CN112439039A - Medicine for rapidly promoting male fertility and sexual function - Google Patents

Medicine for rapidly promoting male fertility and sexual function Download PDF

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CN112439039A
CN112439039A CN201910857344.7A CN201910857344A CN112439039A CN 112439039 A CN112439039 A CN 112439039A CN 201910857344 A CN201910857344 A CN 201910857344A CN 112439039 A CN112439039 A CN 112439039A
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medicine
sexual function
male fertility
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王忠民
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
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    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/52Juglandaceae (Walnut family)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

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Abstract

The invention discloses a medicine for rapidly promoting male fertility and sexual function, which is prepared from raw materials of sharpleaf galangal fruit, rhizoma polygonati, honeysuckle flower, oyster, hawthorn fruit, pine pollen, medlar, mulberry, dogwood, ginseng, astragalus, walnut kernel, peach kernel, cistanche and raspberry by a conventional process of traditional Chinese medicine pharmacy according to a certain weight ratio. Clinical observation and laboratory prove that the traditional Chinese medicine composition has quick and obvious treatment effects on the reduction of the number of sperms, low vitality, insufficient vitality, excessive teratospermia and the like, and has good effects on promoting male sexual desire and improving sexual function. According to clinical contrast observation, the medicine has quick effect, is superior to similar medicines, and has no toxic or side effect.

Description

Medicine for rapidly promoting male fertility and sexual function
Technical Field
The invention relates to a medicine for rapidly promoting male fertility and sexual function, in particular to a medicine which is prepared by taking animal and plant traditional Chinese medicines and all traditional Chinese medicines which can be used as both medicine and food as raw materials, has the function of treating both symptoms and root causes and can promote male fertility and health.
Background
The decline of male fertility and sexual hypofunction caused by multiple factors become common clinical diseases. In recent years, infertility caused by a decline in male fertility tends to be increased due to various adverse effects such as environmental deterioration, chemical pollution, physical factors, dietary factors, and the like, and male sexual function is also decreased to various degrees. The high incidence of the disease seriously affects the family happiness and the normal life of the couple.
In the aspect of treating male infertility, although clinically common medicaments with the spermatogenic effect such as Wuzi Yanzong pills, spermatogenic capsules, compound Formica fusca capsules and the like have certain clinical effect on improving the fertility, the dual improvement effect on the spermatogenic effect and the sexual function is not satisfactory, and a person who is prepared by a medicament and food with dual purposes in the aspect of safety does not exist, and the medicaments which can improve the reproductive capacity and the male sexual function simultaneously do not exist.
In the aspects of male sterility and male sexual health care, the traditional Chinese medicine has certain advantages, but the Chinese patent medicine has single variety and non-ideal effect, so that the diversified selections of different requirements of male sterility and sexual hypofunction patients are limited. It is especially necessary to provide a special Chinese patent medicine with higher safety and more effectiveness for clinic.
Clinical research data prove that 1 couple of couples in China has infertility in every 8-10 couples on average, wherein male factors account for 40-50%, and the male infertility causes oligospermia and asthenospermia are the most common. The western medicines for treating the male infertility are few in variety, and the curative effect of some medicines is not ideal. Modern pharmacological research finds that some traditional Chinese medicines with the effects of tonifying kidney, replenishing essence, strengthening spleen, tonifying qi and the like can change the molecular structure of sperm protein and promote the change of the membrane structure of pathological sperms to enable the pathological sperms to reach the mature state of the sperms; meanwhile, the activity of sperm enzyme LDHX can be improved, DNA synthesis is promoted, sperm energy metabolism is improved, microbial infection is inhibited, and the levels of active oxygen and lipid peroxide are reduced.
At present, the traditional Chinese medicine is still one of the main means for treating male infertility, and the curative effect and the pharmacodynamic mechanism of the traditional Chinese medicine formula are further researched so as to develop effective, reasonable, safe and economic new medicines for improving the male sperm quality. In this respect, the inventor is well-known to master traditional Chinese medicine physicians, and the guide of traditional Chinese medicine inheritance studio in Tianjin city, Wang Zhong Yi Min professor, according to more than 40 years of clinical experience, on the basis of years of clinical research of the Jing-Jibao capsule invented in 2005, through repeated observation and contrast, beneficial prescription improvement is carried out, and further, the medicine-food dual-purpose traditional Chinese medicine scientific formula is applied, so that the effectiveness of the medicine is greatly improved, the safety of the medicine is practically improved, and the clinical application range is greatly expanded.
