CN1682610A - Chinese yew fruit nectar formulation and its preparing process - Google Patents
Chinese yew fruit nectar formulation and its preparing process Download PDFInfo
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- CN1682610A CN1682610A CN 200410017818 CN200410017818A CN1682610A CN 1682610 A CN1682610 A CN 1682610A CN 200410017818 CN200410017818 CN 200410017818 CN 200410017818 A CN200410017818 A CN 200410017818A CN 1682610 A CN1682610 A CN 1682610A
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Abstract
The Chinese yew fruit tea is prepared with Chinese yew fruit 30-40 wt%, Chinese yew tree powder 13-17 wt%, wild buckwheat root 17-23 wt% and golden tea 25-35 wt%. The preparation process includes stoving and crushing Chinese yew fruit, Chinese yew tree powder and wild buckwheat root, mixing, re-crushing the mixture at 90 deg.c, ultraviolet ray disinfecting the mixing under vacuum environment at 50 deg.c, mixing with fried golden tea, and packing the mixture with non-woven fabric bag in 3 g each. The present invention has excellent effect of preventing and treating kidney disease, diabetes, rheumatism and cancer.
Description
Technical field
The present invention relates to a kind of fruit juice, especially relate to prescription and the preparation technology thereof of a kind of Ramulus et folium taxi cuspidatae fruit juice.
Background technology
Ramulus et folium taxi cuspidatae claims Ramulus et folium taxi cuspidatae again, is the ancient seeds that quaternary glacier carries over, on earth the history in existing 2,500,000 years.Ramulus et folium taxi cuspidatae has very high medical value, be precious from head to foot, wherein, leaves contains the taxine diterpene compound, and taxinine, taxinine A, taxinine H, taxinine K, taxinine L, parasol pine flavone, sloping that stay ketone A, cast off a skin and stay ketone, 7,4',4'''-Trimethylamentoflavone, volatile oil, sugar etc.; Peel of stem contains taxol and has leukemia and function of tumor; Branch contains taxine, and taxusin is contained in the pith.Taxine has hypoglycemic effect to hypertension (epinephrine or food); Branch and leaf be used as medicine all have stimulate the menstrual flow, the effectiveness of diuresis, inhibition diabetes and treatment heart disease.The just record of the classical Compendium of Material Medica of motherland's medical science, can treat cholera, typhoid fever, toxin expelling, in the medical books such as modern " Chinese medicine voluminous dictionary ", " the northeast medicine is planted will ", " Jilin Chinese herbal medicine ", " book on Chinese herbal medicine pushes away old " further record is arranged, also record can be gone into kidney channel: 1, inducing diuresis to remove edema, the treatment nephropathy, diabetes, nephritis edema; dysuria, diseases such as gonorrhea; 2, the kidney warming stimulates the menstrual flow: treatment menoxenia, postnatal blood stasis, dysmenorrhea etc.Utilize the project of Ramulus et folium taxi cuspidatae exploitation a lot of now; it such as publication number 1440967 patent " method of paclitaxel synthesis "; it discloses (the 2R of the first C3 of using ' N-CBZ-C2 '-O-protection; 3S)-3-phenylisoserine side chain is the esterification of C7-CBZ Baccatine III; form first midbody compound; replace the benzyloxycarbonyl group of this first intermediate C-7 position and C3 ' nitrogen position then respectively with hydrogen and PhCO, obtain second intermediate, the protecting group that replaces C2 ' position with hydrogen is carried out deprotection then.C2 ' position protecting group is the benzylic type protecting group, preferably benzyloxymethyl or benzyl.Use the above-mentioned side chain of excessive (for example 6 equivalents).In esterification process, preferably also use DMAP and dialkyl group carbodiimide.Various preferred reaction temperatures, time and purification step are disclosed in addition.Also has the patented technology that much openly prepares the taxus chinensis wine beverage.Obviously, preparation paclitaxel and Wine all need comparatively complicated technology, although paclitaxel is the optimal drug of treatment cancer, but its cost of manufacture is very high, the paclitaxel international market price of present 98% purity is 40 to 600,000 dollars every kilogram, China's purity is that 70% paclitaxel price is 160 to 1,800,000 yuan/kilogram, and is also more expensive than the price of gold, causes it to be difficult to apply; And Wine has very strong zest, also is difficult to popularize.Also have; Ramulus et folium taxi cuspidatae is the first-grade state protection plant; above-mentioned exploration project all needs a lot of Ramulus et folium taxi cuspidatae branch, trunk, tree to follow etc. to do raw material; this has run counter to national protective policy; and Ramulus et folium taxi cuspidatae is all born a lot of fruits every year; but do not make full use of, do not find that also a kind of is the product of primary raw material with the taxus fruit at present.
