CN103610043A - Oral liquid capable of improving postpartum anemia and preparation method thereof - Google Patents
Oral liquid capable of improving postpartum anemia and preparation method thereof Download PDFInfo
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- CN103610043A CN103610043A CN201310584119.3A CN201310584119A CN103610043A CN 103610043 A CN103610043 A CN 103610043A CN 201310584119 A CN201310584119 A CN 201310584119A CN 103610043 A CN103610043 A CN 103610043A
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- oral liquid
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- anemia
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- 239000007788 liquid Substances 0.000 title claims abstract description 27
- 208000007502 anemia Diseases 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 210000000582 semen Anatomy 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 108010010803 Gelatin Proteins 0.000 claims description 10
- 239000009636 Huang Qi Substances 0.000 claims description 10
- 229920000159 gelatin Polymers 0.000 claims description 10
- 239000008273 gelatin Substances 0.000 claims description 10
- 235000019322 gelatine Nutrition 0.000 claims description 10
- 235000011852 gelatine desserts Nutrition 0.000 claims description 10
- 241000736199 Paeonia Species 0.000 claims description 8
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 8
- 235000003599 food sweetener Nutrition 0.000 claims description 8
- 239000003765 sweetening agent Substances 0.000 claims description 8
- 238000005352 clarification Methods 0.000 claims description 7
- 238000011049 filling Methods 0.000 claims description 7
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 5
- 239000008236 heating water Substances 0.000 claims description 5
- 239000004302 potassium sorbate Substances 0.000 claims description 5
- 229940069338 potassium sorbate Drugs 0.000 claims description 5
- 235000010241 potassium sorbate Nutrition 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 244000025254 Cannabis sativa Species 0.000 claims description 4
- AHRFRRASJMTTQU-UHFFFAOYSA-N 6-methyl-2,2-dioxooxathiazin-4-one;potassium Chemical compound [K].CC1=CC(=O)NS(=O)(=O)O1 AHRFRRASJMTTQU-UHFFFAOYSA-N 0.000 claims description 2
- 108010011485 Aspartame Proteins 0.000 claims description 2
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 2
- 239000000605 aspartame Substances 0.000 claims description 2
- 229960003438 aspartame Drugs 0.000 claims description 2
- 235000010357 aspartame Nutrition 0.000 claims description 2
- 235000009508 confectionery Nutrition 0.000 claims description 2
- 230000001976 improved effect Effects 0.000 claims description 2
- 238000002791 soaking Methods 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 238000002156 mixing Methods 0.000 abstract description 4
- 230000035935 pregnancy Effects 0.000 abstract description 3
- 108010052008 colla corii asini Proteins 0.000 abstract 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 229920001661 Chitosan Polymers 0.000 abstract 1
- 241000207925 Leonurus Species 0.000 abstract 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 abstract 1
- 240000008866 Ziziphus nummularia Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 24
- 210000004369 blood Anatomy 0.000 description 21
- 210000004185 liver Anatomy 0.000 description 10
- 239000000047 product Substances 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 6
- 239000008213 purified water Substances 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 3
- 235000013402 health food Nutrition 0.000 description 3
- 229940023492 oral liquid product Drugs 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 210000002216 heart Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 229930182490 saponin Natural products 0.000 description 2
- 150000007949 saponins Chemical class 0.000 description 2
- 206010067703 Intrapartum haemorrhage Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
Abstract
The invention relates to an oral liquid capable of improving postpartum anemia and a preparation method thereof. The preparation method comprises the following steps: by taking colla corii asini, angelica sinensis, fructus amomi, astragalus membranaceus, leonurus, semen sesami nigrum, jujube and other traditional Chinese medicines as the raw materials, decocting and concentrating all traditional Chinese medicines except colla corii asini into a medicine liquid; adding melted colla corii asini and chitosan; uniformly agitating; adding auxiliary materials; and then mixing to obtain the oral liquid. The oral liquid has the effects of preventing and improving postpartum anemia, and can relieve anemia in the pregnancy duration and anemia caused by postpartum hemorrhage.
Description
Technical field
The present invention relates to a kind of health food, particularly relate to a kind of take Chinese medicine as raw material prepare for improving health food of postpartum anemia and preparation method thereof.
