CN1840000A - Nutrition oral liquor - Google Patents

Nutrition oral liquor Download PDF

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Publication number
CN1840000A
CN1840000A CNA2006100018053A CN200610001805A CN1840000A CN 1840000 A CN1840000 A CN 1840000A CN A2006100018053 A CNA2006100018053 A CN A2006100018053A CN 200610001805 A CN200610001805 A CN 200610001805A CN 1840000 A CN1840000 A CN 1840000A
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CN
China
Prior art keywords
radix
schisandrae chinensis
acanthopanacis senticosi
caulis acanthopanacis
fructus schisandrae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006100018053A
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Chinese (zh)
Inventor
李桂林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harbin Green Spring Biotechnology Research Institute
HARBIN GREEN SPRING FOOD CO Ltd
Original Assignee
Harbin Green Spring Biotechnology Research Institute
HARBIN GREEN SPRING FOOD CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbin Green Spring Biotechnology Research Institute, HARBIN GREEN SPRING FOOD CO Ltd filed Critical Harbin Green Spring Biotechnology Research Institute
Priority to CNA2006100018053A priority Critical patent/CN1840000A/en
Publication of CN1840000A publication Critical patent/CN1840000A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a nourishing oral liquid comprising donkey-hide gelatin as the main ingredient and bee honey as the modulating agent, as well as the following raw materials: acanthopanax root, schisandra fruit, prepared rehmannia root, haw and longan pulp. Its functions include nourishing blood, replenish vital essence, reinforcing the kidney and controlling nocturnal emission.

Description

Nutrition oral administration
Technical field
The present invention relates to utilize medical material to make nutrition oral administration.
Background technology
At present, have the oral liquid that utilizes Chinese medicinal herbs to make of numerous species, as be used for the motion and the body-building tonic of acid-base balance in the control agent, improve the beneficial recovery oral liquid of immune function of human body etc.Specific as follows: contain Radix Rehmanniae Preparata and Mel etc. in Mrs's oral liquid, it mainly acts on is the moisture of augmenting human body skin, has beauty functions, and main adaptation population is the adult female.As mainly containing Colla Corii Asini in the Colla Corii Asini nourishing blood oral liquid in the class oral liquid of enriching blood, be used for the human body blood deficiency; The benefiting QI and nourishing blood oral liquid is used for invigorating the liver and kidney, benefiting QI and nourishing blood, is fit to the physical weakness person; The Colla Corii Asini oral liquid that lengthens one's life for another example, the cardiopalmus that is suitable for breathing hard, lustreless complexion person.The effect of above-mentioned various oral liquids is single, and the adaptation population is limited, and to human immune system's regulating action not too.Another beneficial recovery oral liquid wherein contains immune polysaccharide, though have effects such as nourishing the liver and kidney, Yin Yang balancing, enhance immunity, promotion health, more unobvious to all kinds of disease patients' auxiliary curative effect, and to tumor patient without any auxiliary curative effect.
Summary of the invention
The invention provides and a kind ofly not only contain the multiple nutrients material, and have enrich blood, the liver protecting, resisting fatigue, defying age improve the nutrition oral administration of body immunity and antineoplastic effect.
Nutrition oral administration of the present invention includes major ingredient one Colla Corii Asini and modulator one Mel; And further include following raw material: Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis, Radix Rehmanniae Preparata, Fructus Crataegi and Arillus Longan; The weight following (to make oral liquid 10000ml) of each material:
Colla Corii Asini 450~550g;
Radix Et Caulis Acanthopanacis Senticosi 150~200g, Fructus Schisandrae Chinensis 100~150g, Radix Rehmanniae Preparata 120~200g, Fructus Crataegi 100~180g, Arillus Longan 50~100g;
Mel 3500~4200g.
Weight after the above-mentioned Fructus Crataegi enucleation.Above-mentioned Colla Corii Asini is to utilize the pure water self-control to form by donkey skin, and measuring its proportion at 80 ℃ is 1.25~1.30g/ml.