Summary of the invention
The present invention solves existing in prior technology Ramulus et folium taxi cuspidatae product preparation process complexity, production cost costliness, the technical problem that is unfavorable for applying etc.
The present invention has also solved the technical problem that the existing in prior technology taxus fruit fails to make full use of etc., and providing a kind of is prescription and the preparation technology thereof of the Ramulus et folium taxi cuspidatae fruit juice of primary raw material with the taxus fruit.
Above-mentioned technical problem of the present invention is mainly solved by following technical proposals: the component of japanese yew fruit tea prescription (weight ratio) is: japanese yew fruit 25-45%; Ramulus et folium taxi cuspidatae wood powder material 10-20%; Fgopyrum dibotrys Hara 15-25%; Chimonanthus salicifolius S.Y.Hu. 20-40%.Its preparation technology's step is: a. is dried taxus fruit, Ramulus et folium taxi cuspidatae wood powder material and Fgopyrum dibotrys Hara respectively; B. after the oven dry, Fgopyrum dibotrys Hara is pulverized; C. the pulverized particles of Ramulus et folium taxi cuspidatae wood powder material and Fgopyrum dibotrys Hara is mixed with taxus fruit, and then pulverize together; D. under vacuum environment, again the hybrid particles after the above-mentioned pulverizing is sterilized; E. get the good Chimonanthus salicifolius S.Y.Hu. of parch, the pulverized particles of pressing configuration proportion and pulverized particles, Ramulus et folium taxi cuspidatae wood powder material and the Fgopyrum dibotrys Hara of taxus fruit is uniform mixing mutually; F. by every bag of 2.5-3.5 gram packed finished product of non-woven cotton cloth bag.
Wherein, Fgopyrum dibotrys Hara [Fagopyyum Cymosum (Trev.) Meisn] " the southern regions of the Yunnan Province book on Chinese herbal medicine " attend to the basic or the fundamental the volume 2 the 32nd pages on the books.
As preferably, the component of described prescription (weight ratio) is: japanese yew fruit 30-40%; Ramulus et folium taxi cuspidatae wood powder material 13-17%; Fgopyrum dibotrys Hara 17-23%; Chimonanthus salicifolius S.Y.Hu. 25-35%.
As preferably, the granularity of described Ramulus et folium taxi cuspidatae wood powder material granule and Fgopyrum dibotrys Hara pulverized particles is suitable, and its particle size range is that average diameter is between 0.5-1.5mm.
As preferably, the mixture of described pulverizing Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles and taxus fruit carries out under 80-100 ℃ of situation; The pulverized particles of described taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles.Like this, because taxus fruit contains sugar part, suitably heating in the process of pulverizing, the taxus fruit particle surface becomes sticky, and makes Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles stick to its surface uniformly.
Therefore, it is easy that the present invention has a selection, preparation technology is simple, low production cost, use also easily, product is the bagged granules thing, and being taken after being infused in hot water or decoction with boiled water gets final product, characteristics such as flavor perfume is tasty and refreshing, mellow, through check, product of the present invention contains paclitaxel 2.2%, aminoacid 2.2%, total sugar 22.5%, vitamin 0.3%, caffeine 0.03%, tea polyphenols 1.5%, have be good for the stomach, removing food stagnancy food, ascarifuge, blood pressure lowering, with effects such as blood glucose, the kidney invigorating, to treatment kidney disease, diabetes, rheumatism with anticancer favorable effects arranged all.
The specific embodiment
Below by embodiment, technical scheme of the present invention is described in further detail.
