CN1686207A

CN1686207A - Ready prepared Chinese medicine for treating male sterility

Info

Publication number: CN1686207A
Application number: CNA2005100124838A
Authority: CN
Inventors: 胡春福
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-04-29
Filing date: 2005-04-29
Publication date: 2005-10-26
Anticipated expiration: 2025-04-29
Also published as: CN1686207B

Abstract

A Chinese patent medicine for treating male sterility is prepared from 18 Chinese-medicinal materials including ginseng, pilose antler, sea horse, wolfberry fruit, etc.

Description

A kind of Chinese patent medicine for the treatment of male infertility

Technical field

The present invention relates to the Chinese herbal medicine field of medicaments, particularly a kind of Chinese patent medicine for the treatment of male infertility.

Background technology

Male infertility is a kind of relatively disease of refractory, shows according to data at home and abroad: just have 15 pairs of patients with infertility among per 100 couples of Mr. and Mrs.Add up according to World Health Organization (WHO): ten thousand couples of Mr. and Mrs of global nearly 600-8000 suffer from infertility in various degree, and wherein reason accounts for 50% on the bridegroom's or husband's side.The Chinese population radix is big, relative incidence probability height, and through investigation, its main cause is: factors such as environmental pollution, bad life habits, cause man's sperm quality poor, cause generally descend human fertility.Simultaneously, the research masculine sterility also is the pith of family planning.The medicine technical field is accumulating comparatively rich experience aspect the treatment in China, many effective Chinese patent medicines are also arranged, for example support the beautiful soup of smart kind, the kidney invigorating seed side, pill for warming kidney etc., though these Chinese patent medicines are respectively having advantage aspect the treatment barrenness, all there is its limitation in every kind of medicine.

Summary of the invention

Purpose of the present invention just is to provide a kind of man's of raising life quality, can accelerate man's sperm and form, and improves the Chinese patent medicine of the treatment male infertility of fertility.

The present invention seeks to realize by following technical solution:

A kind of Chinese patent medicine for the treatment of male infertility, its medicament of forming by the following weight proportion raw material (gram): Radix Ginseng 6-20 Cornu Cervi Pantotrichum 10-20 Hippocampus 10-30 Radix Morindae Officinalis 6-30 Fructus Schisandrae Chinensis 10-30 Fructus Lycii 60-200 Fructus Ligustri Lucidi 10-20 field dobber 100-200 Fructus Rosae Laevigatae 10-20 Fructus Rubi 10-40 Semen Plantaginis 10-30 Radix Angelicae Sinensis 10-30 Radix Rehmanniae 10-30 Herba Cistanches 10-30 Herba Epimedii 20-100 Fructus Cnidii 10-30 Semen Allii Tuberosi 10-30 Fructus Toosendan 10-30.

The preparation method of a kind of routine of above-mentioned medicament is: 1, above-mentioned each herbal medicine raw material is weighed up in proportion, soaked 1 hour, endured then 1 hour, take out the medicine juice of enduring out; 2 add water again in medicine material endured 2 hours again, took out the medicine juice of enduring out again; 3, with above-mentioned 1,2 twice obtained medicine juice, through being condensed into pasty state; 4, above-mentioned pastel is dried, it is encapsulated to grind to form thin foam then.Every of general 0.5 gram.

Motherland's medical science thinks that the kidney being the origin of congenital constitution, the root of life, kidney storing essence is the source of people's bulk-growth growth, for vital movement this.The prosperity and decline of kidney essense gas, the growth, growth, the strong prosperity and decline that are directly connected to human body are old, influence sexual function and reproductive performance, therefore the negative and positive of necessary conditioned kidney when treatment.This preparation focuses on the QI invigorating tonifying YANG with Radix Ginseng, Cornu Cervi Pantotrichum, Herba Epimedii, Radix Morindae Officinalis, Fructus Rubi, field dobber, nourishing the liver and kidney, the equilibrium between yin and yang at adjusting kidney mansion.According to modern medicine study, the Cornu Cervi Pantotrichum chemical constituent contains hormone, and the weight of prostate, seminal vesicle is increased, and shows as the effect of androgen sample.The Herba Epimedii composition has the gonepoietic effect of promotion, and prostate, weight of seminal vesicle are increased, kidney-replenishing, and benefiting essence-blood increases motility of sperm, enhances metabolism, and improves the accessory gland effect, promotes cell development.Teratospermia is many to be caused by chronic deficiency of kidney-YIN, damp invasion of lower energizer etc., clinical see before row adenitis or seminal vesiculitis more, and deficiency of kidney yin is the major reason of sperm deformity.Fructus Lycii, Semen Allii Tuberosi, Radix Angelicae Sinensis, energy such as Herba Cistanches, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Radix Rehmanniae YIN nourishing, replenishing essence, the kidney invigorating reduce the smart factor that causes, and reduce teratospermia.