The manufacture method of nutrition oral administration of the present invention includes following process:
1. Radix Et Caulis Acanthopanacis Senticosi in the raw material and Fructus Schisandrae Chinensis are leached into cream respectively: the Radix Et Caulis Acanthopanacis Senticosi of required amount and Fructus Schisandrae Chinensis are used 40~70% ethanol lixiviates 48 hours respectively, reclaim ethanol, get Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis extractum respectively, this Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis extractum are measured when 80 ℃ of temperature, and its proportion is 1.18~1.20g/ml.Stand-by;
2. the preparation of condensed cream: said process 1. the Radix Et Caulis Acanthopanacis Senticosi after the lixiviate, Fructus Schisandrae Chinensis medicinal residues together with Radix Rehmanniae Preparata, Fructus Crataegi, the Arillus Longan of required amount, adding 4~10 times of water extracts concentrated in dynamic vacuum extraction concentration tank, to proportion be 1.18g/ml, condensed cream, stand-by;
3. prepare Colla Corii Asini: donkey skin is softening to donkey skin with the clear water soak at room temperature, take out and scrape off Pilus Equi Asini, be cut into small pieces, glue pot is put in the clear water rinsing, adding the pure water heating decocts for several times, get the 120 mesh sieves filtration while hot of upper strata Colloidal fluid, add in the proteolytic enzyme jacketed pan, concentrate with 0.1~0.15MPa, get the finished product Colla Corii Asini, stand-by;
4. modulate finished product: the required amount Colla Corii Asini that 3. process of getting prepares, and the condensed cream that 2. makes of the said process Radix Et Caulis Acanthopanacis Senticosi extractum, Fructus Schisandrae Chinensis extractum and the process that 1. make, together put into the vessel behind the disinfection, add Mel again, stir, add purified water again to required amount, stir, plate-and-frame filtration, canned, finished product is made in sterilization.
The described extraction at dynamic vacuum extracted the condition of concentrating and is in the concentration tank: steam 0.10~0.15MPa, vacuum-0.06,70~80 ℃ of temperature.
Oral liquid of the present invention is based on Colla Corii Asini (self-control), adds that medical materials such as Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis are refining to form.Contain rich in amino acid, protein, various trace elements, vitamin and corresponding alkaloid, biological glycosides etc.Effect with adjusting and runing yang, benefiting QI and nourishing blood, reinforcing the kindey to control nocturnal emission, mind tranquilizing and the heart calming, improvement integral body.Pharmacological evaluation is not seen any toxic and side effects.Be used for deficiency of both YIN and YANG, the heart due to insufficiency of vital energy and blood, Liver and kidney void are lost, spleen, kidney three are through the disorderly tcm symptom of lacking of proper care.This oral liquid blocks hemorrhage sequela, diabetes, gastrointestinal dysfunction, neurasthenia, rheumatic and rheumatoid, bronchial asthma, prostatosis, sexual dysfunction, menoxenia and immunologic hypofunction allomeric function imbalance syndrome, adolescence syndrome, climacteric syndrome, old syndrome and sub-health population to cardiovascular and cerebrovascular disease, arteriosclerosis, hyperlipidemia, high thickness mass formed by blood stasis, coronary heart disease, hypertension, cerebral thrombosis and has remarkable rehabilitative action; And to suppressing the tumor cyst, hypertrophy is anticancer, and operation is put, patients undergoing chemotherapy has tangible adjuvant treatment effect.
Colla Corii Asini of the present invention is to adopt free of contamination remote mountains mineral water, adds the liquid glue that the biological hydrolysis enzyme is directly made.Adopt vacuum and low temperature to extract and concentrate, kept the thermally labile active component to greatest extent; And the water quality that is adopted is rich in several mineral materials.