Embodiment 1: take 17 parts of Fgopyrum dibotrys Hara, dry and be ground into the granule of average diameter between 0.5-1.5mm; Take 15 parts in the Ramulus et folium taxi cuspidatae wood powder material suitable, oven dry with Fgopyrum dibotrys Hara pulverized particles granularity; Take 40 parts of japanese yew fruits, mix with the Fgopyrum dibotrys Hara pulverized particles and the Ramulus et folium taxi cuspidatae wood powder material of having dried oven dry back, under 90 ± 5 ℃ of situations, pulverize once more in the lump, and the pulverized particles of taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles, because taxus fruit contains sugar part, suitably heating in the process of pulverizing, the taxus fruit particle surface becomes sticky, and makes Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles stick to its surface uniformly; Under vacuum environment, adopt 50 ℃ of sterilizations of ultraviolet and dry above-mentioned pulverized particles; Take 28 parts of the good Chimonanthus salicifolius S.Y.Hu. of parch, the pulverized particles of pressing configuration proportion and pulverized particles, Ramulus et folium taxi cuspidatae wood powder material and the Fgopyrum dibotrys Hara of taxus fruit is uniform mixing mutually; By the every bag 3 gram packed finished product of non-woven cotton cloth bag.
The present invention brews with boiled water, adds a cover 8 minutes, can brew 3-4 time continuously, all-ages, flavor is fragrant tasty and refreshing, mellow, have be good for the stomach, removing food stagnancy food, ascarifuge, blood pressure lowering, with effects such as blood glucose, the kidney invigorating, to prevention and treatment kidney disease, diabetes, rheumatism with anticancer favorable effects arranged all.
Embodiment 2: take 23 parts of Fgopyrum dibotrys Hara, dry and be ground into the granule of average diameter between 0.5-1.5mm; Take 17 parts in the Ramulus et folium taxi cuspidatae wood powder material suitable, oven dry with Fgopyrum dibotrys Hara pulverized particles granularity; Take 30 parts of japanese yew fruits, mix with the Fgopyrum dibotrys Hara pulverized particles and the Ramulus et folium taxi cuspidatae wood powder material of having dried oven dry back, under 90 ± 5 ℃ of situations, pulverize once more in the lump, and the pulverized particles of taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles, because taxus fruit contains sugar part, suitably heating in the process of pulverizing, the taxus fruit particle surface becomes sticky, and makes Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles stick to its surface uniformly; Under vacuum environment, adopt 50 ℃ of sterilizations of ultraviolet and dry above-mentioned pulverized particles; Take 30 parts of the good Chimonanthus salicifolius S.Y.Hu. of parch, the pulverized particles of pressing configuration proportion and pulverized particles, Ramulus et folium taxi cuspidatae wood powder material and the Fgopyrum dibotrys Hara of taxus fruit is uniform mixing mutually; By the every bag 3 gram packed finished product of non-woven cotton cloth bag.
All the other reference examples 1.
Embodiment 3: take 20 parts of Fgopyrum dibotrys Hara, dry and be ground into the granule of average diameter between 0.5-1.5mm; Take 15 parts in the Ramulus et folium taxi cuspidatae wood powder material suitable, oven dry with Fgopyrum dibotrys Hara pulverized particles granularity; Take 35 parts of japanese yew fruits, mix with the Fgopyrum dibotrys Hara pulverized particles and the Ramulus et folium taxi cuspidatae wood powder material of having dried oven dry back, under 90 ± 5 ℃ of situations, pulverize once more in the lump, and the pulverized particles of taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles, because taxus fruit contains sugar part, suitably heating in the process of pulverizing, the taxus fruit particle surface becomes sticky, and makes Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles stick to its surface uniformly; Under vacuum environment, adopt 50 ℃ of sterilizations of ultraviolet and dry above-mentioned pulverized particles; Take 30 parts of the good Chimonanthus salicifolius S.Y.Hu. of parch, the pulverized particles of pressing configuration proportion and pulverized particles, Ramulus et folium taxi cuspidatae wood powder material and the Fgopyrum dibotrys Hara of taxus fruit is uniform mixing mutually; By the every bag 3 gram packed finished product of non-woven cotton cloth bag.
All the other reference examples 1.