The prescription consisting of the medicine and food dual-purpose Chinese medicaments has absolutely guaranteed safety and further expanded application range. Moreover, the cost of the medicine is reduced on the basis of improving the male fertility and having reliable curative effect on health care.
Clinically, there are few drugs that can improve male fertility and sexual function. The invention is a drug which has reliable curative effect without toxic and side effect, can rapidly control disease symptoms and can control relapse effect, and the characteristic is the original intention of the drug inventor. The medicine is still blank in the market of Chinese and western medicines.
Years of clinical observation of large-scale official third-class hospitals such as the Beijing hospital in Tianjin and the like prove that the medicine is convenient to take, quick to take, reliable in function and free of toxic and side effects in clinical observation.
Disclosure of Invention
The invention aims to provide a medicine for rapidly promoting male fertility and sexual function. The medicine is repeatedly tested by professor Wang loyalty of TCM (skilled medical professor) through large sample data, and years of clinical research and observation prove that the medicine has reliable safety and obvious treatment effect.
The medicine has rapid and obvious treatment efficacy on the symptoms of reduced sperm quantity, low sperm motility, insufficient sperm motility rate, excessive teratospermia and the like; meanwhile, the traditional Chinese medicine composition has good effects of promoting male sexual desire and improving sexual function, has good improving effects on male sexual dysfunction and premature ejaculation, and has quick response and no toxic or side effect through clinical observation.
The medicine of the invention takes the holistic concept and the treatment based on syndrome differentiation of the traditional Chinese medicine as the basic formula criteria, supplements kidney qi to replenish essence, removes stasis, activates blood to remove stagnation, promotes the generation of essence to benefit breeding, and promotes the fertility and the sexual function of men from multiple directions and ways.
A medicine for rapidly promoting male fertility and sexual function comprises fructus Alpinae Oxyphyllae, rhizoma Polygonati, flos Lonicerae, Concha Ostreae, fructus crataegi, pollen Pini, fructus Lycii, Mori fructus, Corni fructus, Ginseng radix, radix astragali, semen Juglandis, semen Persicae, Cistanchis herba, and Rubi fructus. The basic characteristics are that the recipe starts with tonifying the innate kidney and strengthening the acquired spleen to treat the primary symptoms, improves the sperm quality and increases the sperm quantity to treat the secondary symptoms, tries to treat both the primary and secondary symptoms, quickly improves the fertility of the patient and promotes the sexual desire and the sexual function.
The bitter cardamon, the medlar, the mulberry, the dogwood, the cistanche, the raspberry, the walnut kernel and the like in the formula have the leading effects of tonifying the innate kidney qi, filling the kidney essence, promoting the generation of sperms, increasing the quantity of the sperms and improving the quality of the sperms; rhizoma polygonati, hawthorn, pollen pini, ginseng and astragalus root have good effects of strengthening spleen, tonifying qi and strengthening physique and promoting sexual desire and sexual function; besides, the oyster contains 18 amino acids, glycogen and B vitamins, contains zinc which is an important trace element generated by male sperms, and has certain effects of improving the immunologic function and enhancing the physical strength; the pine pollen has the effects of benefiting qi and nourishing blood, resisting fatigue, enhancing immunity, delaying aging and the like, can regulate physiological functions, promote metabolism of skin cells and delay aging of the skin cells. Animal experiments prove that the pine pollen can obviously increase the testosterone content of male aging rats, obviously improve the number of sperms, the activity degree and the survival rate, and simultaneously has the effect of resisting gonad aging.
The honeysuckle has the functions of enhancing the immunologic function, regulating prostaglandin, eliminating inflammatory diseases and the like, and has reliable curative effect; the peach kernel has the outstanding effects of improving the hemodynamics, promoting the blood circulation of the reproductive system, improving the immunologic function, resisting inflammation and oxidation and the like.
