CN106511161A - Traditional Chinese herbal medicine toothpaste with treatment effect on canker sore - Google Patents
Traditional Chinese herbal medicine toothpaste with treatment effect on canker sore Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses traditional Chinese herbal medicine toothpaste with a treatment effect on canker sore. The traditional Chinese herbal medicine toothpaste consists of a toothpaste body substrate and traditional Chinese herbal medicine extracts, wherein the traditional Chinese herbal medicine extracts account for 3 to 6 percent, and the rest is the toothpaste body substrate; and the traditional Chinese herbal medicine extracts are prepared from the following active pharmaceutical ingredients including 35 to 45g of honeysuckle flowers, 35 to 45g of begonia roots, 25 to 35g of fructus forsythiae, 25 to 35g of spica prunellae, 15 to 25g of amomum tsao-ko, 15 to 20g of mulberry leaves, 35 to 45g of gnaphalium affine, 20 to 30g of eriosema himalaicum ohashi, 5 to 15g of serissa japonica, 15 to 25g of radix sileris, 15 to 25g of fructus corni and 5 to 15g of dried orange peel. The traditional Chinese herbal medicine toothpaste with the treatment effect on canker sore has the effects of clearing away heat and toxic materials, promoting the circulation of qi to stop bleeding, relieving swelling and pain, clearing away the heat to diminish swelling, invigorating the blood circulation, strengthening the teeth and the like, and can be used for effectively preventing and treating the canker sore.
Description
Technical field
The present invention relates to a kind of Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer.
Background technology
Toothpaste, is the material for teeth surfaces.Toothpaste is the cleaning supplies commonly used in daily life.At present, with
The continuous development of science and technology, technological equipment is updated and perfect, and various types of toothpaste are come out one after another, the matter of product
Amount and class are improved constantly, and present toothpaste variety develops into great variety of goods, function many by single clean type toothpaste
Sample, the Mobyneb toothpaste of up to a hundred brands, meets the needs of different levels level of consumption.
Oral cavity is gastral start-up portion.Front excuse is split and is communicated with the external world, by isthmus faucium with pharynx continuously.Have in oral cavity
The organs such as tooth, tongue.The antetheca in oral cavity is lip, side wall is cheek, top is palate, oral cavity bottom is the structure such as mucosa and flesh.Borrow upper and lower in oral cavity
Dental arch is divided into the oral cavity proper of the vestibule of mouth of front lateral part and rear medial part；When maxillary and mandibular teeth is engaged, vestibule of mouth with it is solid
Have between oral cavity and the gap at third molar rear can be borrowed to communicate.Due to diet, cleaning custom etc., most people are suffering from different journeys
The oral disease of degree.Oral ulcer, is also called " aphtha ", is the superficial ulcer occurred on oral mucosa, and big I is from rice
, to Semen Glyciness size, circular or oval, ulcer surface is congested for recessed, surrounding for grain.Ulcer has periodicity, recurrent and self limiting
The features such as, it is apt to occur in lip, cheek, lingual margin etc..The cause of disease and mechanism of causing a disease are still indefinite.Inducement be probably local wound, psychentonia,
Food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism are at which
May play an important role in generation, development.Mainly based on local treatment, severe patient needs whole body therapeutic for treatment.
In prior art, the Chinese medicine preparation of existing various treatment oral ulcer, but curative effect is not good enough mostly, after healing easily
Recurrence.
The content of the invention
For above-mentioned prior art, the invention provides a kind of Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer, its
Containing medicinal herb componentses, can anti-treating dental ulcer comprehensively, therapeutic effect significantly, while safe, has no side effect, after healing not
Easily recur.
The present invention is achieved by the following technical solutions：
A kind of Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer, by lotion of toothpaste substrate and Chinese herbal medicine extract group
Into wherein, Chinese herbal medicine extract accounts for 3～6% (preferably 5%) (percetages by weight), balance of lotion of toothpaste substrate；The medium-height grass
Medicament extract is by made by following crude drug：35～45 grams of Flos Lonicerae, 35～45 grams of Radix Bischofiae Javanicae, 25～35 grams of Fructus Forsythiae, summer
25～35 grams of hay, 15～25 grams of Fructus Tsaoko, 15～20 grams of Folium Mori, 35～45 grams of Herba Gnaphalii Affinis, 20～30 grams of Eriosema himalaicum Ohashi, Serissa foetida 5
～15 grams, 15～25 grams of Radix Saposhnikoviae, 15～25 grams of Fructus Corni, 5～15 grams of Pericarpium Citri Reticulatae.
