CN1695704A - Compound capsule for relieving cough - Google Patents

Abstract

An antitussive Chinese medicine in the form of capsule for treating cough, pertussis, etc is prepared from 11 Chinese-medicinal materials including stemona root, mulberry bark, tangerine peel, liquorice root, etc.

Description

A kind of compound capsule for relieving cough

Technical field:

The present invention relates to medicinal preparation, specifically is to be the clearing away lung-heat to relieve cough medicine that raw material is mixed with by modern preparation process production with the Chinese herbal medicine.

Background technology:

Cough is a kind of protectiveness respiratory reflex action of human body.The generation of cough is because when the sensor in the stimulation respiratory mucosas such as foreign body, irritative gas, respiratory tract endocrine, impulsion is passed to the oblongata coughing centre by afferent nerve fiber, causes cough.

Cough also is the cardinal symptom of respiratory system disease, is dry cough seldom as cough but no phlegm or amount of expectoration, is common in acute pharyngolaryngitis, bronchitic initial stage; Foreign body in the bronchus is more common in the acute cough that takes place suddenly.And cough with copious phlegm expectorant thick sputum Huang mostly is the long-term chronic cough that chronic bronchitis, pulmonary tuberculosis etc. cause.

Cough is one of cardinal symptom of illness for lung, studies carefully its origin cause of formation not diseases caused by exogenous pathogenic factor, internal injury two ways.Or by the exopathogen invasion and attack, lung is defended and is felt, impairment of dispersing and descending function of the lung, thereby cough person is taken place; Or, reach lungs and be cough by other cacosplanchnia marks.

The exogenous cough mainly is because due to the heresy criminal lung of wind, cold, summer-heat, wet, dry, fiery six climate exopathogens.Wind, cold, summer-heat, wet, dry, fiery six gas all can cause and cough, but because the difference of climate change in 4 o'clock, the pathogenic exopathogen that human body is experienced is also had any different, thus wind and cold also will appear clinically, wind heat and different cough the such as scorching.Clinical findings is many with wind and cold.Wind being the primary exopathogen again so in all cards of exogenous cough, no matter because wind and cold, wind heat or scorching, how based on wind, press from both sides exopathogen such as cold, hot, dry and invade, is hindered in lung and is and is cough.Other also can be violated lung and cause and cough as sucking the foul gas of flue dust.

Lungs weakness, or he cause cough dirty ill involving in lung, all belong to the endogenous cough.

Last two kinds of coughs, the most common with the exogenous cough, and among the exogenous cough, the cough due to lung-heat who causes with the pathogenic heat invasion (based on the comparatively violent symptom such as lasting of the yellow thickness of cough expectorant, throat) is comparatively common again.

The method and the medicament categories of treatment cough are various, and doctor trained in Western medicine has aerosol therapy and the various maincenter antitussive medicine and the expelling phlegm drugs of antiinflammatory antiallergic, as carbetapentane citrate and compound Radix Glycyrrhizae mixture etc.And China's traditional Chinese medical science is particular about to the ill the treatment of cough and is comprehensive, and medicine is complicated and changeable especially, as Extractum Fel Serpentis et Bulbus Fritillariae Cirrhosae et Radix Saurauiae Tristylae, KEKE JIAONANG etc.But often there is the bigger problem of toxic and side effects in present Western medicine therapy; And the therapy of Chinese medicine, because also there is the restriction of curing object in the restriction of treatment principle and pharmic function.

Summary of the invention:

The objective of the invention is to produce the most common cough of a kind of treatment people-cough due to lung-heat's that the pathogenic heat invasion causes produce effects Chinese herbal and crude drugs preparations.

For reaching above purpose, the present invention is prepared into specially good effect cough suppressing medicine-compound stemona root cough relieving capsule with the Radix Stemonae, Radix Scutellariae, the Rhizoma Anemarrhenae, Cortex Mori, Radix Platycodonis, Semen Armeniacae Amarum, Radix Ophiopogonis, Rhizoma Arisaematis, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Glycyrrhizae by the modern pharmacy production technology.

The Radix Stemonae in the side, sweet in the mouth, hardship, slightly warm in nature has the effect of nourishing the lung to arrest cough.Radix Scutellariae, bitter in the mouth is cold in nature, and GUIXIN, lung, gallbladder, spleen, stomach, large intestine, small intestine meridian have the effect of clearing away heat-fire detoxifcation.Above-mentioned two flavors are the monarch drug in the side altogether.For strengthening the effect of clearing away lung-heat to relieve cough, add Cortex Mori, the Rhizoma Anemarrhenae in the side, two medicines share, and really can add the merit of monarch drug clearing away lung-heat to relieve cough, are the ministerial drug in the side altogether.Right cough due to lung-heat's card, the yellow thickness difficulty of its expectorant is coughed up.So Fang Zhongxu adds the product of the phlegm and relieving cough of entering an association,, be the adjuvant drug in the side altogether as Semen Armeniacae Amarum, Radix Platycodonis, Rhizoma Arisaematis, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Glycyrrhizae etc.

