CN1660226A - 'Wuzi Mingmu' pill and preparing technique - Google Patents

Abstract

A Chinese medicine in the form of honeyed pills for treating pseudomyopia, high-degree myopia, visual fatigue, etc is prepared from 16 Chinese-medicinal materials including wolfberry fruit, dodder seed, lucid ligustrum fruit, etc.

Description

'Wuzi Mingmu ' pill and preparation technology thereof

Affiliated technical field

'Wuzi Mingmu ' pill of the present invention and preparation technology thereof belong to medicine and the preparation technology thereof who treats ophthalmic, relate in particular to Chinese medicine preparation and preparation technology thereof with Chinese prescription treatment juvenile myopia.

Background technology

Because the adolescents with learning task is heavy, among the student pseudomyopia and in, the high myopic eye patient all increases and do not subtract every year, the treatment ophthalmic medicine that existing market is sold is many with the treatment glaucoma, trachoma, herpetic ophthalmia, sympathetic ophthalmia, conjunctivitis, viral oculopathy such as keratitis and the outer infection of eye disease are main, the treatment juvenile myopia only has the cod-liver oil soft gelatin capsule, fish oil soft gelatin capsule etc. is rich in the bathypelagic fish oil preparation of eicosapentaenoic acid and docosahexenoic acid, but modern medicine confirms, this type of nourishes the easy oxidation of medicament and putrid and deteriorated, the antioxidant preservative consumption is very high in the preparation, take for a long time and can produce free radical increase and the high side effect of cholesterol, influence the teenager health and grow up.Market lacks the treatment teenage pseudomyopia that has no side effect and the Chinese patent drug of middle and high degree myopia.

Summary of the invention

The objective of the invention is: give the teenager suffer from pseudomyopia and middle and high degree myopia ophthalmic provide scientific formulation, monarch compatibility proper, can reach nourishing the liver to improve visual acuity, invigorating the spleen and replenishing QI, sensible, the promoting blood circulation to remove obstruction in the collateral of nourishing kidney, effectively treat the compound Chinese medicinal preparation of pseudomyopia and middle and high degree myopia, and have no side effect, evident in efficacy, with low cost, production technology is easy.