The whole formula is overall, the medicine is clear in administration, the formula is ingenious and reasonable, and the effects complement each other. The traditional Chinese medicine and the western medicine are combined, and the syndrome differentiation and the disease differentiation are combined, and the pharmacological experiments related to modern medicine prove that the medicine used in the formula promotes the effectiveness and the reliability of sperm quality, each medicine is in the category of medicine-food dual-purpose traditional Chinese medicine, the safety is well ensured, and the pharmacological experiments and clinical observation of animals also suggest that no obvious toxic or side effect exists.
The medicine is realized by the following technical scheme. The medicine for rapidly promoting male fertility and sexual function is characterized by being prepared from the following raw material medicines in parts by weight: 5-60 parts of fructus alpiniae oxyphyllae, 5-60 parts of rhizoma polygonati, 5-60 parts of flos lonicerae, 5-60 parts of oyster, 3-60 parts of hawthorn, 5-60 parts of pollen pini, 3-55 parts of wolfberry, 5-55 parts of mulberry, 5-60 parts of dogwood, 5-60 parts of ginseng, 5-55 parts of astragalus membranaceus, 5-55 parts of walnut kernels, 5-60 parts of peach kernels, 5-55 parts of cistanche and 5-55 parts of raspberry.
The medicine of the invention embodies the characteristics of combining syndrome differentiation and disease differentiation, completely accords with the basic principle of traditional Chinese medicine treatment based on syndrome differentiation, and has scientific and precise formula.
Moreover, the pharmacological effects of the medicament are proved by related pharmacological research and animal test conclusions.
A medicine for rapidly promoting male fertility and sexual function can be made into any oral dosage form by conventional method of Chinese medicinal preparation.
The medicine for rapidly promoting male fertility and sexual function is prepared into capsules by adopting a conventional process of Chinese materia medica pharmaceutics.
The medicine for rapidly promoting male fertility and sexual function is prepared into tablets or blocks by adopting a conventional process of Chinese medicinal preparation.
The medicine for rapidly promoting male fertility and sexual function is prepared into powder or granules by adopting a conventional process of Chinese medicinal preparation.
The medicine for rapidly promoting male fertility and sexual function is prepared into water pills, honey pills, water-honey pills, concentrated pills or dropping pills by adopting a conventional process of Chinese medicinal preparation science.
The medicine for rapidly promoting male fertility and sexual function is prepared into oral liquid by adopting a conventional process of Chinese materia medica pharmaceutics.
The medicine for rapidly promoting male fertility and sexual function is prepared into tea by adopting a conventional process of Chinese materia medica pharmaceutics.
The formula of the medicine for rapidly promoting male fertility and sexual function can also adopt methods such as a semi-bionic extraction method, supercritical fluid extraction, microwave extraction, enzyme engineering technology, ultrasonic extraction, a macroporous adsorption resin method and the like to extract effective components, and the extraction methods are all within the protection scope of the invention.
Clinical research results show that the medicine for rapidly promoting male fertility and sexual function has the following advantages:
1. a medicine for rapidly promoting male fertility and sexual function is prepared from natural edible plant medicines as raw materials, and the components conform to the pharmaceutical regulation and the prescription principle of traditional Chinese medicine, and highlight the basic characteristics of the combination of traditional Chinese medicine syndrome differentiation and western medicine disease differentiation, and the combination of etiology treatment and symptomatic treatment;
2. the finished medicine oral preparation for rapidly promoting the male fertility and the sexual function has good taste and convenient taking, all the medicines are nontoxic and harmless before and after the prescription, and no toxic or side effect is found after the normal dosage is taken;
3. a medicine for rapidly promoting male fertility and sexual function has obvious promoting function on male fertility, and can rapidly improve sperm quality and normal fertility;
4. a medicine for quickly promoting male fertility and sexual function has obvious effect on male sexual function rehabilitation, and has rehabilitation effect on male sexual dysfunction such as sexual impotence and premature ejaculation;
5. a medicine for rapidly promoting male fertility and sexual function has obvious effect in relieving fatigue, improving immunity, preventing diseases, and promoting health, and has wide application range;
6. the medicine for rapidly promoting the male fertility and the sexual function is selected from the varieties which can be used as both medicine and food and are specified by the Ministry of health, the safety is higher, and the medicine can be taken for a long time during treatment;
7. the medicine for rapidly promoting male fertility and sexual function addresses both the symptoms and root causes, and has quick response and high cure rate.
