CN1589813A - Chinese medicine for treating biabetes - Google Patents
Chinese medicine for treating biabetes Download PDFInfo
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- CN1589813A CN1589813A CN 03124760 CN03124760A CN1589813A CN 1589813 A CN1589813 A CN 1589813A CN 03124760 CN03124760 CN 03124760 CN 03124760 A CN03124760 A CN 03124760A CN 1589813 A CN1589813 A CN 1589813A
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Abstract
A Chinese medicine for treating diabetes, frequent urination, numb limbs, skin etching, etc is prepared from 8 Chinese-medicinal materials including dodder seed, cinammon bark, astragalus root, notoginseng, etc.
Description
Technical field
The invention belongs to the Chinese medicine of treatment diabetes.
Background technology
China Drug Administration is online announce in the recent period and the Chinese patent medicine of 85 years to 2000 approval production for treating diabetes in, its functions of the overwhelming majority are supplementing QI and nourishing YIN, clearing away heat and promoting production of body fluid cures mainly the medicine of deficiency of both QI and YIN or type of YIN-deficiency and interior-heat diabetes.These medicine blood sugar lowering effects are not obvious, can only cooperate Western medicine to use; And it is, undesirable as diabetic nephropathy, diabetes cardiovascular and cerebrovascular disease effect to diabetic complication; Also should not be applied to deficiency of both YIN and YANG, the syndrome of static blood blocking collaterals treatment of diabetes.Not seeing as yet in the prior art has with the nourishing kidney warming YANG, the Chinese patent medicine of disperse blood stasis and dredge collateral function prescription therapeutic deficiency of both YIN and YANG diabetes.
Summary of the invention
The purpose of this invention is to provide that a kind of blood sugar lowering effect is obvious, side effect is little, low price, have the nourishing kidney warming YANG, the disperse blood stasis and dredge collateral function both can be used for deficiency of both YIN and YANG, the treatment of diabetes of congestion resistance network card of holding concurrently; Effective control of diabetes complication again is as the Chinese patent medicine of diabetic nephropathy, the treatment of diabetes cardiovascular and cerebrovascular disease.
Chinese medicine of the present invention is made up of following medicine and weight ratio: by Semen Cuscutae 833-1000, and Herba Epimedii 417-500, Fructus Mori 417-500, Cortex Cinnamomi 250-300, Fructus Momordicae charantiae 417-500, Radix Puerariae 333-400, Radix Astragali 500-600, Radix Notoginseng 166-200 forms.And can by this basic side suitably the plus-minus prescription make and have the nourishing kidney warming YANG, the disperse blood stasis and dredge collateral function is used for deficiency of both YIN and YANG, the treatment of diabetes of congestion resistance network card of holding concurrently.
Chinese medicine of the present invention can be made granule, also can make tablet, capsule and other dosage form.
Medicine of the present invention after deliberation is suitable with the Western medicine JIANGZHILING PIAN to the blood sugar lowering curative effect of animal hyperglycemia model, but this product is without any side effects, has the characteristics of nourishing kidney warming YANG, activating blood circulation to dissipate blood stasis.To alleviating good preventive and therapeutic effect is arranged with control of diabetes complication-diabetic nephropathy, diabetes cardiovascular and cerebrovascular disease etc.
Pharmacodynamics test shows: medicine of the present invention does not have influence to normal mouse blood sugar.Can obviously reduce alloxan diabetes man rabbit blood glucose; Increase insulin level, reduce the pancreas high blood glucose concentrations; Has antioxidation; Can reduce the streptozotocin blood glucose in diabetic rats; Improve hemorheological property, have function of promoting blood circulation to disperse blood clots.Can improve the mice YANG asthenia disease due to the hydrocortisone, have tangible warming YANG effect.And can improve mice anoxia enduring survival ability, certain nourishing yin effect is arranged.Its high dose group hypoglycemic activity and Western medicine JIANGZHILING PIAN therapeutic equivalence.
This product acute toxicity test shows: observed none death of animal 7 days continuously for 176 times with clinical dosage.Long term toxicity test shows that 66.2 times of the usefulness clinical dosage are given rat continuous irrigation stomach, observes 6 months, obvious toxic and side effects do not occur.
By 20 routine clinical observations, take the blood sugar lowering TONGMAI KELI to the hold concurrently diabetics of congestion resistance network card of deficiency of both YIN and YANG, each 4g, every day 3 times, 4 weeks of logotype, other blood sugar lowering Chinese and western drugses of generally stopping using, the heavier person's Western medicine of state of an illness decrement is taken.The result: produce effects (blood glucose is reduced to normally) 7 examples, effective 12 examples, total effective rate is 95%, an invalid example.Hemogram, gastrointestinal tract etc. is not seen untoward reaction.Symptoms such as, numb hand and foot cold to frequent urination at night, the acid of waist knee joint, skin Pruritus, generally taking just had positive effect in 3-5 days.Can replace or partly replace diabetes treatment by western medicine.
