CN1666760A - Medicine for treating chicken respiratory diseases - Google Patents
Medicine for treating chicken respiratory diseases Download PDFInfo
- Publication number
- CN1666760A CN1666760A CN 200410010116 CN200410010116A CN1666760A CN 1666760 A CN1666760 A CN 1666760A CN 200410010116 CN200410010116 CN 200410010116 CN 200410010116 A CN200410010116 A CN 200410010116A CN 1666760 A CN1666760 A CN 1666760A
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- Prior art keywords
- medicine
- herba
- chicken
- radix
- isatidis
- Prior art date
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- 239000003814 drug Substances 0.000 title claims abstract description 37
- 241000287828 Gallus gallus Species 0.000 title claims abstract description 34
- 208000023504 respiratory system disease Diseases 0.000 title claims abstract description 19
- 229940079593 drug Drugs 0.000 title description 9
- 239000000843 powder Substances 0.000 claims abstract description 15
- 241000746375 Andrographis Species 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 241000218671 Ephedra Species 0.000 claims abstract description 6
- 239000010231 banlangen Substances 0.000 claims description 11
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 10
- 241000202807 Glycyrrhiza Species 0.000 claims description 5
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 241000334160 Isatis Species 0.000 abstract 1
- 241000334154 Isatis tinctoria Species 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 abstract 1
- 229910052602 gypsum Inorganic materials 0.000 abstract 1
- 239000010440 gypsum Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 16
- 238000004519 manufacturing process Methods 0.000 description 9
- 206010011224 Cough Diseases 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 239000003440 toxic substance Substances 0.000 description 7
- 239000000273 veterinary drug Substances 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 238000003756 stirring Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 208000018569 Respiratory Tract disease Diseases 0.000 description 4
- 208000006673 asthma Diseases 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 235000013601 eggs Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010068319 Oropharyngeal pain Diseases 0.000 description 2
- 201000007100 Pharyngitis Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- BITDLWAQPKSXTF-UHFFFAOYSA-M 1-[(3-nitrophenyl)methoxymethyl]pyridin-1-ium;chloride Chemical compound [Cl-].[O-][N+](=O)C1=CC=CC(COC[N+]=2C=CC=CC=2)=C1 BITDLWAQPKSXTF-UHFFFAOYSA-M 0.000 description 1
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 230000036750 egg laying performance Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229960002581 moroxydine hydrochloride Drugs 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicament for treating chicken respiratory diseases, which is powder prepared from the following raw materials (by weight ratio), gypsum 40-65, ephedra 3-15, licorice root 2-10, isatis root 3-12, subprostrate sophora 3-10, common andrographis herb 3-10, dandelion 3-10 and dyers woad leaf 4-12, wherein the components are washed, selected, crushed, mixed, tested, subpackaged and sealed, and stored in cool and dry places.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of respiratory disease of chicken, particularly relate to a kind of medicine of the treatment respiratory disease of chicken of making by herbal composite.
Background technology
The respiratory tract disease is the disease that extensively takes place in the modern poultry husbandry, with cough, get rid of that head, bronchorrhagia, larynx are hemorrhage, to lay eggs less etc. be principal character, this disease is having a strong impact on the growth promoter of chicken, influences the egg laying performance of chicken, causes very big loss to poultry husbandry.At present, the medicine of treatment respiratory disease of chicken is a lot, mainly is chemical synthetic drug, his shortcoming is that Drug resistance is more serious, and specific aim is stronger, and the disease of chicken is complicated sometimes, viral infection and bacterial infection often mix, and chemical synthetic drug curative effect sometimes is not too obvious.And it is residual to exist chemicals in the muscle of chicken and egg.The common use of also useful Chinese herbal medicine and chemicals, as: Henan is " DUKANG GANTAI " of veterinary drug company limited production just in time, main component is Radix Isatidis, Herba Ephedrae, Radix Glycyrrhizae, moroxydine hydrochloride etc., function: the heat clearing away expectorant that looses, relieving cough and asthma, anti-inflammation, antiviral, effective in cure to the chicken and duck respiratory tract disease that various diseases causes, but also have the chemicals residue problem.