Background technology
The traditional Chinese medical science thinks that people is an organic whole, and " gas ", " blood " are the basic of its health, and full people is healthy, long-lived for qi and blood.Postpartum anemia is a kind of of anaemia, and the reason of its generation mainly contains following two aspects: once being that pregnancy duration has Anemia, but improved in time, minute puerperium losing blood in various degree increased the weight of severity of anemia; The 2nd, pregnancy duration pregnant woman qi and blood is exuberant, and because intrapartum hemorrhage is too much, the two mistake of qi and blood caused.The traditional Chinese medical science is thought: gas can promote blood operation, and blood can deliver gas, and qi and blood grows mutually, and deficiency of QI causing insufficiency of blood, blood is the deficiency of vital energy at least, therefore be generally qi-blood tonifying on tcm clinical practice.
At present, domestic anaemia health products have 184 kinds, and majority is herbal mixture product, and 3 kinds of import anaemia health products are mainly nutrient and supplement series products.In the majority to contain the Radix Astragali, Radix Angelicae Sinensis and donkey-hide gelatin person again in herbal mixture product.
Summary of the invention
The object of this invention is to provide a kind of take Chinese medicine as raw material prepare for improving the Nutrious health-care oral tonic of postpartum anemia, and the preparation method of this oral liquid.
The oral liquid that improves postpartum anemia of the present invention is to be made by the raw material of following parts by weight:
Radix Angelicae Sinensis 10-20 weight portion fructus amomi 10-40 weight portion root of herbaceous peony 15-40 weight portion
Female careless 10-30 weight portion Radix Astragali 15-40 weight portion charred FRUCTUS CRATAEGI 10-40 weight portion
Semen sesami nigrum 10-60 weight portion date 15-45 weight portion donkey-hide gelatin 5-30 weight portion.
The preparation method that the present invention improves the oral liquid of postpartum anemia comprises the following steps:
1) get Radix Angelicae Sinensis, fructus amomi, the root of herbaceous peony, female grass, the Radix Astragali, charred FRUCTUS CRATAEGI, Semen sesami nigrum, the date of described parts by weight, with the water soaking 30min of 8 times of medicinal material weight, decoct 1.5h, filter; Filter residue adds same water gaging again, decocts 0.5h, filters; Merge decoction liquor twice, 70 ℃ of concentrates that are concentrated into relative density 1.04-1.30,4 ℃ of standing 24h, filter to obtain clarification liquid;
2) get the donkey-hide gelatin water-bath molten of described parts by weight, join in clarification liquid, then add shitosan, making shitosan final concentration is heating water bath 30min under 0.05%, 60 ℃ of stirring, and standing 24h filters the filling oral liquid of making.
The common process of producing according to oral liquid, the present invention also adds appropriate sweetener and potassium sorbate in liquid.
Wherein, described sweetener can select sucrose, Aspartame, Steviosin, 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt, sweet mellow wine etc. to can be used for one or more in the sweetener of food or medicine.
The present invention be take Chinese medicine and is made the oral liquid health food that improves postpartum anemia as raw material components, wherein:
Radix Angelicae Sinensis: return liver, the heart, the spleen channel; Get it and enrich blood and invigorate blood circulation, menstruction regulating and pain relieving effect, the key medicine of gynaecology;
Fructus amomi: return the spleen channel, stomach warp, kidney channel; Get that it is warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy;
The root of herbaceous peony: return liver, the spleen channel; Nourishing blood and liver, slow in pain relieving, astringe yin is received sweat, can clear and coherent blood vessels, slow in, dispelling malignant blood;
Female grass: the thoughts of returning home, liver, urinary bladder channel; Promoting blood circulation, inducing diuresis for removing edema is clearing heat and detoxicating; Can be used for prolonged lochia;
The Radix Astragali: return liver, spleen, lung, kidney channel; Get the admittedly de-effect of its invigorating qi for consolidating superficies, arrest sweating, take good care of irritability, can beneficial blood tonifying Qi;
Charred FRUCTUS CRATAEGI: return Pi, stomach, Liver Channel; Spleen benefiting and stimulating the appetite, relieving dyspepsia, promoting blood circulation and removing blood stasis;
Semen sesami nigrum: return liver, kidney, large intestine channel; Get its filling liver kidney, the effect of benefiting essence-blood, can filling liver kidney, moisturizing viscera, beneficial strength;
Date: return spleen, stomach warp; Can tonifying middle-Jiao and Qi, nourishing blood and tranquilization;
Donkey-hide gelatin: return lung, the heart, liver, kidney channel; The enriching yin of can enriching blood, moisturizes, and hemostasis, controls postpartum anemia.
