CN1739547A - Acne treating ointment - Google Patents

Acne treating ointment Download PDF

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Publication number
CN1739547A
CN1739547A CN 200510106036 CN200510106036A CN1739547A CN 1739547 A CN1739547 A CN 1739547A CN 200510106036 CN200510106036 CN 200510106036 CN 200510106036 A CN200510106036 A CN 200510106036A CN 1739547 A CN1739547 A CN 1739547A
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China
Prior art keywords
comedo
chloromycetin
grams
acne
ointment
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Pending
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CN 200510106036
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Chinese (zh)
Inventor
颜福州
吴清亮
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Individual
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Individual
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Priority to CN 200510106036 priority Critical patent/CN1739547A/en
Publication of CN1739547A publication Critical patent/CN1739547A/en
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Abstract

The acne treating ointment has simple medicine composition, fast and high healing effect, less recurrence and less scar. The acne treating ointment consists of lincomycin and lidocaine 100 weight portions, chloromycetin 10-15 weight portions, and solvent 80-120 weight portions. Of the medicine material, lincomycin has broad bactericidal spectrum and high bactericidal activity on some bacteria inducing acne, chloromycetin has broad bactericidal spectrum on extracorporeal microbes, and lidocaine has pain relieving and itch stopping local narcosis effect, so that the acne treating ointment has fast and high acne healing effect.

