CN1832941A - 作为抗菌剂的卤代喹唑啉基硝基呋喃类化合物 - Google Patents

作为抗菌剂的卤代喹唑啉基硝基呋喃类化合物 Download PDF

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Publication number
CN1832941A
CN1832941A CNA2004800228169A CN200480022816A CN1832941A CN 1832941 A CN1832941 A CN 1832941A CN A2004800228169 A CNA2004800228169 A CN A2004800228169A CN 200480022816 A CN200480022816 A CN 200480022816A CN 1832941 A CN1832941 A CN 1832941A
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CN
China
Prior art keywords
compound
general formula
nitro
furyl
fluoro
Prior art date
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Pending
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CNA2004800228169A
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English (en)
Chinese (zh)
Inventor
S·钱伯兰
F·马卢宁
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Ulysses Pharmaceutical Products Inc
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Ulysses Pharmaceutical Products Inc
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Filing date
Publication date
Application filed by Ulysses Pharmaceutical Products Inc filed Critical Ulysses Pharmaceutical Products Inc
Publication of CN1832941A publication Critical patent/CN1832941A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNA2004800228169A 2003-08-08 2004-08-06 作为抗菌剂的卤代喹唑啉基硝基呋喃类化合物 Pending CN1832941A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49333603P 2003-08-08 2003-08-08
US60/493,336 2003-08-08

Publications (1)

Publication Number Publication Date
CN1832941A true CN1832941A (zh) 2006-09-13

Family

ID=34135234

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800228169A Pending CN1832941A (zh) 2003-08-08 2004-08-06 作为抗菌剂的卤代喹唑啉基硝基呋喃类化合物

Country Status (9)

Country Link
US (1) US7410974B2 (https=)
EP (1) EP1660486A4 (https=)
JP (1) JP2007501809A (https=)
CN (1) CN1832941A (https=)
AU (1) AU2004262533A1 (https=)
BR (1) BRPI0413372A (https=)
CA (1) CA2534405A1 (https=)
MX (1) MXPA06001552A (https=)
WO (1) WO2005014585A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105796564A (zh) * 2016-04-12 2016-07-27 李春 一种防治牙体牙髓感染的药物组合物
CN108558854A (zh) * 2017-06-10 2018-09-21 曹艳 一种治疗革兰氏阳性菌引起的感染的药物及其合成方法
CN108690012A (zh) * 2017-06-10 2018-10-23 曹艳 一种治疗革兰氏阳性菌引起的感染的药物及其合成方法