To achieve these goals, the technical solution adopted in the present invention is: 'Wuzi Mingmu ' pill according to pseudomyopia and in, the main etiology and pathogenesis of high myopia, with nourishing the liver, nourishing kidney, QI invigorating, collateral dredging is a principle of treatment, and the crude drug total amount is 214 grams in the prescription, by Fructus Lycii 16 grams, Semen Cuscutae 16 grams, Fructus Ligustri Lucidi 16 grams, Fructus Broussonetiae 16 grams, Fructus Leonuri 16 grams, Flos Chrysanthemi 16 grams, Radix Codonopsis 16 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Radix Glycyrrhizae Preparata 5 grams, Radix Rehmanniae Preparata 10 grams, Radix Polygoni Multiflori Preparata 10 grams, Rhizoma Acori Graminei 10 grams, close Radix Polygalae 5 grams, Rhizoma Chuanxiong 10 grams, Radix Salviae Miltiorrhizae 16 grams and proper honey are formed.The preparation technology of preparation 'Wuzi Mingmu ' pill is divided into five kinds of Chinese medicine powder process, ten Herba indigoferae Pseudotinctoriae decoct, puddle honeyed pill three road technologies, getting Radix Codonopsis, the Radix Astragali, Rhizoma Acori Graminei, Radix Salviae Miltiorrhizae, honey polygala root Chinese medicine of the five flavours material earlier pulverized 80 mesh sieves and becomes the fine powder medicine standby, get again all the other ten simply Chinese herbal medicine add 8 times of water gagings at every turn and decoct 2 times, decocting time was respectively 2 hours, 1.5 hours, collecting decoction filters, filtrate decompression is concentrated into the clear paste that relative density is 1.22-1.25 (80 ℃), at last with standby fine powder medicine and clear paste mixing, add an amount of Mel, make water-honeyed pill, get patent medicine after 60 ℃ of dryings.Chinese medicine thinks that the vital organs of the human body, QI and blood seminal fluid, the twelve regular channels are all relevant in eyes, so-called " the essence of five ZANG-organs and six FU-organs gas; annotate all in order and eyeball for it ", " all arteries and veins persons; all belong to order ", " order person; smart feeling pulse gather also ", in the TCM Ophthalmology document, pseudomyopia and in, antimetropia etc. is referred to as " can be near timid far away ", " myopia ", " look closely timid far " etc., liver,spleen,kidney void due to the pathogenesis that gets to the bottom of sb.'s illness, the elder generation's factor day after tomorrow of returning or deficiency of vital energy damage of essence more can not on annotate in order and form disease.Modern Chinese medicine research confirms: in the 'Wuzi Mingmu ' pill prescription, Fructus Lycii nourishing the liver, nourishing kidney, lung moistening cure mainly caused by liver and kidney deficiency, have a dizzy spell, and be visual unclear; Semen Cuscutae the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity cure mainly blurred vision tinnitus; Fructus Ligustri Lucidi liver and kidney tonifying, clearind deficient heat, make eye bright, cure mainly Light-headedness, poor vision; Fructus Broussonetiae nourishing kidney tonifying YIN, liver heat removing and eyesight improving, invigorating spleen for diuresis cure mainly blurred vision, corneal nebula, the soft pain of waist knee joint; Fructus Leonuri promoting blood flow to regulate menstruation, liver heat removing and eyesight improving cure mainly conjunctival congestion and swelling pain, the living cataracta of order; Flos Chrysanthemi wind and heat dispersing, suppressing the hyperactive liver make eye bright, analgesic detumescence, cure mainly conjunctival congestion and swelling pain; Radix Codonopsis strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid cure mainly weakness of the spleen and stomach, limbs fatigue, deficiency of both QI and blood; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic cure mainly deficiency-weakness of spleen-QI, spiritlessness and weakness, dizziness due to fluid-retention; Radix Glycyrrhizae Preparata QI invigorating tonifying liver, relieving spasm to stop pain, clearing away lung-heat to relieve cough, the quiet poison of pathogenic fire purging, coordinating the actions of various ingredients in a prescription cure mainly asthenia lack of appetite, emaciated look; Enrich blood YIN nourishing, beneficial essence of Radix Rehmanniae Preparata filled out marrow, cures mainly Hiccough and deaf, the head is dim-sighted; Radix Polygoni Multiflori Preparata nourishing the blood and yin, loosening bowel to relieve constipation, the detoxifcation of dispeling the wind cure mainly blood deficiency Light-headedness, cardiopalmus, insomnia; Rhizoma Acori Graminei waking up the patient from unconsciousness by dissipating phlegm, removing dampness circulation of qi promoting, reducing swelling and alleviating pain cure mainly calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness; The honey polygala root mind tranquilizing and the heart calming, eliminate the phlegm have one's ideas straightened out, removing toxic substances and promoting subsidence of swelling, cure mainly irritability, palpitation with fear insomnia, forgetful; The Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping cures mainly dizzy, the anemofrigid-damp arthralgia of headache, costa sternales pain; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind cure mainly heat and go into nutrient blood, dysphoria, vexed insomnia.Select above-mentioned prescription medicine compatibility for use, it is the etiology and pathogenesis of ophthalmic due to the excess eye-using such as, ophthalmic bloated painful according to teenage pseudomyopia and middle and high degree myopia, asthenopia, eye,, promoting blood circulation to remove obstruction in the collateral sensible with nourishing the liver to improve visual acuity, invigorating the spleen and replenishing QI, nourishing kidney is principle of treatment, so be monarch drug with Fructus Lycii, Semen Cuscutae nourishing the liver to improve visual acuity; Fructus Ligustri Lucidi, Fructus Broussonetiae, Fructus Leonuri, Flos Chrysanthemi are ministerial drug, the principal drug assistance nourishing the liver to improve visual acuity; Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata invigorating the spleen and replenishing QI, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Rhizoma Acori Graminei, the honey polygala root nourishing kidney is sensible is adjuvant drug altogether; Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae altogether for the messenger drug promoting blood circulation to remove obstruction in the collateral, draw the through sick institute of many medicines, play altogether that nourishing the liver to improve visual acuity, invigorating the spleen and replenishing QI, nourishing kidney are sensible, the merit of promoting blood circulation to remove obstruction in the collateral, treating both the principal and secondary aspects of a disease effectively improves the uncomfortable symptom of eye due to the excess eye-usings such as teenage pseudomyopia and middle and high degree myopia and asthenopia, eye are painful, ophthalmic bloated.

'Wuzi Mingmu ' pill cures mainly relevant Pharmacodynamic test of active extract with function and confirms in preclinical study: 'Wuzi Mingmu ' pill has the obvious suppression effect to eye conjunctivitis, the effect of analgesia platycoria is strong, can directly produce relaxation effect, and contraction there is tangible antagonism to pipe smooth muscle to pipe smooth muscle.Recommending clinical Coming-of-Age Day consumption is 3.0 grams; Oral; 6 weeks of continuous use are a course of treatment.