Preferably, the Chinese herbal medicine extract is by made by following crude drug：40 grams of Flos Lonicerae, 40 grams of Radix Bischofiae Javanicae,
30 grams of Fructus Forsythiae, 30 grams of Spica Prunellae, 20 grams of Fructus Tsaoko, 18 grams of Folium Mori, 40 grams of Herba Gnaphalii Affinis, 25 grams of Eriosema himalaicum Ohashi, 10 grams of Serissa foetida, Radix Saposhnikoviae 20
Gram, 20 grams of Fructus Corni, 10 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 55%～65%
(percentage by volume) ethanol solution reflux, extract, solid-liquid ratio is 1:5～7 (mass volume ratio, units g：Ml), 90 DEG C of Extracting temperature
± 3 DEG C, 5～7 hours extraction times, extracting solution is obtained, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
The Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer of the present invention, containing Radix Bischofiae Javanicae, Spica Prunellae, Radix Saposhnikoviae, Mulberry
The effective ingredient of leaf, Herba Gnaphalii Affinis etc., by reasonable compatibility, with heat-clearing and toxic substances removing, circulation of qi promoting hemostasis, reducing swelling and alleviating pain, detumescence of relieving inflammation or internal heat, work
The effects such as blood teeth consolidating, can effectively anti-treating dental ulcer, herpes of mouth, oral cavity get angry, oral mucosa irritation, etc. oral disease, especially
Which is oral ulcer.
Specific embodiment
With reference to embodiment, the present invention is further illustrated.
Embodiment 1 prepares Chinese herbal toothpaste
It is made up of lotion of toothpaste substrate and Chinese herbal medicine extract, wherein, Chinese herbal medicine extract accounts for 5%, balance of toothpaste cream
Body substrate；The Chinese herbal medicine extract is by made by following crude drug：40 grams of Flos Lonicerae, 40 grams of Radix Bischofiae Javanicae, 30 grams of Fructus Forsythiae,
30 grams of Spica Prunellae, 20 grams of Fructus Tsaoko, 18 grams of Folium Mori, 40 grams of Herba Gnaphalii Affinis, 25 grams of Eriosema himalaicum Ohashi, 10 grams of Serissa foetida, 20 grams of Radix Saposhnikoviae, Fructus Corni
20 grams, 10 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 60% (volume
Percent) ethanol solution reflux, extract, solid-liquid ratio is 1:6 (mass volume ratio, units g：Ml), 90 DEG C of Extracting temperature, during extraction
Between 6 hours, obtain extracting solution, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
Embodiment 2 prepares Chinese herbal toothpaste
It is made up of lotion of toothpaste substrate and Chinese herbal medicine extract, wherein, Chinese herbal medicine extract accounts for 3%, balance of toothpaste cream
Body substrate；The Chinese herbal medicine extract is by made by following crude drug：35 grams of Flos Lonicerae, 45 grams of Radix Bischofiae Javanicae, 25 grams of Fructus Forsythiae,
35 grams of Spica Prunellae, 15 grams of Fructus Tsaoko, 20 grams of Folium Mori, 35 grams of Herba Gnaphalii Affinis, 30 grams of Eriosema himalaicum Ohashi, 5 grams of Serissa foetida, 25 grams of Radix Saposhnikoviae, Fructus Corni
15 grams, 15 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 65% (volume
Percent) ethanol solution reflux, extract, solid-liquid ratio is 1:5 (mass volume ratio, units g：Ml), 90 DEG C ± 3 DEG C of Extracting temperature, carry
Take the time 6 hours, obtain extracting solution, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
Embodiment 3 prepares Chinese herbal toothpaste
It is made up of lotion of toothpaste substrate and Chinese herbal medicine extract, wherein, Chinese herbal medicine extract accounts for 4%, balance of toothpaste cream
Body substrate；The Chinese herbal medicine extract is by made by following crude drug：45 grams of Flos Lonicerae, 35 grams of Radix Bischofiae Javanicae, 35 grams of Fructus Forsythiae,
25 grams of Spica Prunellae, 25 grams of Fructus Tsaoko, 15 grams of Folium Mori, 45 grams of Herba Gnaphalii Affinis, 20 grams of Eriosema himalaicum Ohashi, 15 grams of Serissa foetida, 15 grams of Radix Saposhnikoviae, Fructus Corni
25 grams, 5 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 60% (volume
Percent) ethanol solution reflux, extract, solid-liquid ratio is 1:7 (mass volume ratio, units g：Ml), 90 DEG C ± 3 DEG C of Extracting temperature, carry
Take the time 6 hours, obtain extracting solution, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
