CN105030999A - Traditional Chinese medicine for treating sympathetic ophthalmia - Google Patents
Traditional Chinese medicine for treating sympathetic ophthalmia Download PDFInfo
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- CN105030999A CN105030999A CN201510527517.0A CN201510527517A CN105030999A CN 105030999 A CN105030999 A CN 105030999A CN 201510527517 A CN201510527517 A CN 201510527517A CN 105030999 A CN105030999 A CN 105030999A
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Abstract
The invention relates to a traditional Chinese medicine for treating sympathetic ophthalmia. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 5 parts of white grubs, 6 parts of sibirica walking fern herbs, 15 parts of horseweed fleabane herbs, 9 parts of limnophila sessiliflora, 9 parts of west Szechwan pyrethrum flowers, 4 parts of delavay stephania roots, 15 parts of murdannia loriformis and 30 parts of schizonepeta spikes. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating sympathetic ophthalmia.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of sympathetic ophthalmia.
Background technology
After sympathetic ophthalmia refers to and occurs chronic or subacute apyetous uveitis after boring wound or intraocular surgery occur a branch hole, also there is the reaction of ejusdem generis tunica uvea in another branch hole (normal eyes), is called sympathetic ophthalmia.Injured eye is called exciting eye, and opposite side is good for eye and is called sympathizing eye.After usually occurring in perforating injury of eyeball, after also can occurring in intraocular surgery, eyeball contusion and intraocular malignant melanoma also can occur sometimes.The traditional Chinese medical science is called: iridocyclitis, chronic iridocyclitis, blurring of vission, micropsia, firefly star meets the eye on every side, and it is different that sympathetic ophthalmia occurs according to inflammation the symptom that the anterior or rear portion of the film that swings causes, and roughly belongs to (anterior tunica uvea is main) " iridocyclitis ", " chronic iridocyclitis "; (rear portion tunica uvea is main) category such as " blurring of vission ", " micropsia ", " firefly star meets the eye on every side ".This disease is many because of patient's innate deficiency, and the positive deficiency of vital energy declines, and when at a glance by after penetrating wound or intraocular surgery, malicious heresy is taken advantage of a weak point, and cause local qi depression to blood stasis, hold back Yu Huare, heat is tied mutually with poison heresy, on violate in order, with the passing of time impairment of YIN, the phase there will be the sign of hyperactivity of fire caused by deficiency of YIN after being ill.
Medical material present Research involved in the present invention is as follows:
Holotrichia diomphalia Bates [another name] Ben, Ben Qi, answer that bar, Stachys geobombycis C. Y. Wu, Fei are neat, breast is neat, grub, one's old mother worm, holotrichia.[source] medical material Ji Yuan: be the larva of the electric and nearly edge animal of Melolonthidae animal northeast large black gill disease gold.Gather and store: turning over scholar between the 5-8 month and catch, clean, scalding with boiling water dead, dry or dry.[nature and flavor] salty in the mouth; Slightly warm in nature.[return through] Liver Channel.[function cures mainly] removing blood stasis with potent drugs; Eliminating stagnation; Pain relieving; Removing toxic substances.Main blood stasis amenorrhea, lump in the abdomen; Injured stasis of blood pain; Gout; Tetanus; Sore throat; Carbuncle; Erysipelas.[usage and dosage] takes orally: decoct soup, 2 ~ 5g.[attention] weakling and anemia of pregnant woman prohibit clothes.[extracts] " China's book on Chinese herbal medicine ".
Herba Camptosori Sibirici [another name] gap bridge grass, Radix Rhodiolae Yunnanensis, Pyrrosia assimilis(Bak.) Ching.[source] medical material Ji Yuan: be the herb of Aspleniaceae plant walking fern.Gather and store: summer, autumn gather, cleaning, dry.[nature and flavor] are light; Flat.[return through] heart channel.[function cures mainly] blood circulation promoting and blood stasis dispelling; Hemostasis; Removing toxic substances.Main thromboangiitis obliterans; Hemiplegia; Metrorrhagia; Traumatic hemorrhage; Neurodermatitis; Ulcer of the lower limb.[usage and dosage] takes orally: decoct soup, 3 ~ 6g.[extracts] " China's book on Chinese herbal medicine ".
Herba Erigerontis Canadensis (Herba Conyzae Canadensis) [another name] Herba Hedyotidis Diffusae, Folium Bambusae Chinese mugwort, Herba Swertiae davidi, Herba Acroptili repentis.[source] is the herb of feverfew Conyza canadensis (L.) Cronq..[nature and flavor] are bitter, cool.[function cures mainly] heat clearing away, removing toxic substances, dispelling wind for relieving itching.Control stomatitis, otitis media, eye conjunctivitis, acute toothache, rheumatic ostalgia.[usage and dosage] takes orally: decoct soup, 15 ~ 25g.[extracts] " China's book on Chinese herbal medicine ".
Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. [source] medical material Ji Yuan: be the herb of goatweed Herba Limnophilae sessiliflorae.Gather and store: spring, summer gather, drying or using fresh herb.[nature and flavor] bitter in the mouth; It is cold in nature..[function cures mainly] subduing swelling and detoxicating; Parasite killing delousing.Main burn and scald; Furuncle toxic swelling; Head louse.[usage and dosage] takes orally: decoct soup, 6 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Flos Pyrethri tatsienensis [another name] monarch Se Er wood U.S. is many.[source] is the head inflorescence of feverfew Flos Pyrethri tatsienensis.8 ~ JIUYUE is picked flowers, and dries in the shade.[nature and flavor] are cold in nature, bitter in the mouth.[function cures mainly] invigorates blood circulation, damp eliminating, antiinflammatory, pain relieving.Control traumatic injury, damp-heat syndrome.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Radix Stephaniae Epigaeae [another name] Stephania cepharatha Hayata, DIWUGUI, white Herba Sonerilae cantonensis, Folium Nelumbinis secretly disappear.[source] is Menispermaceae stephania plant Radix Stephaniae Epigaeae, is used as medicine with tuber.The four seasons all can adopt, and to adopt autumn as good, clean section, dry use.Or boil 2 hours, peeling is dried, and levigation is for subsequent use.[nature and flavor] are bitter, cold.[return through] returns stomach warp.[function cures mainly] heat-clearing and toxic substances removing, dampness removing, pain relieving.For stomachache, stomachache, acute gastroenteritis, rheumatic arthritis, malaria; Carbuncle furuncle and phyma poison is controlled in external, eczema.[usage and dosage] 1 ~ 2 money [usage and dosage] is for oral administration: decoct soup, 2 ~ 4g.[attention] anemia of pregnant woman and weakling avoid clothes.Consumption is crossed conference and is caused vomiting.[extracts] " China's book on Chinese herbal medicine ".
Yoke grass [another name] red Rhizoma Imperatae, blue flower.[source] medical material Ji Yuan: be the herb of Commelianaceae plant narrow leaf Phyllostachys congesta grass.Gather and store: summer, autumn gather, cleaning, dry or using fresh herb.[nature and flavor] are sweet; Light; Micro-hardship; Cold.[return through] returns Liver and kidney two warp.[function cures mainly] clearing and antitussive; Removing toxic substances; Diuresis.Main infantile hyperpyrexia; Cough due to lung-heat; Conjunctival congestion and swelling pain; Hematodiarrhoea; Sore and toxic; Pyretic stranguria; Dysuria.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Herba Schizonepetae [another name] fragrant Schizonepeta tenuifolia Briq, line shepherd's purse, Herba Schizonepetae, false Soviet Union.[source] this product is the dry aerial parts of labiate Herba Schizonepetae.Summer, season in autumn two, the flowers are in blossom to top, fringe green time tap, removing impurity, dry.[nature and flavor] are pungent, tepor.[return through] returns lung, Liver Channel.[function cures mainly] induces sweat loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] exterior deficiency spontaneous perspiration, headache due to yin-deficiency avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of sympathetic ophthalmia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing sympathetic ophthalmia.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of sympathetic ophthalmia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Holotrichia diomphalia Bates 5 parts, Herba Camptosori Sibirici 6 parts, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 parts, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 parts, Flos Pyrethri tatsienensis 9 parts, Radix Stephaniae Epigaeae 4 parts, yoke grass 15 parts, Herba Schizonepetae 30 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and sympathetic ophthalmia patient 230 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 120 example and matched group 110 example at random, treatment group man 52 example, female 68 example, 20 ~ 75 years old age, the course of disease 3 ~ 20 years; Matched group man 64 example, female 46 example, 19 ~ 70 years old age, the course of disease 3 ~ 20 years.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national sympathetic ophthalmia clinical speciality:
(1) primary disease morbidity suddenly, and initial stage patient only tells strong eye blurred vision, and cotton-shaped shadow is waved at the moment, and the state of an illness often increases the weight of thereupon, vision degradation, metamorphopsia, and eye is shed tears, ciliary congestion, and aqueous humor is muddy, and front portion shows as iridocyclitis.
(2) fundus Oculi Manifestations: vitreous body agglomerate flocculent turbidity, optic disc is congested, and HUANGBAI(sic) speckle, appears in retinal edema, Dalen mono-Fuchs corpusculum, detachment of retina, and the later stage is sunset clouds sample optical fundus.
