CN1650894A - 从纯中药制剂中提取具有改善性生活质量的复方雄蛾强肾原料药的方法 - Google Patents
从纯中药制剂中提取具有改善性生活质量的复方雄蛾强肾原料药的方法 Download PDFInfo
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Abstract
Description
组别 | 动物(只) | Pmol/ml( X±SD) | P值 | 备注 |
空白对照组(生理盐水) | 10 | 2.59±0.48 | ||
美国伟哥组6mg/Kg | 10 | 4.53±0.67 | P<0.001* | 与对照组比较 |
美国伟哥组12mg/Kg | 10 | 4.42±0.97 | P<0.001* | 与对照组比较 |
复方制品组200mg/Kg | 10 | 3.88±1.01 | P<0.001* | 与对照组比较 |
复方制品组400mg/Kg | 10 | 2.80±0.18 | P<0.2 | 与对照组比较 |
组别 | 动物(只) | Pmol/ml( X±SD) | P值 | 备注 |
空白对照组(生理盐水) | 10 | 0.25±0.05 | ||
美国伟哥组6mg/Kg | 10 | 0.40±0.26 | P<0.1 | 与对照组比较 |
美国伟哥组12mg/Kg | 10 | 0.53±0.12 | P<0.001 | 与对照组比较 |
复方制品组200mg/Kg | 10 | 0.45±0.17 | P<0.01 | 与对照组比较 |
复方制品组400mg/Kg | 10 | 0.43±0.13 | P<0.001 | 与对照组比较 |
例数 | 性别 | 平均年龄(岁) | 平均病程(年) | 平均积分 | 门诊 | 住院 | |
男 | 女 | ||||||
30 | 24 | 6 | 51.23 | 2.86 | 31.2 | 26 | 4 |
例数 | 显效例(%) | 有效例(%) | 无效例(%) | 总有效率(%) |
30 | 4(13.33) | 23(76.67) | 3(10) | 90 |
病程 | 例数 | 显效例(%) | 有效例(%) | 无效例(%) | 总有效率(%) | P值 |
一年以下 | 1 | 1(100) | 100 | R=0.47595%可信区间0.353-0.914 | ||
一~三年 | 20 | 2(10) | 15(75) | 3(15) | 85 | R=0.5 |
三年以上 | 9 | 2(22.22) | 7(77.78) | 100 | R=0.380695%可信区间0.2340-0.5271 |
疗程 | 例数 | 显效例(%) | 有效例(%) | 无效例(%) | 总有效率(%) | P值 |
第一 | 30 | 1(3.33) | 29(96.67) | 3.33 | R=0.935695%可信区间0.8579-1.0132 | |
第二 | 30 | 13(43.33) | 17(56.67) | 43.33 | R=0.762295%可信区间0.6846-0.8399 | |
第三 | 30 | 4(13.33) | 23(76.67) | 3(10) | 90 | R=0.5 |
年龄组 | 例数 | 显效例(%) | 有效例(%) | 无效例(%) | 总有效率(%) | P值 |
25~44岁 | 12 | 3(25) | 9(75) | 100 | <0.001 | |
45~59岁 | 7 | 1(14.285) | 5(71.43) | 1(14.285) | 85.71 | <0.001 |
60~70岁 | 11 | 9(81.82) | 2(18.18) | 81.82 | <0.001 |
性别 | 例数 | 显效例(%) | 有效例(%) | 无效例(%) | 总有效率(%) | P值 |
男 | 24 | 4(16.67) | 17(70.83) | 3(12.5) | 87.5 | <0.001 |
女 | 6 | 6(100) | <0.001 |
例数 | 治疗前(x±SD) | 治疗后(x±SD) | P值 | ||||
IgG | IgA | IgG | IgG | IgA | IgM | ||
30 | 12.68±1.93 | 2.18±0.88 | 1.22±0.24 | 12.78±1.56 | 2.06±0.85 | 1.28±0.28 | IgG>0.50IgG>0.10IgG>0.20 |
症状 | 治疗前(例数%) | 治疗后未改善(例数%) | P值 | ||||
一级 | 二级 | 三级 | 一级 | 二级 | 三级 | ||
形寒肢冷 | 2(6.9) | 10(34.48) | 17(58.62) | 16(55.17) | 8(27.59) | <0.001 | |
腰膝酸软 | 0 | 7(25) | 21(75) | 18(64.29 | 5(17.86) | 1(3.57) | <0.001 |
尿频不利 | 16(69.57) | 4(17.39) | 3(13.04) | 9(39.13) | 4(17.39) | <0.001 | |
阳痿遗精、早泄 | 10(52.63) | 4(21.05) | 5(26.32) | 12(63.16) | 2(10.53) | <0.001 | |
神疲健忘 | 17(68) | 3(12) | 5(20) | 11(44) | 3(12) | <0.001 |
时间 | 例数 | 肝功 | 血常规 | 尿常规 | |||
正常 | 异常 | 正常 | 异常 | 正常 | 异常 | ||
治疗前 | 30 | 30 | 30 | 30 | |||
治疗后 | 30 | 30 | 30 | 30 |
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CNB2004100011464A CN100421705C (zh) | 2004-02-02 | 2004-02-02 | 从纯中药制剂中提取具有改善性生活质量的复方雄蛾强肾原料药的方法 |
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CN100421705C CN100421705C (zh) | 2008-10-01 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105412516A (zh) * | 2015-12-17 | 2016-03-23 | 沈阳飞龙伟业制药有限公司 | 一种参蛾助阳合剂及其制备方法 |
CN105486764A (zh) * | 2014-09-19 | 2016-04-13 | 天士力制药集团股份有限公司 | 一种坤灵丸的气相指纹图谱的分析方法及其应用 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1128626C (zh) * | 2000-03-15 | 2003-11-26 | 蒲荣 | 一种益肾壮骨保健药酒 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105486764A (zh) * | 2014-09-19 | 2016-04-13 | 天士力制药集团股份有限公司 | 一种坤灵丸的气相指纹图谱的分析方法及其应用 |
CN105486764B (zh) * | 2014-09-19 | 2019-05-17 | 天士力医药集团股份有限公司 | 一种坤灵丸的气相指纹图谱的分析方法及其应用 |
CN105412516A (zh) * | 2015-12-17 | 2016-03-23 | 沈阳飞龙伟业制药有限公司 | 一种参蛾助阳合剂及其制备方法 |
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Effective date of registration: 20140207 Address after: 110300 Xinmin Industrial Zone, Liaoning Patentee after: Shenyang Feilong Pharmaceutical Co.,Ltd. Address before: Hunnan New District Road Shenyang city Liaoning province 110179 No. 9 A203 Patentee before: Jiang Wei |
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CX01 | Expiry of patent term | ||
CX01 | Expiry of patent term |
Granted publication date: 20081001 |