Embodiment 4 prepares Chinese herbal toothpaste
It is made up of lotion of toothpaste substrate and Chinese herbal medicine extract, wherein, Chinese herbal medicine extract accounts for 5%, balance of toothpaste cream
Body substrate；The Chinese herbal medicine extract is by made by following crude drug：38 grams of Flos Lonicerae, 38 grams of Radix Bischofiae Javanicae, 32 grams of Fructus Forsythiae,
32 grams of Spica Prunellae, 18 grams of Fructus Tsaoko, 18 grams of Folium Mori, 32 grams of Herba Gnaphalii Affinis, 22 grams of Eriosema himalaicum Ohashi, 12 grams of Serissa foetida, 22 grams of Radix Saposhnikoviae, Fructus Corni
18 grams, 13 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 58% (volume
Percent) ethanol solution reflux, extract, solid-liquid ratio is 1:6 (mass volume ratio, units g：Ml), 90 DEG C ± 3 DEG C of Extracting temperature, carry
Take the time 5 hours, obtain extracting solution, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
Embodiment 5 prepares Chinese herbal toothpaste
It is made up of lotion of toothpaste substrate and Chinese herbal medicine extract, wherein, Chinese herbal medicine extract accounts for 6%, balance of toothpaste cream
Body substrate；The Chinese herbal medicine extract is by made by following crude drug：42 grams of Flos Lonicerae, 42 grams of Radix Bischofiae Javanicae, 28 grams of Fructus Forsythiae,
28 grams of Spica Prunellae, 22 grams of Fructus Tsaoko, 20 grams of Folium Mori, 42 grams of Herba Gnaphalii Affinis, 27 grams of Eriosema himalaicum Ohashi, 8 grams of Serissa foetida, 18 grams of Radix Saposhnikoviae, Fructus Corni
22 grams, 6 grams of Pericarpium Citri Reticulatae.
The Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, with 55% (volume
Percent) ethanol solution reflux, extract, solid-liquid ratio is 1:6 (mass volume ratio, units g：Ml), 90 DEG C ± 3 DEG C of Extracting temperature, carry
Take the time 7 hours, obtain extracting solution, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
The preparation method of the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer is：Chinese herbal medicine extract is added to
In lotion of toothpaste substrate, mix, obtain final product.
The Chinese herbal toothpaste of above-mentioned preparation, it is sooner or later each using once daily, oral cavity bacterium can be killed comprehensively, effectively prevent and treat mouth
The oral diseases such as chamber ulcer, herpes of mouth, oral cavity are got angry, oral mucosa irritation.Specifically used example effects are as follows：
The patient with oral ulcer is selected to be applied, patient totally 214,15～45 years old age, man 112, female 102
Example.
The Chinese herbal toothpaste that all patients are prepared using above-described embodiment 1 is brushed teeth, sooner or later respectively once daily, without which
Its medicine.After using 2 weeks, observe and evaluate curative effect.
The standard of curative effect evaluation：
Cure：Symptom disappears or basic disappearance.
Effectively：Symptom is most of to take a turn for the better.
It is invalid：Effective standard or exacerbation of symptoms person are not reached.
As a result：After 2 weeks, in 214 oral ulcer patients, cure 191, effective 19, invalid 4.
All user are without obvious side effect.All healing persons, recidivist 5 in three months.
Conclusion：The toothpaste of the present invention, has good prevention effect, has no side effect, control difficulty in relapse after healing to oral ulcer.
Representative instance 1：Korea Spro so-and-so, man, 33 years old, like eating meat, have oral ulcer, and (early morning is especially tight with halitosis
Weight), can not be alleviated using ordinary toothpaste.The toothpaste prepared using embodiment 1 is brushed teeth, and the daily morning and evening was each once, using 1 week
Afterwards, symptom is considerably reduced, and oral ulcer is cured, and the gas abnormal flavour of exhalation is considerably reduced, is continuing with one week, the gas base of exhalation
This free from extraneous odour, effect is significant.
Representative instance 2：It is bent certain, female, 28 years old, Jing often got angry, oral ulcer, deep disturbed.The tooth prepared using embodiment 1
Cream is brushed teeth, and the daily morning and evening is each once, and after 3 days, oral ulcer recovery from illness is continuing with 10 days.Pay a return visit after three months, there are no
Oral ulcer recurs, effect is significant.