The present invention treats 1038 routine patients through following clinical trial, and wherein the age is 20～30 years old 823 example, 30～0 years old 215 example; Peasant's 505 examples, teacher's 96 examples, workman's 333 examples; Builder's 95 examples wherein, cadre's 104 examples; 2～5 years marriageable ages person's 594 examples, 5～10 years person's 362 examples, person's 82 examples more than 10 years.Semen efamination: few positive 505 examples of sperm, azoospermia 341 examples, teratospermia 26 examples, oligo-astheno-teratospermia's 42 examples, smart disease 53 examples of loss of fecundity, aspermia disease 30 examples, lack of quantity of spermatic fluid disease 19 routine seminal fluid not liquefaction disease 22 examples.Its diagnostic criteria is: oligospermatism: sperm concentration is lower than 20 * 10 ⁶/ ml.Azoospermia: have that proal sperm is less than 50% (A level+B level) or A level sperm is less than 25%.Teratozoospermia: the sperm with normal morphology is less than 30%.Oligo-astheno-teratospermia: represent the unusual of three kinds of variablees.Azoospermia: do not have sperm in the emission seminal fluid.Aspermia disease: anejaculation.Lack of quantity of spermatic fluid disease: arrange semen volume＜1ml at every turn, be not enough to dilute the acidic secretion thing of vagina and influence fertility.Therapeutic Method is: the said medicine raw material is made capsule according to proportioning, every 0.5 gram.Usage is: every day 3 times, and each two, one after each meal, three months is a course of treatment.Period in a medicine avoids pungent food, and avoids cold and uncooked food, and gives up alcohol.The treatment standard is: cure: wife's side gestation; Produce effects: more than sperm count 4,000 ten thousand/ml, the sperm survival rate is more than 80%, and motility of sperm A level+B level sperm is more than 50%; Effectively: treatment back sperm quantity increases, and survival rate improves.Other indexs are clearly better; Invalid: as to treat 2 courses of treatment, every index no change.Therapeutic outcome: see the following form 1

Table 1

The sick kind	Total routine number	Cure	Produce effects	Effectively	Invalid	Effective percentage
The sick kind	Total routine number	Cure	Produce effects	Effectively	Invalid	Effective percentage	Asthénospermie asthenoteratozoospermia oligo-astheno-teratospermia azoospermia aspermia disease lack of quantity of spermatic fluid disease disease of not liquefied sperm adds up to	????505 ????341 ????42 ????53 ????30 ????19 ????22 ????1038	????281 ????198 ????8 ????0 ????0 ????10 ????20 ????523	????224 ????143 ????31 ????0 ????0 ????8 ????2 ????424	????～ ????～ ????3 ????0 ????0 ????1 ????～ ????8	??0 ??0 ??0 ??53 ??30 ??0 ??0 ??83	????100％ ????100％ ????100％ ????0 ????0 ????100％ ????100％ ????92.1％

Table 2 spermatogenesis curative effect and time relationship

Curative effect	The example number	The spermatogenesis time
		The spermatogenesis time			1～2 month	3～4 months	4～5 months
		Curing the produce effects enabledisable adds up to	????523 ????424 ????8 ????83 ????1038	?202 ?201 ?5 ?0 ?408	1～2 month	3～4 months	4～5 months	????202 ????223 ????3 ????0 ????547	????0 ????0 ????0 ????0 ????83