Detailed Description
Clinical effect observation and safety tests show that the medicine is safe and reliable to take orally, has obvious treatment effect and has certain clinical popularization and practical value.
Example 1
5-30 parts of fructus alpiniae oxyphyllae, 5-50 parts of rhizoma polygonati, 5-30 parts of flos lonicerae, 5-60 parts of oyster, 3-40 parts of hawthorn, 5-50 parts of pollen pini, 3-55 parts of wolfberry, 5-55 parts of mulberry, 5-40 parts of dogwood, 5-30 parts of ginseng, 5-55 parts of astragalus membranaceus, 5-35 parts of walnut kernels, 5-30 parts of peach kernels, 5-45 parts of cistanche and 5-45 parts of raspberry.
According to the conventional extraction method of the traditional Chinese medicine, capsules containing 0.45 g of extracted medicinal powder are prepared.
Clinical experimental example 1: asthenospermia (asthenospermia)
General data
In order to verify the clinical effect of the medicine for rapidly promoting the male fertility and the sexual function, 182 patients with male low sperm motility are continuously observed in a centralized way in hospitals such as the third-class A and the like, and all the patients come from an outpatient clinic. 33 cases with low simple sperm density, 76 cases with low simple sperm motility, and 92 cases with low sperm density and low sperm motility; the sperm motility of grade a is less than 25%, the sperm motility of grade a is 133, and the sperm of grade a + b is less than 50%, the sperm of grade a + b is 49. The medical record number drawing method is divided into two groups at random, and the two groups are 91 cases respectively. The disease course of the treatment group is 6 months to 3 years and 5 months, and the average is 1 year and 5 months; the control group is 6 months to 3 years and 6 months, and the average is 4 half months in 1 year; the two comparisons were not statistically different. The age of the treatment group is 25-41 years, and the average age (30 +/-7.1) years; the control group is 24-41 years old, and the average age is (31 +/-6.9) years old. The difference between the disease course and the age of the two groups has no statistical significance (P is more than 0.05), and the two groups have comparability.
Diagnostic criteria
(1) Western diagnostic criteria: refer to the manual of human semen and sperm-cervical mucus interaction laboratory test. Married or not married living for more than 1 year, normal sexual life, no contraception but sterility, and normal gynecological examination of female. Routine examination of semen: sperm density < 20 × 109And/or the sperm motility of grade a is less than 25 percent, and the grade a + b is less than 50 percent.
(2) The traditional Chinese medicine diagnosis standard is as follows: is determined according to clinical practice in the guideline of clinical research of new Chinese medicines. The main symptoms of kidney deficiency syndrome: soreness and weakness of the loins and knees, apathy, nocturia and a small amount of ejaculation. The secondary symptoms are as follows: tinnitus, hair loss, amnesia, fatigue, pale tongue, deep and thready pulse.
Inclusion criteria
All the patients are male infertility patients according with relevant diagnostic standards; according to the semen collection standard of masturbation, the sperm motility is lower than normal after 2 or more than 2 times of routine examination of semen, and the sperm density is lower than 20 multiplied by 109Less than/L, or aLess than 50% of grade b, or less than 25% of grade a sperm; the couple relationship of the testee is stable, and the emotion is good; the subject voluntarily receives the clinical treatment observation; both groups are those with low sperm motility and insufficient sperm density; the sperm motility statistics of the two groups showed no significant difference.
