CN1709434A - Chinese medicine formulation for treating sphagitis - Google Patents
Chinese medicine formulation for treating sphagitis Download PDFInfo
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- CN1709434A CN1709434A CN 200510080549 CN200510080549A CN1709434A CN 1709434 A CN1709434 A CN 1709434A CN 200510080549 CN200510080549 CN 200510080549 CN 200510080549 A CN200510080549 A CN 200510080549A CN 1709434 A CN1709434 A CN 1709434A
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Abstract
The present invention relates to a Chinese medicine preparation for curing pharyngolaryngeal diseases of acute pharyngitis, chronic pharyngitis, tonsillitis and others with obvious therapeutic effect. Said Chinese medicine preparation can be made into soluble granules or pill preparation, and can be made up by using 14 Chinese medicinal materials of bushy sophora root, platycodon root, belamcanda root, moutan root bark, silkworm and others through a certain preparation process.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, the Chinese medicine preparation of the treatment pharyngolaryngitis of particularly a kind of tool heat-clearing and toxic substances removing, anti-inflammatory analgetic, removing the necrotic tissue and promoting granulation.
Background technology
Pharyngeal is one of human body more complicated, important organ, pharyngitis and tonsillitis are the higher diseases of sickness rate, it accounts for second of whole body sickness rate, because China is very large in area and thickly populated, among economy is developing, present many disease of pharynx can't in time obtain medical treatment, so exploitation is more, more efficient, the pharyngitis medicine of low toxicity, to be fit to the needs of Economic Development and people ' s health.
In view of this, in order to address the above problem, this creator is according to oneself clinical experience and medical science theory, after deliberation, test, and has the present invention to produce eventually.
Summary of the invention
The present invention will provide a kind of Chinese medicine preparation for the treatment of pharyngolaryngitis, with solution make its tool heat-clearing and toxic substances removing, dispelling wind and eliminating swelling, anti-inflammatory analgetic, act as expectorant, removing the necrotic tissue and promoting granulation, reach the technical problem of laryngopharyngeal diseasess such as treatment acute/chronic pharyngitis, tonsillitis, throat moth.
It is such solving the problems of the technologies described above the technical scheme that is adopted:
A kind of Chinese medicine preparation for the treatment of pharyngolaryngitis is characterized in that: it is made by following raw materials in weight portion:
7～10 parts of 6～9 parts of Cortex Moutans of 8～11 parts of Rhizoma Belamcandae of 6～9 parts of Radix Platycodoniss of Radix Sophorae Tonkinensis
6～9 parts of 6～9 parts of Flos Chrysanthemi of 7～10 parts of Radix Saposhnikoviaes of 6～10 portions of Herba Schizonepetae of Bombyx Batryticatus
10～15 parts of 10～15 parts of Fructus Forsythiaes of 10～18 parts of Radix Rehmanniae of 3～6 portions of Radix Scrophulariaes of Herba Menthae
6～9 parts in 6～10 portions of Radix Glycyrrhizaes of Semen Oroxyli.
It is made by following optimum weight part proportion raw material:
8 parts of 9 parts of Bombyx Batryticatus of 7 parts of Cortex Moutans of 10 parts of Rhizoma Belamcandae of 8 parts of Radix Platycodoniss of Radix Sophorae Tonkinensis
15 parts of 4 portions of Radix Scrophulariaes of 8 portions of Herba Menthaes of 8 parts of Flos Chrysanthemi of 9 parts of Radix Saposhnikoviaes of Herba Schizonepetae
7 parts in 8 portions of Radix Glycyrrhizaes of 12 portions of Semen Oroxylis of 12 parts of Fructus Forsythiaes of the Radix Rehmanniae.
This medicament is a said dosage form on any pharmaceutics; This medicament is electuary or pill.