More than all medicines share, play the merit of clearing away lung-heat to relieve cough altogether.Be used for the lung-heat cough-relieving, the yellow thickness person of expectorant.Pertussis and demonstrate,proving see lung-heat syndrome marquis person also available it.

Each component of compound stemona root cough relieving capsule composition of the present invention is formulated by following parts by weight of raw materials: the Radix Stemonae 90～110, Semen Armeniacae Amarum 40～60, Radix Platycodonis 40～60, Cortex Mori 40～60, Radix Scutellariae 90～110, Rhizoma Arisaematis 20～30, Pericarpium Citri Reticulatae 90～110, Fructus Aurantii 40～60, Radix Ophiopogonis 20～30, the Rhizoma Anemarrhenae 20～30, Radix Glycyrrhizae 20～30.

Compound stemona root cough relieving capsule manufacture technology of the present invention is as follows:

Get the medical material under the product prescription item, decoct with water secondary, each 1～4 hour, merge decoction liquor, filter, the filtrate evaporation and concentration at drying under reduced pressure below 80 ℃, is pulverized when moisture≤3.0%, the cream powder is with 70%～80% alcohol granulation, film-coat is wrapped in oven dry below 60 ℃ or to be loaded in the capsule behind the barrier material enclose, exterior and interior packing gets product.

Compound stemona root cough relieving capsule of the present invention confirms that by anti-application and the observation that claims harbor district First People's Hospital of clinical unit's Guangxi Fangchenggang City it has the merit of clearing away lung-heat to relieve cough, is used for the cough due to lung-heat, the yellow thickness person of expectorant; Pertussis is demonstrate,proved and seen that the lung-heat patient also has good curative effect.Total effective rate is 98.3%, significantly is better than 57.7% of matched group ketelin capsule.

The specific embodiment:

Embodiment 1:

Getting the Radix Stemonae (sweet moxibustion) 100 gram, Semen Armeniacae Amarum 50 grams, Radix Platycodonis 50 grams, Cortex Mori 50 grams, Radix Scutellariae 100 grams, Rhizoma Arisaematis (system) 25 grams, Pericarpium Citri Reticulatae 100 grams, Fructus Aurantii (parched) 50 grams, Radix Ophiopogonis 25 gram, the Rhizoma Anemarrhenae 25 grams, Radix Glycyrrhizae 25 restrains.Decoct with water secondary jointly, 3 hours for the first time, 2 hours for the second time, merge decoction liquor, filter, the filtrate evaporation and concentration is to 1.20/80 ℃ of relative density, and drying under reduced pressure below 80 ℃ is pulverized when moisture≤3.0%, the cream powder is with 80% alcohol granulation, film-coat is wrapped in oven dry below 60 ℃ or to be loaded in the capsule behind the barrier material enclose, exterior and interior packing gets product.Make 3000 of capsules altogether, every is equivalent to crude drug 2 grams.

Compound stemona root cough relieving capsule of the present invention is used for the treatment of the cough due to lung-heat, the yellow thickness of expectorant, and pertussis and see the lung-heat patient, each 3～6, serve on 4 days at every day 2～3 times.

Claims (2)

1, a kind of compound capsule for relieving cough, it is characterized in that each component of compositions is formulated by following parts by weight of raw materials: the Radix Stemonae 90～110, Semen Armeniacae Amarum 40～60, Radix Platycodonis 40～60, Cortex Mori 40～60, Radix Scutellariae 90～110, Rhizoma Arisaematis 20～30, Pericarpium Citri Reticulatae 90～110, Fructus Aurantii 40～60, Radix Ophiopogonis 20～30, the Rhizoma Anemarrhenae 20～30, Radix Glycyrrhizae 20～30.

2, the preparation method of the described compound capsule for relieving cough of a kind of claim 1, it is characterized in that by the preparation of following production technology: get fully that medicine decocts with water secondary, each 1～4 hour, merge decoction liquor, filter, the filtrate evaporation and concentration at drying under reduced pressure below 80 ℃, is pulverized when moisture≤3.0%, the cream powder is with 70%～80% alcohol granulation, oven dry below 60 ℃, bag film-coat or with behind the barrier material enclose is loaded on it in capsule.