Exclusion criteria
Two groups of patients excluded sperm antibody (AsAb) positivity; varicocele, prostatitis, seminal vesiculitis, nonliquefaction of semen, abnormal development of testis, testis atrophy, obstruction of vas deferens, testis trauma, parotitis orchitis of childhood, and functional anejaculation; clear diseases such as endocrine lesions of hypothalamus, pituitary and testis, chromosome abnormality and the like; the patients with serious primary diseases such as cardiovascular diseases, liver diseases, kidney diseases, hemopoietic systems and the like and psychonoses are definitely found; taking antiepileptic and antitumor drugs which can inhibit sperm production and sperm motility; those < 24 years of age or > 41 years of age; if the drug is not administered according to the prescription, the observed data is not complete, or the drug administration is stopped during the treatment, the curative effect cannot be determined normally.
Method of treatment
The capsule of the invention is taken by an observation group 3 times a day, 4 capsules each time (each capsule contains 0.45 g of extracted medicinal powder, produced by Yihai pharmaceutical Limited company of Jiangsu, the same below), and is taken continuously for 3 months as 1 course of treatment; 3 capsules (0.42 g each capsule, national Standard Z20060462, available from Shiqiang pharmaceutical Co., Ltd.) were orally administered to the control group 3 times per day; vitamin E capsules (national Standard H36020414, Jiangxi Tianhai pharmaceutical Co., Ltd., batch No.: 20051201, 1 capsule 100mg) 1 capsule at a time, 2 times a day. It is administered continuously for 3 months as 1 course of treatment.
In both treatment periods, the patients should refrain from smoking wine and food for a large amount of bean products and spicy food.
Observation index
(1) Observing the change of conventional examination items of semen before and after administration, wherein the observation items are the improvement conditions of two groups of a-level sperms before and after treatment: (2) observing the density increase of two groups of sperms before and after treatment: (3) the comparison of the significant efficiency and the efficiency of the two groups before and after the treatment is observed: (4) the safety of the drug of the invention was observed. The observation indexes mainly comprise ten items of Total Protein (TP), Albumin (ALB), glutamic-oxalacetic transaminase (AST), glutamic-pyruvic transaminase (ALT), urea nitrogen (BUN), inosine (CRE), blood sugar (GLU), Total Cholesterol (TC), Triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), Hemoglobin (HB), Red Blood Cells (RBC), White Blood Cells (WBC) and urine.
Criteria for therapeutic effect
The therapeutic effect judgment standard is used for evaluating the effective standard according to the WHO 'sterile couple standard inspection and diagnosis manual' and according to the relevant therapeutic effect standard in the 'clinical research and guidance principles of new traditional Chinese medicine'. (1) And observing effective standard of sperm motility. The effect is shown: the grade a + b is more than 50% or the grade a is more than 25% after the sperm motility treatment, and the survival rate is more than 60%; the method has the following advantages: the activity of the sperms is improved by more than 30 percent in grade a + b or grade a, and the survival rate is improved by more than 30 percent; and (4) invalidation: the sperm motility is improved by less than 30% or has no change after treatment. (2) Effective standard is observed on sperm density. The effect is shown: the density of sperms is increased to the normal range after being treated by patients with lower sperm density than the normal range; the method has the following advantages: the density of the treated sperms is improved by more than or equal to 30 percent on the basis of the original inspection result; and (4) invalidation: the density of the treated sperms is improved by less than 30 percent or is unchanged on the original basis. (3) And (5) comprehensive therapeutic effect analysis standards. The effect is shown: sperm density > 20X 109The indexes of more than 50% of/L, a + b-grade sperms and more than 25% of a-grade sperms reach the standard; the method has the following advantages: the two indexes of the sperm density, the a + b level sperm and the a level sperm reach the standard or the three indexes are improved; and (4) invalidation: only one of the indexes of the sperm density, the grade a + b sperm and the grade a sperm reaches the standard or less than one reaches the standard.
Statistical treatment
Using SPSS13.0 statistical software to calculate data
Figure BSA0000190077160000051
Showing that the random data t test is used for the comparison between groups and the chi test is used for the counting data2The test shows that the difference is statistically significant when P is less than 0.05.
Therapeutic results
The curative effect standard is as follows: the evaluation is carried out according to the relevant curative effect standards in WHO ' sterile couple standard inspection and diagnosis manual ' and according to the guiding principles of clinical research of new traditional Chinese medicines '. The effect is shown: after the sperm motility treatment, the grade a plus grade b is more than 50 percent or the grade a is more than 25 percent, and the survival rate is more than 60 percent after 1 hour; the method has the following advantages: the sperm motility a plus b grade or a grade is improved by more than 30 percent, and the survival rate is improved by more than 30 percent after 1 hour; and (4) invalidation: the sperm motility is improved by less than 30% or has no change after treatment.
