CN102552734B - Gargle for treating dental ulcer - Google Patents
Gargle for treating dental ulcer Download PDFInfo
- Publication number
- CN102552734B CN102552734B CN201210049607XA CN201210049607A CN102552734B CN 102552734 B CN102552734 B CN 102552734B CN 201210049607X A CN201210049607X A CN 201210049607XA CN 201210049607 A CN201210049607 A CN 201210049607A CN 102552734 B CN102552734 B CN 102552734B
- Authority
- CN
- China
- Prior art keywords
- parts
- gargle
- chinese medicine
- ulcer
- weight portion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a gargle for treating dental ulcer, which is prepared by mixing 45-55 parts of carrot juice, 25-35 parts of fresh bamboo leaves juice, 80-120 parts of traditional Chinese medicine concentrated solution and 100-140 parts of deionized water by volume, wherein the traditional Chinese medicine concentrated solution takes 12-18 parts of honeysuckle, 13-17 parts of radix rehmanniae, 12-18 parts of radix scrophulariae, 12-18 parts of radix ophiopogonis and 3-7 parts of asarum by weight as raw medicines. The raw medicines are decocted and made into the traditional Chinese medicine concentrated solution; and each ml of solution comprises 0.8-1 mg of crude drugs. The gargle provided in the invention is capable of cleaning mouth, adjunctively treating dental ulcer, preventing relapse and achieving a health-care effect. The gargle can cover the shortage of cleaning water or normal saline and be used together with dental ulcer anoint or corresponding drugs, so that the gargle is safely used and has no untoward effect or toxic and side effects.
Description
Technical field
The present invention relates to a kind of collutory, particularly a kind of mouthwash for oral ulcer, with for the ulcer spot of rinsing the mouth, prevent and treat and the auxiliary treatment oral ulcer.
Background technology
The definite cause of disease of oral ulcer so far still can not be fully clear and definite, and what it has been generally acknowledged that oral ulcer is the result of many factors comprehensive function.Immunity, h and E may be " three factors " of oral ulcer morbidity, i.e. genetic background and suitable environmental factors (comprising spiritual neural body constitution, psychological behavior state, life and work and social environment etc.) but the immunoreation of exception throw and oral ulcer characteristic disease damage occurs.Also someone proposes " bigeminy factor " opinion, and extrinsic factor (virus and antibacterial) and endogenous inducement (variation of hormone, psychologic factors, malnutrition, systemic disease and immunologic function disorder) interact and cause a disease.
Existing Aphthasol thing mainly contains: the local antibacterial medicine is as Chlorhexidine Acetate Gargles, chlortetracycline ointment, gentamycin pad pasting etc.; Topical corticosteroid is as hydrocortisone medicine film, beclometasone gargarism or spray etc.; The local analgesia agent is as benzydamine gargarism or spray, local anesthesia gel etc.; Other local anti-inflammatory preparations are as sodium cromoglicate cough syrup, PGE2 glue etc.; Systemic administration is as prednisolone, miaow sulfur purine, levamisole, Colchicine etc.
Above medicine can produce therapeutic effect in various degree to oral ulcer, but also have untoward reaction and side effect in various degree, as irritant to oral mucosa as some medicine, the patient feels uncomfortable simultaneously, the side effect that also has some medicines can produce whole body such as be difficult for accepting.
In the therapeutic process of oral condition, usually all first adopt peace and quiet water or normal saline to gargle, oral cavity is kept clean, and then smear medicine, the diseases such as oral ulcer can be cured rapidly, avoided in oral cavity affected part unholiness and affect drug effect.But adopt peace and quiet water or normal saline to gargle, only can make oral cavity keep clean, function singleness, still lack the suitable collutory that can coordinate Drug therapy at present.
Summary of the invention
The purpose of this invention is to provide a kind of collutory for the treatment of oral ulcer, this collutory can make up the deficiency that peace and quiet water or normal saline are gargled, and coordinates oral ulcer to be coated with cream or corresponding drug use.
The collutory for the treatment of oral ulcer of the present invention is mixed and is made by 45～55 parts by volume Radix Dauci Sativae juices, the bright Folium Bambusae juice of 25～35 parts by volume, 80～120 parts by volume the concentrated liquid of tradition Chinese medicines and 100～140 parts by volume deionized waters.Wherein, described the concentrated liquid of tradition Chinese medicine is that to take 12～18 weight portion Flos Loniceraes, 13～17 weight portion Radix Rehmanniae, 12～18 weight portion Radix Scrophulariae, 12～18 weight portion Radix Ophiopogonis, 3～7 weight portion Herba Asaris be crude drug, and every ml that water boiling concentration is made is containing the concentrated liquid of tradition Chinese medicine of crude drug 0.8～1mg.
The collutory for the treatment of oral ulcer provided by the invention has cleaning oral cavity, auxiliary treatment oral ulcer, the effect that prevention is had a relapse and kept healthy.Collutory of the present invention can make up the deficiency that peace and quiet water or normal saline are gargled, and effect clean and sterilization is played in the ulcer affected part of rinsing the mouth before using medicine, simultaneously, can also coordinate oral ulcer to be coated with cream or relative medicine, makes medicine bring into play better drug effect.Collutory of the present invention is used safe and effective, and any untoward reaction or toxic and side effects do not occur.