(3) some patients occurs that hair bleaches, and comes off, and the depigmentation appears in skin, audition generation obstacle.
(4) exciting eye inflammation is sent out or is increased the weight of, and hinder uvea chronic inflammatory disease often and fail to be controlled rapidly, it still has caused by development.
(5) underwent eye-ground vascular fluorescence visualization: the Fluorescein Leakage point be dispersed under Posterior pole retina, increase and be fused into many cryptomeres subretinal fluid accumulate district.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times, one month course for the treatment of.
The oral cyclophosphamide 50mg of matched group, every day 3 times is oral; External 1% atropine eye drop eye, 1 ~ 2 times/day; 1% atropine eye ointment is coated with in eye conjunctival sac for 1 time every night.One month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: vision improves more than >=2 row and the visual field expands more than 5 °, and intraocular pressure controls at below 15mmHg;
Effective: vision improves 1 row and the visual field is constant or expand≤5 °, and intraocular pressure controls within the scope of 15 ~ 21mmHg;
Invalid: treatment Patients Before And After is without any change, and intraocular pressure is greater than more than 21mmHg.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment sympathetic ophthalmia, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Holotrichia diomphalia Bates 5 grams, Herba Camptosori Sibirici 6 grams, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 grams, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 grams, Flos Pyrethri tatsienensis 9 grams, Radix Stephaniae Epigaeae 4 grams, yoke grass 15 grams, Herba Schizonepetae 30 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of sympathetic ophthalmia.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Holotrichia diomphalia Bates 5 grams, Herba Camptosori Sibirici 6 grams, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 grams, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 grams, Flos Pyrethri tatsienensis 9 grams, Radix Stephaniae Epigaeae 4 grams, yoke grass 15 grams, Herba Schizonepetae 30 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of sympathetic ophthalmia.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Holotrichia diomphalia Bates 5 grams, Herba Camptosori Sibirici 6 grams, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 grams, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 grams, Flos Pyrethri tatsienensis 9 grams, Radix Stephaniae Epigaeae 4 grams, yoke grass 15 grams, Herba Schizonepetae 30 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of sympathetic ophthalmia.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of sympathetic ophthalmia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Holotrichia diomphalia Bates 5 parts, Herba Camptosori Sibirici 6 parts, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 parts, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 parts, Flos Pyrethri tatsienensis 9 parts, Radix Stephaniae Epigaeae 4 parts, yoke grass 15 parts, Herba Schizonepetae 30 parts.
2. a kind of Chinese medicine being used for the treatment of sympathetic ophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: Holotrichia diomphalia Bates 5 parts, Herba Camptosori Sibirici 6 parts, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 parts, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 parts, Flos Pyrethri tatsienensis 9 parts, Radix Stephaniae Epigaeae 4 parts, yoke grass 15 parts, Herba Schizonepetae 30 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of sympathetic ophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: Holotrichia diomphalia Bates 5 parts, Herba Camptosori Sibirici 6 parts, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 parts, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 parts, Flos Pyrethri tatsienensis 9 parts, Radix Stephaniae Epigaeae 4 parts, yoke grass 15 parts, Herba Schizonepetae 30 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of sympathetic ophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: Holotrichia diomphalia Bates 5 parts, Herba Camptosori Sibirici 6 parts, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 15 parts, Huperzia serrata (Thunb) Trev. F. Intermedia (Nakai) Ching. 9 parts, Flos Pyrethri tatsienensis 9 parts, Radix Stephaniae Epigaeae 4 parts, yoke grass 15 parts, Herba Schizonepetae 30 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN201510527517.0A CN105030999A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine for treating sympathetic ophthalmia |
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| CN201510527517.0A CN105030999A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine for treating sympathetic ophthalmia |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660226A (en) * | 2004-12-29 | 2005-08-31 | 王四旺 | 'Wuzi Mingmu' pill and preparing technique |
| CN104435457A (en) * | 2013-09-12 | 2015-03-25 | 雷华亮 | Chinese medicinal composition for treatment of edema and ophthalmia and preparation method thereof |
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2015
- 2015-08-25 CN CN201510527517.0A patent/CN105030999A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660226A (en) * | 2004-12-29 | 2005-08-31 | 王四旺 | 'Wuzi Mingmu' pill and preparing technique |
| CN104435457A (en) * | 2013-09-12 | 2015-03-25 | 雷华亮 | Chinese medicinal composition for treatment of edema and ophthalmia and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 罗良涛，刘伟编著: "《难病奇方系列丛书 三仁汤》", 31 January 2013, 中国医药科技出版社 * |
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Application publication date: 20151111 |