The preparation method of this electuary is:
(1) steam distillation takes by weighing Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Herba Menthae four Chinese medicine material by described formulation weight part proportioning and proposes wherein volatile oil and Mentholum composition with steam distillation, and the aqueous solution after the distillation is collected in addition, and its medicinal residues reuse decocting boils;
(2) preparation of decocting liquid I, above-mentioned four Chinese medicine slag is taken by weighing Semen Oroxyli again with by described formulation weight part proportioning, Cortex Moutan, Bombyx Batryticatus, Radix Platycodonis, Rhizoma Belamcandae, Radix Sophorae Tonkinensis, Flos Chrysanthemi seven flavor medicine material decocts with water twice, add for the first time water and be 7～8 times of medical material weight, 1 hour time, add for the second time water and be 5～6 times of medical material weight, 40 minutes time, collecting decoction, filter, filtrate and above-mentioned aqueous solution merge, and carry out concentration, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add equal-volume ethanol and carry out precipitation process, left standstill 24 hours, get the supernatant concentrating under reduced pressure, be decocting liquid I;
(3) preparation of decocting liquid II takes by weighing the Radix Rehmanniae, Radix Scrophulariae, Radix Glycyrrhizae three flavor medical materials by described formulation weight part proportioning and decocts with water twice, adds water for the first time and be 7～8 times of medical material weight, half an hour time, add for the second time water and be 5～6 times of medical material weight, half an hour time, collecting decoction, filtration, filtrate is carried out concentration equally, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add the long-pending ethanol of triploid and carry out precipitation process, left standstill 24 hours, getting the supernatant concentrating under reduced pressure is decocting liquid II;
(4) clear paste preparation, collecting decoction I and decocting liquid II, being concentrated into relative density is 1.35～1.38g/cm
3Clear paste;
(5) preparation of granules adds sweeting agent and dextrin with above-mentioned clear paste, and its weight ratio is: 1 part of clear paste, and 0.04 part of sweeting agent, 2 parts in dextrin and 80% volume ethanol mix homogeneously are made granule, and are dried into dry granular;
(6) finished product adds volatile oil and the Mentholum that Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, the Herba Menthae four Chinese medicine of step (1) distill out with above-mentioned dry granular, and mix homogeneously promptly obtains finished product;
This electuary is a sepia, and it is sweet to distinguish the flavor of, little hardship; This electuary grain diameter is 0.2～1.0mm; This sweeting agent is sugar alcohol sweeting agent or natural sweetener.
The present invention is made by following raw materials according: Radix Sophorae Tonkinensis, Radix Platycodonis, Rhizoma Belamcandae, Cortex Moutan, Bombyx Batryticatus, Herba Schizonepetae, Radix Saposhnikoviae, Flos Chrysanthemi, Herba Menthae, Radix Scrophulariae, the Radix Rehmanniae, Fructus Forsythiae, Semen Oroxyli and Radix Glycyrrhizae, this medicament is electuary or pill, and the technological process of its electuary is: the preparation of the preparation of steam distillation → decocting liquid I → decocting liquid II → clear paste preparation → preparation of granules → finished product.Its preparation has significant heat-clearing and toxic substances removing, lung qi dispersing sore-throat relieving, effects such as anti-inflammatory analgesic, improved the curative effect for the treatment of acute and chronic pharyngolaryngitis, and non-toxic reaction, take safety, thereby solved and made its tool heat-clearing and toxic substances removing, dispelling wind and eliminating swelling, anti-inflammatory analgetic, acted as expectorant, removing the necrotic tissue and promoting granulation, reached the technical problem of laryngopharyngeal diseasess such as treatment acute/chronic pharyngitis, tonsillitis, throat moth.
Advantage of the present invention is as follows:
1, the present invention proves by pharmacological testing, has significant heat-clearing and toxic substances removing, lung qi dispersing sore-throat relieving, anti-inflammatory analgesic action, and comprehensive each medicine that utilizes share, and treating both the principal and secondary aspects of a disease, the exterior and the interior are laid equal stress on, heat is trembled with fear and transfer, and have improved pharmaceutical effectiveness.
2, the present invention shows non-toxic reaction by test, clinical dosage safety.
3, the present invention adopts modern crafts production and strict quality monitoring that production scale is enlarged, and is more suitable for the needs of current market economy, and the tool practicality.
Description of drawings
Fig. 1 is preparation technology's flow chart of the present invention.
The specific embodiment
The weight proportion of Chinese medicine preparation one embodiment of this treatment pharyngolaryngitis is:
Radix Sophorae Tonkinensis 8 gram Radix Platycodoniss 10 gram Rhizoma Belamcandae 7 gram Cortex Moutans 9 gram Bombyx Batryticatus 8 grams
Herba Schizonepetae 9 gram Radix Saposhnikoviaes 8 gram Flos Chrysanthemi 8 gram Herba Menthaes 4 gram Radix Scrophulariaes 15 grams
The Radix Rehmanniae 12 gram Fructus Forsythiaes 12 gram Semen Oroxylis 8 gram Radix Glycyrrhizaes 7 grams.