Nutrition oral administration of the present invention contains nutrition a large amount of, the human body needs.1, protein content height: after testing, wherein contained protein is greater than 4%.2, the aminoacid that contains multiple needed by human body: wherein lysine 0.16%, histidine 0.04%, arginine 0.29%, aspartic acid 0.26%, threonine 0.10%, serine 0.20%, glutamic acid 0.48%, proline 0.56%, glycine 1.03%, alanine 0.40%, valine 0.15%, cystine 0.18%, methionine 0.03%, leucine 0.16%, isoleucine 0.07%, tyrosine 0.11%, phenylalanine 0.17%.3, contain multiple metallic element: K, Na, Ca, Mg, Fe, Cu, Al, Mn, Zn, Cr, Pt, Pb, Mo, Sr etc.
The present invention confirms to have following function through zoopery and clinical experiment:
1, blood nourishing function.Because this nutrition oral administration contains a large amount of nutrient substance favourable to human body, as the aminoacid of various needed by human body, by its Nutrition to human body, to improve human body whole body function.RBC number and the hemoglobin content that increases blood there is certain help.
2, function such as the liver protecting.This oral liquid energy Ginkgo Biloba, facilitating digestion, promotion chyle absorb; Have and suppress fat deposition and promote hepatocyte new life's effect in hepatocyte, the liver protecting, prevent the effect that liver glycogen reduces.
3, anti-fatigue effect.This nutritional solution has been carried out resisting fatigue and hypoxia endurance test, and the result can both obviously prolong swimming time and mice time-to-live.
4, senile-resistant efficacy.Sudismase (SOD), hemoglobin (Hb) and lipid peroxide (LPO) content dynamic observes in the old human blood through taking this nutritional solution, oral front and back, the result of SOD, Hb and LPO assay shows in the body, takes obviously to raise before the SOD activity is taken medicine in the human body blood of back; Hb content obviously increases before taking medicine; Before taking, obviously reduces LPO content.Obviously have enhancing body vigor, the anti-ageing effect of waiting for a long time.
5, improve the body immunity effect.Empirical tests, this nutritional solution can obviously increase total rosette percentage rate of old people and T-lymhocyte transformation rate; Except that having the effect that improves body ability to work and elimination senile symptom, also have the peripheral leukocytes sum of increasing and neutrophil cell, to strengthen specific immunity, promote the effect of cellular immunization and part humoral immunization.
6, antitumor action.This nutritional solution directly enters and presses down tumor in the mice body and prolong experiment life cycle, and the tumour inhibiting rate of three experiments is respectively: 57.48%, 52.15%, 33.5%; In prolonging experiment life cycle, this nutritional solution can obviously prolong the life cycle of the mice of carrying tumor, and mouse storaging current has prolonged 168.64%; Irritate during excess of the stomach tests carrying tumor, agile, the gloss of mice performance, this nutritional solution can obviously improve life quality.
7, promote the calcium metabolism effect.Show that through the dog experiment this nutritional solution can promote the absorption of calcium, have positive calcium balance effect, be adapted to myodegeneration disease person.
8, radiation resistance.Mice survival rate on the 30th and radiation protection are renderd a service and be experiment showed, that matched group survival rate on the 30th is 0, administration group on the 3rd survival rate 20%, and protection renders a service 1.80; Administration group on the 7th survival rate 70%, protection renders a service 2.81, and is evident in efficacy.
The specific embodiment
One, nutrition oral administration
Nutrition oral administration of the present invention is characterized in that: it includes major ingredient-Colla Corii Asini and modulator-Mel; And further include following raw material: Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis, Radix Rehmanniae Preparata, Fructus Crataegi and Arillus Longan; The weight following (to make oral liquid 10000ml) of each material:
Colla Corii Asini 450~550g;
Radix Et Caulis Acanthopanacis Senticosi 150~200g, Fructus Schisandrae Chinensis 100~150g, Radix Rehmanniae Preparata 120~200g, Fructus Crataegi 100~180g, Arillus Longan 50~100g;
Mel 3500~4200g.
