CN1742762A - New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer - Google Patents

New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer Download PDF

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Publication number
CN1742762A
CN1742762A CN 200510029845 CN200510029845A CN1742762A CN 1742762 A CN1742762 A CN 1742762A CN 200510029845 CN200510029845 CN 200510029845 CN 200510029845 A CN200510029845 A CN 200510029845A CN 1742762 A CN1742762 A CN 1742762A
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China
Prior art keywords
chinese medicinal
medicinal material
extract
preparation
filter
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Pending
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CN 200510029845
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Chinese (zh)
Inventor
吴朝阳
徐发红
黄经球
陈科茂
黄建荣
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TIANSHIKANG CHINESE MEDICINES CO Ltd JIANGXI
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TIANSHIKANG CHINESE MEDICINES CO Ltd JIANGXI
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Priority to CN 200510029845 priority Critical patent/CN1742762A/en
Publication of CN1742762A publication Critical patent/CN1742762A/en
Pending legal-status Critical Current

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Abstract

The present invention discloses a new application of Chinese medicinal material sarcandra twig and leaf for curing chronic gastritis and gastroduodenal ulcer. Said extract of sarcandra twig and leaf can be made into various dosage forms. Said invention also provides its preparation method and concrete steps.

Description

Herba Sarcandrae is used for the treatment of the new purposes of chronic gastritis, gastric and duodenal ulcers
Technical field: the present invention relates to a kind of new purposes with glabrous sarcandra herb medical material, medicinal substances extract and preparation for treating chronic gastritis thereof, gastric and duodenal ulcers.
Background technology: Chinese medicinal material of sarcandra glaber is named Herba Pileae Scriptae, Ramulus Sambuci Williamsii, Herba Pileae Scriptae again, is the herb of Chloranthaceae plant plait Corallium Japonicum Kishinouye Sarcandra glabra (Thunb.) Nakai.Be renascent herb or undershrub, high 15~120cm, root manure is big, and stem is grown thickly, and joint is obviously.Its bitter in the mouth, suffering, property is flat, and is slightly poisonous.GUIXIN, Liver Channel.Have clearing away heat and cooling blood, the effect of the speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral, be used for heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury, tumors such as pneumonia, appendicitis, cellulitis, bacillary dysentery, abscess and digestive tract cancer, cancer of pancreas, hepatocarcinoma.Nearly several " Chinese pharmacopoeia is all recorded.Last century the seventies, former Jiangxi Province Guixi pharmaceutical factory (now belonging to Tianshikang Chinese Medicines Co., Ltd., Jiangxi) excavates and to have developed Herba Sarcandrae, successively it is developed into products such as ZHONGJIEFENG PIAN, injection, oral liquid.By discovering, Herba Sarcandrae contains effective active compositions such as phenols, flavonoid glycoside, coumarin, volatile oil, lactone, multiple pharmacological effect is arranged, but it is clinical to be applied to not entering as yet of chronic gastritis, gastric and duodenal ulcers treatment, does not see any report as yet with what its extract and preparation thereof were used for gastritis, gastric and duodenal ulcers.
Summary of the invention:
The purpose of this discovery is: a kind of new purposes of utilizing Chinese medicinal material of sarcandra glaber, medicinal substances extract and preparation thereof to be used for chronic gastritis, gastric and duodenal ulcers treatment is provided.
Herba Sarcandrae is by suppressing pepsic autologous tissue decomposition; direct and the gastric mucosa protein binding formation protecting film of energy promotes the reparation and the mucosa regeneration of ulcer, and kills helicobacter pylori activity; chronic gastritis, gastric and duodenal ulcers are had therapeutical effect preferably, and safety is good.
The Chinese medicinal material of sarcandra glaber, medicinal substances extract and the preparation thereof that are used for the treatment of chronic gastritis, gastric and duodenal ulcers can be realized by following any mode:
1, with the Chinese medicinal material of sarcandra glaber chopping, drying is pulverized, and sieves, and powder is directly made solid preparations such as powder, pill, tablet, capsule, granule.
2, Chinese medicinal material of sarcandra glaber is decocted with water, filter, filtrate is condensed into decoction and directly takes.
3, get Chinese medicinal material of sarcandra glaber, chopping was soaked 1 hour, and the decocting that adds to 10 times of amounts of medical material boils, and kept boiling 1 hour, filtered, and got decoction liquor, decocted altogether three times as method, and collecting decoction filters, and filtrate is condensed into the thick paste shape, is dried to dry extract.Get Herba Sarcandrae extract.Again Herba Sarcandrae extract is made the various dosage forms on the pharmaceutics book, as dosage forms such as granule, powder, tablet, capsule, pill, drop pill, oral liquid, syrup, mixture.
4, get Chinese medicinal material of sarcandra glaber, decoct with water secondary, each 2 hours, collecting decoction, filter, it is 1.33 (70 ℃ of surveys) that filtrate is concentrated into relative density, adds the ethanol precipitation secondary, make for the first time and contain the alcohol amount and reach 70%, make for the second time to contain the alcohol amount and reach 80%, each all cold preservation 48 hours filters, filtrate recycling ethanol also is concentrated into every 1ml and contains crude drug 10g, or with macroporous adsorbent resin or flocculation sediment technology, filter, regulate PH to 9, add activated carbon adsorption, decolouring is boiled, and filters, concentrate, get Herba Sarcandrae extract.Herba Sarcandrae extract is made all dosage forms on the pharmaceutics book.As dosage forms such as injection, drop pill, tablet, capsule, granule, pill, powder, oral liquid, syrup, mixture.