Claims (7)
1. the prescription of a Ramulus et folium taxi cuspidatae fruit juice is characterized in that the component (weight ratio) of described prescription is:
Japanese yew fruit 25-45%
Ramulus et folium taxi cuspidatae wood powder material 10-20%
Fgopyrum dibotrys Hara 15-25%
Chimonanthus salicifolius S.Y.Hu. 20-40%
2. the prescription of Ramulus et folium taxi cuspidatae fruit juice according to claim 1 is characterized in that the component (weight ratio) of described prescription is:
Japanese yew fruit 30-40%
Ramulus et folium taxi cuspidatae wood powder material 13-17%
Fgopyrum dibotrys Hara 17-23%
Chimonanthus salicifolius S.Y.Hu. 25-35%
3. the preparation technology of a Ramulus et folium taxi cuspidatae fruit juice, it is characterized in that described preparation technology's step is: a. is dried taxus fruit, Ramulus et folium taxi cuspidatae wood powder material and Fgopyrum dibotrys Hara respectively; B. after the oven dry, Fgopyrum dibotrys Hara is pulverized; C. the pulverized particles of Ramulus et folium taxi cuspidatae wood powder material and Fgopyrum dibotrys Hara is mixed with taxus fruit, and then pulverize together; D. under vacuum environment, again the hybrid particles after the above-mentioned pulverizing is sterilized; E. get the good Chimonanthus salicifolius S.Y.Hu. of parch, the pulverized particles of pressing configuration proportion and pulverized particles, Ramulus et folium taxi cuspidatae wood powder material and the Fgopyrum dibotrys Hara of taxus fruit is uniform mixing mutually; F. by every bag of 2.5-3.5 gram packed finished product of non-woven cotton cloth bag.
4. the preparation technology of Ramulus et folium taxi cuspidatae fruit juice according to claim 3 is characterized in that the granularity of described Ramulus et folium taxi cuspidatae wood powder material granule and Fgopyrum dibotrys Hara pulverized particles is suitable, and its particle size range is that average diameter is between 0.5-1.5mm.
5. the preparation technology of Ramulus et folium taxi cuspidatae fruit juice according to claim 3 is characterized in that the mixture of described pulverizing Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles and taxus fruit carries out under 80-100 ℃ of situation.
6. the preparation technology of Ramulus et folium taxi cuspidatae fruit juice according to claim 3 is characterized in that the pulverized particles of described taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles.
7. the preparation technology of Ramulus et folium taxi cuspidatae fruit juice according to claim 5 is characterized in that the pulverized particles of described taxus fruit is all more bigger than Ramulus et folium taxi cuspidatae wood powder material granule, Fgopyrum dibotrys Hara pulverized particles.
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CN 200410017818 CN1682610A (en) | 2004-04-13 | 2004-04-13 | Chinese yew fruit nectar formulation and its preparing process |
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CN 200410017818 CN1682610A (en) | 2004-04-13 | 2004-04-13 | Chinese yew fruit nectar formulation and its preparing process |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101401828B (en) * | 2008-09-24 | 2011-01-12 | 上海康桥中药饮片有限公司 | Technique for processing yew decoction tablet |
CN101983575A (en) * | 2010-11-26 | 2011-03-09 | 江西荣通农业发展有限公司 | Yew leaf tea and compound tea containing same as well as preparation methods thereof |
CN102696829A (en) * | 2012-06-13 | 2012-10-03 | 何明福 | Tea drink, scented tea and preparation method of same |
CN104161111A (en) * | 2014-08-26 | 2014-11-26 | 湖南绿博农业综合开发有限公司 | Processing method of dried Chinese yew fruits |
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2004
- 2004-04-13 CN CN 200410017818 patent/CN1682610A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101401828B (en) * | 2008-09-24 | 2011-01-12 | 上海康桥中药饮片有限公司 | Technique for processing yew decoction tablet |
CN101983575A (en) * | 2010-11-26 | 2011-03-09 | 江西荣通农业发展有限公司 | Yew leaf tea and compound tea containing same as well as preparation methods thereof |
CN102696829A (en) * | 2012-06-13 | 2012-10-03 | 何明福 | Tea drink, scented tea and preparation method of same |
CN104161111A (en) * | 2014-08-26 | 2014-11-26 | 湖南绿博农业综合开发有限公司 | Processing method of dried Chinese yew fruits |
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