CN109394884A - The Chinese medicine composition and preparation method thereof for treating white diarrhea - Google Patents
The Chinese medicine composition and preparation method thereof for treating white diarrhea Download PDFInfo
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- CN109394884A CN109394884A CN201811629233.2A CN201811629233A CN109394884A CN 109394884 A CN109394884 A CN 109394884A CN 201811629233 A CN201811629233 A CN 201811629233A CN 109394884 A CN109394884 A CN 109394884A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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Abstract
The present invention relates to a kind of Chinese medicine composition and preparation method thereof for treating white diarrhea, the component and its weight fraction ratio of the Chinese medicine composition are respectively as follows: 5-15 parts of Herba Andrographitis；5-15 parts of Rhizoma Atractylodis Macrocephalae；5-10 parts of Radix Sanguisorbae preparata；5-15 parts of Radix Astragali；5-10 parts of the Chinese bulbul；5-15 parts of radix scutellariae；5-10 parts of dandelion；5-10 parts of Cortex Phellodendri；10-20 parts of Radix Glycyrrhizae.The present invention has effects that antibacterial anti-inflammatory, moisturizing antidiarrheal, has no toxic side effect, and drug residue free is not likely to produce drug resistance, the requirement for meeting safe veterinary drug, ensureing animal-derived food safety, is a kind of Chinese medicine composition of ideal treatment white diarrhea.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition and preparation method thereof for treating white diarrhea.
Background technique
White diarrhea is the communicable disease as caused by S. pullonum, there is generation all over the world, is harm poultry
One of the disease of industry most serious.The disease is a kind of extremely common infectious disease, is caused by Salmonella pullon, excreta
It is important communication media, while egg vertical transmission can also be passed through.Cardinal symptom and lesion are that feed is not eaten in chick performance, are afraid of
Cold, body is rolled up, and wing is sagging, and spiritual depressed or lethargic sleep, arranges thick white or yellowish, light green loose stools, anus are sometimes hard
The excrement block of knot is closed, expiratory dyspnea.For Adult Chicken without clinical symptoms, the serious diseased chicken performance of minority infection is apathetic, arranges yellowish green
Color or egg white sample loose stools, the visible liver of major lesions, spleen enlargement, fragility have downright bad point, and kidney is dark red congested or pale poor
Often there is peritonitis variation in blood.The visible ovarian atrophy of laying hen, ovum denaturation, diseased chicken are laid eggs stopping.
Currently, antibacterials application be still treatment important means, but with antibiotic, sulfa drugs it is long-term
Using and feed in add for a long time, keep the drug resistance of Salmonella pullon all the more serious.In addition to this, white diarrhea sramana
Family name bacillus can be colonized in chicken intestinal, pollute chicken, subsequently into human foods chain, become the infection of mankind's Salmonella
Potential source.Therefore, seek to prevent and treat bacteriosis good effect and the non-harmful drugs such as white diarrhea, obtain safe poultry and produce
Product are increasingly taken seriously.
Summary of the invention
The present invention has effects that antibacterial anti-inflammatory, moisturizing antidiarrheal, has no toxic side effect, and drug residue free is not likely to produce drug resistance
Property, the requirement for meeting safe veterinary drug, ensureing animal-derived food safety is a kind of Chinese medicine composition of ideal treatment white diarrhea.
It is another object of the present invention to provide a kind of preparation methods of Chinese medicine composition for treating white diarrhea.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition for treating white diarrhea, the component and its weight fraction ratio of Chinese medicine composition are respectively as follows:
5-15 parts of Herba Andrographitis；
5-15 parts of Rhizoma Atractylodis Macrocephalae；
5-10 parts of Radix Sanguisorbae preparata；
5-15 parts of Radix Astragali；
5-10 parts of the Chinese bulbul；
5-15 parts of radix scutellariae；
5-10 parts of dandelion；
5-10 parts of Cortex Phellodendri；
10-20 parts of Radix Glycyrrhizae.