Conclusion: we are not difficult to find out from table 1: this preparation is except that invalid to the patient of azoospermia (being testicular spermatogenic function obstacle or semen deposition pipeline obstruction) and aspermia disease (anejaculation or retrograde ejaculation), its curative effect of other diseases patient is all reached 100%, and total effective rate is 92.1%.From table 2 we as can be seen this preparation take 1～2 month promptly effectively, effect was the most obvious in 2～3 months.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1: get Radix Ginseng 6 Cornu Cervi Pantotrichums 10 Hippocampus 10 Radix Morindae Officinaliss 6 Fructus Schisandrae Chinensis 10 Fructus Lycii 60 Fructus Ligustri Lucidi 10 field dobbers 100 Fructus Rosae Laevigatae 10 Fructus Rubies 10 Semen Plantaginiss 10 Radix Angelicae Sinensis 10 Radix Rehmanniae 10 Herba Cistanches 10 Herba Epimedii 20 Fructus Cnidiis 10 Semen Allii Tuberosi 10 Fructus Toosendans 10 according to following weight proportion (gram).According to following step 1, above-mentioned each herbal medicine raw material is weighed up in proportion, soaked 1 hour, endured then 1 hour, take out the medicine juice of enduring out; 2 add water again in medicine material endured 2 hours again, took out the medicine juice of enduring out again; 3, with above-mentioned 1,2 twice obtained medicine juice, through being condensed into pasty state; 4, above-mentioned pastel is dried, it is encapsulated to grind to form thin foam then.Every of general 0.5 gram.

Embodiment 2: get Radix Ginseng 10 Cornu Cervi Pantotrichums 15 Hippocampus 20 Radix Morindae Officinaliss 15 Fructus Schisandrae Chinensis 20 Fructus Lycii 100 Fructus Ligustri Lucidi 15 field dobbers 150 Fructus Rosae Laevigatae 15 Fructus Rubies 20 Semen Plantaginiss 15 Radix Angelicae Sinensis 20 Radix Rehmanniae 20 Herba Cistanches 20 Herba Epimedii 50 Fructus Cnidiis 20 Semen Allii Tuberosi 20 Fructus Toosendans 20 according to following weight proportion (gram).Preparation method according to embodiment 1 is made capsule.

Embodiment 2: get Radix Ginseng 20 Cornu Cervi Pantotrichums 20 hippocampus 3s 0 Radix Morindae Officinalis 30 Fructus Schisandrae Chinensis 30 Fructus Lycii 200 Fructus Ligustri Lucidi 20 field dobbers 200 Fructus Rosae Laevigatae 20 Fructus Rubies 40 Semen Plantaginiss 30 Radix Angelicae Sinensis 30 Radix Rehmanniae 30 Herba Cistanches 30 Herba Epimedii 100 Fructus Cnidiis 30 Semen Allii Tuberosi 30 Fructus Toosendans 30.Preparation method according to embodiment 1 is made capsule.

Claims

1, a kind of Chinese patent medicine for the treatment of male infertility is characterized in that: the medicament that this medicine is made up of the following weight proportion raw material (gram): Radix Ginseng 6-20 Cornu Cervi Pantotrichum 10-20 Hippocampus 10-30 Radix Morindae Officinalis 6-30 Fructus Schisandrae Chinensis 10-30 Fructus Lycii 60-200 Fructus Ligustri Lucidi 10-20 field dobber 100-200 Fructus Rosae Laevigatae 10-20 Fructus Rubi 10-40 Semen Plantaginis 10-30 Radix Angelicae Sinensis 10-30 Radix Rehmanniae 10-30 Herba Cistanches 10-30 Herba Epimedii 20-100 Fructus Cnidii 10-30 Semen Allii Tuberosi 10-30 Fructus Toosendan 10-30.

2, a kind of Chinese patent medicine for the treatment of male infertility according to claim 1, it is characterized in that: the dosage form of described Chinese patent medicine can be: different dosage forms such as pill, sublimed preparation, powder, decoction and capsule powder.