Described Fructus Crataegi is the weight behind removal crab apple or the nuclear.The weight of each raw material is dry weight.
Described Colla Corii Asini is to utilize the pure water self-control to form by donkey skin, and surveying its proportion at 80 ℃ is 1.25~1.30g/ml.
As the weight of each material of this nutrition oral administration, the best is selected for use following (to make oral liquid 10000ml):
Colla Corii Asini 500g;
Radix Et Caulis Acanthopanacis Senticosi 180g, Fructus Schisandrae Chinensis 125g, Radix Rehmanniae Preparata 160g, Fructus Crataegi 140g, Arillus Longan 75g;
Mel 3800g.
Two, the manufacture method of nutrition oral administration
Embodiment one
The manufacture method of nutrition oral administration of the present invention mainly comprises following process:
1. Radix Et Caulis Acanthopanacis Senticosi in the raw material and Fructus Schisandrae Chinensis are leached into cream respectively: get 150g Radix Et Caulis Acanthopanacis Senticosi and 100g Fructus Schisandrae Chinensis and use 50% ethanol lixiviate 48 hours respectively, reclaim ethanol, get Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis extractum 30g and 20g respectively.This Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis extractum are measured when 80 ℃ of temperature, and its proportion is respectively 1.18g/ml and 1.19g/ml, and is stand-by.
2. the preparation of condensed cream: said process 1. the Radix Et Caulis Acanthopanacis Senticosi after the lixiviate, Fructus Schisandrae Chinensis medicinal residues together with 120g Radix Rehmanniae Preparata, 100g Fructus Crataegi, 50g Arillus Longan, adding 5 times of water extracts concentrated in dynamic vacuum extraction concentration tank, steam 0.10~0.15MPa, vacuum-0.06,70~80 ℃ of temperature, concentrate about 18 hours to proportion be 1.18g/ml, condensed cream, stand-by;
3. prepare Colla Corii Asini: donkey skin is used clear water soak at room temperature 2~3 days, change water every day 3 times, after donkey skin is softening, take out and scrape off Pilus Equi Asini, be cut into the fritter about 15cm * 15cm, the clear water rinsing, make it fair and clear, put into glue pot, add pure water and submergence donkey skin, decoct with 0.1~0.15MPa Steam Heating, each 2 hours, totally 4 times, get the 120 mesh sieves filtration while hot of upper strata Colloidal fluid, add in the proteolytic enzyme jacketed pan, in vapour pressure is under the 0.08Mpa, concentrates, and gets the finished product Colla Corii Asini, this Colla Corii Asini is surveyed proportion at 80 ℃ and is 1.25~1.30g/ml, and is stand-by;
4. modulate finished product: the Colla Corii Asini 450g that 3. process of getting prepares, and the condensed cream that 2. makes of the said process Radix Et Caulis Acanthopanacis Senticosi extractum, Fructus Schisandrae Chinensis extractum and the process that 1. make, together put into the vessel (volume is greater than 10L) behind the disinfection, add Mel 3500g again, stir, add purified water again to 10L, stir, plate-and-frame filtration, canned, finished product 10L is made in sterilization.
Embodiment two:
The manufacture method of nutrition oral administration of the present invention mainly comprises following process:
1. Radix Et Caulis Acanthopanacis Senticosi in the raw material and Fructus Schisandrae Chinensis are leached into cream respectively: get 200g Radix Et Caulis Acanthopanacis Senticosi and 150g Fructus Schisandrae Chinensis and use 70% ethanol lixiviate 48 hours respectively, the recovery ethanol of heating gets Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis extractum 40g and 30g respectively.This Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis extractum are measured when 80 ℃ of temperature, and its proportion is 1.20g/ml, and is stand-by.