The Chinese medicine preparation of this treatment pharyngolaryngitis is electuary or pill, and the Example formulations of its electuary takes by weighing by above-mentioned formulation weight or multiple formulation weight:
As shown in Figure 1, be preparation technology's flow chart of the present invention, the step of this electuary preparation method is:
(1) steam distillation takes by weighing Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Herba Menthae four Chinese medicine material by described formulation weight proportioning and proposes wherein volatile oil and Mentholum composition with steam distillation, and the aqueous solution after the distillation is collected in addition, and its medicinal residues reuse decocting boils;
(2) preparation of decocting liquid I, above-mentioned four Chinese medicine slag is taken by weighing Semen Oroxyli again with by described formulation weight proportioning, Cortex Moutan, Bombyx Batryticatus, Radix Platycodonis, Rhizoma Belamcandae, Radix Sophorae Tonkinensis, Flos Chrysanthemi seven flavor medicine material decocts with water twice, add for the first time water and be 7～8 times of medical material weight, 1 hour time, add for the second time water and be 5～6 times of medical material weight, 40 minutes time, collecting decoction, filter, filtrate and above-mentioned aqueous solution merge, and carry out concentration, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add equal-volume ethanol and carry out precipitation process, left standstill 24 hours, get the supernatant concentrating under reduced pressure, be decocting liquid I;
(3) preparation of decocting liquid II takes by weighing the Radix Rehmanniae, Radix Scrophulariae, Radix Glycyrrhizae three flavor medical materials by described formulation weight proportioning and decocts with water twice, adds water for the first time and be 7～8 times of medical material weight, half an hour time, add for the second time water and be 5～6 times of medical material weight, half an hour time, collecting decoction, filtration, filtrate is carried out concentration equally, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add the long-pending ethanol of triploid and carry out precipitation process, left standstill 24 hours, getting the supernatant concentrating under reduced pressure is decocting liquid II;
(4) clear paste preparation, collecting decoction I and decocting liquid II, being concentrated into relative density is 1.35～1.38g/cm
3Clear paste;
(5) preparation of granules adds sweeting agent and dextrin with above-mentioned clear paste, and its weight ratio is: 1 part of clear paste, and 0.04 part of sweeting agent, 2 parts in dextrin and 80% volume ethanol mix homogeneously are made granule, and are dried into dry granular;
(6) finished product adds volatile oil and the Mentholum that Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, the Herba Menthae four Chinese medicine of step (1) distill out with above-mentioned dry granular, and mix homogeneously promptly obtains finished product;
This electuary is a sepia, and it is sweet to distinguish the flavor of, little hardship, and this electuary grain diameter is 0.2～1.0mm, this sweeting agent is sugar alcohol sweeting agent or natural sweetener.
This electuary treatment pharyngolaryngitis, the patient obeys electuary every day three times, each 15 grams, five days is a course of treatment, and acute pharyngolaryngitis is taken and is got final product a course of treatment, and chronic pharyngolaryngitis is taken 4～5 courses of treatment, and heavy pharyngolaryngitis patient takes 7～8 courses of treatment and can cure.With this electuary over hundreds of acute and chronic pharyngolaryngitis patients are carried out clinical trial, all reached the effect of curing fully.Please carry out acute toxicity test to this electuary in the Traditional Chinese Medicine Research Institute, Sichuan Province simultaneously, result of the test shows that this electuary clinical dosage is a safety non-toxic.
In sum, effect of the present invention has tangible lifting, has practicality, meets each important document of patent of invention, so propose application for a patent for invention in accordance with the law.
Claims (8)
1, a kind of Chinese medicine preparation for the treatment of pharyngolaryngitis, it is characterized in that: it is made by following raw materials in weight portion:
7～10 parts of 6～9 parts of Cortex Moutans of 8～11 parts of Rhizoma Belamcandae of 6～9 parts of Radix Platycodoniss of Radix Sophorae Tonkinensis
6～9 parts of 6～9 parts of Flos Chrysanthemi of 7～10 parts of Radix Saposhnikoviaes of 6～10 portions of Herba Schizonepetae of Bombyx Batryticatus
10～15 parts of 10～15 parts of Fructus Forsythiaes of 10～18 parts of Radix Rehmanniae of 3～6 portions of Radix Scrophulariaes of Herba Menthae
6～9 parts in 6～10 portions of Radix Glycyrrhizaes of Semen Oroxyli.
2, the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 1 is characterized in that: it is made by following optimum weight part proportion raw material:
8 parts of 9 parts of Bombyx Batryticatus of 7 parts of Cortex Moutans of 10 parts of Rhizoma Belamcandae of 8 parts of Radix Platycodoniss of Radix Sophorae Tonkinensis
15 parts of 4 portions of Radix Scrophulariaes of 8 portions of Herba Menthaes of 8 parts of Flos Chrysanthemi of 9 parts of Radix Saposhnikoviaes of Herba Schizonepetae
7 parts in 8 portions of Radix Glycyrrhizaes of 12 portions of Semen Oroxylis of 12 parts of Fructus Forsythiaes of the Radix Rehmanniae.