Summary of the invention
Task of the present invention provides a kind of drug powder of the treatment respiratory disease of chicken of being made by herbal composite.
Technical scheme of the present invention is: the medicine of treatment respiratory disease of chicken is the powder of being made by following composition weight: (consumption is a weight portion)
Gypsum Fibrosum 40-65 Herba Ephedrae 3-15 Radix Glycyrrhizae 2-10 Radix Isatidis 3-12
Radix Sophorae Tonkinensis 3-10 Herba Andrographis 3-10 Herba Taraxaci 3-10 Folium Isatidis 4-12
Formula optimization weight (part) ratio range that preparation the present invention treats the respiratory disease of chicken medicine is:
Gypsum Fibrosum 50-65 Herba Ephedrae 4-12 Radix Glycyrrhizae 2-7 Radix Isatidis 3-10
Radix Sophorae Tonkinensis 4-7 Herba Andrographis 4-7 Herba Taraxaci 3-9 Folium Isatidis 5-9
Optimum weight (part) proportioning that the present invention treats the medicine of respiratory disease of chicken is:
Gypsum Fibrosum 55 Herba Ephedraes 7 Radix Glycyrrhizaes 4 Radix Isatidis 8
Radix Sophorae Tonkinensis 6 Herba Andrographis 5 Herba Taraxacis 7 Folium Isatidiss 8
Above-mentioned each component is made medicine production method of the present invention is:
(1) the selecting, wash of crude drug: impurity is selected, washs, removed to required Chinese crude drug respectively, in natural temperature or 50 ℃ of following intensive dryings;
(2) pulverizing of crude drug: with pulverizer pulverize separately dried raw material medicine, it is standby to cross 100 sieves;
(3) mix: will required each Chinese medicine by filling a prescription and ormal weight drops in the blender according to this, after stirring,, make water content get final product discharging below 7% 50-60 ℃ of drying 10 hours;
(4) check: test according to every regulation under two appendix powder of " veterinary drug allusion quotation " the nineteen ninety version item;
(5) packing: the product that is up to the standards by the different size packing, pack, put in storage, shady and cool dry place preserves.
The present invention treats the medicine of respiratory disease of chicken, be to carry out on a large amount of actual experiments basis, according to motherland's traditional medicine ancient prescription, learn nosetiology and immunology theory in conjunction with modern popular is sick, through the repeated screening test, plus-minus ancestral side forms, and its cube principle is a heat-clearing and toxic substances removing, smooth throat to stop cough, depressed lung-energy dispersing, anti-inflammation.The pharmacology situation of each component is in the prescription: (1) Gypsum Fibrosum: sweet, hot, cold; Attach to the lung and stomach meridians; Clearing away heat-fire, relieving restlessness are quenched the thirst.(2) Herba Ephedrae: hot, little hardship, temperature; Return lung meridian; The diaphoresis cold expelling should be relievingd asthma inducing diuresis to remove edema by lung.(3) Radix Glycyrrhizae: sweet, flat; GUIXIN, lung, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.(4) Radix Isatidis: bitter, cold; GUIXIN, stomach warp; Heat-clearing and toxic substances removing, the removing heat from blood sore-throat relieving.(5) Radix Sophorae Tonkinensis: bitter, cold; Attach to the lung and stomach meridians; Heat-clearing and toxic substances removing, the detumescence sore-throat relieving.(6) Herba Andrographis: bitter, cold; GUIXIN, lung meridian; Heat-clearing and toxic substances removing, removing heat from blood, detumescence.(7) Herba Taraxaci: bitter, sweet, cold; Return liver, stomach warp; Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.(8) Folium Isatidis: bitter, cold; GUIXIN, stomach warp; Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.
Points for attention:
(1) pulverize: must reach the fineness of regulation, the Chinese medicine powder color and luster is similar, and tangible sign be arranged, and avoids mixing medicine.
(2) notice that control is dried wet, to guarantee abundant mixing.
(3) powder moisture content will be controlled at below 10%, otherwise long time stored perishable.
(4) note the sealing preservation, in case moisture and deteriorate.