In product of the present invention, the Radix Astragali, Radix Angelicae Sinensis, donkey-hide gelatin respectively can tonifying Qi, enrich blood, and kidney-replenishing and enriching yin, have prevention effect for the anaemia causing because of insufficiency of vital energy and blood; Fructus amomi, female grass can be antiabortive and manage property after lose blood; Be aided with again Semen sesami nigrum, date, tonifying Qi is enriched blood, qi-blood tonifying, improves postpartum anemia.Total polysaccharide yield 2-8% in the oral liquid of making, total saponin content 0.5-3g/100g, has prevention and improvement effect for postpartum anemia.Meanwhile, product of the present invention is without toxicity, side effect, and mouthfeel is good, is convenient to take.
The specific embodiment
Embodiment 1
Get Radix Angelicae Sinensis 12 weight portions selected, that clean, fructus amomi 15 weight portions, the root of herbaceous peony 20 weight portions, female careless 20 weight portions, the Radix Astragali 20 weight portions, charred FRUCTUS CRATAEGI 12 weight portions, Semen sesami nigrum 12 weight portions, date 20 weight portions mixing, the purified water that adds 1000 weight portions, under normal temperature, soak 30min, decoct again 1.5h, filter to obtain a decoction liquor.Filter residue after once decocting adds the purified water of 1000 weight portions again, decocts 0.5h, filters to obtain secondary decoction liquor.Merge decoction liquor twice, 70 ℃ are condensed into the concentrate that relative density is 1.04-1.30.4 ℃ of standing 24h, filter to obtain clarification liquid.
Get 12 weight portion donkey-hide gelatin, with a small amount of water water-bath molten, join in above-mentioned concentrated medicament.Add shitosan, making shitosan final concentration is heating water bath 30min under 0.05%, 60 ℃ of stirring again, and standing 24h filters, and adds appropriate sweetener and potassium sorbate, mixes, filling, sealing, and flowing steam sterilization, obtains oral liquid product.Total polysaccharide yield 2-8% wherein, total saponin content 0.5-3g/100g.
Embodiment 2
Get Radix Angelicae Sinensis 18 weight portions selected, that clean, fructus amomi 18 weight portions, the root of herbaceous peony 25 weight portions, female careless 25 weight portions, the Radix Astragali 15 weight portions, charred FRUCTUS CRATAEGI 15 weight portions, Semen sesami nigrum 15 weight portions, date 15 weight portions mixing, the purified water that adds 1200 weight portions, under normal temperature, soak 30min, decoct again 1.5h, filter to obtain a decoction liquor.Filter residue after once decocting adds the purified water of 1200 weight portions again, decocts 0.5h, filters to obtain secondary decoction liquor.Merge decoction liquor twice, 70 ℃ are condensed into the concentrate that relative density is 1.04-1.30.4 ℃ of standing 24h, filter to obtain clarification liquid.
Get 15 weight portion donkey-hide gelatin, with a small amount of water water-bath molten, join in above-mentioned concentrated medicament.Add shitosan, making shitosan final concentration is heating water bath 30min under 0.05%, 60 ℃ of stirring again, and standing 24h filters, and adds appropriate sweetener and potassium sorbate, mixes, filling, sealing, and flowing steam sterilization, obtains oral liquid product.
Embodiment 3
Get Radix Angelicae Sinensis 15 weight portions selected, that clean, fructus amomi 20 weight portions, the root of herbaceous peony 20 weight portions, female careless 23 weight portions, the Radix Astragali 18 weight portions, charred FRUCTUS CRATAEGI 18 weight portions, Semen sesami nigrum 13 weight portions, date 18 weight portions mixing, the purified water that adds 1200 weight portions, under normal temperature, soak 30min, decoct again 1.5h, filter to obtain a decoction liquor.Filter residue after once decocting adds the purified water of 1200 weight portions again, decocts 0.5h, filters to obtain secondary decoction liquor.Merge decoction liquor twice, 70 ℃ are condensed into the concentrate that relative density is 1.04-1.30.4 ℃ of standing 24h, filter to obtain clarification liquid.