2. the preparation of condensed cream: said process 1. the Radix Et Caulis Acanthopanacis Senticosi after the lixiviate, Fructus Schisandrae Chinensis medicinal residues together with 200g Radix Rehmanniae Preparata, 180g Fructus Crataegi, 100g Arillus Longan, adding 8 times of water extracts concentrated in dynamic vacuum extraction concentration tank, steam 0.10~0.15MPa, vacuum-0.06,70~80 ℃ of temperature, concentrate about 18 hours to proportion be 1.18g/ml, condensed cream, stand-by;
3. prepare Colla Corii Asini: with embodiment one.
4. modulate finished product: the Colla Corii Asini 550g that 3. process of getting prepares, and the condensed cream that 2. makes of the process Radix Et Caulis Acanthopanacis Senticosi extractum, Fructus Schisandrae Chinensis extractum and the process that 1. make is put into the vessel behind the disinfection, adding Mel 4200g again stirs, add purified water again to 10L, stir, plate-and-frame filtration, canned, finished product 10L is made in sterilization.
Embodiment three:
The manufacture method of nutrition oral administration of the present invention mainly comprises following process:
1. Radix Et Caulis Acanthopanacis Senticosi in the raw material and Fructus Schisandrae Chinensis are leached into cream respectively: get 180g Radix Et Caulis Acanthopanacis Senticosi and 125g Fructus Schisandrae Chinensis and use 60% ethanol lixiviate 48 hours respectively, the recovery ethanol of heating gets Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis extractum 36g and 25g respectively.This Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis extractum are measured when 80 ℃ of temperature, and its proportion is 1.19g/ml, and is stand-by.
2. the preparation of condensed cream: said process 1. the Radix Et Caulis Acanthopanacis Senticosi after the lixiviate, Fructus Schisandrae Chinensis medicinal residues together with 160g Radix Rehmanniae Preparata, 140g Fructus Crataegi, 75g Arillus Longan, adding 7 times of water extracts concentrated in dynamic vacuum extraction concentration tank, steam 0.10~0.15MPa, vacuum-0.06,70~80 ℃ of temperature, concentrate about 18 hours to proportion be 1.18g/ml, condensed cream, stand-by;
3. prepare Colla Corii Asini: with embodiment one.
4. modulate finished product: the Colla Corii Asini 500g that 3. process of getting prepares, and the condensed cream that 2. makes of the process Radix Et Caulis Acanthopanacis Senticosi extractum, Fructus Schisandrae Chinensis extractum and the process that 1. make is put into the vessel behind the disinfection, adding Mel 3800g again stirs, add purified water again to 10L, stir, plate-and-frame filtration, canned, finished product 10L is made in sterilization.
Nutritional solution finished product detection of the present invention is carried out according to relevant criterion, and testing result all meets the requirements.

Claims (5)

1, nutrition oral administration is characterized in that: it includes major ingredient-Colla Corii Asini and modulator-Mel; And further include following raw material: Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis, Radix Rehmanniae Preparata, Fructus Crataegi and Arillus Longan; The weight following (to make oral liquid 10000ml) of each material:
Colla Corii Asini 450~550g;
Radix Et Caulis Acanthopanacis Senticosi 150~200g, Fructus Schisandrae Chinensis 100~150g, Radix Rehmanniae Preparata 120~200g, Fructus Crataegi 100~180g, Arillus Longan 50~100g;
Mel 3500~4200g.
2, nutrition oral administration according to claim 1 is characterized in that: above-mentioned Colla Corii Asini is to utilize the pure water self-control to form by donkey skin; It is 1.25~1.30g/ml that described Colla Corii Asini is surveyed proportion at 80 ℃.
3, nutrition oral administration according to claim 1 and 2 is characterized in that: the weight of described each material, and the best is selected for use following (to make oral liquid 10000ml):
Colla Corii Asini 500g;
Radix Et Caulis Acanthopanacis Senticosi 180g, Fructus Schisandrae Chinensis 125g, Radix Rehmanniae Preparata 160g, Fructus Crataegi 140g, Arillus Longan 75g;
Mel 3800g.