Clinical trial:
Oral ulcer patient's 60 examples, average course of disease two days, clinical manifestation be take the local red and swollen and center ulcer of oral mucosa, erosion, pain as main, recurrent oral ulceration 47 examples wherein, traumatic ulcer 8 examples, other 5 examples, all patients except oral ulcer without other oral mucosa pathological changes, without medication history, without serious systemic disease.60 routine patients are divided into mouthwash for oral ulcer treatment group and watermelon crystal treatment group at random, every group of each 30 examples, treatment group male's 13 examples, women's 17 examples, 17～56 years old age; Matched group male 14 examples, women's 16 examples, 21～60 years old age.The equal not statistically significant of clinical manifestation difference (P>0.05) before the sex of two groups, age, the course of disease, treatment, have comparability.
Before treatment, advise the patient to gargle, keep oral hygiene.The mouthwash for oral ulcer treatment group adopts mouthwash for oral ulcer to be sprayed on affected part, every day 3～4 times; The watermelon crystal treatment group adopts watermelon crystal spray (Sanjin Pharmaceutical Co., Ltd., Guilin) to be sprayed on affected part, and every day 3～4 times, two groups of equal routines are taken vitamin C, vitamin B
2deng medicine, observe and compare two groups and treat rear affected part contrafluxion, edema, pain and ulcer healing situations.
The standard of curative effect evaluation: produce effects: medication after 3 days the office redness go down, without pain symptom, ulcer healing.Effectively: 1 week rear ulcer of medication heals substantially, without pain symptom.Invalid: surpass and still have pain in 1 week, ulcer is without improvement.Total effective rate=(produce effects+effectively)/total number of cases * 100%.Statistical procedures: two groups of efficient X 2 test, inspection level α=0.05 of relatively adopting.
Mouthwash for oral ulcer treatment group produce effects 22 examples, effective 8 examples, total effective rate is 100%; Watermelon crystal treatment group produce effects 17 examples, effective 7 examples, invalid 6 examples, total effective rate is 80%.Mouthwash for oral ulcer treatment group total effective rate is apparently higher than watermelon crystal treatment group (P<0.01).
The specific embodiment
Embodiment 1
Extracting honeysuckle 12 grams, the Radix Rehmanniae 17 grams, Radix Scrophulariae 18 grams, Radix Ophiopogonis 12 gram, Herba Asari 7 grams, add in 1.5 liters of deionized waters, first at 180 ℃, decocts 15 minutes, then decoct 30 minutes in 120 ℃, filters and obtain approximately 500 milliliters of filtrates.Add 1.5 liters of deionized waters in medicinal residues, 180 ℃ decoct 15 minutes again, and 120 ℃ decoct 30 minutes, filter and obtain approximately 300 milliliters of filtrates.Merge filtrate twice, 120 ℃ are concentrated into 120 milliliters, make the concentrated liquid of tradition Chinese medicine, and every ml is containing crude drug 0.8～1mg.
Get 600 KEHU Radix Raphani, cook after cleaning, squeeze out about 45 milliliters of Radix Dauci Sativae juices, wherein content beta-carotene is 0.14～0.24mg/ml.
Get 45 milliliters of Radix Dauci Sativae juices, 80 milliliters of the concentrated liquid of tradition Chinese medicines, bright Folium Bambusae juice 35 milliliters of (Folium Bambosae flavone content is 0.25～0.35 mg/ml) and 110 ml deionized water, mix, be mixed with mouthwash for oral ulcer.
This collutory is brown liquid, lightly seasoned sweet.Be preferably at ordinary times sooner or later and use between two meal, suck 20～30 milliliters of collutory, retain 5～10 minutes in oral cavity, spue after gargling.For infant or the person that can gargle voluntarily, avoid using as far as possible.
Embodiment 2
Extracting honeysuckle 15 grams, the Radix Rehmanniae 15 grams, Radix Scrophulariae 15 grams, Radix Ophiopogonis 15 gram, Herba Asari 5 grams, add in 1.5 liters of deionized waters, first at 180 ℃, decocts 15 minutes, then decoct 30 minutes in 120 ℃, filters and obtain approximately 500 milliliters of filtrates.Add 1.5 liters of deionized waters in medicinal residues, 180 ℃ decoct 15 minutes again, and 120 ℃ decoct 30 minutes, filter and obtain approximately 300 milliliters of filtrates.Merge filtrate twice, 120 ℃ are concentrated into 120 milliliters, make the concentrated liquid of tradition Chinese medicine, and every ml is containing crude drug 0.8～1mg.
Get 600 KEHU Radix Raphani, cook after cleaning, squeeze out about 50 milliliters of Radix Dauci Sativae juices, then add 100 milliliters of the concentrated liquid of tradition Chinese medicines, 30 milliliters, bright Folium Bambusae juice and 120 ml deionized water, mix, be mixed with mouthwash for oral ulcer.