3, the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 1 and 2 is characterized in that: this medicament is a said dosage form on any pharmaceutics.
4, the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 3 is characterized in that: this medicament is electuary or pill.
5, the preparation method of the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 4 is characterized in that: the step of this electuary preparation method is:
(1) steam distillation takes by weighing Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Herba Menthae four Chinese medicine material by described formulation weight part proportioning and proposes wherein volatile oil and Mentholum composition with steam distillation, and the aqueous solution after the distillation is collected in addition, and its medicinal residues reuse decocting boils;
(2) preparation of decocting liquid I, above-mentioned four Chinese medicine slag is taken by weighing Semen Oroxyli again with by described formulation weight part proportioning, Cortex Moutan, Bombyx Batryticatus, Radix Platycodonis, Rhizoma Belamcandae, Radix Sophorae Tonkinensis, Flos Chrysanthemi seven flavor medicine material decocts with water twice, add for the first time water and be 7～8 times of medical material weight, 1 hour time, add for the second time water and be 5～6 times of medical material weight, 40 minutes time, collecting decoction, filter, filtrate and above-mentioned aqueous solution merge, and carry out concentration, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add equal-volume ethanol and carry out precipitation process, left standstill 24 hours, get the supernatant concentrating under reduced pressure, be decocting liquid I;
(3) preparation of decocting liquid II takes by weighing the Radix Rehmanniae, Radix Scrophulariae, Radix Glycyrrhizae three flavor medical materials by described formulation weight part proportioning and decocts with water twice, adds water for the first time and be 7～8 times of medical material weight, half an hour time, add for the second time water and be 5～6 times of medical material weight, half an hour time, collecting decoction, filtration, filtrate is carried out concentration equally, be concentrated into 1ml and be equivalent to 1g medical material amount, be cooled to room temperature, add the long-pending ethanol of triploid and carry out precipitation process, left standstill 24 hours, getting the supernatant concentrating under reduced pressure is decocting liquid II;
(4) clear paste preparation, collecting decoction I and decocting liquid II, being concentrated into relative density is 1.35～1.38g/cm
3Clear paste;
(5) preparation of granules adds sweeting agent and dextrin with above-mentioned clear paste, and its weight ratio is: 1 part of clear paste, and 0.04 part of sweeting agent, 2 parts in dextrin and 80% volume ethanol mix homogeneously are made granule, and are dried into dry granular;
(6) finished product adds volatile oil and the Mentholum that Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, the Herba Menthae four Chinese medicine of step (1) distill out with above-mentioned dry granular, and mix homogeneously gets product.
6, the preparation method of the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 5 is characterized in that: this electuary is a sepia, and it is sweet to distinguish the flavor of, little hardship.
7, the preparation method of the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 5 is characterized in that: this electuary grain diameter is 0.2～1.0mm.
8, the preparation method of the Chinese medicine preparation of treatment pharyngolaryngitis according to claim 5 is characterized in that: this sweeting agent is sugar alcohol sweeting agent or natural sweetener.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510080549 CN1709434A (en) | 2005-07-05 | 2005-07-05 | Chinese medicine formulation for treating sphagitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510080549 CN1709434A (en) | 2005-07-05 | 2005-07-05 | Chinese medicine formulation for treating sphagitis |
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|---|---|
| CN1709434A true CN1709434A (en) | 2005-12-21 |
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|---|---|---|---|
| CN 200510080549 Pending CN1709434A (en) | 2005-07-05 | 2005-07-05 | Chinese medicine formulation for treating sphagitis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100376274C (en) * | 2006-04-10 | 2008-03-26 | 庞来祥 | Medicinal composition used for treating pharyngitis, its prepn. method and its quality control method |
| CN102578291A (en) * | 2012-02-29 | 2012-07-18 | 万勤劳 | Health-care beancurd piece containing Chinese herbal formulations and production process thereof |
| CN104666844A (en) * | 2015-03-31 | 2015-06-03 | 佘延英 | Medicine for treating chronic pharyngolaryngitis |
-
2005
- 2005-07-05 CN CN 200510080549 patent/CN1709434A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100376274C (en) * | 2006-04-10 | 2008-03-26 | 庞来祥 | Medicinal composition used for treating pharyngitis, its prepn. method and its quality control method |
| CN102578291A (en) * | 2012-02-29 | 2012-07-18 | 万勤劳 | Health-care beancurd piece containing Chinese herbal formulations and production process thereof |
| CN104666844A (en) * | 2015-03-31 | 2015-06-03 | 佘延英 | Medicine for treating chronic pharyngolaryngitis |
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Open date: 20051221 |