The invention has the beneficial effects as follows: prescription monarch compatibility is reasonable, by the effective ingredient complementation, 'Wuzi Mingmu ' pill has nourishing the liver to improve visual acuity, invigorating the spleen and replenishing QI, sensible, the promoting blood circulation to remove obstruction in the collateral effect of taste bone, can effectively treat pseudomyopia and middle and high degree myopia, and have no side effect, evident in efficacy, easy, the low production cost of production technology, it is simultaneously effective in cure that excess eye-usings such as painful to asthenopia, eye simultaneously, ophthalmic bloated cause the uncomfortable disease of eye.

The specific embodiment

1, the 'Wuzi Mingmu ' pill prescription is made up of ten Six-element Chinese herbal medicine and Mel, wherein Fructus Lycii 16 restrains, Semen Cuscutae 16 grams, Fructus Ligustri Lucidi 16 grams, Fructus Broussonetiae 16 grams, Fructus Leonuri 16 grams, Flos Chrysanthemi 16 grams, Radix Codonopsis 16 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Radix Glycyrrhizae Preparata 5 grams, Radix Rehmanniae Preparata 10 grams, Radix Polygoni Multiflori Preparata 10 grams, Rhizoma Acori Graminei 10 grams, honey polygala root 5 grams, Rhizoma Chuanxiong 10 grams, Radix Salviae Miltiorrhizae 16 gram and proper honey, wherein with Radix Glycyrrhizae, Radix Polygoni Multiflori, the Radix Polygalae decoction pieces is concocted into Radix Glycyrrhizae Preparata with traditional method, Radix Polygoni Multiflori Preparata, weighing is standby respectively behind the honey polygala root, it is standby that Mel is refined into water honey, and weighing is standby respectively behind all the other Chinese herbal medicine enchashment row prepared slices of Chinese crude drugs roguing well sifteds.

2, 'Wuzi Mingmu ' pill preparation technology

(1) getting Radix Codonopsis, the Radix Astragali, Rhizoma Acori Graminei, Radix Salviae Miltiorrhizae, honey polygala root Chinese medicine of the five flavours material pulverized 80 mesh sieves and becomes the fine powder medicine standby.

(2) get all the other 11 flavor Chinese herbal medicine and add 8 times of water gagings decoctions 2 times at every turn, decocted 2 hours for the first time, 1.5 hours for the second time, collecting decoction filtered, and filtrate decompression is concentrated into the clear paste that relative density is 1.22-1.25 (80 ℃).

(3) with puddling evenly in the standby fine powder adding clear paste, add the suitable quantity of water processed with honey and become water-honeyed pill, get patent medicine after 60 ℃ of dryings.

Claims (2)

1, a kind of 'Wuzi Mingmu ' pill is characterized in that the crude drug total amount is 214 grams, is made up of Fructus Lycii 16 grams, Fructus Ligustri Lucidi 16 grams, Semen Cuscutae 16 grams, Fructus Broussonetiae 16 grams, Fructus Leonuri 16 grams, Flos Chrysanthemi 16 grams, Radix Codonopsis 16 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Radix Glycyrrhizae Preparata 5 grams, Radix Rehmanniae Preparata 10 grams, Radix Polygoni Multiflori Preparata 10 grams, Rhizoma Acori Graminei 10 grams, close Radix Polygalae 5 grams, Rhizoma Chuanxiong 10 grams, Radix Salviae Miltiorrhizae 16 grams and proper honey in the prescription.

2, 'Wuzi Mingmu ' pill preparation technology according to claim 1, it is characterized in that getting earlier Radix Codonopsis, the Radix Astragali, Rhizoma Acori Graminei, Radix Salviae Miltiorrhizae, honey polygala root Chinese medicine of the five flavours material pulverized 80 mesh sieves and becomes the fine powder medicine standby, get again all the other ten simply Chinese herbal medicine add 8 times of water gagings at every turn and decoct 2 times, decocting time was respectively 2 hours, 1.5 hours, collecting decoction filters, filtrate decompression is concentrated into the clear paste that relative density is 1.22-1.25 (80 ℃), at last with standby fine powder medicine and clear paste mixing, add an amount of Mel, make water-honeyed pill, get patent medicine after 60 ℃ of dryings.