The specific embodiment
Embodiment: the preparation of blood sugar lowering TONGMAI KELI:
1, get Semen Cuscutae 833g, Herba Epimedii 417g, Fructus Momordicae charantiae 417g, Radix Puerariae 333g, Radix Notoginseng 166g add alcohol reflux 2-3 time of 5 times of amount 60%-80%, filter, room temperature left standstill 12 hours, filtered out impurities, reclaim ethanol, and vacuum concentration is the thick paste of 1.25-1.30 to relative density;
2, get the water that Cortex Cinnamomi 250g adds 14 times of amounts, reflux extraction in 5 hours volatile oil, in 40 ℃ of stirring enclose, collection is filtered in cold preservation, gets clathrate, and is standby with the 8g cycloheptaamylose;
3, get Radix Astragali 500g, Fructus Mori 417g, add 8 times of water gaging heated and boiled 2.0 hours, filter with 200 order filters.Medicinal residues after above medicinal residues and above-mentioned Cortex Cinnamomi medicinal residues, the alcohol extraction are merged, add 7 times of water gagings and extracted 1.5 hours, filter with 100 order filters, filtrate.
4, the medicinal liquid that extracts behind the volatile oil of twice filtrate and Cortex Cinnamomi merges, and at temperature 65-70 ℃, being evaporated to relative density under the vacuum 0.06-0.08Mpa condition is the thick paste (about 1450g) of 1.15-1.20 (60 ℃).
5, Jiang Shui carries with alcohol extraction gained thick paste and merges (about 1920g), adds the 250g dextrin, mixing, and vacuum drying (temperature 60-70 ℃, vacuum 0.07-0.09Mpa) gets the about 920g of dry extract
6, add an amount of dextrin and be adjusted to 986g, pulverize.
7, get the beta-CD inclusion mix homogeneously that the above-mentioned medicated powder of 160g adds the 8g Cortex Cinnamomi volatile oil, with the about 60ml granulation of 92% ethanol that is dissolved with the 1g stevioside, about 50 ℃ air-dry.
8, residue medicated powder is granulated in right amount with dissolving 5g stevioside 92% ethanol, and 60-85 ℃ is dried to water content less than 3%, put cold, with the granule mix homogeneously that contains the Cortex Cinnamomi volatile oil beta-CD inclusion, approximately 1000g, pack with aluminum-plastic composite membrane, every bag of 4g approximately must 250 bags.
Claims (5)
1, a kind of Chinese medicine for the treatment of diabetes is characterized in that being made up of following medicine and weight ratio:
Semen Cuscutae 833-1000, Herba Epimedii 417-500, Fructus Mori 417-500, Cortex Cinnamomi 250-300, Fructus Momordicae charantiae 417-500, Radix Puerariae 333-400, Radix Astragali 500-600, Radix Notoginseng 166-200.
2, medicine according to claim 1 is characterized in that described medicine is the granule dosage form.
3, medicine according to claim 1 is characterized in that described medicine is a pill-type.
4, medicine according to claim 1 is characterized in that described medicine is a tablet form.
5, medicine according to claim 1 is characterized in that described medicine is a capsule formulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031247601A CN100493531C (en) | 2003-08-25 | 2003-08-25 | Chinese medicine for treating diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031247601A CN100493531C (en) | 2003-08-25 | 2003-08-25 | Chinese medicine for treating diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1589813A true CN1589813A (en) | 2005-03-09 |
| CN100493531C CN100493531C (en) | 2009-06-03 |
Family
ID=34597003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031247601A Expired - Fee Related CN100493531C (en) | 2003-08-25 | 2003-08-25 | Chinese medicine for treating diabetes |
Country Status (1)
| Country | Link |
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| CN (1) | CN100493531C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101507757B (en) * | 2009-04-03 | 2012-03-28 | 谢正杰 | Compound Chinese medicine for treating diabetes |
| CN102988726A (en) * | 2012-10-13 | 2013-03-27 | 慈溪市锐玛电子有限公司 | Medicament for treating diabetes |
| CN104666654A (en) * | 2015-03-15 | 2015-06-03 | 陈彬 | Traditional Chinese medicine composition for treating yin and yang deficiency diabetes and preparation method of traditional Chinese medicine composition |
| CN108853342A (en) * | 2018-10-12 | 2018-11-23 | 耿恩子 | A kind of Chinese medical extract that treating diabetes and preparation method |
-
2003
- 2003-08-25 CN CNB031247601A patent/CN100493531C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101507757B (en) * | 2009-04-03 | 2012-03-28 | 谢正杰 | Compound Chinese medicine for treating diabetes |
| CN102988726A (en) * | 2012-10-13 | 2013-03-27 | 慈溪市锐玛电子有限公司 | Medicament for treating diabetes |
| CN102988726B (en) * | 2012-10-13 | 2014-11-26 | 慈溪市锐玛电子有限公司 | Medicament for treating diabetes |
| CN104666654A (en) * | 2015-03-15 | 2015-06-03 | 陈彬 | Traditional Chinese medicine composition for treating yin and yang deficiency diabetes and preparation method of traditional Chinese medicine composition |
| CN108853342A (en) * | 2018-10-12 | 2018-11-23 | 耿恩子 | A kind of Chinese medical extract that treating diabetes and preparation method |
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| Publication number | Publication date |
|---|---|
| CN100493531C (en) | 2009-06-03 |
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Granted publication date: 20090603 Termination date: 20110825 |