Claims (3)
1. a kind of Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer, it is characterised in that：By lotion of toothpaste substrate and Chinese herbal medicine
Extract is constituted, and wherein, Chinese herbal medicine extract accounts for 3～6%, balance of lotion of toothpaste substrate；The Chinese herbal medicine extract be by
Made by following crude drug：35～45 grams of Flos Lonicerae, 35～45 grams of Radix Bischofiae Javanicae, 25～35 grams of Fructus Forsythiae, 25～35 grams of Spica Prunellae,
15～25 grams of Fructus Tsaoko, 15～20 grams of Folium Mori, 35～45 grams of Herba Gnaphalii Affinis, 20～30 grams of Eriosema himalaicum Ohashi, 5～15 grams of Serissa foetida, Radix Saposhnikoviae 15
～25 grams, 15～25 grams of Fructus Corni, 5～15 grams of Pericarpium Citri Reticulatae.
2. the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer according to claim 1, it is characterised in that：The medium-height grass
Medicament extract is by made by following crude drug：40 grams of Flos Lonicerae, 40 grams of Radix Bischofiae Javanicae, 30 grams of Fructus Forsythiae, 30 grams of Spica Prunellae, Fructus Tsaoko
20 grams, 18 grams of Folium Mori, 40 grams of Herba Gnaphalii Affinis, 25 grams of Eriosema himalaicum Ohashi, 10 grams of Serissa foetida, 20 grams of Radix Saposhnikoviae, 20 grams of Fructus Corni, 10 grams of Pericarpium Citri Reticulatae.
3. the Chinese herbal toothpaste for having therapeutic efficiency to oral ulcer according to claim 1 and 2, it is characterised in that：It is described
Chinese herbal medicine extract is prepared by the following method and obtains：Each crude drug is taken, is mixed, flowed back with 55%～65% ethanol solution
Extract, solid-liquid ratio is 1:5～7 (mass volume ratio, units g：Ml), 90 DEG C ± 3 DEG C of Extracting temperature, 5～7 hours extraction times,
Extracting solution is obtained, concentrating under reduced pressure, drying obtain final product Chinese herbal medicine extract.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468624A (en) * | 2017-10-18 | 2017-12-15 | 桂林大创科技有限公司 | A kind of toothpaste with hemostasis shield gum and preparation method thereof |
| CN108403543A (en) * | 2018-03-22 | 2018-08-17 | 湖南三五二环保科技有限公司 | A kind of prevention acute toothache Chinese herbal toothpaste |
| CN108403586A (en) * | 2018-04-18 | 2018-08-17 | 佛山科学技术学院 | A kind of medicinal essential oil toothpaste and preparation method thereof |
| CN113491647A (en) * | 2020-04-03 | 2021-10-12 | 中国热带农业科学院农产品加工研究所 | Zanthoxylum bungeanum pain-relieving and inflammation-diminishing toothpaste and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784933A (en) * | 2014-03-07 | 2014-05-14 | 王爱文 | Recurrent oral ulcer power |
| CN104069333A (en) * | 2014-06-27 | 2014-10-01 | 王文英 | Medicine for treating recurrent oral ulceration and preparation method thereof |
| CN105193688A (en) * | 2015-10-07 | 2015-12-30 | 梅照付 | Toothpaste for removing bad breath |
-
2016
- 2016-11-16 CN CN201611017302.5A patent/CN106511161A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784933A (en) * | 2014-03-07 | 2014-05-14 | 王爱文 | Recurrent oral ulcer power |
| CN104069333A (en) * | 2014-06-27 | 2014-10-01 | 王文英 | Medicine for treating recurrent oral ulceration and preparation method thereof |
| CN105193688A (en) * | 2015-10-07 | 2015-12-30 | 梅照付 | Toothpaste for removing bad breath |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468624A (en) * | 2017-10-18 | 2017-12-15 | 桂林大创科技有限公司 | A kind of toothpaste with hemostasis shield gum and preparation method thereof |
| CN108403543A (en) * | 2018-03-22 | 2018-08-17 | 湖南三五二环保科技有限公司 | A kind of prevention acute toothache Chinese herbal toothpaste |
| CN108403586A (en) * | 2018-04-18 | 2018-08-17 | 佛山科学技术学院 | A kind of medicinal essential oil toothpaste and preparation method thereof |
| CN113491647A (en) * | 2020-04-03 | 2021-10-12 | 中国热带农业科学院农产品加工研究所 | Zanthoxylum bungeanum pain-relieving and inflammation-diminishing toothpaste and preparation method thereof |
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Application publication date: 20170322 |