Comparison of grade a sperm enhancement in two groups
Before treatment, the activity of two groups of simple grade a sperms is lower than that of normal people in 76 cases, and the activity is obviously improved after treatment. The inventor statistically processes the front and back change conditions of 37 cases of the drug observation group and 39 cases of the control group with low simple density, and the two groups have significant difference. The observation group is 10.22 +/-3.55 before treatment and 25.86 +/-4.79 after treatment; the control group is 10.21 + -3.48 before treatment and 19.21 + -5.77 after treatment. The statistically treated observed group was significantly better than the control group.
Comparison of increase in sperm density between the two groups
The simple density of sperms in two groups is lower than that in normal cases, and the sperms in the two groups are all obviously improved after treatment. The inventor compares the 16 cases with the 17 cases with the low simple density in the observation group statistically, and the result shows that the two groups have significant difference. Observation group 22 (. times.10)9/L)16.57 + -6.35, 31.23 + -9.51 after treatment; control group 21 (. times.10)9/L) 16.13 + -6.62 before treatment and 19.07 + -7.45 after treatment. The statistically treated observed group was significantly better than the control group.
The two groups of display efficiency are compared with the total effective rate
After 1 treatment course, the result shows that the significant efficiency and the total effective rate of the drug observation group are higher than those of the control group, and the two groups have significant difference, wherein P is less than 0.05. The significant efficiency of the observation group is 65.9 percent, the significant efficiency of the control group is 40.7 percent, and the two groups are statistically treated to have significant difference (P is less than 0.01); the total effective rate of the observation group is 94.5%, the total effective rate of the control group is 80.2%, and the two groups have statistical difference (P is less than 0.05).
Safety of the drug of the invention
The ten indexes of TP, ALB, AST, ALT, BUN, CRE, GLU, TC, TG, HDL-C, HB, RBC, WBC and urine after the observation group treatment have no statistical difference compared with the indexes before the treatment.
Clinical example 2: male sexual dysfunction
General data
Case selection: 116 cases of male sexual dysfunction were observed. Randomly dividing the medical record into two groups according to a medical record number drawing method, wherein the observed group and the control group are 58 cases; the average age of the two groups is 33 +/-8.2 years, the disease course is 6 months to 2 years and 9 months, and the average age is 1 year and 6 months; there were 56 cases of medication and 19 cases of psychological treatment.
The cases were all from the clinic, randomized into two groups, and no significant difference between groups.
Observation standard: refer to the guidelines for clinical research of new Chinese drugs for the diagnosis of male sexual dysfunction. And depending on the clinical manifestations of the individual patients, one of the following 3 events can be included: 1. under the requirements of sexual desire and sex, the penis can not erect and normal sexual intercourse can not be carried out; 2. when sexual desire exists, the penis can erect, but the erection strength or hardness is not enough, and the penis is difficult to put into the vagina to complete normal intercourse; 3. when sexual desire exists, the penis can erect and the erection degree or hardness is still enough, but the erection is maintained for a short time, and the penis is not placed in the vagina or is flaccid after being placed in the vagina, so that normal sexual intercourse cannot be realized.
Method of treatment
Observation group: the medicine capsule is taken 3 times a day, 4 capsules (each capsule contains 0.45 g of extracted medicine powder) are taken each time, and 3 months are 1 course of treatment.
Control group: taking Wuzi Yanzong pill (Luoyang Junshan pharmacy Co., Ltd., Chinese medicine standard character Z21020225) 6g each time, 2 times each day, and vitamin E (Beijing Shuanghe pharmaceutical industry Co., Ltd., Chinese medicine standard character H11021397) 100mg each time, 2 times each day. It is administered continuously for 3 months as 1 course of treatment.