Using method: drug powder and the chicken feedstuff that will treat respiratory disease of chicken stir in 3% ratio, feed to chicken, and one day three times, five days courses of treatment, three days can take effect, and can all cure in five days.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further details.
Embodiment 1:
Take by weighing raw material (kilogram) respectively by following proportioning:
Gypsum Fibrosum 55 Herba Ephedraes 7 Radix Glycyrrhizaes 4 Radix Isatidis 8
Radix Sophorae Tonkinensis 6 Herba Andrographis 5 Herba Taraxacis 7 Folium Isatidiss 8
Production method is as follows:
Impurity is selected, washs, removed to required Chinese crude drug respectively, intensive drying under natural temperature; With pulverizer pulverize separately dried raw material medicine, it is standby to cross 100 mesh sieves; Chinese medicine after pulverizing is dropped in the blender according to this by prescription and ormal weight, after stirring,, make water content get final product discharging below 7% 50-60 ℃ of drying 10 hours; Test according to every regulation under two appendix powder of " veterinary drug allusion quotation " the nineteen ninety version item; The product that is up to the standards is by 5 kilogram of one bag hermetic package, warehouse-in, and shady and cool dry place preserves, and is the powder finished product.
Embodiment 2:
Take by weighing raw material (kilogram) respectively by following proportioning, production method is with embodiment 1:
Gypsum Fibrosum 60 Herba Ephedraes 5 Radix Glycyrrhizaes 8 Radix Isatidis 6
Radix Sophorae Tonkinensis 4 Herba Andrographis 8 Herba Taraxacis 4 Folium Isatidiss 5
Embodiment 3:
Take by weighing raw material (kilogram) respectively by following proportioning, production method is with embodiment 1:
Gypsum Fibrosum 45 Herba Ephedraes 13 Radix Glycyrrhizaes 2 Radix Isatidis 3
Radix Sophorae Tonkinensis 9 Herba Andrographis 9 Herba Taraxacis 9 Folium Isatidiss 10
Below be some test situation of the present invention's " medicine of treatment respiratory disease of chicken " powder:
Test one:
Test period: March 5 calendar year 2001
Test site: Shan County, Henan Province Zhang Maoxiang swells luxuriant plant
Experimental animal: commodity egg
Test objective: the practical application drug effect of checking " medicine of treatment respiratory disease of chicken " powder.
The contrast medicine: Henan is " DUKANG GANTAI " of veterinary drug company limited production just in time.
The fowl disease situation: 4328 of chicken groups cough, asthma, stream nose occur, get rid of head, noise made in coughing or vomiting goes out mucus or clot, and the degradation symptom is diagnosed as respiratory tract disease under the laying rate.
Divide two groups of tests:
2016 of test group stir drug powder of the present invention and chicken feedstuff in 3% ratio, feed to chicken, and one day three times,, first day, sx obviously took a turn for the better in second day, and the 3rd day, the basic healing continued to feed and all cured to the 5th day, do not have dead.
2312 of matched groups, just in time " DUKANG GANTAI " of veterinary drug company limited production of Henan of feeding, one to three day, sx was not obvious, indivedual sxs, five to seven days, most sxs, eight to ten days, be clearly better basic healing the to the 13 day, dead 26, mortality rate 1.1%.
Test two:
Test period: June 15 calendar year 2001
Test site: chicken farm, Zhang Maoxiang station, Shan County, Henan Province
Experimental animal: breed chicken
Test objective: the practical application drug effect of checking " medicine of treatment respiratory disease of chicken " powder.
The contrast medicine: Henan is " DUKANG GANTAI " of veterinary drug company limited production just in time.
The fowl disease situation: cough, asthma, stream nose appear in 3654 of chicken groups, get rid of head, feather pine symptom such as disorderly, is diagnosed as respiratory tract disease.
Divide two groups of tests:
2275 of test group stir drug powder of the present invention and chicken feedstuff in 3% ratio, feed to chicken, one day three times,, first day, sx, indivedual sxs obviously took a turn for the better the 3rd day in second day, the basic healing, continue to feed and all cured to the 5th day, dead 2, mortality rate 0.09%.