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US20010016646A1 (en) * 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US20080146562A1 (en) * 2003-08-08 2008-06-19 Ulysses Pharmaceutical Products Inc., Halogenated quinazolinyl nitrofurans as antibacterial agents
EP1660486A4 (en) 2003-08-08 2006-12-13 Ulysses Pharmaceutical Product HALOGENATED CHINAZOLINYL NITROFURANES AS ANTIBACTERIAL AGENTS
CN101027299A (zh) * 2004-09-23 2007-08-29 尤利塞斯药品公司 碳－和杂－环硝基呋喃抗生素及其应用
EP1996732A4 (en) * 2006-03-02 2010-03-31 Uab Research Foundation RECOGNITION AND TREATMENT AND DISCOVERY OF REMEDIES AGAINST MYCOBACTERIAL DISEASES
US20080051422A1 (en) * 2006-08-22 2008-02-28 Concert Pharmaceuticals Inc. 4-Aminoquinazoline derivatives and methods of use thereof
US20110053964A1 (en) * 2006-08-22 2011-03-03 Roger Tung 4-aminoquinazoline derivatives and methods of use thereof
WO2008113161A1 (en) * 2007-03-19 2008-09-25 Ulysses Pharmaceutical Products Inc. Phosphate prodrugs of quinazolinyl nitrofurans, methods of obtaining, and use of same
ES2703253T3 (es) 2010-03-30 2019-03-07 Helperby Therapeutics Ltd Nueva combinación y uso
GB201013207D0 (en) 2010-08-05 2010-09-22 Helperby Therapeutics Ltd Novel combination
DK2600869T3 (da) 2010-08-05 2020-11-16 Helperby Therapeutics Ltd Kombination af en pyrroloquinolinforbindelse og et beta-lactam-antimikrobielt middel, mupirocin eller chlorhexidin
GB201015079D0 (en) 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
GB201305277D0 (en) 2013-03-22 2013-05-01 Helperby Therapeutics Ltd Novel combination and use
GB201307989D0 (en) 2013-05-02 2013-06-12 Helperby Therapeutics Ltd Novel combinations and use
GB201401617D0 (en) 2014-01-30 2014-03-19 Helperby Therapeutics Ltd Novel combination and use
HUE052575T2 (hu) 2014-12-18 2021-05-28 Helperby Therapeutics Ltd Új kombináció és alkalmazás
HK1250679A1 (zh) 2015-04-11 2019-01-11 Helperby Therapeutics Limited 口腔用组合物
GB201518969D0 (en) 2015-10-27 2015-12-09 Helperby Therapeutics Ltd Triple combination
GB201610869D0 (en) 2016-06-22 2016-08-03 Helperby Therapeutics Ltd Combination
GB201612093D0 (en) 2016-07-12 2016-08-24 Helperby Therapeutics Ltd Combination
GB201616014D0 (en) 2016-09-20 2016-11-02 Helperby Therapeutics Ltd Combination
GB201616909D0 (en) 2016-10-05 2016-11-16 Helperby Therapeutics Ltd Combination
GB201703898D0 (en) 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
GB201704620D0 (en) 2017-03-23 2017-05-10 Helperby Therapeautics Ltd Combinations
GB201709193D0 (en) 2017-06-09 2017-07-26 Helperby Therapeutics Ltd Combination
GB201807046D0 (en) 2018-04-30 2018-06-13 Helperby Therapeutics Ltd Combination
GB201913068D0 (en) 2019-09-10 2019-10-23 Helperby Therapeutics Ltd Combination
GB201914847D0 (en) 2019-10-14 2019-11-27 Helperby Therapeutics Ltd Combination
GB202213750D0 (en) 2022-09-20 2022-11-02 Helperby Therapeutics Ltd Antimicrobial
GB202213753D0 (en) 2022-09-20 2022-11-02 Helperby Therapeutics Ltd Antimicrobial combinations
GB202314387D0 (en) 2023-09-20 2023-11-01 Helperby Therapeutics Ltd Antimicrobial combinations

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DE2140280A1 (de) 1970-08-12 1972-02-17 Chemische Fabrik von Heyden GmbH, 8000 München 4 Amino 2 eckige Klammer auf 2 (5 Nitro 2 furyl)vinyl eckige Klammer zu chinazolinderivate, Herstellungsver fahren dafür und Arzneimittel daraus
US3973021A (en) * 1974-09-06 1976-08-03 Diamond Shamrock Corporation 2-[2-(5-Nitro-2-furyl)vinyl]-4-(phydroxyanilino)quinazoline as a bactericide
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105796564A (zh) * 2016-04-12 2016-07-27 李春 一种防治牙体牙髓感染的药物组合物
CN108558854A (zh) * 2017-06-10 2018-09-21 曹艳 一种治疗革兰氏阳性菌引起的感染的药物及其合成方法
CN108690012A (zh) * 2017-06-10 2018-10-23 曹艳 一种治疗革兰氏阳性菌引起的感染的药物及其合成方法

Also Published As

Publication number Publication date
AU2004262533A1 (en) 2005-02-17
JP2007501809A (ja) 2007-02-01
EP1660486A1 (en) 2006-05-31
MXPA06001552A (es) 2006-09-04
US7410974B2 (en) 2008-08-12
WO2005014585A8 (en) 2005-09-09
BRPI0413372A (pt) 2006-10-17
CA2534405A1 (en) 2005-02-17
WO2005014585A1 (en) 2005-02-17
EP1660486A4 (en) 2006-12-13
US20060258693A1 (en) 2006-11-16

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C06 Publication
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SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication