CN1771066B - 适用于给药装置的剂量标度和驱动机构 - Google Patents

适用于给药装置的剂量标度和驱动机构 Download PDF

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Publication number
CN1771066B
CN1771066B CN2004800078104A CN200480007810A CN1771066B CN 1771066 B CN1771066 B CN 1771066B CN 2004800078104 A CN2004800078104 A CN 2004800078104A CN 200480007810 A CN200480007810 A CN 200480007810A CN 1771066 B CN1771066 B CN 1771066B
Authority
CN
China
Prior art keywords
sleeve
housing
dose dial
reset
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2004800078104A
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English (en)
Chinese (zh)
Other versions
CN1771066A (zh
Inventor
R·F·维齐
S·温珀尼
D·A·普伦普特里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
DCA Design International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DCA Design International Ltd filed Critical DCA Design International Ltd
Publication of CN1771066A publication Critical patent/CN1771066A/zh
Application granted granted Critical
Publication of CN1771066B publication Critical patent/CN1771066B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN2004800078104A 2003-03-22 2004-03-22 适用于给药装置的剂量标度和驱动机构 Expired - Fee Related CN1771066B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0306642.0A GB0306642D0 (en) 2003-03-22 2003-03-22 Improvements in and relating to an injector for a medical product
GB0306642.0 2003-03-22
PCT/EP2004/002982 WO2004082748A1 (en) 2003-03-22 2004-03-22 Dose dial and drive mechanism suitable for use in drug delivery devices

Publications (2)

Publication Number Publication Date
CN1771066A CN1771066A (zh) 2006-05-10
CN1771066B true CN1771066B (zh) 2010-05-26

Family

ID=9955334

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800078104A Expired - Fee Related CN1771066B (zh) 2003-03-22 2004-03-22 适用于给药装置的剂量标度和驱动机构

Country Status (17)

Country Link
US (1) US7090662B2 (enExample)
EP (1) EP1610847B1 (enExample)
JP (1) JP5001001B2 (enExample)
KR (1) KR101124194B1 (enExample)
CN (1) CN1771066B (enExample)
AR (1) AR043743A1 (enExample)
BR (1) BRPI0408637B8 (enExample)
CA (1) CA2519846C (enExample)
DK (1) DK1610847T3 (enExample)
EA (1) EA007763B1 (enExample)
GB (1) GB0306642D0 (enExample)
HR (1) HRP20050839A2 (enExample)
IL (1) IL170993A (enExample)
MX (1) MXPA05010061A (enExample)
TW (1) TWI322016B (enExample)
WO (1) WO2004082748A1 (enExample)
ZA (1) ZA200507397B (enExample)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA56256C2 (uk) 1998-01-30 2003-05-15 Ново Нордіск А/С Шприц для ін'єкцій
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
AU2003209095A1 (en) 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
GB0222731D0 (en) * 2002-10-01 2002-11-06 Parker David W Improvements in or relating to hypodermic syringes
EP2210634A1 (en) 2009-01-22 2010-07-28 Sanofi-Aventis Deutschland GmbH Drug delivery device dose setting mechanism
GB0304822D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0308267D0 (en) * 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
FR2854878B1 (fr) 2003-05-15 2006-03-31 Valois Sas Distributeur de produit fluide.
JP5089991B2 (ja) * 2004-02-18 2012-12-05 アレス トレイディング ソシエテ アノニム 液状薬剤を注射する手持ち型電子制御式注射器械
PL1804865T3 (pl) 2004-10-21 2010-03-31 Novo Nordisk As Mechanizm wkręcania dla nawijanych penów
DK1850892T4 (da) 2005-01-24 2023-06-06 Antares Pharma Inc Forfyldt nål-assisteret sprøjtejetinjektor
US20080208142A1 (en) * 2005-02-28 2008-08-28 Novo Nordisk A/S Dose Setting Mechanism for an Injection Device
US20090043264A1 (en) 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
WO2006114395A1 (en) * 2005-04-24 2006-11-02 Novo Nordisk A/S An injection device with a gearbox
GB0524604D0 (en) 2005-12-02 2006-01-11 Owen Mumford Ltd Injection method and apparatus
GB2434103B (en) 2006-01-12 2009-11-25 Owen Mumford Ltd Lancet firing device
DE102006004561A1 (de) * 2006-01-17 2007-07-26 Tecpharma Licensing Ag Injektionsvorrichtung mit gesichertem Drehknopf
US8361036B2 (en) 2006-03-10 2013-01-29 Novo Nordisk A/S Injection device having a gearing arrangement
JP5062768B2 (ja) 2006-03-10 2012-10-31 ノボ・ノルデイスク・エー/エス 注射装置および該装置のカートリッジを交換する方法
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US8226618B2 (en) 2006-05-16 2012-07-24 Novo Nordisk A/S Gearing mechanism for an injection device
AU2007253481B2 (en) 2006-05-18 2013-01-17 Novo Nordisk A/S An injection device with mode locking means
AU2008213084B2 (en) 2007-02-05 2013-03-28 Novo Nordisk A/S Injection button
CA2681023C (en) 2007-03-23 2015-11-03 Novo Nordisk A/S An injection device comprising a locking nut
US8992484B2 (en) 2008-01-23 2015-03-31 Novo Nordisk A/S Device for injecting apportioned doses of liquid drug
US8814834B2 (en) 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
EP2274029B1 (en) 2008-05-02 2011-11-02 Sanofi-Aventis Deutschland GmbH Medication delivery device
US8187233B2 (en) * 2008-05-02 2012-05-29 Sanofi-Aventis Deutschland Gmbh Medication delivery device
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
MY153758A (en) * 2009-01-06 2015-03-13 Proteus Digital Health Inc Pharmaceutical dosages delivery system
DK2414005T3 (en) * 2009-04-03 2017-09-11 Shl Group Ab Drug delivery device
US8672896B2 (en) 2009-06-01 2014-03-18 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
US10034982B2 (en) * 2009-06-01 2018-07-31 Sanofi-Aventis Deutschland Gmbh Spindle for a drug delivery device
CA2767663C (en) * 2009-07-10 2017-10-31 Becton, Dickinson And Company Flush syringe assembly with controlled pulsatile flushing
EP2475411B1 (en) * 2009-09-07 2014-12-31 Sanofi-Aventis Deutschland GmbH Drive mechanism for drug delivery device
EP2292286A1 (en) * 2009-09-07 2011-03-09 Sanofi-Aventis Deutschland GmbH Drive mechanism for a medication delivery device and medication delivery device
AR078457A1 (es) * 2009-09-30 2011-11-09 Sanofi Aventis Deutschland Mecanismo accionador para un dispositivo de descarga de farmacos
EP2482889B1 (en) * 2009-09-30 2016-02-10 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device
BR112012007310A2 (pt) * 2009-09-30 2016-04-19 Sanofi Aventis Deutschland mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento
WO2011039205A2 (en) * 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Drug delivery device and drive member for a drug delivery device
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
ES2574057T3 (es) * 2009-12-15 2016-06-14 Shl Group Ab Dispositivo de administración de medicamento
EP2675498A4 (en) * 2011-02-19 2017-11-01 Touche Medical Ltd. Compact medical pump device
WO2012130704A1 (en) * 2011-03-25 2012-10-04 Sanofi-Aventis Deutschland Gmbh Drug delivery device
TWI574708B (zh) * 2011-06-17 2017-03-21 賽諾菲阿凡提斯德意志有限公司 用於藥物遞送裝置的卡匣支撐器總成
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
EP2797650A2 (en) 2011-12-29 2014-11-05 Novo Nordisk A/S Torsion-spring based wind-up autoinjector pen with dial-up/dial-down dosing mechanism
DE202012001411U1 (de) * 2012-02-10 2013-05-13 Haselmeier Gmbh Injektionsgerät
KR20150003179A (ko) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 분리력 특징을 가진 사전충전형 주사기
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
US9149585B2 (en) 2012-04-20 2015-10-06 Cook Medical Technologies Llc Multi-needle injection device
WO2013169804A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
DE202014001135U1 (de) 2014-02-05 2015-05-06 Haselmeier Gmbh Injektionsgerät
DE202015006845U1 (de) * 2015-09-30 2016-01-15 Haselmeier Ag Injektionsgerät
EP3474820B1 (en) 2017-08-24 2024-02-07 Novo Nordisk A/S Glp-1 compositions and uses thereof
US11083847B2 (en) 2018-01-26 2021-08-10 Becton, Dickinson And Company Flush syringe with flip cap
PE20230819A1 (es) 2020-02-18 2023-05-19 Novo Nordisk As Composiciones y usos de glp-1

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865591A (en) * 1987-06-12 1989-09-12 Hypoguard (Uk) Limited Measured dose dispensing device
CN1099301A (zh) * 1993-03-15 1995-03-01 伊莱利利公司 一种给药器械及使用方法
US6106501A (en) * 1995-11-09 2000-08-22 Disetronic Licensing Ag Injection device
CN1277558A (zh) * 1998-01-30 2000-12-20 诺沃挪第克公司 注射器
US6364860B1 (en) * 1997-06-05 2002-04-02 Disetronic Licensing Ag Resettable display of a device for metered administration of a fluid drug

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111731A1 (de) * 1981-03-25 1982-10-14 Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt Mikrowellenuebertragungseinrichtung mit mehrmodendiversity-kombinationsempfang
DK177187A (da) * 1987-04-07 1988-10-08 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glasampul
DE3715258C2 (de) * 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
DE3814023A1 (de) 1987-07-13 1989-01-26 Medizin Labortechnik Veb K Injektionsvorrichtung mit medikamentendepot
GB9007113D0 (en) 1990-03-29 1990-05-30 Sams Bernard Dispensing device
DE4112259A1 (de) * 1991-04-15 1992-10-22 Medico Dev Investment Co Injektionsgeraet
DE59202070D1 (de) * 1991-07-24 1995-06-08 Medico Dev Investment Co Injektor.
DK175491D0 (da) * 1991-10-18 1991-10-18 Novo Nordisk As Apparat
DK194291D0 (da) * 1991-11-29 1991-11-29 Novo Nordisk As Sproejte til automatisk injektion.
US5279586A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Reusable medication delivery pen
US5584815A (en) * 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
GB9503969D0 (en) * 1995-02-28 1995-04-19 Sams Bernard Incrementing mechanism
AU696439B2 (en) * 1995-03-07 1998-09-10 Eli Lilly And Company Recyclable medication dispensing device
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5957896A (en) * 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US6248095B1 (en) * 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
US6936032B1 (en) * 1999-08-05 2005-08-30 Becton, Dickinson And Company Medication delivery pen
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
US6899699B2 (en) * 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865591A (en) * 1987-06-12 1989-09-12 Hypoguard (Uk) Limited Measured dose dispensing device
CN1099301A (zh) * 1993-03-15 1995-03-01 伊莱利利公司 一种给药器械及使用方法
US6106501A (en) * 1995-11-09 2000-08-22 Disetronic Licensing Ag Injection device
US6364860B1 (en) * 1997-06-05 2002-04-02 Disetronic Licensing Ag Resettable display of a device for metered administration of a fluid drug
CN1277558A (zh) * 1998-01-30 2000-12-20 诺沃挪第克公司 注射器

Also Published As

Publication number Publication date
EA007763B1 (ru) 2006-12-29
EA200501507A1 (ru) 2006-04-28
GB0306642D0 (en) 2003-04-30
HRP20050839A2 (en) 2006-11-30
CN1771066A (zh) 2006-05-10
IL170993A (en) 2012-02-29
KR101124194B1 (ko) 2012-03-27
TWI322016B (en) 2010-03-21
US7090662B2 (en) 2006-08-15
CA2519846C (en) 2011-11-22
JP2006520627A (ja) 2006-09-14
DK1610847T3 (en) 2018-03-19
AR043743A1 (es) 2005-08-10
CA2519846A1 (en) 2004-09-30
ZA200507397B (en) 2007-02-28
BRPI0408637B1 (pt) 2015-12-22
US20040249348A1 (en) 2004-12-09
BRPI0408637B8 (pt) 2021-06-22
BRPI0408637A (pt) 2006-03-28
HK1091762A1 (zh) 2007-01-26
JP5001001B2 (ja) 2012-08-15
EP1610847A1 (en) 2006-01-04
MXPA05010061A (es) 2005-11-23
EP1610847B1 (en) 2017-12-13
TW200502020A (en) 2005-01-16
AU2004222587A1 (en) 2004-09-30
KR20060015713A (ko) 2006-02-20
WO2004082748A1 (en) 2004-09-30

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