Therapeutic results
The therapeutic effect judgment standard is as follows: the therapeutic effect standard refers to the therapeutic effect grade and related industry standard of the clinical research guiding principle of new traditional Chinese medicine, and the therapeutic effect evaluation standard of the male sexual dysfunction is drawn up. Clinical cure: the penis can naturally enter the vagina after erection to complete normal sexual intercourse, the sexual life is satisfactory, and the sexual intercourse success rate is more than or equal to 75 percent; the effect is shown: the penis erection is held by hands to enter the vagina for sexual intercourse, the sexual life is basically satisfied, and the sexual intercourse success rate is 50-74 percent; the method has the following advantages: the penis erection function is improved but can not smoothly enter the vagina before treatment, occasionally, the penis erection function can be held by hands to enter the vagina for sexual intercourse, the sexual life is unsatisfactory, and the success rate of the sexual intercourse is 26-49 percent; and (4) invalidation: compared with the treatment before, the sexual intercourse is not changed or aggravated, the sexual intercourse is not satisfied, and the success rate of the sexual intercourse is less than 25 percent.
The statistical method comprises the following steps: using SPSS13.0 statistical software to calculate data
Figure BSA0000190077160000071
Showing that the random data t test is used for the comparison between groups and the chi test is used for the counting data2The test shows that the difference is statistically significant when P is less than 0.05.
And (3) analyzing the curative effect: after 1 treatment course, the clinical cure rate and the total effective rate of an observation group are obviously higher than those of a control group. Wherein 30 cases of clinical cure of the observation group are achieved, and the clinical cure rate is 51.7%; 15 cases of the control group are cured clinically, and the clinical cure rate is 25.9 percent; the two groups of comparison have significant difference, and P is less than 0.01. Wherein, 53 observation groups are effective, and the total effective rate is 91.4%; the control group has 45 effective cases, and the total effective rate is 77.6 percent; two comparisons showed statistical differences, P < 0.05.

Claims (7)

1. The medicine for rapidly promoting male fertility and sexual function is characterized by being prepared from the following raw material medicines in parts by weight:
Figure FSA0000190077150000011
2. the medicine for rapidly promoting male fertility and sexual function according to claim 1, wherein the capsule is prepared by a conventional process of Chinese materia medica pharmaceutics.
3. The medicine for rapidly promoting male fertility and sexual function according to claim 1, wherein the medicine is prepared into tablet or block by conventional technique of Chinese materia medica preparation.
4. The medicine for rapidly promoting male fertility and sexual function according to claim 1, wherein the medicine is prepared into powder or granules by a conventional process of Chinese materia medica preparation.
5. The medicine for rapidly promoting male fertility and sexual function as claimed in claim 1, wherein the pill, honeyed pill, watered honeyed pill, concentrated pill or drop pill is prepared from the herbs by conventional process.
6. The medicine for rapidly promoting male fertility and sexual function according to claim 1, wherein the oral liquid is prepared by a conventional process of Chinese materia medica pharmaceutics.
7. The medicine for rapidly promoting male fertility and sexual function according to claim 1, wherein the medicine is prepared into tea by a conventional process of Chinese materia medica pharmaceutics.
CN201910857344.7A 2019-09-04 2019-09-04 Medicine for rapidly promoting male fertility and sexual function Pending CN112439039A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1104908A (en) * 1994-08-05 1995-07-12 黄有康 Nutrient health medicinal liquor
CN1194860A (en) * 1998-04-20 1998-10-07 白景亮 Agentia for improving genitality and producing process thereof
CN1686207A (en) * 2005-04-29 2005-10-26 胡春福 Ready prepared Chinese medicine for treating male sterility
CN109420104A (en) * 2017-09-05 2019-03-05 许国华 Ginseng King solomonseal rhizome tea

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1104908A (en) * 1994-08-05 1995-07-12 黄有康 Nutrient health medicinal liquor
CN1194860A (en) * 1998-04-20 1998-10-07 白景亮 Agentia for improving genitality and producing process thereof
CN1686207A (en) * 2005-04-29 2005-10-26 胡春福 Ready prepared Chinese medicine for treating male sterility
CN109420104A (en) * 2017-09-05 2019-03-05 许国华 Ginseng King solomonseal rhizome tea

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