhagia; Uterine prolapse; Traumatic injury.

Radix Achyranthis Bidentatae [source] medical material Ji Yuan: be the root of amaranthaceous plant Radix Achyranthis Bidentatae.[nature and flavor] are bitter; Acid; Property flat [return through] liver; Kidney channel [function cures mainly] invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Draw enemy state's (fire) descending; Inducing diuresis for treating stranguria syndrome.Main soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Levy abdominal mass; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.

Caulis et Folium piperis [source] medical material Ji Yuan: be stem and leaf or the Herb of Piperaceae phytobezoar Caulis et Folium piperis.[nature and flavor] are pungent; Temperature; Sweet [return through] liver; Spleen; Small intestine meridian [function cures mainly] wind-damp dispelling; Strong waist knee joint; Kidney invigorating and YANG supporting; Relieving cough and asthma; Promoting blood circulation and stopping pain.Main anemofrigid-damp arthralgia; Soreness of waist and knee joint; Sexual impotence; Cough and asthma; Dysmenorrhea; Treating swelling and pain by traumatic injury.

Radix Glycyrrhizae [source] this product is glycyrrhizic legume., Glycyrrhiza inflata Bat.. or the dry root of Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The weak spontaneous perspiration of yang-yin asthenia type diabetes, coldness of the body with chills, soreness of the waist and knees, helix parch, polydipsia polyuria, muddy as cream, or edema oliguria, or diarrhoea, impotence and premature ejaculation, pale tongue with white fur, deep,thready and forceless pulse.Above various raw material is organically combined by the present invention, mutually coordinates between each composition, interacts, can treating both the principal and secondary aspects of a disease to yang-yin asthenia type diabetes, respond well, fundamentally treats this disease.For many years, by the follow-up investigation statistics to 90 these type of patients of example, show that this prescription effective percentage reaches 95.5%.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, sampling approach

Be diagnosed as the patient of yang-yin asthenia type diabetes from my unit over nearly 5 years, the routine patient of random selecting 90, in age 15-60 year, be divided into matched group and treatment group at random, often organize each 45 people.The data there was no significant differences such as two groups of ages, have comparability.

2, test method

2.1 matched group patients use gliclazide, and by specification is taken, 6 weeks courses for the treatment of.

The oral the present invention of 2.2 treatment group according to the obtained Chinese medicinal granule of specific embodiment 1, early, middle and late each once.6 weeks courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterions of therapeutical effect:

Clinical recovery: clinical symptoms, the sign of yang-yin asthenia type diabetes disappear or substantially disappear; Effective: clinical symptoms, the sign of yang-yin asthenia type diabetes are obviously improved; Effective: clinical symptoms, the sign of yang-yin asthenia type diabetes all take a favorable turn; Invalid: clinical symptoms, the sign of yang-yin asthenia type diabetes are all not improved or increase the weight of.

3.2 treatment statistical results are in table 1.

Table 1 liang group comparitive study

Enumerate three model cases below and further illustrate effect of the present invention:

1, in certain, man, nineteen sixty is born, 52 years old, diabetes medical history 6 years, fasting glucose 12.2mmol/L, and with weak spontaneous perspiration, polydipsia polyuria, muddiness as cream, glimepiride therapy, glycemic control is not obvious, is diagnosed as yang-yin asthenia type diabetes in here.After taking 1 course for the treatment of of this prescription, symptom is alleviated to some extent, and after 2 courses for the treatment of, symptom obviously alleviates, and after 3 courses for the treatment of, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

2, Wang, man, birth in 1970,39 years old, coldness of the body with chills, soreness of the waist and knees, helix parch, frequent impotence and premature ejaculation, routine urianlysis ketoboidies (++), random blood sugar 22.2 mmol/L, was diagnosed as yang-yin asthenia type diabetes in here.After taking 1 course for the treatment of of this prescription, its remission, after 2 courses for the treatment of, symptom is obviously alleviated, after take again 2 courses for the treatment of continuously, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

3, Wu, man, birth in 1948,62 years old, diabetes medical history 5 years, anasarca, oliguria, often suffered from diarrhoea, and post-prandial glycemia 20 mmol/L, is diagnosed as yang-yin asthenia type diabetes in here.After taking 1 course for the treatment of of this prescription, symptom is namely basic to disappear, after take again 1 course for the treatment of and carried out after treatment, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

Detailed description of the invention

In order to Comprehension and Implementation the present invention better, below in conjunction with the concrete example implemented, further detailed description is done to the present invention.

Embodiment 1

Take Radix Raphani 15 grams, Radix Puerariae 10 grams, Pericarpium Lagenariae sicerariae 15 grams, Fructus Elaeagni 12 grams, Flos Longan 9 grams, Herba Medicaginis 10 grams, Radix Rehmanniae Preparata 20 grams, Semen Cuscutae 12 grams, Ramulus et folium taxi cuspidatae 12 grams, Semen syzygii 6 grams, Herba Cynomorii 10 grams, Rhizoma Curculiginis Capitulatae 6 grams, Radix Achyranthis Bidentatae 10 grams, Caulis et Folium piperis 12 grams, 6 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Be used for the treatment of yang-yin asthenia type diabetes.Oral, every bu is taken for early, middle and late three times.

Embodiment 2

Take Radix Raphani 17 grams, Radix Puerariae 13 grams, Pericarpium Lagenariae sicerariae 17 grams, Fructus Elaeagni 13 grams, Flos Longan 10 grams, Herba Medicaginis 12 grams, Radix Rehmanniae Preparata 22 grams, Semen Cuscutae 13 grams, Ramulus et folium taxi cuspidatae 14 grams, Semen syzygii 8 grams, Herba Cynomorii 13 grams, Rhizoma Curculiginis Capitulatae 8 grams, Radix Achyranthis Bidentatae 12 grams, Caulis et Folium piperis 14 grams, 8 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Embodiment 3

Take Radix Raphani 20 grams, Radix Puerariae 15 grams, Pericarpium Lagenariae sicerariae 20 grams, Fructus Elaeagni 15 grams, Flos Longan 12 grams, Herba Medicaginis 15 grams, Radix Rehmanniae Preparata 25 grams, Semen Cuscutae 15 grams, Ramulus et folium taxi cuspidatae 15 grams, Semen syzygii 9 grams, Herba Cynomorii 15 grams, Rhizoma Curculiginis Capitulatae 9 grams, Radix Achyranthis Bidentatae 15 grams, Caulis et Folium piperis 15 grams, 9 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Embodiment 4

Take Radix Raphani 10 grams, Radix Puerariae 5 grams, Pericarpium Lagenariae sicerariae 10 grams, Fructus Elaeagni 7 grams, Flos Longan 6 grams, Herba Medicaginis 5 grams, Radix Rehmanniae Preparata 15 grams, Semen Cuscutae 7 grams, Ramulus et folium taxi cuspidatae 7 grams, Semen syzygii 3 grams, Herba Cynomorii 5 grams, Rhizoma Curculiginis Capitulatae 3 grams, Radix Achyranthis Bidentatae 5 grams, Caulis et Folium piperis 7 grams, 3 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Embodiment 5

Take Radix Raphani 25 grams, Radix Puerariae 20 grams, Pericarpium Lagenariae sicerariae 25 grams, Fructus Elaeagni 20 grams, Flos Longan 15 grams, Herba Medicaginis 20 grams, Radix Rehmanniae Preparata 30 grams, Semen Cuscutae 20 grams, Ramulus et folium taxi cuspidatae 20 grams, Semen syzygii 12 grams, Herba Cynomorii 20 grams, Rhizoma Curculiginis Capitulatae 12 grams, Radix Achyranthis Bidentatae 20 grams, Caulis et Folium piperis 20 grams, 12 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

More than by description of listed embodiment, the basic ideas and basic principles of the present invention are set forth.But the present invention is never limited to above-mentioned listed embodiment, every equivalent variations, the improvement done based on technical scheme of the present invention and deliberately become of inferior quality behavior, all should belong to protection scope of the present invention.

Claims

1. treat a Chinese medicine composition for yang-yin asthenia type diabetes, it is characterized in that, be made up of the medical material of following weight proportion:

2. a kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes according to claim 1, is characterized in that, be made up of the medical material of following weight proportion:

3. a kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes according to claim 1, is characterized in that, be made up of the medical material of following weight proportion:

4., according to the arbitrary described a kind of Chinese medicine composition for the treatment of yang-yin asthenia type diabetes of claims 1 to 3, it is characterized in that, adopt following method to prepare: