CN1657080A - Oral liquid formula used for treating postparatum blood vacuity and its preparation method - Google Patents

Abstract

A Chinese medicine in the form of oral liquid for treating the puerperal anemia, incessant dripping of lochia, deficiency of blood, etc is prepared from 9 Chniese medicinal materials including Chinese angelica root, white peony root, Chuan-xiong rhizome, astragalus root, etc through proportional mixing, washing, distilling, percolating and concentrating.

Description

A kind of oral liquid prescription that is used for the blood deficiency in puerperal and preparation method thereof

The present invention relates to a kind of is that preparation of raw material is refined oral liquid prescription that is used for the blood deficiency in puerperal that forms and preparation method thereof with Chinese medicine.

The puerpera is many with diseases such as blood stasis, blood deficiency new puerperal, and the clinical treatment method is also more.But for patient, puerperal is weak, and resistance is relatively low, and selected medicine should act on mitigation, dosage is accurate, convenient again use, absorption easily.

Purpose of the present invention just provides a kind of oral liquid prescription that is used for the blood deficiency in puerperal and preparation method thereof.

The present invention in conjunction with the clinical verification of two more than ten years, is a component with Chinese medicine according to the theory of Chinese medical science and the principles of formulating prescriptions, makes oral liquid through refinement.

Oral liquid prescription of the present invention, prepare with following weight ratio:

Radix Angelicae Sinensis 10-20 Radix Paeoniae Alba 10-40 Rhizoma Cyperi (processed) 10-30 Rhizoma Chuanxiong 10-30

Herba Leonuri 10-20 Colla Corii Asini 20-30 Radix Astragali 20-30 Fructus Jujubae 20-30

Fructus Amomi 20-30 Fructus Crataegi (parched to brown) 10-40

Its preparation method is:

(1) cleaning, drying: with Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Cyperi (processed), Rhizoma Chuanxiong, Herba Leonuri, the Radix Astragali, Fructus Jujubae, Fructus Amomi, Fructus Crataegi (parched to brown) selected after, cleaning, drying;

(2) distillation: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba Leonuri, Fructus Amomi are extracted its volatile oil with the way of distillation, the device harvesting in addition of the aqueous solution after the distillation;

(3) percolation: the medicinal residues after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba Leonuri, the Fructus Amomi distillation and the Radix Paeoniae Alba, Rhizoma Cyperi (processed), Fructus Crataegi (parched to brown), the Radix Astragali are made solvent by percolation (2000 editions " Chinese pharmacopoeia appendix 10) with 70% ethanol, flood after 24 hours, with the speed percolation of per minute 1-3 milliliter, the liquid of will filtering is then collected; Simultaneously ethanol is reclaimed, standby;

(4) decoct: said medicine and Fructus Jujubae decoct with water secondary, and collecting decoction leaches standby;

(5) molten: Colla Corii Asini is added in the rustless steel container, and it is an amount of to add water, heats to 80 ° of C, treat its molten after, other usefulness of purchasing;

(6) concentrate: above-mentioned percolate, decoction liquor, molten liquid are mixed and slowly stirring, it is fully mixed, leave standstill, filter, filtrate concentrates;

(7) adjust: described concentrated solution is mixed with volatile oil in the above-mentioned steps 2, add an amount of antiseptic, correctives, adjust pH value, regulate total amount, promptly get stock solution;

(8) sterilization: use ultrasonic Treatment 50 minutes down at low temperature (≤40 ℃);

(9) packing: with above-mentioned sterilized solution packing;

Finished product packing after tested, then warehouse-in thereafter.

Clinical Practice of the present invention shows following advantage:

1, selecting the natural plants material of benefiting QI for activating blood circulation, spleen benefiting and stimulating the appetite for use is raw material, extracts its active ingredient, evident in efficacy for prolonged lochia, poor appetite, symptom such as weak, and without any side effects.

2, mouthfeel is good, and taking convenience absorbs soon, and effect relaxes, and is easy to patient and accepts.

3, accurate, the control easily of dosage.

4, steady quality, easily preservation.

Embodiment:

Claim raw material of Chinese medicine by following weight proportion choosing:

Radix Angelicae Sinensis 20 Radix Paeoniae Albas 12 Rhizoma Cyperi (processed) 15 Rhizoma Chuanxiongs 12 Herba Leonuri 12

Colla Corii Asini 20 Radixs Astragali 20 Fructus Jujubaes 20 Fructus Amomis 20 Fructus Crataegi (parched to brown)s 20

Adopt above-mentioned preparation method to make finished product.

Description of drawings:

Fig. 1 is a process chart of the present invention.

The main composition that extracts in the Chinese medicine material to this oral liquid carries out brief analysis:

Radix Angelicae Sinensis mainly extracts its volatile oil, wherein contains multiple lactone and Amino Acid Composition, has Excited uterus and suppress uterus, arrhythmia, the little blood vessel of expansion, suppress platelet aggregation, The effects such as anti-inflammation. The root of herbaceous peony is mainly extracted its Paeoniflorin, and central nervous system is had inhibition Effect, expansible coronary vasodilator, nutrition haemocyte. Rhizoma cyperi is the common medicine of gynaecology's vital energy regualting and blood circulation-promoting, Theory of traditional Chinese medical science is thought " rhizome of nutgrass flatsedge regulate the flow of vital energy blood, married woman's usefulness ", mainly extracts its cardiac glycoside flavones Compound, the effect of analgesia, anti-inflammatory are arranged, invigorating blood circulation.

This oral liquid is according to the new physiological and pathological feature afterwards that produces of puerpera, according to the group of motherland's medical science Side's principle is selected medicine among nourishing qi and blood, the spleen benefiting and stimulating the appetite, have tonifying Qi, nourish blood, invigorate blood circulation, The effect of appetizing can improve puerpera's body's immunity, improve rapidly puerpera's postpartum anemia, Weak, receive the symptoms such as poor, lochiorrhagia, be that a kind of comparatively desirable puerpera nourishes medicine.

Claims (2)

1, a kind of oral liquid prescription that is used for the blood deficiency in puerperal and preparation method thereof is characterized in that its composition of raw materials prepares with following weight ratio:

Radix Angelicae Sinensis 10-20 Radix Paeoniae Alba 10-40 Rhizoma Cyperi (processed) 10-30 Rhizoma Chuanxiong 10-30

Herba Leonuri 10-20 Colla Corii Asini 20-30 Radix Astragali 20-30 Fructus Jujubae 20-30

Fructus Amomi 20-30 Fructus Crataegi (parched to brown) 10-40.

2, a kind of oral liquid prescription that is used for the blood deficiency in puerperal and preparation method thereof is characterized in that oral liquid is prepared with following step:

(1) cleaning, drying: with Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Cyperi (processed), Rhizoma Chuanxiong, Herba Leonuri, the Radix Astragali, Fructus Jujubae, Fructus Amomi, Fructus Crataegi (parched to brown) selected after, cleaning, drying;

(2) distillation: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba Leonuri, Fructus Amomi are extracted its volatile oil with the way of distillation, the device harvesting in addition of the aqueous solution after the distillation;

(3) percolation: the medicinal residues after Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba Leonuri, the Fructus Amomi distillation and the Radix Paeoniae Alba, Rhizoma Cyperi (processed), Fructus Crataegi (parched to brown), the Radix Astragali are made solvent by percolation (2000 editions " Chinese pharmacopoeia appendix 10) with 70% ethanol, flood after 24 hours, with the speed percolation of per minute 1-3 milliliter, the liquid of will filtering is then collected; Simultaneously ethanol is reclaimed, standby;

(4) decoct: said medicine and Fructus Jujubae decoct with water secondary, and collecting decoction leaches standby;

(5) molten: Colla Corii Asini is added in the rustless steel container, and it is an amount of to add water, heats to 80 ℃, treat its molten after, other usefulness of purchasing;

(6) concentrate: above-mentioned percolate, decoction liquor, molten liquid are mixed and slowly stirring, it is fully mixed, leave standstill, filter, filtrate concentrates;

(7) adjust: described concentrated solution is mixed with volatile oil in the above-mentioned steps 2, add an amount of antiseptic, correctives, adjust pH value, regulate total amount, promptly get stock solution;

(8) sterilization: use ultrasonic Treatment 50 minutes down at low temperature (≤40 ℃);

(9) packing: with above-mentioned sterilized solution packing.

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