Get 18 weight portion donkey-hide gelatin, with a small amount of water water-bath molten, join in above-mentioned concentrated medicament.Add shitosan, making shitosan final concentration is heating water bath 30min under 0.05%, 60 ℃ of stirring again, and standing 24h filters, and adds appropriate sweetener and potassium sorbate, mixes, filling, sealing, and flowing steam sterilization, obtains oral liquid product.
Claims (4)
1. improve an oral liquid for postpartum anemia, by the raw material of following parts by weight, made:
Radix Angelicae Sinensis 10-20 weight portion fructus amomi 10-40 weight portion root of herbaceous peony 15-40 weight portion
Female careless 10-30 weight portion Radix Astragali 15-40 weight portion charred FRUCTUS CRATAEGI 10-40 weight portion
Semen sesami nigrum 10-60 weight portion date 15-45 weight portion donkey-hide gelatin 5-30 weight portion.
2. claim 1 is improved the preparation method of the oral liquid of postpartum anemia, comprises the following steps:
1) get Radix Angelicae Sinensis, fructus amomi, the root of herbaceous peony, female grass, the Radix Astragali, charred FRUCTUS CRATAEGI, Semen sesami nigrum, the date of described parts by weight, with the water soaking 30min of 8 times of medicinal material weight, decoct 1.5h, filter; Filter residue adds same water gaging again, decocts 0.5h, filters; Merge decoction liquor twice, 70 ℃ of concentrates that are concentrated into relative density 1.04-1.30,4 ℃ of standing 24h, filter to obtain clarification liquid;
2) get the donkey-hide gelatin water-bath molten of described parts by weight, join in clarification liquid, then add shitosan, making shitosan final concentration is heating water bath 30min under 0.05%, 60 ℃ of stirring, and standing 24h filters the filling oral liquid of making.
3. the preparation method who improves the oral liquid of postpartum anemia according to claim 2, is characterized in that being also added with in described oral liquid sweetener and potassium sorbate.
4. the preparation method who improves the oral liquid of postpartum anemia according to claim 3, is characterized in that described sweetener is one or more in sucrose, Aspartame, Steviosin, 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt, sweet mellow wine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310584119.3A CN103610043B (en) | 2013-11-20 | 2013-11-20 | Oral liquid capable of improving postpartum anemia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310584119.3A CN103610043B (en) | 2013-11-20 | 2013-11-20 | Oral liquid capable of improving postpartum anemia and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103610043A true CN103610043A (en) | 2014-03-05 |
| CN103610043B CN103610043B (en) | 2015-07-22 |
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| CN201310584119.3A Active CN103610043B (en) | 2013-11-20 | 2013-11-20 | Oral liquid capable of improving postpartum anemia and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075881A (en) * | 1992-12-15 | 1993-09-08 | 吉林省敦化市制药厂 | Blood nourishing decoction |
| CN1657080A (en) * | 2004-03-09 | 2005-08-24 | 刘建清 | Oral liquid formula used for treating postparatum blood vacuity and its preparation method |
| CN1872150A (en) * | 2006-05-09 | 2006-12-06 | 株洲千金药业股份有限公司 | Composition of Chinese traditional medicine for replenishing qi and the blood |
| JP2007161675A (en) * | 2005-12-16 | 2007-06-28 | Taisho Pharmaceut Co Ltd | Fatigue-improving internal medicine |
-
2013
- 2013-11-20 CN CN201310584119.3A patent/CN103610043B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075881A (en) * | 1992-12-15 | 1993-09-08 | 吉林省敦化市制药厂 | Blood nourishing decoction |
| CN1657080A (en) * | 2004-03-09 | 2005-08-24 | 刘建清 | Oral liquid formula used for treating postparatum blood vacuity and its preparation method |
| JP2007161675A (en) * | 2005-12-16 | 2007-06-28 | Taisho Pharmaceut Co Ltd | Fatigue-improving internal medicine |
| CN1872150A (en) * | 2006-05-09 | 2006-12-06 | 株洲千金药业股份有限公司 | Composition of Chinese traditional medicine for replenishing qi and the blood |
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