Claims (1)
1. a collutory for the treatment of oral ulcer, be to be mixed and to be made by 45～55 parts by volume Radix Dauci Sativae juices, the bright Folium Bambusae juice of 25～35 parts by volume, 80～120 parts by volume the concentrated liquid of tradition Chinese medicines and 100～140 parts by volume deionized waters; Wherein, described the concentrated liquid of tradition Chinese medicine is that to take 12～18 weight portion Flos Loniceraes, 13～17 weight portion Radix Rehmanniae, 12～18 weight portion Radix Scrophulariae, 12～18 weight portion Radix Ophiopogonis, 3～7 weight portion Herba Asaris be crude drug, and every ml that water boiling concentration is made is containing the concentrated liquid of tradition Chinese medicine of crude drug 0.8～1mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210049607XA CN102552734B (en) | 2012-02-29 | 2012-02-29 | Gargle for treating dental ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210049607XA CN102552734B (en) | 2012-02-29 | 2012-02-29 | Gargle for treating dental ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102552734A CN102552734A (en) | 2012-07-11 |
| CN102552734B true CN102552734B (en) | 2013-12-11 |
Family
ID=46400188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210049607XA Expired - Fee Related CN102552734B (en) | 2012-02-29 | 2012-02-29 | Gargle for treating dental ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102552734B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748516A (en) * | 2016-03-30 | 2016-07-13 | 黄宇松 | Pharmaceutical composition for treating repeated oral ulcers |
| CN106620612A (en) * | 2016-12-24 | 2017-05-10 | 李大兴 | Traditional Chinese medicine gargle |
| CN108498721A (en) * | 2017-02-28 | 2018-09-07 | 北京智诚拓展广告传媒有限公司 | A kind of fresh leaf of bamboo nanometer juice and its preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554361A (en) * | 2008-04-11 | 2009-10-14 | 崔守尧 | Mouthwash for oral ulcer |
-
2012
- 2012-02-29 CN CN201210049607XA patent/CN102552734B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554361A (en) * | 2008-04-11 | 2009-10-14 | 崔守尧 | Mouthwash for oral ulcer |
Non-Patent Citations (2)
| Title |
|---|
| 增液释邪法治疗复发性口腔溃疡53例;张海红;《实用中医内科杂志》;20070205(第01期);78-79 * |
| 张海红.增液释邪法治疗复发性口腔溃疡53例.《实用中医内科杂志》.2007,(第01期), |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102552734A (en) | 2012-07-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101732558A (en) | Traditional Chinese medicine granules used for treating chronic pharyngitis | |
| CN101632750B (en) | Chinese medicinal composition for replenishing essence, filling marrow, boosting kidney and strengthening yang and preparation method thereof | |
| CN102552734B (en) | Gargle for treating dental ulcer | |
| CN106511161A (en) | Traditional Chinese herbal medicine toothpaste with treatment effect on canker sore | |
| CN108379139A (en) | A kind of toothpaste and its preparation method and application of anti-treating dental ulcer | |
| CN102657785B (en) | Medicinal composition for treating gingivitis | |
| CN105213353B (en) | Compound oral film and preparation method containing sodium azulenesulfonate | |
| CN101732500A (en) | Medicine for preventing and treating acute and chronic pharyngitis and sphagitis | |
| CN104548029A (en) | Pharmaceutical composition for treating epigastric pain | |
| CN100563677C (en) | A kind of moistening and cleaning throat Chinese medicine preparation | |
| CN102743587A (en) | External application wound repair liquid | |
| CN102600343A (en) | Chinese medicinal preparation for treating oral diseases and/or toothache | |
| CN100577199C (en) | Application of stomachic pill with cyperus and amomum | |
| CN1277573C (en) | Medication for curing ulcerationd of oral cavity | |
| CN114949147B (en) | Traditional Chinese medicine composition for treating chronic pharyngitis and preparation method and application thereof | |
| CN114432359B (en) | Traditional Chinese medicine gargle, preparation method and application thereof in preparation of medicine for treating oral ulcer | |
| CN112933122B (en) | Traditional Chinese medicine external medicine for treating recurrent oral ulcer | |
| CN100560118C (en) | A kind of Chinese medicine preparation for the treatment of recurrent oral ulceration | |
| CN1159028C (en) | Chinese medicine for treating various hemorrhagic diseases caused by reduced prothrombin | |
| CN101612203A (en) | A kind of Chinese medicine composition and application thereof that is used for the treatment of condyloma acuminatum | |
| CN1164283C (en) | Pulmonotis treating Chinese medicine powder | |
| CN105381433A (en) | Traditional Chinese medicine oral caring and refreshing agent | |
| CN117482201A (en) | Traditional Chinese medicine composition for preventing and treating rhinitis as well as preparation method and application thereof | |
| CN116549520A (en) | Qi-blood tonifying, lung heat clearing and cough relieving traditional Chinese medicine formula, traditional Chinese medicine liquid and traditional Chinese medicine preparation | |
| CN103550373B (en) | Medicament for treating gingivitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131211 Termination date: 20210228 |