1379 of matched groups, just in time " DUKANG GANTAI " of veterinary drug company limited production of Henan of feeding, one to three day, sx was not obvious, indivedual sxs, five to seven days, sx, eight to ten days, be clearly better basic healing the to the 13 day, dead 18, mortality rate 1.3%.
From calendar year 2001 to 2003 year, use medicine of the present invention in 3 years, 150,000 6 over thousands of of treatment respiratory disease of chicken, cure rate 97.6%, effective percentage reaches 98.8%.
Claims (3)
1, a kind of medicine for the treatment of respiratory disease of chicken is characterized in that it is the powder of being made by the following weight proportion raw material
Gypsum Fibrosum 40-65 Herba Ephedrae 3-15 Radix Glycyrrhizae 2-10 Radix Isatidis 3-12
Radix Sophorae Tonkinensis 3-10 Herba Andrographis 3-10 Herba Taraxaci 3-10 Folium Isatidis 4-12
2, the medicine of treatment respiratory disease of chicken according to claim 1 is characterized in that wherein the weight proportion of each raw material is
Gypsum Fibrosum 50-65 Herba Ephedrae 4-12 Radix Glycyrrhizae 2-7 Radix Isatidis 3-10
Radix Sophorae Tonkinensis 4-7 Herba Andrographis 4-7 Herba Taraxaci 3-9 Folium Isatidis 5-9
3, the medicine of treatment respiratory disease of chicken according to claim 1 is characterized in that wherein the weight proportion of each raw material is
Gypsum Fibrosum 55 Herba Ephedraes 7 Radix Glycyrrhizaes 4 Radix Isatidis 8
Radix Sophorae Tonkinensis 6 Herba Andrographis 5 Herba Taraxacis 7 Folium Isatidiss 8
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410010116 CN1283273C (en) | 2004-03-08 | 2004-03-08 | Medicine for treating chicken respiratory diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410010116 CN1283273C (en) | 2004-03-08 | 2004-03-08 | Medicine for treating chicken respiratory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1666760A true CN1666760A (en) | 2005-09-14 |
| CN1283273C CN1283273C (en) | 2006-11-08 |
Family
ID=35038143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410010116 Expired - Fee Related CN1283273C (en) | 2004-03-08 | 2004-03-08 | Medicine for treating chicken respiratory diseases |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1283273C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1811940A4 (en) * | 2004-10-27 | 2009-12-02 | Sk Chemicals Co Ltd | Sophorae subprostratae radix extract for prevention and treatment of respiratory diseases |
| CN102217734A (en) * | 2011-06-15 | 2011-10-19 | 北京联合大学生物化学工程学院 | Preparation method of chicken feed additive |
| CN103583808A (en) * | 2013-11-21 | 2014-02-19 | 史占彪 | Preparation method of beverage concentrated solution capable of preventing chicken bird flu, helping digestion and strengthening physique |
| CN104186969A (en) * | 2014-07-29 | 2014-12-10 | 合肥德邦动物保健有限公司 | Preparation method of chicken feed additive containing chitosan |
-
2004
- 2004-03-08 CN CN 200410010116 patent/CN1283273C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1811940A4 (en) * | 2004-10-27 | 2009-12-02 | Sk Chemicals Co Ltd | Sophorae subprostratae radix extract for prevention and treatment of respiratory diseases |
| CN102217734A (en) * | 2011-06-15 | 2011-10-19 | 北京联合大学生物化学工程学院 | Preparation method of chicken feed additive |
| CN102217734B (en) * | 2011-06-15 | 2013-04-10 | 北京联合大学生物化学工程学院 | Preparation method of chicken feed additive |
| CN103583808A (en) * | 2013-11-21 | 2014-02-19 | 史占彪 | Preparation method of beverage concentrated solution capable of preventing chicken bird flu, helping digestion and strengthening physique |
| CN104186969A (en) * | 2014-07-29 | 2014-12-10 | 合肥德邦动物保健有限公司 | Preparation method of chicken feed additive containing chitosan |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1283273C (en) | 2006-11-08 |
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Granted publication date: 20061108 |