Claims (4)

1, a kind of Chinese medicinal material of sarcandra glaber, medicinal substances extract and preparation thereof are used for the treatment of the new purposes of chronic gastritis, gastric and duodenal ulcers.
2, a kind of as claims 1 described Chinese medicinal material of sarcandra glaber preparation, it is characterized in that with the Chinese medicinal material of sarcandra glaber chopping, drying is pulverized, and sieves, powder is directly made solid preparations such as powder, pill, tablet, capsule, granule.
3, a kind of as claims 1 described Herba Sarcandrae extract preparation method: as to get Chinese medicinal material of sarcandra glaber, chopping was soaked 1 hour, and the decocting that adds to 10 times of amounts of medical material boils, keep boiling 1 hour, filter, get decoction liquor, decoct altogether three times as method, collecting decoction, filter, filtrate is condensed into the thick paste shape, is dried to dry extract.Get Herba Sarcandrae extract.
4, a kind of as claims 1 described Herba Sarcandrae extract preparation method: as to get Chinese medicinal material of sarcandra glaber, decoct with water secondary, each 2 hours, collecting decoction, filter, it is 1.33 (70 ℃ of surveys) that filtrate is concentrated into relative density, adds the ethanol precipitation secondary, make for the first time and contain the alcohol amount and reach 70%, make for the second time to contain the alcohol amount and reach 80%, each all cold preservation 48 hours filters, filtrate recycling ethanol also is concentrated into every 1ml and contains crude drug 10g, or with macroporous adsorbent resin or flocculation sediment technical finesse, filter, regulate PH to 9, add activated carbon adsorption, decolouring is boiled, and filters, concentrate, get Herba Sarcandrae extract.
CN 200510029845 2005-09-19 2005-09-19 New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer Pending CN1742762A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200510029845 CN1742762A (en) 2005-09-19 2005-09-19 New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510029845 CN1742762A (en) 2005-09-19 2005-09-19 New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer

Publications (1)

Publication Number Publication Date
CN1742762A true CN1742762A (en) 2006-03-08

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Family Applications (1)

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CN 200510029845 Pending CN1742762A (en) 2005-09-19 2005-09-19 New use of Zhongjiefeng for treating chronic gastritis and stomach and duodenal ulcer

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CN (1) CN1742762A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103156940A (en) * 2013-01-16 2013-06-19 福建中医药大学 Formula composition and extraction process used for bone ache eliminating
CN112773823A (en) * 2021-01-29 2021-05-11 广西河丰药业有限责任公司 Preparation method of glabrous sarcandra herb extract and extract tablet

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103156940A (en) * 2013-01-16 2013-06-19 福建中医药大学 Formula composition and extraction process used for bone ache eliminating
CN103156940B (en) * 2013-01-16 2015-09-02 福建中医药大学 A kind of extracting technique of Chinese medicine for garden balsam stem pain-relieving
CN112773823A (en) * 2021-01-29 2021-05-11 广西河丰药业有限责任公司 Preparation method of glabrous sarcandra herb extract and extract tablet

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