4, the manufacture method of nutrition oral administration is characterized in that: it includes following process:
1. Radix Et Caulis Acanthopanacis Senticosi in the raw material and Fructus Schisandrae Chinensis are leached into cream respectively: the Radix Et Caulis Acanthopanacis Senticosi of required amount and Fructus Schisandrae Chinensis are used 40~70% ethanol lixiviates 48 hours respectively, reclaim ethanol, get Radix Et Caulis Acanthopanacis Senticosi, Fructus Schisandrae Chinensis extractum respectively, this Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis extractum are measured when 80 ℃ of temperature, its proportion is 1.18~1.20g/ml, and is stand-by;
2. the preparation of condensed cream: said process 1. the Radix Et Caulis Acanthopanacis Senticosi after the lixiviate, Fructus Schisandrae Chinensis medicinal residues together with Radix Rehmanniae Preparata, Fructus Crataegi, the Arillus Longan of required amount, adding 4~10 times of water extracts concentrated in dynamic vacuum extraction concentration tank, to proportion be 1.18g/ml, condensed cream, stand-by;
3. prepare Colla Corii Asini: donkey skin is softening to donkey skin with the clear water soak at room temperature, take out and scrape off Pilus Equi Asini, be cut into small pieces, glue pot is put in the clear water rinsing, adding the pure water heating decocts for several times, get the 120 mesh sieves filtration while hot of upper strata Colloidal fluid, add in the proteolytic enzyme jacketed pan, concentrate with 0.1~0.15MPa, get the finished product Colla Corii Asini, stand-by;
4. modulate finished product: the required amount Colla Corii Asini that 3. process of getting prepares, and the condensed cream that 2. makes of the said process Radix Et Caulis Acanthopanacis Senticosi extractum, Fructus Schisandrae Chinensis extractum and the process that 1. make, together put into the vessel behind the disinfection, add Mel again, stir, add purified water again to required amount, stir, plate-and-frame filtration, canned, finished product is made in sterilization.
5, manufacture method according to claim 4 is characterized in that: the described extraction at dynamic vacuum extracted the condition of concentrating and is in the concentration tank: steam 0.10~0.15MPa, vacuum-0.06,70~80 ℃ of temperature.
CNA2006100018053A 2006-01-20 2006-01-20 Nutrition oral liquor Pending CN1840000A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104888008A (en) * 2015-06-11 2015-09-09 张家港市五湖新材料技术开发有限公司 Anti-fatigue drug combination and preparation method thereof
CN107616404A (en) * 2017-10-10 2018-01-23 广西金诚双丰农牧科技有限公司 The preparation method of health food containing bamboo rat skin
CN107668688A (en) * 2017-08-31 2018-02-09 湖南东健药业有限公司 A kind of preparation method of high grade of transparency donkey-hide gelatin
CN109452642A (en) * 2018-12-14 2019-03-12 王毅兴 Non- medicinal donkey-hide gelatin nutrient liquor of one kind and its preparation method and application

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104888008A (en) * 2015-06-11 2015-09-09 张家港市五湖新材料技术开发有限公司 Anti-fatigue drug combination and preparation method thereof
CN107668688A (en) * 2017-08-31 2018-02-09 湖南东健药业有限公司 A kind of preparation method of high grade of transparency donkey-hide gelatin
CN107616404A (en) * 2017-10-10 2018-01-23 广西金诚双丰农牧科技有限公司 The preparation method of health food containing bamboo rat skin
CN109452642A (en) * 2018-12-14 2019-03-12 王毅兴 Non- medicinal donkey-hide gelatin nutrient liquor of one kind and its preparation method and application
CN109452642B (en) * 2018-12-14 2022-01-11 王毅兴 Non-medicinal donkey-hide gelatin nutrient solution and preparation method and application thereof

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Open date: 20061004