A kind of the step of preparation method of Chinese medicine composition that treating white diarrhea, preparation method, is as follows:
(1) Herba Andrographitis, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Huang are weighed respectively according to the weight ratio
Cypress, Radix Glycyrrhizae are ground into powder, and all lead to sieve with 100 mesh sieve respectively；
(2) by Herba Andrographitis, the Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Huang after sieving in step (1)
Cypress, Radix Glycyrrhizae are put into blending tank, are sufficiently mixed uniformly to get the Chinese medicine composition finished product for arriving treatment white diarrhea.
The invention has the advantages and beneficial effects that:
1, Herba Andrographitis, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, the Huang contained in the Chinese medicine composition of this treatment white diarrhea
A kind of reed mentioned in ancient books, dandelion, Cortex Phellodendri, traditional Chinese medicine of licorice root composition have good preventive and therapeutic effect to white diarrhea caused by Salmonella pullon,
Antibacterial action effect is obvious.
2, the Chinese medicine composition has a broad antifungal spectrum of this treatment white diarrhea, effect is obvious, and quality is stablized, not by temperature and pH value
It influences, it is easy to use, it easily absorbs, blood peak concentration of drug can be reached with extremely low concentration in the short period.
3, the present invention has effects that antibacterial anti-inflammatory, moisturizing antidiarrheal, has no toxic side effect, drug residue free is not likely to produce resistance to
Pharmacological property, the requirement for meeting safe veterinary drug, ensureing animal-derived food safety are a kind of Chinese traditional medicine compositions of ideal treatment white diarrhea
Object.
Specific embodiment
The present invention is described in further detail by following embodiment.It should be understood that following embodiments be it is illustrative, be not
It is limited, it cannot be limited the scope of protection of the present invention with following embodiments.
Herba Andrographitis according to the present invention, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Cortex Phellodendri, Radix Glycyrrhizae are equal
It can be commercially available on the market.
Embodiment 1
A kind of Chinese medicine composition for treating white diarrhea, the component and its weight of Chinese medicine composition be respectively as follows: Herba Andrographitis 5g,
Rhizoma Atractylodis Macrocephalae 5g, Radix Sanguisorbae preparata 5g, Radix Astragali 5g, Chinese bulbul 5g, radix scutellariae 5g, dandelion 5g, Cortex Phellodendri 5g, Radix Glycyrrhizae 10g.
A kind of the step of preparation method of Chinese medicine composition that treating treatment white diarrhea, preparation method, is as follows:
(1) Herba Andrographitis, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Huang are weighed respectively according to the weight ratio
Cypress, Radix Glycyrrhizae are ground into powder, and all lead to sieve with 100 mesh sieve respectively；
(2) by Herba Andrographitis, the Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Huang after sieving in step (1)
Cypress, Radix Glycyrrhizae are put into blending tank, are sufficiently mixed uniformly to get the Chinese medicine composition finished product for arriving treatment white diarrhea.
Embodiment 2
A kind of Chinese medicine composition for treating white diarrhea, the component and its weight of Chinese medicine composition are respectively as follows: Herba Andrographitis
15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Sanguisorbae preparata 10g, Radix Astragali 15g, Chinese bulbul 10g, radix scutellariae 15g, dandelion 10g, Cortex Phellodendri 10g, Radix Glycyrrhizae 20g.
The step of preparation method, is the same as embodiment 1.
Embodiment 3
A kind of Chinese medicine composition for treating white diarrhea, the component and its weight of Chinese medicine composition are respectively as follows: Herba Andrographitis
10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Sanguisorbae preparata 8g, Radix Astragali 10g, Chinese bulbul 8g, radix scutellariae 10g, dandelion 8g, Cortex Phellodendri 8g, Radix Glycyrrhizae 15g.
The step of preparation method, is the same as embodiment 1.
Pharmacodynamic test
1, experimental animal
Experimental animal is the chicken house that white diarrhea occurs for Weifang City, Shandong Province, and illness rate is up to 50% or more.
2, test grouping
The Growing Chicken with white diarrhea clinical symptoms is chosen in chicken house, and is randomly divided into 5 groups, every group 200.
1 group is tested as control group, is not processed；
2 groups are tested as low dose group of the present invention, 1/2 times of amount of clinical recommended dose (per kilogram of body weight 1g) is administered, spice,
Successive administration 3 days.
3 groups are tested as middle dose group of the present invention, clinical recommended dose (per kilogram of body weight 2g) is administered, spice, successive administration 3
It.
4 groups are tested as high dose group of the present invention, 2 times of amounts of clinical recommended dose (per kilogram of body weight 4g) are administered, spice, even
Continuous administration 3 days.
5 groups are tested as terramycin control group, is used to specifications, successive administration 3 days.
3, test result
To the chicken group of infection white diarrhea, give the traditional chinese medicine composition of the invention of various dose respectively, after spice, by with it is right
It is compared according to group, the clinical symptoms of morbidity chicken group are substantially reduced, and feed conversion rate rises.The therapeutic effect and feeding of middle dose group
Material conversion ratio has all reached ideal requirement；Terramycin control group therapeutic effect is ideal, but feed conversion rate is obviously not so good as
The present invention.It the results are shown in Table 1.
1 observation of curative effect of table
4, conclusion and analysis
It is analyzed in terms of clinical symptoms, dissect variation, the conversion ratio of feed, cure rate four, middle dose group and height
The therapeutic effect of dosage group is apparently higher than other treatment group, wherein the control efficiency with middle dose group is best.Control group has centainly
Therapeutic effect, but the feed conversion rate of chicken is affected after treatment, and it is larger to suffer economic loss.
Claims (2)
1. a kind of Chinese medicine composition for treating white diarrhea, it is characterised in that: the component and its weight fraction ratio of the Chinese medicine composition
It is respectively as follows:
5-15 parts of Herba Andrographitis；
5-15 parts of Rhizoma Atractylodis Macrocephalae；
5-10 parts of Radix Sanguisorbae preparata；
5-15 parts of Radix Astragali；
5-10 parts of the Chinese bulbul；
5-15 parts of radix scutellariae；
5-10 parts of dandelion；
5-10 parts of Cortex Phellodendri；
10-20 parts of Radix Glycyrrhizae.
2. a kind of preparation method of the Chinese medicine composition for the treatment of white diarrhea as described in claim 1, it is characterised in that: the preparation
The step of method, is as follows:
(1) Herba Andrographitis, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Cortex Phellodendri, sweet is weighed respectively according to the weight ratio
Grass meal is broken into powder, and all leads to sieve with 100 mesh sieve respectively；
(2) by the Herba Andrographitis, Rhizoma Atractylodis Macrocephalae, Radix Sanguisorbae preparata, Radix Astragali, the Chinese bulbul, radix scutellariae, dandelion, Cortex Phellodendri, sweet after sieving in step (1)
Grass is put into blending tank, is sufficiently mixed uniformly to get the Chinese medicine composition finished product for arriving treatment white diarrhea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201811629233.2A CN109394884A (en) | 2018-12-28 | 2018-12-28 | The Chinese medicine composition and preparation method thereof for treating white diarrhea |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811629233.2A CN109394884A (en) | 2018-12-28 | 2018-12-28 | The Chinese medicine composition and preparation method thereof for treating white diarrhea |
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| Publication Number | Publication Date |
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| CN109394884A true CN109394884A (en) | 2019-03-01 |
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ID=65461899
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| CN201811629233.2A Withdrawn CN109394884A (en) | 2018-12-28 | 2018-12-28 | The Chinese medicine composition and preparation method thereof for treating white diarrhea |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112451589A (en) * | 2020-12-18 | 2021-03-09 | 河南科技大学 | Pharmaceutical composition for treating pullorum disease and preparation method thereof |
-
2018
- 2018-12-28 CN CN201811629233.2A patent/CN109394884A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112451589A (en) * | 2020-12-18 | 2021-03-09 | 河南科技大学 | Pharmaceutical composition for treating pullorum disease and preparation method thereof |
| CN112451589B (en) * | 2020-12-18 | 2022-05-27 | 河南科技大学 | Pharmaceutical composition for treating pullorum disease and preparation method thereof |
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Application publication date: 20190301 |