Description

A kind of treatment comedo ointment
Technical field
The present invention relates to a kind of medicine that is used for the treatment of comedo.
Background technology
Comedo is a kind of dermatosis of common pilosity, especially teenager, and its sickness rate is higher.Though its pathogeny has the research report more, existing medicine is also of common occurrence, and certain curative effect, especially some Chinese medicine preparation and combination drug are much also arranged.But because not enough to the pathogeny understanding of comedo, most these type of medicines are cured the symptoms, not the disease so far, and effective percentage is higher, but cure rate is low, and it is many that recur after the drug withdrawal or healing back, can't effect a radical cure, concerning many teenager, become a kind of pertinacious disease, have a strong impact on its physical and mental health.Publication number comprises the effective ingredient of treatment of smallpox is made liquid for the patent application of CN1309960 provides a kind of compoistion and method of use for the treatment of comedo, is applied to or is sprayed on the affected part, covers common facial film then.The treatment of smallpox effective ingredient comprises biological preparation that all can external, Chinese medicine product, antibiotic, sulfa drugs, fungimycin, vitamin etc.The disperse medium of liquid comprises that water, ethanol and other can be used for the solvent of skin.Facial film is the known common facial film in this area.Publication number provides a kind of pharmaceutical composition for the treatment of comedo for the patent application of CN1557326, is drawn medicines such as quick, dexamethasone, isotretinoin, chloromycetin, vitamin E, vanishing cream to form by ethinylestradiol, bactrim, promethazine, horse Lay acid chlorobenzene.Publication number is that the patent application of CN1356106 discloses a kind of treatment comedo lotion and preparation method thereof, and this invention medicine is by ethanol, chloromycetin, metronidazole dry powder, VB#-[6], glycerol, salicylic acid, diethylstilbestrol, Calomelas, Cosan seven flavor medicine thing is prepared from.Publication number provides a kind of pharmaceutical composition for the treatment of comedo and preparation method thereof for the patent application of CN1235045.Contain Rhizoma Coptidis, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, artificial Calculus Bovis, cimetidine, chloromycetin, 5% nipalgin liquid and ethanol in the described pharmaceutical composition, during preparation, the good Chinese crude drug of available conventional method elder generation's infusion is ground into fine powder, promptly gets oral formulations with the cimetidine mix homogeneously; After getting catilan and being added in 70% ethanol dissolving, add nipalgin again, filter and fill up 70% ethanol in proportion in the rear filtrate and get final product.
Summary of the invention
The objective of the invention is at its cure rate of medicine of existing treatment comedo lower, cure the more problem of back recurrence, though it is simple to provide a kind of medicine to form, quick result, the treatment comedo ointment that cure rate is higher, the recurrence of healing back is less, cicatrix is less.
Material component of the present invention and be by the content of ratio of quality and the number of copies:
100 parts of lincomycin hydrochloride and lidocaine hydrochloride gels, 10~15 parts in chloromycetin, 80~120 parts of solvents.Said solvent is at least a in ethanol, glycerol, the propylene glycol etc.
Character of the present invention is the light green color unguentum, belongs to bentoquatam, and its indication is the treatment that is used for comedo, external, and its usage is a little medicine evenly to be embrocated the affected part, the lighter 1~2 time on the 1st, heavy person 2~3 times on the 1st after cleaning face.Preferably do not eat irritating food during the medication, drink pick-me-up less, do not smoke, guarantee enough sleeps, its curative effect is better.
When preparation the present invention said treatment comedo ointment, lincomycin hydrochloride and lidocaine hydrochloride gel and the chloromycetin ratio in above-mentioned content can be dissolved in the solvent.
Because the affected part of comedo mainly occurs in face, its secreting gland is many, is exposed to the external world again for a long time, very easily infects thalline, and especially the effect of teenager endocrine is vigorous, and therefore the treatment of comedo for a long time becomes the extremely difficult problem of people's concern.Compare with existing treatment comedo medicine, because in the contained raw material of the present invention, the antimicrobial spectrum of lincomycin is wider, and is higher to the antibacterial activity of some antibacterial, can suppress the synthetic of multiple bacterium protein, especially some thalline that brings out comedo be had higher antibiotic activeness.Chloromycetin is not only to typhoid fever, paratyphoid fever due to the sensitive strain, and the brain of aerobe and anaerobe mixed infection is dense swollen, and the various severe infections due to the serious anaerobic infection, rickettsial infection, sensitive bacterial etc. have good restraining and therapeutical effect; And be a kind of low bacterium property antimicrobial drug at external tool wide spectrum anti-microbial effect.Show through a large amount of clinical practices, the antibacterial action that utilizes the science compatibility of lincomycin and chloromycetin to be brought into play, mix an amount of external and have the local anesthetic lignocaine of pain relieving, itching-relieving action, make its instant effect of the said treatment comedo of the present invention ointment, the cure rate height is cured the back recurrence and is lacked, cicatrix is little, solve a difficult problem that perplexs numerous comedo patient, especially adolescent patients for a long time preferably, obtained unexpected therapeutic effect.Simultaneously, material component of the present invention is few, preparation technology is easy.
The specific embodiment
Following examples will further the present invention is further illustrated.
Embodiment 1
Lincomycin hydrochloride and lidocaine hydrochloride gel 100 grams and chloromycetin 10 grams are dissolved in etoh solvent 90 grams, obtain the light green color unguentum.
Embodiment 2
Similar with enforcement 1, its difference is that chloromycetin is 11 grams, and solvent is ethanol 45 grams, glycerol 35 grams and propylene glycol 40 grams.
Embodiment 3
Similar with enforcement 1, its difference is that chloromycetin is 12 grams, and solvent is ethanol 30 grams, glycerol 30 grams and propylene glycol 35 grams.
Embodiment 4
Similar with enforcement 1, its difference is that chloromycetin is 13 grams, and solvent is ethanol 60 grams and glycerol 40 grams.
Embodiment 5
Similar with enforcement 1, its difference is that chloromycetin is 14 grams, and solvent is glycerol 35 grams and propylene glycol 45 grams.
Embodiment 6
Similar with enforcement 1, its difference is that chloromycetin is 15 grams, and solvent is ethanol 45 grams, glycerol 35 grams and propylene glycol 25 grams.
Embodiment 7
500 milligrams of lincomycins, 400 milligrams of lignocaine and adjuvant 100 grams are mixed and made into lincomycin hydrochloride and lidocaine hydrochloride gel, and the adjuvant that is adopted can be selected ethacridine lactate, polyacrylic acid I, glycerol, ethanol, triethanolamine, oxybenzene second fat and purified water etc. for use.The lincomycin hydrochloride and lidocaine hydrochloride gel of gained and chloromycetin 10 grams are dissolved in etoh solvent 90 grams, obtain the light green color unguentum.
The character of above-mentioned prepared treatment comedo ointment is the light green color unguentum, belongs to bentoquatam, is used for the treatment of comedo, external, and its usage is a little medicine evenly to be embrocated the affected part, the lighter 1~2 time on the 1st, heavy person 2~3 times on the 1st after cleaning face.Preferably do not eat irritating food during the medication, drink pick-me-up less, do not smoke, guarantee enough sleeps, its curative effect is better.
Below provide some clinical examples.
1, the patient * * *, 21 years old now, the male, Anhai Town, Jinjiang City, Fujian Province Chang Houcai people from village, existing medical history more than 4 years, symptom is: face head has a lot of red and swollen shape comedos, oiliness.Once used commercially available multiple treatment comedo medicine, do not have obvious curative effects, have the minority product to use after, have some to alleviate, but administration time one is long or when discontinuing medication, recurrence again.In May, 2005, trial edition was invented said ointment, embrocated 2~3 times in every month, and after 1 week, the original red and swollen symptom of face obviously alleviates, and new affected part do not occur; After 2 weeks of medication, red and swollen affected part obviously diminishes, shoals; After 3 weeks of medication, redness disappears, and only stays cicatrix; After the medication 1 month, cicatrix is obviously thin out, dwindle, and comedo is eliminated fully.Adhere to after the recovery from illness that in one-month period repaste was wiped 1 time in per 2~3 days, so far not recurrence.The patient says happily: " you have given the youth, have given me sunlight! "
2, the patient * * *, 20 years old now, male, Anhai Town, Jinjiang City, Fujian Province Chang Houcai people from village, suffers from serious comedo from March, 2002, used multiple commercially available treatment comedo medicine, do not have obvious curative effects, because administration time is long, types of drugs is many, through hands extruding commonly used affected part, therefore when preparing trial edition and invent said ointment in February, 2005, positions such as whole forehead and cheek are red and swollen seriously, the pore chap.After 1 week of medication, red and swollen comedo obviously diminishes, and pore diminishes, and redness disappears; After 2 weeks of medication, new comedo do not occur, and the comedo of original redness becomes littler, cicatrix is thin out, and pore continues obviously to dwindle; After 3 weeks of medication, red and swollen comedo is almost all eliminated, and face only leaves light little cicatrix; After the medication 1 month, cicatrix is eliminated substantially.Adhere to every day later on or embrocate medicine 1 wheat harvesting period every other day on a small quantity, so far not recurrence.
3, the patient * * *, the man, people from Xi'an, Shaanxi now attends school college of law of Xiamen University, the junior begins illly from Senior Two, exhausted cosmetics and drug variety are various, therapeutic effect is unsatisfactory.Because face has many comedos, to be reluctant contact with the people, psychology begins to become and feels oneself inferior, and therefore disposition some irritability that also becomes often facing to mirror extruding comedo, also stays many cicatrixes on the face, squeezes and does variola initiation cyst.The patient uses the said treatment comedo of the present invention ointment, embrocates every day 3 times, after 1 week of medication, red and swollen symptom obviously disappears, and comedo dwindles, and continuous use is after 1 month, the comedo of patient face almost all disappears, and skin has recovered smooth and color and luster, because of the cicatrix that variola stays is also desalinated substantially.
4, the patient * * *, the woman, people from Xiamen, Fujian, 19 years old now, because of face belongs to oily skin, and be subjected to courses of infection, cover with comedo on the face, belong to the moderate patient, used many cosmetics and medicine on the market, also attempted herbal treatment, curative effect is all undesirable.The patient uses the said treatment comedo of the present invention ointment after 1 week, and face's situation has improvement greatly, and inflamed pimples all dwindles, and face's inflammation is eliminated substantially, loses simultaneously to grow new comedo.After 3 weeks of patient's medication, the preceding earlier pimples because of hands extruding redness is eliminated fully, and the cicatrix in affected part is thin out, and pore also presents the situation of dwindling, after 1 month, and face's recovery from illness.

Claims (2)

1, a kind of treatment comedo ointment is characterized in that its material component and by the content of ratio of quality and the number of copies is: 100 parts of lincomycin hydrochloride and lidocaine hydrochloride gels, 10~15 parts in chloromycetin, 80~120 parts of solvents.
2, a kind of treatment comedo ointment as claimed in claim 1 is characterized in that said solvent is at least a in ethanol, glycerol, the propylene glycol.
CN 200510106036 2005-09-20 2005-09-20 Acne treating ointment Pending CN1739547A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200510106036 CN1739547A (en) 2005-09-20 2005-09-20 Acne treating ointment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510106036 CN1739547A (en) 2005-09-20 2005-09-20 Acne treating ointment

Publications (1)

Publication Number Publication Date
CN1739547A true CN1739547A (en) 2006-03-01

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103479661A (en) * 2013-10-21 2014-01-01 刘彩群 Whitening, acne removal and freckle removal cosmetology medicine
CN106727534A (en) * 2017-01-09 2017-05-31 李瑶洁 A kind of Whelk-eliminating paste
CN110038022A (en) * 2019-05-29 2019-07-23 李燕 A kind of preparation method for the antiallergy spray being applicable in anti-acne

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103479661A (en) * 2013-10-21 2014-01-01 刘彩群 Whitening, acne removal and freckle removal cosmetology medicine
CN106727534A (en) * 2017-01-09 2017-05-31 李瑶洁 A kind of Whelk-eliminating paste
CN110038022A (en) * 2019-05-29 2019-07-23 李燕 A kind of preparation method for the antiallergy spray being applicable in anti-acne

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